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Mastiff puppies and dogs in San Antonio, Texas

Looking for a Mastiff puppy or dog in San Antonio, Texas? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in San Antonio, Texas

These Mastiffs are available in San Antonio, Texas.
We'll also keep you updated on Poe's adoption status with email updates.
Photo of Poe

Poe

Mastiff

Male, 3 yrs 5 mos
Kirby, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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We'll also keep you updated on Onyx's adoption status with email updates.
Photo of Onyx

Onyx

Mastiff

Female, 3 mos
Kirby, TX
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Story
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We'll also keep you updated on Old Man's adoption status with email updates.
Photo of Old Man

Old Man

Mastiff Mastiff

Male, Senior
San Antonio, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained,
Story
Old Man is a sweet senior dog who is great with people and kids. He is very loyal and would love to find a warm home where he can enjoy his golden years. I am heartbroken to have to rehome him, but my home was foreclosed on, and I unfortunately no longer have a place to keep him. He deserves a loving family to spend his retirement with.
We'll also keep you updated on Bain (Temporarily)'s adoption status with email updates.
Photo of Bain (Temporarily)

Bain (Temporarily)

Mastiff Mixed Breed (Large)

Male, Puppy
San Antonio, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Shots are up-to-date,
Story
Hi there 👋 I’m a handsome brindle boy who was found near the Eisenhauer Flea Market. I’m safe now, healthy, and hoping my forever family is out there. I’m a big guy—about 85 lbs—and an older puppy. The vet thinks I might be a Mastiff mix. Don’t let my size fool you though; I’m very sweet, loving, and gentle. I have a calm nature, I listen well, and I really enjoy being inside with my people. I’m fully house-trained (no potty accidents here!) and I know how to behave indoors. I’ve been vet-checked, I’m not chipped, and I’m up to date on all my shots—so I’m ready to go home. Because I’m a large boy, I’d do best with a family that’s familiar with big dogs and has the space to give me the love, structure, and stability I deserve. In return, I’ll give you loyalty, affection, and a whole lot of heart. If you think I might be your new best friend—or if you know someone who’s looking—please message my human. I’m ready to find my home 🐾💙
We'll also keep you updated on Goliath's adoption status with email updates.
Photo of Goliath

Goliath

Mastiff

Male, 1 yr 1 mo
San Antonio, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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We'll also keep you updated on BUBBA's adoption status with email updates.
Photo of BUBBA

BUBBA

Mastiff American Bulldog

Male, 3 yrs 1 mo
San Antonio, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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Or, how about these Mastiffs in cities near San Antonio, Texas

These Mastiffs are available for adoption close to San Antonio, Texas.
We'll also keep you updated on Poe's adoption status with email updates.
Photo of Poe

Poe

Mastiff

Male, 3 yrs 5 mos
Kirby, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-
We'll also keep you updated on Onyx's adoption status with email updates.
Photo of Onyx

Onyx

Mastiff

Female, 3 mos
Kirby, TX
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
-
Story
-
We'll also keep you updated on Old Man's adoption status with email updates.
Photo of Old Man

Old Man

Mastiff Mastiff

Male, Senior
San Antonio, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained,
Story
Old Man is a sweet senior dog who is great with people and kids. He is very loyal and would love to find a warm home where he can enjoy his golden years. I am heartbroken to have to rehome him, but my home was foreclosed on, and I unfortunately no longer have a place to keep him. He deserves a loving family to spend his retirement with.
We'll also keep you updated on Bain (Temporarily)'s adoption status with email updates.
Photo of Bain (Temporarily)

Bain (Temporarily)

Mastiff Mixed Breed (Large)

Male, Puppy
San Antonio, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Shots are up-to-date,
Story
Hi there 👋 I’m a handsome brindle boy who was found near the Eisenhauer Flea Market. I’m safe now, healthy, and hoping my forever family is out there. I’m a big guy—about 85 lbs—and an older puppy. The vet thinks I might be a Mastiff mix. Don’t let my size fool you though; I’m very sweet, loving, and gentle. I have a calm nature, I listen well, and I really enjoy being inside with my people. I’m fully house-trained (no potty accidents here!) and I know how to behave indoors. I’ve been vet-checked, I’m not chipped, and I’m up to date on all my shots—so I’m ready to go home. Because I’m a large boy, I’d do best with a family that’s familiar with big dogs and has the space to give me the love, structure, and stability I deserve. In return, I’ll give you loyalty, affection, and a whole lot of heart. If you think I might be your new best friend—or if you know someone who’s looking—please message my human. I’m ready to find my home 🐾💙
We'll also keep you updated on Goliath's adoption status with email updates.
Photo of Goliath

Goliath

Mastiff

Male, 1 yr 1 mo
San Antonio, TX
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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We'll also keep you updated on Luke AG's adoption status with email updates.
Photo of Luke AG

Luke AG

Mastiff American Pit Bull Terrier

Male, 3 yrs 11 mos
Von Ormy, TX
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)

These pups are in San Antonio, Texas too!

Below are our newest added Mastiffs available for adoption in San Antonio, Texas. To see more adoptable Mastiffs in San Antonio, Texas, use the search tool below to enter specific criteria!
We'll also keep you updated on Blackie's adoption status with email updates.
Photo of Blackie

Blackie

Bullmastiff Shepherd (Unknown Type)

Female, Puppy
San Antonio, TX
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
She was born 10-14-2024. We would like for Blackie to go to a family that will love and take care of her. She and her siblings are very protective of their home. Her mother is a Bull Mastiff and had a total of 6 puppies. Unfortunately, we need to put 4 puppies up for adoption by the end of the year or my dad will have to put us down.
We'll also keep you updated on Bashful's adoption status with email updates.
Photo of Bashful

Bashful

Bullmastiff Shepherd (Unknown Type)

Male, Puppy
San Antonio, TX
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
He was born 10-14-2024. We would like for Bashful to go to a family that will love and take care of him. He and his siblings are very protective of their home. His mother is a Bull Mastiff and had a total of 6 puppies. Unfortunately, we need to put 4 puppies up for adoption by the end of the year or my dad will have to put us down.

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in San Antonio, Texas.

Mastiff puppies and dogs in nearby cities

Related breeds in San Antonio, Texas

Mastiff shelters & rescues in San Antonio, Texas

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in San Antonio, Texas. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

7 miles

Bexar County Animal Facility

5510 Duffek Dr, Kirby, TX 78219

Pet Types: cats, dogs

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Shelter

14 miles

Animal Defense League of Texas - Nacogdoches Campus

11300 Nacogdoches Road, San Antonio, TX 78217

Pet Types: cats, dogs

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Rescue

18.5 miles

God's Dogs Rescue TX

Von Ormy, TX 78073

Pet Types: cats, dogs

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Rescue

18.9 miles

San Antonio Pets Alive

4710 Highway 151, Building One, San Antonio, TX 78227

Pet Types: cats, dogs

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Shelter

18.9 miles

San Antonio Animal Care Services

4710 State Highway 151, San Antonio, TX 78227

Pet Types: cats, dogs

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Rescue

27 miles

Lucky's Legacy Rescue - TX Transport Stop

17815 La Cantera Pkwy, San Antonio, TX 78257

Pet Types: cats, dogs, small animals

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Shelter

29.2 miles

City of Lytle Animal Care and Control

17971 W FM 2790 S, Lytle, TX 78052

Pet Types: cats, dogs

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Rescue

36.8 miles

Sunni's Animal Missions

canyon lake, TX 78133

Pet Types: cats, dogs

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Shelter

43.2 miles

San Marcos Regional Animal Shelter

750 River Road, San Marcos, TX 78666

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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