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Neapolitan Mastiff puppies and dogs in Frederick, Maryland

Looking for a Neapolitan Mastiff puppy or dog in Frederick, Maryland? Adopt a Pet can help you find an adorable Neapolitan Mastiff near you.

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Adopt a Neapolitan Mastiff near you Neapolitan Mastiff in cities near Frederick, Maryland Other pups in Frederick, Maryland Search for a Neapolitan Mastiff puppy or dog near you Browse Neapolitan Mastiff puppies and dogs in nearby cities Browse related breeds in Frederick, Maryland Neapolitan Mastiff shelters and rescues in Frederick, Maryland Learn more about adopting a Neapolitan Mastiff puppy or dog

Adopt a Neapolitan Mastiff near you in Frederick, Maryland

We don't see any Neapolitan Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Neapolitan Mastiffs in cities near Frederick, Maryland

These Neapolitan Mastiffs are available for adoption close to Frederick, Maryland.
We'll also keep you updated on MOOSE's adoption status with email updates.
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MOOSE

Neapolitan Mastiff Neapolitan Mastiff

Male, 1 yr 10 mos
HAGERSTOWN, MD
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
The most beautiful, stunning, perfectly well behaved gentle giant !! Moose is in doggy daycare and has proven himself a perfect gentleman. He was actually purchased from a breeder as a puppy, and the family has a baby on the way, and do not have the time to commit to moose, which is why they trusted us to find him a wonderful and suitable forever home. He's neutered, UTD on vaccines , microchipped , walks beautifully on leash and eats 8 cups of food a day!

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We'll also keep you updated on MOOSE's adoption status with email updates.
Needs Home Fast
Photo of MOOSE

MOOSE

Neapolitan Mastiff Neapolitan Mastiff

Male, 1 yr 10 mos
Winchester, VA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
The most beautiful, stunning, perfectly well behaved gentle giant !! Moose is in doggy daycare and has proven himself a perfect gentleman. He was actually purchased from a breeder as a puppy, and the family has a baby on the way, and do not have the time to commit to moose, which is why they trusted us to find him a wonderful and suitable forever home. He's neutered, UTD on vaccines , microchipped , walks beautifully on leash and eats 8 cups of food a day!

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These pups are in Frederick, Maryland too!

Below are our newest added Neapolitan Mastiffs available for adoption in Frederick, Maryland. To see more adoptable Neapolitan Mastiffs in Frederick, Maryland, use the search tool below to enter specific criteria!
We'll also keep you updated on BRANDON's adoption status with email updates.
Photo of BRANDON

BRANDON

St. Bernard

Male, 6 yrs 7 mos
Frederick, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered, Shots are up-to-date,
Story
Brandon is a 5 1/2 year old St, Bernard mix. He is a gentle giant. He is a little standoffish when meeting a new person(s). He is very affectionate once he knows you. He loves rubs and scratches. Brandon loves going for walks and checking out the many play yards here at the ranch. He is very mellow. He would thrive in any size family. He follows commands and is eager to please. He loves his treats and is very gentle when taking them. He doesn't like cats. He is one of the sweetest loving dogs. Brandon is eagerly waiting for his forever home. ##1533014##

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We'll also keep you updated on Skye's adoption status with email updates.
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Skye

Great Dane Mixed Breed (Large)

Female, 3 yrs 1 mo
Frederick, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Current Location: Rockville, MD Hello! My name is Skye! I'm coming to OPH on 1/9/2026. Please check back soon for updates on my personality, and to see adorable new photos. I’m looking for my forever family! Is that with you? If so please click “apply for adoption” or submit an application through the Adopt tab. Let’s get our family started!

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We'll also keep you updated on Black Beauty's adoption status with email updates.
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Black Beauty

Great Dane

Male, 2 yrs 1 mo
Frederick, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Current Location: Parsonsburg, MD Meet Black Beauty: A Stunning Great Dane Ready for the Right Match At 95 pounds and 2 years old, this stunning Great Dane is exactly what his name promises: absolutely beautiful. With his sleek black coat and commanding presence, Black Beauty is a head turner who embodies everything magnificent about this gentle giant breed. Black Beauty has a rambunctious play style that's full of energy and enthusiasm. He needs other dogs who are able to read his cues and interact well with his spirited approach to play. The good news? He's lived successfully with several other dogs, kids, and even cats, showing that with the right companions and environment, he can thrive in a multi pet household. This active boy would be best in an environment where he has space to run and play. He needs regular exercise to burn off his energy and keep him happy and balanced. Black Beauty also loves puzzles and things that use his brain power, showing that he's not just physically active but mentally engaged as well. A Great Dane who can think and problem solve is a wonderful companion for someone who enjoys interactive training and enrichment activities. Due to his size and exuberance, Black Beauty would likely do best in a home without small children. His enthusiasm and large frame could be overwhelming for little ones, even though his intentions are purely loving. Black Beauty is waiting for someone who knows and loves the Great Dane breed, someone who understands their unique needs and incredible hearts. He needs a companion and guide who can provide him with structure, exercise, mental stimulation, and the love he deserves. If you're experienced with large breeds and ready for a stunning, intelligent boy who will fill your life with loyalty and companionship, Black Beauty is ready to meet you.

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Search for a Neapolitan Mastiff puppy or dog

Use the search tool below to browse adoptable Neapolitan Mastiff puppies and adults Neapolitan Mastiff in Frederick, Maryland.

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Neapolitan Mastiff puppies and dogs in nearby cities

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Related breeds in Frederick, Maryland

Bullmastiffs in Frederick, Maryland Great Danes in Frederick, Maryland Saint Bernards in Frederick, Maryland

Looking for a specific shelter or rescue?

There are often many great Neapolitan Mastiffs for adoption at local animal shelters or rescues. Click below to find a shelter or rescue in your area!

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Want to learn more about adopting a Neapolitan Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Neapolitan Mastiff puppy. Check out the links below for everything you ever wanted to know about Neapolitan Mastiff puppies and adults.

Neapolitan Mastiff basics

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Where do Neapolitan Mastiffs come from? How many types of Neapolitan Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Neapolitan Mastiff.

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