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Mastiff puppies and dogs in Mississippi

Looking for a Mastiff puppy or dog in Mississippi? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in Mississippi Search for a Mastiff puppy or dog Mastiff puppies and dogs in Mississippi cities Mastiff shelters and rescues in Mississippi Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Mississippi

Below are our newest added Mastiffs available for adoption in Mississippi. To see more adoptable Mastiffs in Mississippi, use the search tool below to enter specific criteria!
We'll also keep you updated on Sully's adoption status with email updates.
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Sully

Mastiff/Boxer

Male
Jackson, MS
Size
(when grown) -
Details
-
Story
April 30, 2026, 7:03 pm

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We'll also keep you updated on Slim's adoption status with email updates.
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Slim

Mastiff

Male
Jackson, MS
Size
(when grown) -
Details
-
Story
April 30, 2026, 7:03 pm

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We'll also keep you updated on Presley's adoption status with email updates.
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Presley

Mastiff

Female, Adult
Jackson, MS
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
-
Story
Sweet girl, friendly, playful, even tempered, enjoys being outside, and is ready for her next adventure!April 30, 2026, 7:03 pm

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We'll also keep you updated on Hercules's adoption status with email updates.
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Hercules

Mastiff

Male, Adult
Jackson, MS
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Not good with cats,
Story
Hercules – Small Name? Not a Chance! This Hercules may not wear a cape, but he does have superpowers—like melting hearts with his wiggly tail and lighting up every room with his happy, goofy grin. He’s affectionate, leash-trained, and loves getting out to explore the world by your side. Whether it’s a walk through the neighborhood or just soaking up attention, Hercules is all in. He’s still working on his “hero training” (he’s been known to pull a little Houdini act now and then), so he’ll need a home ready to guide him and keep him safely contained. But with consistency and love, this boy is going to be an absolute superstar. If you’re looking for a loyal sidekick with a big personality and an even bigger heart… Hercules is ready to save the day.April 30, 2026, 7:03 pm

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We'll also keep you updated on Fennel's adoption status with email updates.
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Fennel

Mastiff/Mixed Breed (Medium)

Male, 7 mos
Cleveland, MS
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs,
Story
Apply online at https://www.shelterluv.com/matchme/adopt/CBC/Dog Applying does not commit you to adopting this specific animal. We do not do same-day adoptions without a pre-approved adoption application already on file. Please give us a call for any questions about our adoption process! We are happy to help! Our $70 adoption fee includes spay/neuter prior to adoption, age-appropriate vaccines, deworming, ID tag, heartworm test if over 6 months of age, one week of free Zoom-based dog training through GoodPup, and a microchip. Please do not contact us through Petfinder. Due to the number of inquiries we receive, we recommend contacting us by phone at 662-846-1155 or by email at Jamie.grant@cityofclevelandms.com if you have a specific question about an animal. We will not schedule an adoption until an adopter has filled out an adoption application.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Mississippi.

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Mastiff puppies and dogs in Mississippi cities

Mastiff Puppies near me Mastiff in Aberdeen Mastiff in Amory Mastiff in Batesville Mastiff in Bay St Louis Mastiff in Biloxi Mastiff in Booneville Mastiff in Brandon Mastiff in Brookhaven Mastiff in Canton Mastiff in Carthage Mastiff in Clarksdale Mastiff in Cleveland Mastiff in Clinton Mastiff in Columbia Mastiff in Columbus Mastiff in Corinth Mastiff in Crystal Springs Mastiff in Diberville Mastiff in Ellisville Mastiff in Flowood Mastiff in Forest Mastiff in Gautier Mastiff in Greenville Mastiff in Greenwood Mastiff in Grenada Mastiff in Gulfport Mastiff in Hattiesburg Mastiff in Hazlehurst Mastiff in Hernando Mastiff in Holly Springs Mastiff in Horn Lake Mastiff in Indianola Mastiff in Jackson Mastiff in Kosciusko Mastiff in Laurel Mastiff in Leland Mastiff in Long Beach Mastiff in Louisville Mastiff in Madison Mastiff in Magee Mastiff in McComb Mastiff in Meridian Mastiff in Moss Point Mastiff in Natchez Mastiff in New Albany Mastiff in Ocean Springs Mastiff in Olive Branch Mastiff in Oxford Mastiff in Pascagoula Mastiff in Pearl Mastiff in Petal Mastiff in Philadelphia Mastiff in Picayune Mastiff in Pontotoc Mastiff in Richland Mastiff in Ridgeland Mastiff in Ripley Mastiff in Senatobia Mastiff in Southaven Mastiff in Starkville Mastiff in Tupelo Mastiff in Vicksburg Mastiff in Waveland Mastiff in Waynesboro Mastiff in West Point Mastiff in Wiggins Mastiff in Winona Mastiff in Yazoo City

Mastiff shelters & rescues in Mississippi

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Mississippi. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Animal Rescue Fund of Mississippi

395 W. Mayes St, Jackson , MS 39213

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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