Mastiff Adoption in Virginia: Mastiff Puppies for Sale in Virginia

Adopt a Mastiff near you in Virginia

Below are our newest added Mastiffs available for adoption in Virginia. To see more adoptable Mastiffs in Virginia, use the search tool below to enter specific criteria!

Bones

Mastiff

Female, 4 yrs

Roanoke, VA

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with dogs, Good with cats, House-trained,

Story

Bones is a big girl with an even bigger heart. Weighing in at around 130 pounds, she may not realize her size—once she trusts you, she’ll happily climb into your lap or wrap you up in a big hug, showering you with sweet chin kisses.She can be shy at first and takes a little time to warm up, but once she does, her affectionate and loyal nature truly shines. Bones is housebroken and well-mannered in the home. She does well around cats, often choosing to ignore them, but she would do best as the only dog so she can soak up all the love and attention she deserves.Loud noises and thunderstorms can be scary for her, so she’ll need a patient, understanding home where she feels safe and secure.Bones is being rehomed through no fault of her own after the passing of her owner. She’s ready to find a loving family who will give her the comfort, stability, and affection she craves Bones' adoption fee is $275.FOCCAS is a foster based, non-profit rescue in Crossville, TN. The adoption fee Includes Age-Appropriate Vaccinations (DA2PPV, Bordetella, Rabies), Deworming, Spay/Neuter, Microchip, Flea/Tick/Heartworm Prevention, and Sheltering. Adult Dogs are Heartworm Tested and Treated as Needed. FOCCAS does not DNA test or guarantee breed. If transport is needed, there are additional fees to cover department of agriculture requirements and transport, the additional fee adds $300 to the adoption fee (any location out of Tennessee, East Coast, Great Lakes or New England regions)Thank You for Your Interest in Adopting a Canine Companion from Foccas-tn.org!To Apply Please Copy and Paste to your browser:https://service.sheltermanager.com/asmservice?account=hb2428&method=online_form_html&formid=41LOCATED IN CROSSVILLE, CUMBERLAND COUNTY, TN. WE CAN TRANSPORT OUT OF STATE, Visit out website for a full list of adoptable pets… https://foccas-tn.org/

Learn More

April

Mastiff

Female, Adult

Covington, VA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

April is a Mastiff mix who is approximately 4 yrs old and weighs just over 90 lbs. Very gentle and sweet. For anyone looking for a dog who embodies fun, friendliness, and a touch of goofiness, April is the perfect match. Her love for life and her sociable spirit make her an ideal companion for those who appreciate a lively and loving pet. With April around, there's never a dull moment, and her presence is sure to bring endless joy to any home. If you are interested, stop in between noon and 4 pm on Tue, Wed, Fri, Sat, Sunday.April 26, 2026, 2:02 pm

Learn More

Grant in Blackstone VA

Mastiff

Male, Adult

Richmond, VA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs,

Story

Location: Blackstone, VAMeet your new best friend, Grant! Grant was found as a stray when he decided to go into a beauty salon. He was sweet and well behaved, just checking things out. Can you blame him? Grant is friendly to all he has met, both two legged and four legged. He is a big boy at 70 pounds, but seems to be calm and gentle like most of his breed. He is believed to be about three years old, so young enough for a lot of fun but old enough to know what it means to be a family member. He would love hanging around the house with you, going for walks on leash or playing games in a fenced in yard. While we have not tested him with children, there aren't any at the pound, they feel confident that he would do well as he is a pretty chill guy This is the perfect time to add a furry friend to your life and Grant would love the job! Please contact Sheila for a meet and greet and to learn more about this fine fella. 434-292-1099 (office) or email at angelwinstonspackrescue@gmail.com. Thank you for helping this most deserving dog.April 28, 2026, 10:28 pm

Learn More

Blaze

Mastiff

Male, Young

Roanoke, VA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

I’m just looking to rehome him. He’s a very good dog. Just not fair to him. I’m struggling to take care of him. He’s friendly great with kids. I just need a place to run and be a dog.

Learn More

Ralph BW

Mastiff/Mixed Breed (Large)

Male, 1 yr 2 mos

Wyethville, VA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Ralph the Derp! Ralph is a huge friendly, enthusiastic, uncoordinated 4-legged energetic goofball! He was rescued from “death row” at a high kill shelter, as a skinny stray with a treatable skin condition. His fur has almost completely grown in & he is now at a healthy weight. This overgrown mastiff/Cane Corso mix pup has no comprehension of his size, leaning into humans for affection or trying to ooze onto laps for cuddles. He is being trained not to jump and not to paw for attention/affection/play because he currently has 85# of mass behind those “congenial” moves. Ralph plays well with dogs of all sizes, but would do best with med-to-larger dogs due to his size & poorly curbed gusto. He hordes toys, taking them all to his chosen dog bed of the day. He likes to carry a special toy “baby” in his mouth when going out in the yard. He does need to be fed in his crate & will guard his empty food bowl from other dogs, unless he is distracted with a toy & led outdoors after meals. He is great on a leash, makes awesome grunty sounds when cuddled, enjoys baths. Ralph will make a great addition to an active family with older children. He is eager to please, food and affection oriented (although a bit stubborn at times), making him an ideal candidate for success with continuation of his training. Please consider adopting the gorgeous big derp into your home. Attributes: In training to avoid jumping/pawing Active family He is neutered, microchipped, had recent cherry eye repair and up to date on all vaccines and preventions. Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)

Learn More

Marty

Mastiff

Male, 2 yrs 4 mos

Winchester, VA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Learn More

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Virginia.

Mastiff puppies and dogs in Virginia

Jump to:

Adopt a Mastiff near you in Virginia

Below are our newest added Mastiffs available for adoption in Virginia. To see more adoptable Mastiffs in Virginia, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in Virginia cities

Mastiff shelters & rescues in Virginia

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog ?

Mastiff information

Mastiff basics

Home

Adopt a Dog

Adopt a Mastiff

Virginia

Mastiff puppies and dogs in Virginia

Jump to:

Adopt a Mastiff near you in Virginia

Below are our newest added Mastiffs available for adoption in Virginia. To see more adoptable Mastiffs in Virginia, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in Virginia cities

Mastiff shelters & rescues in Virginia

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog ?

Mastiff information

Mastiff basics