How Do Dog DNA Tests Work?
If you’re curious about your rescue dog’s breed origins or any genetic issues they may have, this one’s for you.
If you’re curious about your rescue dog’s breed origins or any genetic issues they may have, this one’s for you.
by Frances Vega, | September 15, 2025

Oleksii Syrotkin / Stocksy
DNA testing for dogs has become popular in recent years, with many pet parents curious about their dog’s ancestry, health, and behavior. But how do these tests actually work? And are they worth the cost?
Dog DNA tests analyze more than 200,000 genetic markers (SNPs) from cheek swab samples. They use microarray technology, which looks at your dog’s DNA segments against reference databases containing millions of tested dogs over 350 breeds. Laboratories extract DNA from the sample, amplify it, and load it onto specialized chips with fluorescent probes that detect genetic variations. Then they use sophisticated algorithms to calculate breed percentages and identify health risks. If that sounds complicated, it kind of is — but we’re here to help you make sense of it all.
A dog DNA test is a genetic analysis that can tell you more about your pup’s ancestry, breed mix, and even potential health risks. Most tests come as a kit with a cheek swab for collecting a sample at home. After you send this sample back to the lab, scientists extract DNA from the cells and run it through specialized technology that scans for hundreds of thousands of genetic markers.
The results usually reveal your dog’s breed breakdown, which can be especially helpful when they are a mixed-breed or rescue whose background isn’t obvious. Some services likewise provide health screenings, giving you insight into genetic conditions that might affect your pup later in life. This can complement what you already know from your vet, or help you decide on preventive steps, such as spay-neuter timing.
DNA, or deoxyribonucleic acid, carries all the genetic information that makes your dog who they are. By analyzing your dog’s DNA, laboratories can detect inherited traits, estimate breed percentages, and flag genetic mutations linked to certain diseases.
Scientists use something called a microarray chip, which is covered in probes designed to “light up” when they bind with specific DNA sequences. When your dog’s DNA binds to a probe, a machine records it, and software compares those readings to enormous databases of other tested dogs. The more robust the database, the more precise your dog’s results will be.
These insights aren’t just about health. They can explain common behavioral traits, such as why your pup loves tug-of-war or why they’re prone to separation anxiety. They can also give you realistic expectations of exercise needs, grooming, or training — valuable info for any pet parent working on bite inhibition with their puppy.
The accuracy of dog DNA tests varies by testing company and the size of their reference database — but the top services are impressively reliable. Breed results are generally very accurate, particularly when identifying common breeds like Labrador Retrievers, German Shepherds, or popular mixes. Rare breeds or small ancestry percentages may be harder to pinpoint, and false positives can occasionally occur.
Health screenings are also strong, but not perfect. A DNA test can flag risks, but this doesn’t guarantee your dog will develop the condition. That’s why DNA test results should always be discussed with your vet, as with any other medical test.
In short, a DNA test can give you highly useful insights. But it should be viewed as one element in your pet-care tool kit rather than being a crystal ball.
Pet parents choose DNA testing for many reasons, from curiosity to health planning. Here are a few of the top benefits.
DNA tests can flag markers for conditions such as heart disease, vision problems, or hip dysplasia. Knowing this early helps you and your vet create a proactive care plan. It also ties into broader preventive care, including diet, exercise, and spay-neuter considerations.
If your dog is a Husky-Corgi mix, you may already know they’ll need plenty of exercise and mental stimulation. But DNA tests can provide more details, including lifespan expectations as well as genetic tendencies around coat type or weight.
Certain breeds are known for specific behaviors, such as digging, herding, or excessive barking. Understanding these tendencies can help with training, whether it’s teaching your pup not to bark, curbing chewing habits, or managing indoor marking.
Knowing how big your pup will get can make a huge difference when planning your living space, exercise routines, and even which food to buy. DNA tests can give you an estimate, helping you prepare for whether you’ll have a 10-pound lap-dog or a 100-pound jogging buddy.
Prices typically range from $60 to $200, depending how detailed the test is. Basic tests focus on breed, while higher-end options add in health screenings and ancestry reports. If you’re budgeting, keep in mind that this is similar to what you’d spend on preventive care or training essentials.
Yes, in fact, this is one of the main reasons people use DNA testing. These tests can identify dozens of breeds in your dog’s ancestry, even if they’re generations back. That means your scruffy rescue might actually be part medium-sized breed, part toy breed, and part mystery mix.
No, DNA results do not replace vet care and should be seen as supplemental to regular veterinary care. DNA tests are great ways to uncover insights that might otherwise go unnoticed, but your vet should always be the one guiding medical decisions.
Absolutely, if you’re fostering, knowing breed tendencies can help you prepare your home and anticipate behaviors. For adopters, DNA tests can add context to why your pup acts the way they do and how to set them up for success in the long term.
American Kennel Club. “Benefits of Canine DNA Testing.” AKC, 2021. www.akc.org/expert-advice/health/benefits-of-canine-dna-testing.
Boyko, Adam R., et al. “Genomic Analyses of Modern Dog Breeds.” Cell Reports, vol. 19, no. 8, 2017. doi.org/10.1016/j.celrep.2017.05.030.
National Human Genome Research Institute. “What Genetic Testing Can and Can’t Tell You About Your Pet.” NHGRI, 2020. www.genome.gov/about-genomics/fact-sheets/Genetic-Testing-for-Dogs.
New York Times. “How Trustworthy Is Your Dog’s DNA Test?” The New York Times, 27 May 2018. www.nytimes.com/2018/05/27/science/dog-dna-test.html.
Ostrander, Elaine A., et al. “Genetic Testing for Dogs.” Nature Reviews Genetics, vol. 20, 2019. doi.org/10.1038/s41576-018-0086-1.
Parker, Heidi G., et al. “DNA Testing and Domestic Dogs.” Nature Reviews Genetics, vol. 18, no. 12, 2017. doi.org/10.1038/nrg.2017.45

Frances Vega is a Los Angeles/Orange County-based marketer, writer, editor, and partnerships manager.
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