Great Dane Adoption in Mississippi: Great Dane Puppies for Sale in Mississippi

Adopt a Great Dane near you in Mississippi

Below are our newest added Great Danes available for adoption in Mississippi. To see more adoptable Great Danes in Mississippi, use the search tool below to enter specific criteria!

Eminem

Great Dane

Male, 3 yrs 6 mos

Gulfport, MS

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

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Shelly

Great Dane/Labrador Retriever

Female, 2 yrs 6 mos

Gulfport, MS

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

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Lexington

Great Dane/Labrador Retriever

Male, Adult

Jackson, MS

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs,

Story

Meet Lexington! If you’ve ever wanted a gentle giant with a soft heart and a handsome grey coat, Lexington is your guy. He is tall, elegant, and full of sweetness — basically the best of both worlds wrapped up in one lovable boy. Lexington is an absolute sweetheart. He loves getting outside to stretch those long legs for walks and playtime, and the best part? He’s easy to walk. No chaos, no drama — just a tall, handsome companion happily strolling by your side. He’s also a smart cookie. Lexington is intelligent, attentive, and highly motivated by treats (especially the good stuff!). He enjoys engaging with his people and would thrive in a home that appreciates both his brains and his big, affectionate heart. Because he’s such a tall boy, Lexington does best with a raised feeder, and his tummy prefers canned food over dry kibble. We’ve learned what keeps him comfortable, and with that simple routine, he does great. Lexington truly shines when he’s with his humans. He bonds deeply and has that soulful, loving presence that big dogs are famous for. The kind that leans into you. The kind that makes you feel chosen. He would do best in a home that can: Appreciate a large-breed companion; Continue giving him structure and guidance; Provide thoughtful introductions to other dogs. Lexington has shown some dog selectivity in the past, so slow, proper introductions are important. With the right setup and leadership, he can absolutely thrive. This sweet, grey gentle giant is ready for a foster or forever home where he can stretch out, enjoy his walks, savor his meals, and most importantly — be loved the way he deserves. If you’ve got room in your heart (and on your couch) for a tall, intelligent, treat-loving sweetheart… Lexington is waiting.May 31, 2026, 11:49 am

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Mississippi.

Great Dane puppies and dogs in Mississippi

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Adopt a Great Dane near you in Mississippi

Below are our newest added Great Danes available for adoption in Mississippi. To see more adoptable Great Danes in Mississippi, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Mississippi cities

Great Dane shelters & rescues in Mississippi

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

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Mississippi

Great Dane puppies and dogs in Mississippi

Jump to:

Adopt a Great Dane near you in Mississippi

Below are our newest added Great Danes available for adoption in Mississippi. To see more adoptable Great Danes in Mississippi, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Mississippi cities

Great Dane shelters & rescues in Mississippi

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics