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Mastiff puppies and dogs in Fort Pierce, Florida

Looking for a Mastiff puppy or dog in Fort Pierce, Florida? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Fort Pierce, Florida Other pups in Fort Pierce, Florida Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Fort Pierce, Florida Mastiff shelters and rescues in Fort Pierce, Florida Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Fort Pierce, Florida

These Mastiffs are available in Fort Pierce, Florida.
Photo of Jamison

Jamison

Mastiff

Male, Young
Fort Pierce, FL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Please Call directly For an appointment! 571 NE 44th St.NW corner of Prospect (44th) and 6thOakland Park, FL 33334 Our phone number is 754-223-5378E-mail AnimalAidInc@aol.comJuly 9, 2026, 12:04 am

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Or, how about these Mastiffs in cities near Fort Pierce, Florida

These Mastiffs are available for adoption close to Fort Pierce, Florida.
Photo of Jamison

Jamison

Mastiff

Male, Young
Fort Pierce, FL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Please Call directly For an appointment! 571 NE 44th St.NW corner of Prospect (44th) and 6thOakland Park, FL 33334 Our phone number is 754-223-5378E-mail AnimalAidInc@aol.comJuly 9, 2026, 12:04 am

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Photo of NITA

NITA

Mastiff

Female, 6 yrs 2 mos
Palm City, FL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Nita might be the nicest dog you have ever met. She had a very hard life until she arrives at Nala's new Life Rescue, and she has been with us for over a year now, loving her life in a foster home with lots of dogs, from tiny to big, she loves everyone. She is looking for a good loving family, and she is ready to love you with all she gets. Nita is 5 years old, weighs 65lbs and is up to date on all vaccines, spayed and healthy. We have so much to tell you about her. She currently lives in a foster home with several other dogs, big and small including puppies and she is absolutely wonderful with all of them, Interested, please apply on our website at www.nalasrescue.org. We are located in Palm City, FL

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Photo of Howie

Howie

Mastiff Mixed Breed (Medium)

Male, 8 yrs 10 mos
Sebastian, FL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I’m a big boy with an even bigger heart, ready to be your most loyal companion. I’m the perfect mix of laid-back cuddler and devoted guardian. During overnight stays in a home, I proved to be a wonderful houseguest—fully housebroken, well-mannered, and content relaxing on a comfy dog bed or sleeping at the foot of your bed.I walk beautifully on a leash, take treats gently, know how to sit and give my paw, and love chewies, TV time, and plenty of belly rubs. I enjoy outdoor adventures, but I’m just as happy spending a quiet evening by your side.I’m deeply loyal to my family and can be uncomfortable around strangers, so I’ll do best with an experienced adopter who understands guardian breeds and can provide a calm, structured home. For vet visits and other handling, I’ll need a muzzle and sedative to help keep everyone safe and comfortable.At nearly 100 pounds, I’d love a home with a fenced yard or space to roam. I’m happiest as the only pet, and I do enjoy digging, so a perfectly manicured lawn probably isn’t for me. I also love water, but it’s best if I skip playtime with the hose because I get a little too excited!I know I’m not the right fit for everyone, but if you’re looking for a loyal, loving companion with a big heart, I just might be your perfect match.All of our dogs and cats are spayed/neutered, up to date with age appropriate vaccinations, heart worm or feleuk/FIV tested, fecal tested, rabies and tag, and microchipped before being placed in your home. Our adoption fee helps cover this cost.

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Photo of Oswald 5531

Oswald 5531

Mastiff Mixed Breed (Medium)

Male, 3 yrs 5 mos
Loxahatchee, FL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Oswald, our 3-year-old mastiff mix! This handsome boy came to us ready to find a home with someone who understands his size, strength, and big-hearted personality. Because of his larger build, Oswald will do best with an adopter who is comfortable handling bigger dogs—especially as he continues working on leash skills and learning how to manage his excitement during playtime. He can have bursts of energy, and when he does, he absolutely loves heading outside for games of chase and fetch. The great thing about Oswald is that he knows how to balance his playful side with his calm one. After he’s had his fun, he’s more than happy to settle down beside his person for some quality cuddle time. In fact, his favorite thing in the world might just be a good belly rub! Oswald is currently working on potty training and learning basic commands, but he’s not quite there yet. He’ll need a patient and consistent home that’s willing to continue his training and help him become the best version of himself. With the right guidance and a loving home, Oswald has all the makings of a loyal, fun-loving companion who will bring both energy and affection into your life.

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Photo of Minnie

Minnie

Mastiff Mixed Breed (Medium)

Female, 2 yrs
Loxahatchee, FL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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Photo of Octavia

Octavia

Mixed Breed (Medium) Mastiff

Female, 7 yrs 10 mos
Sebastian, FL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hello, future family! I am a gentle giant with a heart full of love, just waiting for the perfect home to call my own. I absolutely adore my people and enjoy engaging in fun activities that help boost my confidence—things like nose work, agility, and snuffle mats are some of my favorite ways to stay busy and stimulated! I thrive when I have a job to do and would love a family that encourages me to keep learning and growing.While I have never bitten, I do have a strong sense of ownership over my things and am not the best at sharing. Because of this, I would do best in a home with no other pets (although in the right situation, I have gotten along with certain dogs in settings outside the home) and older children (8+) who can respect my boundaries and understand how to manage my "mine" moments.There is one very special thing I will be bringing with me to my forever home: my stainless steel bowl, which has been with me for every moment since I arrived at H.A.L.O. -- "Wilson" never leaves my side!If you're looking for a loyal, loving companion who will bring devotion and joy into your life, I could be the one for you. Will you say yes to me and my Wilson?Requirements: Martingale Collar; Children 8+; No other petsAll of our dogs and cats are spayed/neutered, up to date with age appropriate vaccinations, heart worm or feleuk/FIV tested, fecal tested, rabies and tag, and microchipped before being placed in your home. Our adoption fee helps cover this cost.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Fort Pierce, Florida.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Fort Pierce, Florida

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Mastiff shelters & rescues in Fort Pierce, Florida

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Fort Pierce, Florida. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

12.2 miles

Rescue Adoption, Inc.

3802 Oleander Avenue, Fort Pierce, FL 34982

Pet Types: dogs

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Rescue

18.1 miles

Nala's New Life Rescue Inc

Palm City, FL 34990

Pet Types: cats, dogs

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Rescue

30.5 miles

H.A.L.O. No Kill Rescue

710 Jackson St., Sebastian, FL 32958

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

44 miles

Big Dog Ranch Rescue

14444 Okeechobee Blvd., Loxahatchee, FL 33470

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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