Adopt
Rehome
Menu Hamburger Icon

Great Dane puppies and dogs in Port St Lucie, Florida

Looking for a Great Dane puppy or dog in Port St Lucie, Florida? Adopt a Pet can help you find an adorable Great Dane near you.

Picture of Great Dane

Learn More:

Adopt a Great Dane near you Great Dane in cities near Port St Lucie, Florida Other pups in Port St Lucie, Florida Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Port St Lucie, Florida Great Dane shelters and rescues in Port St Lucie, Florida Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Port St Lucie, Florida

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Port St Lucie, Florida

These Great Danes are available for adoption close to Port St Lucie, Florida.
We'll also keep you updated on Claw's adoption status with email updates.
Needs Home Fast
Photo of Claw

Claw

Great Dane Mixed Breed (Medium)

Male, Adult
Okeechobee, FL
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered, Shots are up-to-date,
Story
-

Learn More

Small right facing arrow
We'll also keep you updated on Zena's adoption status with email updates.
No photo available for Zena

Zena

Great Dane

Female, 1 yr
Jupiter, FL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Zena is a beautiful female puppy. She is very well behaved she is very friendly . Walks good on a leash. Loves to play with toys. She is a big goof ball.

Learn More

Small right facing arrow
We'll also keep you updated on Zena's adoption status with email updates.
No photo available for Zena

Zena

Great Dane

Female, Puppy
Jupiter, FL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Zena is an 11 month old Great Dane puppy she loves everyone dogs,cats,kids. She is a sweet girl has a great personality. Lived with a chihuahua for most of her puppyhood. So she loves small dogs.February 3, 2026, 4:40 pm

Learn More

Small right facing arrow
We'll also keep you updated on Matilda's adoption status with email updates.
Photo of Matilda

Matilda

Great Dane

Female
Jupiter, FL
Size
(when grown) -
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Matilda is a great dane mix she looks and acts just like a dane but a miniature version. She is housebroken very socialized. Great with kids and all dogs. Owner has allergy and couldn't keep her.January 28, 2026, 8:46 pm

Learn More

Small right facing arrow
We'll also keep you updated on Prudence's adoption status with email updates.
Photo of Prudence

Prudence

Great Dane

Female, Puppy
Jupiter, FL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Prudence is 1year old spayed female fawn. She is very people friendly loves everyone. Great with , dogs and kids. She is housebroken walks well on a leash. She loves to go for car rides and walks in the park. She needs an active family she loves to go places.January 9, 2026, 11:15 am

Learn More

Small right facing arrow
We'll also keep you updated on Scarlet's adoption status with email updates.
Photo of Scarlet

Scarlet

Great Dane

Female, 3 yrs
Jupiter, FL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Scarlet is a beautiful fawn female Great Dane. She is very friendly easy going girl. Great with dogs and kids. She walks good on a leash. And has basic training skills.

Learn More

Small right facing arrow

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Port St Lucie, Florida.

    an arrow icon
location arrow icon Current location
  • New York, NY
  • Los Angeles, CA
  • Houston, TX
  • Dallas, TX
  • Brooklyn, NY

Sorry, we can’t find that location! Please try again.

    Age
    an arrow icon

Great Dane puppies and dogs in nearby cities

Great Dane Puppies near me Great Dane in Fort Pierce, FL Great Dane in Jupiter, FL Great Dane in Okeechobee, FL Great Dane in Sebastian, FL Great Dane in Stuart, FL Great Dane in Tequesta, FL Great Dane in Vero Beach, FL

Related breeds in Port St Lucie, Florida

Anatolian Shepherds in Port St Lucie, Florida Bullmastiffs in Port St Lucie, Florida Irish Wolfhounds in Port St Lucie, Florida

Great Dane shelters & rescues in Port St Lucie, Florida

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Port St Lucie, Florida. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Shelter

26.6 miles

Okeechobee County Sheriff's Office Animal Control Services

1480 NW 25th Dr, Okeechobee, FL 34972

Pet Types: cats, dogs

More an arrow icon

Rescue

29.7 miles

Great Dane Rescue of South Florida

Jupiter, FL 33478

Pet Types: dogs

More an arrow icon

Rescue

39.2 miles

Kelly's Fosters

Juno Beach, FL 33408

Pet Types: cats, dogs

More an arrow icon

Rescue

41.4 miles

Big Dog Ranch Rescue

14444 Okeechobee Blvd., Loxahatchee, FL 33470

Pet Types: dogs

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

clipboard with list

Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

Learn More an arrow icon