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Great Dane puppies and dogs in Mississippi

Looking for a Great Dane puppy or dog in Mississippi? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane in Mississippi Search for a Great Dane puppy or dog Great Dane puppies and dogs in Mississippi cities Great Dane shelters and rescues in Mississippi Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Mississippi

Below are our newest added Great Danes available for adoption in Mississippi. To see more adoptable Great Danes in Mississippi, use the search tool below to enter specific criteria!
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Barlow 060101A

Great Dane/Setter (Unknown Type)

Male, 1 yr 3 mos
Amory, MS
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Trinity

Great Dane/Hound (Unknown Type)

Female, 2 yrs 2 mos
Cleveland, MS
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Apply online at https://www.shelterluv.com/matchme/adopt/CBC/Dog Applying does not commit you to adopting this specific animal. We do not do same-day adoptions without a pre-approved adoption application already on file. Please give us a call for any questions about our adoption process! We are happy to help! Our $70 adoption fee includes spay/neuter prior to adoption, age-appropriate vaccines, deworming, ID tag, heartworm test if over 6 months of age, and microchip. Please do not contact us through Petfinder. Due to the number of inquiries we receive, we recommend contacting us by phone at 662-846-1155 or by email at animalshelter@cityofclevelandms.com if you have a specific question about an animal. We will not schedule an adoption until an adopter has filled out an adoption application.

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Lexington

Great Dane/Labrador Retriever

Male, Adult
Jackson, MS
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
Lexington is a tall, handsome gentle giant with the sweetest soul. This affectionate guy loves being close to his people, going for walks, playing, and—most importantly—TREATS! He’s smart, easy to walk, and has the most adorable habit of leaning his big ol’ body against you for love. Lexington enjoys having his people nearby and would thrive in a home that appreciates a loyal, affectionate companion. He can be selective with other dogs, so slow, proper introductions are important. Give Lexington a little time to settle in, and you’ll discover one incredibly loving best friend. This sweet grey gentleman is ready to trade shelter life for a couch, some snacks, and a family of his very own.September 1, 2026, 1:46 am

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Flint

Great Dane

Male, 8 mos
Gulfport, MS
Size
(when grown) Small 25 lbs (11 kg) or less
Details
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Story
Meet Flint!Some dogs have a way of making every day feel a little brighter, and Flint is one of them.This happy, goofy boy is a bundle of sunshine with a heart full of love and a tail that never seems to stop wagging. He lives for playtime, whether he`s chasing his favorite toy, exploring the yard, or bouncing around with that signature puppy enthusiasm. And wherever you go, don`t be surprised if Flint is right behind you! Being close to his people is one of his favorite places to be.Flint came to the shelter as a young puppy and has spent most of his life growing into the wonderful dog he is today. Through it all, he`s held onto his joyful spirit. Every day he greets people with excitement, hoping that today might be the day someone chooses him.He`s as sweet as he is fun. During his handling assessment, Flint happily allowed staff to handle his ears, paws, and tail with no concerns. When invited to get rowdy, he simply answered with an adorable play bow. We think it`s safe to say that so far, life to Flint is all about making best friends and sharing the fun.At around 37 pounds, he`s ready to discover what it`s like to have a family of his own, and whoever brings him home won`t just be changing his life. They`ll be gaining a devoted companion who will fill their days with laughter, love, and plenty of happy memories.Flint has been saving all of his love for the person lucky enough to call him theirs. Hopefully, that could be you.

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Mississippi.

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Great Dane puppies and dogs in Mississippi cities

Great Dane Puppies near me Great Dane in Aberdeen Great Dane in Amory Great Dane in Batesville Great Dane in Bay St Louis Great Dane in Biloxi Great Dane in Booneville Great Dane in Brandon Great Dane in Brookhaven Great Dane in Canton Great Dane in Carthage Great Dane in Clarksdale Great Dane in Cleveland Great Dane in Clinton Great Dane in Columbia Great Dane in Columbus Great Dane in Corinth Great Dane in Crystal Springs Great Dane in Diberville Great Dane in Ellisville Great Dane in Flowood Great Dane in Forest Great Dane in Gautier Great Dane in Greenville Great Dane in Greenwood Great Dane in Grenada Great Dane in Gulfport Great Dane in Hattiesburg Great Dane in Hazlehurst Great Dane in Hernando Great Dane in Holly Springs Great Dane in Horn Lake Great Dane in Indianola Great Dane in Jackson Great Dane in Kosciusko Great Dane in Laurel Great Dane in Leland Great Dane in Long Beach Great Dane in Louisville Great Dane in Madison Great Dane in Magee Great Dane in McComb Great Dane in Meridian Great Dane in Moss Point Great Dane in Natchez Great Dane in New Albany Great Dane in Ocean Springs Great Dane in Olive Branch Great Dane in Oxford Great Dane in Pascagoula Great Dane in Pearl Great Dane in Petal Great Dane in Philadelphia Great Dane in Picayune Great Dane in Pontotoc Great Dane in Richland Great Dane in Ridgeland Great Dane in Ripley Great Dane in Senatobia Great Dane in Southaven Great Dane in Starkville Great Dane in Tupelo Great Dane in Vicksburg Great Dane in Waveland Great Dane in Waynesboro Great Dane in West Point Great Dane in Wiggins Great Dane in Winona Great Dane in Yazoo City

Great Dane shelters & rescues in Mississippi

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Mississippi. Browse these Great Dane rescues and shelters below.

Here are a few organizations

Shelter

Humane Society of South Mississippi

2615 25th Ave, Gulfport , MS 39501

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog ?

We've got all the info you need on adopting and caring for a Great Dane puppy . Check out the links below for everything you ever wanted to know about Great Dane puppies and adults .

Great Dane information

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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