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Mastiff puppies and dogs in Cheyenne, Wyoming

Looking for a Mastiff puppy or dog in Cheyenne, Wyoming? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Cheyenne, Wyoming Other pups in Cheyenne, Wyoming Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Cheyenne, Wyoming Mastiff shelters and rescues in Cheyenne, Wyoming Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Cheyenne, Wyoming

These Mastiffs are available in Cheyenne, Wyoming.
We'll also keep you updated on Nona's adoption status with email updates.
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Nona

Mastiff St. Bernard

Female, Adult
Cheyenne, WY
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
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Or, how about these Mastiffs in cities near Cheyenne, Wyoming

These Mastiffs are available for adoption close to Cheyenne, Wyoming.
We'll also keep you updated on Nona's adoption status with email updates.
No photo available for Nona

Nona

Mastiff St. Bernard

Female, Adult
Cheyenne, WY
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
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We'll also keep you updated on Harley's adoption status with email updates.
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Harley

Mastiff

Male, 2 yrs
Fort Collins, CO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Big heart, strong stride, and sweetness all the way through — this handsome boy is ready to find his place in the world. He’s a gentle soul who loves other dogs and greets people with warmth and happy energy. The kind of companion who leans in for affection and looks at you like you’re the best part of his day. On leash, his excitement sometimes takes the wheel, and he pulls hard — not out of stubbornness, just pure eagerness to explore everything life has to offer. With a little guidance and consistency, this very good boy is sure to blossom into a wonderful walking partner. If you’re looking for a loyal friend with a big heart, dog-friendly charm, and love to give in abundance, he’s ready to step forward and walk right into your life. 🐾

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We'll also keep you updated on Zeus's adoption status with email updates.
Photo of Zeus

Zeus

Mastiff

Male, Adult
Fort Collins, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered,
Story
Hi, I’m Zeus, a 6-year-old Mastiff–Rottweiler mix weighing in at a totally manageable 103 lbs (even though I firmly believe I’m lap-sized). If you’re looking for world-class cuddles, look no further. I was surrendered to my foster by my family because my parents were getting divorced. Neither could find space for me in their new homes. It's been a hard transition but I'm finally coming out of my shell. I’m sweet, soft-hearted, and full of love, living up to the title of gentle giant. I adore dogs, do great with kids, and I’m totally cool with cats—no chasing, just peaceful coexistence. I’m fully potty trained, walk beautifully on a leash (no pulling here!), and I know my basics commands like sit and drop it. I am a good boy and proud of it. Even though I am 6 at heart, I’m still a big puppy. My determination to catch my own tail and joyful energy is guaranteed to make you laugh even on your worst day. Toys? Oh, I love them… but fair warning: if it squeaks, I will surgically remove the squeaker with my teeth.  A few things I’m working on: I can be shy and bark when people show up unannounced, men especially, but I’m working hard on my confidence. Public outings are helping a lot, and I’m improving every day. I don’t love being alone and would do best with someone who has time for me—or even better, another medium to large dog to keep me company. I’m a bit of a counter surfer and an occasional trash inspector. A locked trash can solves that problem completely. But my foster has yet to find a place high enough on her shelves to keep me from having a second breakfast. I'm clever but not destructive. If you’re looking for a loyal shadow, a cuddle buddy, and a companion who will love you endlessly, I might just be your guy.March 10, 2026, 3:01 pm

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We'll also keep you updated on Ombre's adoption status with email updates.
Photo of Ombre

Ombre

Mastiff Boxer

Male, 4 yrs 3 mos
Fort Collins, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
This pups adoption fee has been partially sponsored by All Aboard or an All Aboard partner! The new adoption fee is reflected on the profile. IMPORTANT NOTE REGARDING THIS DOG: Ombre can be easily startled by new people and things. He is occasionally slower to meeting new people, especially men, and other dogs. Ombre has the potential to get overwhelmed easily and can resource guard. Ombre needs an adopter who is patient and willing to continue his training. Ombre is big guy with a lot of love to give! He came to us with a few quirks that his foster has been helping him work through and he is constantly making progress! He does need an experienced adopter who will be dedicated to continued positive reinforcement training and ongoing socialization. He has come a long way since his arrival in January 2023 and needs the perfect partner in crime to help him continue making progress! Ombre can be a bit skittish with new sounds or unexpected movements and can resource guard at times. He is occasionally slow to warm up to new men and other dogs, but not consistently! He can get overwhelmed in new high-activity environments, so continued socialization is a must. Ombre is very loving and curious, and acts like he is his foster's shadow. This loving boy is a classic case of a dog who is worth the effort! With the right, experienced adopter who is committed to setting him up for success through continued training and socialization, Ombre will absolutely blossom into his adopter's most dedicated friend! He is house and kennel trained. Playgroup - https://youtube.com/shorts/Brmr_wwiRKs ADOPTION FEE: $75 We are a foster-based rescue and do not generally have pups available to meet at our office except during adoption events on Saturdays. Interested in this pup? The first step is to complete our online application by clicking the "Apply for Adoption" button. Please note that we are only able to finalize adoptions at events for approved adopters. The earlier you apply, the better as it takes time to review and approve applications. We host adoption events almost every Saturday from 11:00am to 2:00pm at Petco in Fort Collins (2211 S College Ave. STE 200, Fort Collins, CO 80525)! Check our Instagram and/or Facebook page for info on where we will be hosting adoptions this weekend! All Aboard Animal Rescue saves dogs and puppies from high-kill shelters in other states. These pups are brought to Colorado, where they are required to be spayed or neutered - breaking the cycle of unwanted litters of puppies who end up as strays! Please consider supporting us in this mission by adopting, fostering, volunteering, or donating.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Cheyenne, Wyoming.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Fort Collins, CO Mastiff in Wellington, CO

Related breeds in Cheyenne, Wyoming

Bullmastiffs in Cheyenne, Wyoming Neapolitan Mastiffs in Cheyenne, Wyoming Saint Bernards in Cheyenne, Wyoming

Mastiff shelters & rescues in Cheyenne, Wyoming

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Cheyenne, Wyoming. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

34.3 miles

Until They're Home

Fort Collins, CO 80524

Pet Types: cats, dogs, rabbits, small animals

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Shelter

34.3 miles

Animal Friends Alliance - Taft Hill Campus Adoptions

2200 N Taft Hill Rd., Fort Collins, CO 80524

Pet Types: cats, dogs

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Rescue

41.2 miles

All Aboard Animal Rescue

Fort Collins, CO 80526

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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