Mastiff Adoption in Arkansas: Mastiff Puppies for Sale in Arkansas

Adopt a Mastiff near you in Arkansas

Below are our newest added Mastiffs available for adoption in Arkansas. To see more adoptable Mastiffs in Arkansas, use the search tool below to enter specific criteria!

Sherlock Bones

Mastiff/Labrador Retriever

Male, Puppy

Mountain Home, AR

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Story

Hi! I'm Sherlock Bones, the puppy detective of the shelter! Every day, I sniff out fun and mysteries. I'm super friendly and love cuddles. When I'm not playing with my toys, I'm learning new tricks because I'm very smart. I'm also very brave and curious, always ready for a new adventure. If you're looking for a loyal friend who's always ready to play and explore, I'm your pup! Adopt me and let's start our own fun adventures together.May 23, 2026, 6:30 pm

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Fiona

Mastiff/Labrador Retriever

Male, Puppy

Mountain Home, AR

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Story

Hi! I'm Sherlock Bones, a curious and playful pup living in a shelter. Every day is a new adventure as I bravely explore every corner, sniffing out mysteries and making friends. I love to cuddle when I'm tired, but I'm also quite independent, enjoying my own space to dream up new games. Sometimes, I'm a bit shy around new faces, but give me a moment, and I'll be your loyal companion. I'm smart and quick to learn new tricks, always eager to please. If you're looking for a sweet, friendly, and brave friend, I'm ready to solve the greatest mystery of all: finding a forever home where I can share all my love and playful antics!May 23, 2026, 6:30 pm

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Cocoa

Mastiff/Labrador Retriever

Female, Puppy

Mountain Home, AR

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Story

Hi! I'm Cocoa, a sweet, friendly puppy with a curious and brave heart. I love exploring every nook and cranny of my world, and I'm always up for a game or a cuddle. Sometimes, I'm a bit shy, but give me a moment, and I'll be your playful, smart companion. I cherish my independence but being part of a family sounds like the best adventure yet! If you're looking for a loyal friend to share in all of life's big and small moments, I'm right here waiting. Let's start our journey together!May 23, 2026, 6:30 pm

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Bourbon

Mastiff/Boxer

Male, Adult

Mountain View, AR

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

Bourbon jumped into someone's car while they were pumping gas and wouldn't get out. He was friendly but very skinny. The people tried to find his owner, but had no luck. They took him home and learned he is good with other dogs (they have 2) and cats! Bourbon has a very gentle, loving nature. He is also house trained. We don't know much about his past, but we do know he is a huge cuddle bug and will smother you with affection. He will probably follow you are like a shadow. He wants to be as close to people as he can get, often leaning his body against the nearest human. Bourbon is about 2 years old and will weigh around 90 lbs once at a healthy weight. We think he is a Mastiff/Boxer Mix. He is now neutered and fully vaccinated, ready to find his new family. If you would like more information, please contact our shelter at 870-269-5200 or go to our website at schspets.org and complete an adoption application and someone will contact you for a meet and greet. Update: Bourbon just entered the Paws in Prison Program for 8 weeks of training. He will be house trained, leash trained, crate trained and learn many tricks too. He will graduate mid-June and ready for adoption.May 19, 2026, 4:47 pm

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Ralph BW

Mastiff/Mixed Breed (Large)

Male, 1 yr 3 mos

North Little Rock, AR

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Ralph the Derp! Ralph is a huge friendly, enthusiastic, uncoordinated 4-legged energetic goofball! He was rescued from “death row” at a high kill shelter, as a skinny stray with a treatable skin condition. His fur has almost completely grown in & he is now at a healthy weight. This overgrown mastiff/Cane Corso mix pup has no comprehension of his size, leaning into humans for affection or trying to ooze onto laps for cuddles. He is being trained not to jump and not to paw for attention/affection/play because he currently has 85# of mass behind those “congenial” moves. Ralph plays well with dogs of all sizes, but would do best with med-to-larger dogs due to his size & poorly curbed gusto. He hordes toys, taking them all to his chosen dog bed of the day. He likes to carry a special toy “baby” in his mouth when going out in the yard. He does need to be fed in his crate & will guard his empty food bowl from other dogs, unless he is distracted with a toy & led outdoors after meals. He is great on a leash, makes awesome grunty sounds when cuddled, enjoys baths. Ralph will make a great addition to an active family with older children. He is eager to please, food and affection oriented (although a bit stubborn at times), making him an ideal candidate for success with continuation of his training. Please consider adopting the gorgeous big derp into your home. Attributes: In training to avoid jumping/pawing Active family He is neutered, microchipped, had recent cherry eye repair and up to date on all vaccines and preventions. Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)

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Hercules

Mastiff

Male, 6 yrs 10 mos

Heber Springs, AR

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, House-trained,

Story

Hercules is a 74 lb 6-year-old Mastiff mix with a story that will melt your heart. He came to the shelter in rough shape after a life of neglect, but thanks to his resilient spirit, loving care, and medical attention, he's on the mend and blossoming into the happy, handsome boy he was always meant to be. This sweet soul is as gentle as they come. Hercules loves people and soaks up attention like a sponge—his tender heart shines through in every tail wag and soft gaze. Hercules gets along well with other dogs, seems to be potty trained, and is a smart boy who just wants to please. He’s ready to trade his past for a bright, love-filled future. Hercules has waited long enough—he deserves a home that will shower him with the care, comfort, and kindness he’s always deserved. Could that be with you? Apply to adopt Hercules at HeberSpringsHumaneSociety.com Hercules’ adoption fee is $125.00 and includes first vaccinations, worming, microchip, and sterilization. We have a dog park to check compatibility with possible sibling dogs. Please fill out an adoption application at HeberSpringsHumaneSociety.com and a volunteer will contact you in 2-3 business days. The adoption application is NOT on Adopt a Pet and must be completed on the Heber Springs Humane Society website.

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Mastiff puppies and dogs in Arkansas

Jump to:

Adopt a Mastiff near you in Arkansas

Below are our newest added Mastiffs available for adoption in Arkansas. To see more adoptable Mastiffs in Arkansas, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in Arkansas cities

Mastiff shelters & rescues in Arkansas

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog ?

Mastiff information

Mastiff basics