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Mastiff puppies and dogs in Roanoke, Virginia

Looking for a Mastiff puppy or dog in Roanoke, Virginia? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Roanoke, Virginia Other pups in Roanoke, Virginia Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Roanoke, Virginia Mastiff shelters and rescues in Roanoke, Virginia Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Roanoke, Virginia

These Mastiffs are available in Roanoke, Virginia.
We'll also keep you updated on Tanner's adoption status with email updates.
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Tanner

Mastiff Hound (Unknown Type)

Male, 5 yrs
Roanoke, VA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
He was left behind when his owners moved out. Very affectionate.He looks like a goofy, kind of floppy hound dog as he ambles around. He’s sweet and affectionate. Gets along with most dogs. He’s a little bossy with food especially with a timid dog. Feeding in a crate solves that. Loves his play time in the yard with two stout dogs. Great on a leash. The Adoption Fee Includes Age-Appropriate Vaccinations (DA2PPV, Bordetella, Rabies), Deworming, Spay/Neuter, Microchip, Flea, Tick and Heartworm Treatment and Prevention, and Sheltering. Adult Dogs are Heartworm Tested and Treated as Needed. Tanner's adoption fee (if picked up locally in Crossville, Tennessee) is $225. If transport is needed, his adoption fee is $525 (out of state, East Coast, Great Lakes or New England regions).Thank You for Your Interest in Adopting a Canine Companion from Foccas-tn.org!To Apply Please Copy and Paste to Your Browser:https://service.sheltermanager.com/asmservice?account=hb2428&method=online_form_html&formid=41LOCATED IN CROSSVILLE, CUMBERLAND COUNTY, TN. WE CAN TRANSPORT OUT OF STATE, Visit out website for a full list of adoptable pets… https://foccas-tn.org/

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We'll also keep you updated on Summit's adoption status with email updates.
Photo of Summit

Summit

Mastiff American Pit Bull Terrier

Male, Young
Roanoke, VA
Size
(when grown) -
Details
Spayed or Neutered,
Story
Primary Color: Tan Secondary Color: White Weight: 82.5 Age: 1yrs 2mths 0wks

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Or, how about these Mastiffs in cities near Roanoke, Virginia

These Mastiffs are available for adoption close to Roanoke, Virginia.
We'll also keep you updated on Tanner's adoption status with email updates.
Photo of Tanner

Tanner

Mastiff Hound (Unknown Type)

Male, 5 yrs
Roanoke, VA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
He was left behind when his owners moved out. Very affectionate.He looks like a goofy, kind of floppy hound dog as he ambles around. He’s sweet and affectionate. Gets along with most dogs. He’s a little bossy with food especially with a timid dog. Feeding in a crate solves that. Loves his play time in the yard with two stout dogs. Great on a leash. The Adoption Fee Includes Age-Appropriate Vaccinations (DA2PPV, Bordetella, Rabies), Deworming, Spay/Neuter, Microchip, Flea, Tick and Heartworm Treatment and Prevention, and Sheltering. Adult Dogs are Heartworm Tested and Treated as Needed. Tanner's adoption fee (if picked up locally in Crossville, Tennessee) is $225. If transport is needed, his adoption fee is $525 (out of state, East Coast, Great Lakes or New England regions).Thank You for Your Interest in Adopting a Canine Companion from Foccas-tn.org!To Apply Please Copy and Paste to Your Browser:https://service.sheltermanager.com/asmservice?account=hb2428&method=online_form_html&formid=41LOCATED IN CROSSVILLE, CUMBERLAND COUNTY, TN. WE CAN TRANSPORT OUT OF STATE, Visit out website for a full list of adoptable pets… https://foccas-tn.org/

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We'll also keep you updated on Summit's adoption status with email updates.
Photo of Summit

Summit

Mastiff American Pit Bull Terrier

Male, Young
Roanoke, VA
Size
(when grown) -
Details
Spayed or Neutered,
Story
Primary Color: Tan Secondary Color: White Weight: 82.5 Age: 1yrs 2mths 0wks

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We'll also keep you updated on Buck's adoption status with email updates.
Photo of Buck

Buck

Mastiff Hound (Unknown Type)

Male, Young
Union, WV
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
***COURTESY POST*** Approximately 50 pounds (?Boxer/Mastiff?) and one / one and a half years old.  Buck is a neutered male and is up to date on shots.  As you can tell from the photos, Buck is an inside pet.  He is good with other dogs.  Cats are an unknown.  There are two children in the house, ages three & eight years old.  Buck can be “clumsy” around the children but he is good with them.  Buck is in a home with indoor birds and outside quail (does not chase).  He is leash trained but he does pull.  He’ll go into a crate but will “fuss” once there.  Housebroken with a schedule.  He’s a big goof ball.  He likes to cuddle and hug.  Used to being on furniture.  Sleeps in bed with the family.   Family has been displaced from their home and have downsized to a camper.  Buck deserves more space (he could hardly be loved any more).  This is a family pet, sadly, in need of a new home. Please call 304-660-6532 for additional information and/or to discuss adoption arrangements. December 3, 2025, 11:42 am

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Mastiff puppies and dogs in nearby cities

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Mastiff shelters & rescues in Roanoke, Virginia

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Roanoke, Virginia. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

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Focus on Cumberland County Animal Safety - VA transport stop

Roanoke, VA 24001

Pet Types: cats, dogs

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Shelter

2.5 miles

Regional Center for Animal Control & Protection

1510 Baldwin Ave., Roanoke, VA 24012

Pet Types: cats, birds, dogs, farm animals, rabbits, reptiles, small animals

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Rescue

37 miles

Monroe County Animal League

PO Box 343, Union, WV 24983

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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