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Great Dane puppies and dogs in Frederick, Maryland

Looking for a Great Dane puppy or dog in Frederick, Maryland? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Frederick, Maryland

These Great Danes are available in Frederick, Maryland.
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Goliath

Great Dane

Male, 1 yr 6 mos
Frederick, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Goliath-Great Dane male, Brown Merle ~ 18 mo. (Oct. 2026) Contact rescuebc@hotmail.com for an application Goliath came to rescue when his prior owner's health deteriorated to the point of not being able to see to his needs, dementia. Goliath has lived a family life, lived with smaller dogs and is a very good boy. He's a typical Great Dane and will enjoy having a family life again. Goliath's adoption fee is $450 to help cover the medical costs of getting ready for adoption. For our application, please email rescuebc@hotmail.com Please include your location and a phone number for future communication.

Or, how about these Great Danes in cities near Frederick, Maryland

These Great Danes are available for adoption close to Frederick, Maryland.
Photo of Goliath

Goliath

Great Dane

Male, 1 yr 6 mos
Frederick, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Goliath-Great Dane male, Brown Merle ~ 18 mo. (Oct. 2026) Contact rescuebc@hotmail.com for an application Goliath came to rescue when his prior owner's health deteriorated to the point of not being able to see to his needs, dementia. Goliath has lived a family life, lived with smaller dogs and is a very good boy. He's a typical Great Dane and will enjoy having a family life again. Goliath's adoption fee is $450 to help cover the medical costs of getting ready for adoption. For our application, please email rescuebc@hotmail.com Please include your location and a phone number for future communication.
Photo of Dolly

Dolly

Great Dane Labrador Retriever

Female, Adult
Westminster, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.All of the animals posted on our site have been temperament tested. While not all are in the immediate area, once we have processed and approved your application, we will move the dog to our adoptive area for you to meet, greet and hopefully adopt. Sometimes we will have more than one application on a dog. That does not mean it automatically goes to another family but you should be aware of the fact that until you are approved and set up for the meet/greet.. the dog could get adopted by another applicant.Dolly has large Great Dane genes grafted onto a somewhat smaller body. Not that anyone would ever call her small, but you would say she's a manageable size, which is perfect. If you love the Dane look, but aren't sure you could handle a full size model, we have Dolly waiting for you. She is currently only 60 lbs., but that is a bit deceiving, as she is very underweight. We would like to see at least 15 lbs. more on her ribs and we are working on it. She is now getting top quality groceries, something she has never had before. Still a young dog,  she is in the process of learning about how to deal with the world around her and she is learning fast. Her foster has some comments to help you understand this 'dog-in-progress. 'She’s nervous around new people and things. She does warm up after a bit. Her initial reaction to people that she doesn’t know is to low growl. She is trying to tell everyone to give her a moment to process the new information. I don’t recommend a house with cats or small animals. She’ tries to chase down all the birds,  and squirrels when we’re outside. I’m fairly confident her life prior to rescue wasn’t a good one. It's heartbreaking seeing a good dog trying to cope with a world she was never shown. UPDATE:I have had her for a month now, and she is learning! I took her to the vet today, and while she was nervous, she did not growl. So there has been improvement on that aspect. She wasn’t super outgoing and wanting everyone’s attention, so definitely stand by the slower to warm up to strangers. I highly suspect she’s been abused. She is highly intelligent and learns new things really fast.  She really has the potential to be an excellent dog, and wants to be loved and please her person. MORE UPDATE: Since being here at my house over a month now I have some new insights into her. She is not dog friendly with all dogs.  She's OK with my male dog, but not so happy with my female.  I've been working on getting her to ignore people on walks and she's doing better. She doesn't like it if strangers get too close when we are out.  In the yard. she's definitely going to need at least a 6 foot fence to keep her safely secured.  I will say, she is house trained and does let you know when she needs to go out. She also does very well in her kennel. She is very smart, and can learn things pretty quickly. She has all her shots and is ready and waiting for the person or family who like bigger dogs, but aren't ready for an actual Goliath. Dolly is a good girl! She is hoping you will want to help her be a good dog and come for her soon.   If you are interested in Dolly, please fill out an application at: https://reachoutrescue.rescuegroups.org/forms/form?formid=4588    Or contact: rorrcanine@gmail.com   *** Click here to sponsor this dog! ***Visit this organization's web site to see any additional information available about this pet.October 31, 2026, 12:12 am
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ROO

Great Dane

Female, Adult
Hagerstown, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered, Shots are up-to-date,
Story
  Roo is a 2–3 year old Blue Merle Great Dane adult who weighs 85 pounds and was found abandoned by a well-known lake in Tennessee.  Someone rescued her from this terrible fate of no food or clean water and no place to be as she was wandering around the lake area very skinny and starved.  She was so grateful when someone took her home.  She then had different people foster her only for a few days at a time until this wonderful family saw her plight and need and said.....let us take her and foster her with a good rescue group.  Now this big girl named Roo has some stability in her life and has earned the nickname “Velcro dog.”  Of course this lost and abandoned girl who was deserted by a lake and then bounced a few times, wants to be right by your side and soak up every ounce of love and attention you’re willing to give her.  She will learn one day that noone is ever going to abandon her again.  This athletic girl has plenty of energy, loves to play with a happy spirit and and is an impressive olympic class jumper. She will thrive best in an active home.  Food definitely motivates her and this makes it super easy to train her and get her undivided attention. Roo is house-trained, crate-trained, cat-friendly, and absolutely loves to snuggle in the bed with her humans.    Roo bonds quickly and becomes very protective of her people so we will have tips on how to temper that zealous enthusiasm to claim you. She needs a family where she can be the queen of the castle and receive endless love and attention in return. If you’re looking for a loyal companion who will stick by you through everything, Roo is your girl!       Please write to Critter Cavalry Rescue at ccrtennessee@gmail.com if you are interested.  She is currently fostered in Tennessee and can be adopted locally and also can transport to a loving family that is northeast of Tennessee.  We transport almost weekly on the weekends.       PLEASE NOTE:  Our dogs are transported from Tennessee to meeting places in the states where we have posted.  Further information about us is given on our Adopt-A-Pet site.  The adoption fees vary and will be provided as well as noted on the application you receive.  Contact us at 615-661-5333 or ccrnewengland@gmail.comNovember 3, 2026, 6:38 pm
Bonded Pair
Photo of Cleopatra

Cleopatra

Great Dane English Mastiff

Female, 1 yr 9 mos
Hagerstown, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Shots are up-to-date,
Story
Sweet and affectionate girl who thrives with her brother Wreckx or solo. Up to date with vaccines and preventatives. Crate trained.
Photo of Ghost

Ghost

Great Dane

Male, 1 yr
HAGERSTOWN, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Ghost! Ghost is a gentle, shy neutered male, about 1 to 2 years old, a merle Great Dane of about 60 pounds, who is looking for a patient person to show him what home is all about. He was part of a large Frenchie hoarding case, and he spent a couple of months roaming neighborhoods on his own before he came into care. He has been vetted and is ready for the next chapter of his life. Ghost is very fearful and was semi-feral when he came to us, so he's still learning how to trust. He's a bundle of nerves, but there's a sweet dog under it all. On a leash, he's a star. He'll stay glued to your hip and walk like a pro. He doesn't seem to mind other animals, and he's gentle by nature. Without a leash and a job to do, Ghost can seem unsure how to just be a dog, and he'll need help learning to relax, play, and explore. A foster home noted that he guarded his food, so he'd do best with a quiet routine and his own space at mealtimes. The basics - Age: About 1 to 2 years - Sex: Male, neutered - Breed: Merle Great Dane - Weight: About 60 pounds - Vetted: Yes - Leash manners: Excellent - Other animals: Doesn't seem to mind them - Food: Has guarded his food, so feed him separately - Temperament: Very fearful, gentle His perfect home: a patient, experienced adopter with a calm household, who understands fearful dogs and is happy to move at Ghost's pace. A confident, easygoing resident dog could help him, and a fenced yard would be a plus. If you've loved a shy dog before, Ghost needs you. Apply to meet him today!
Photo of Journey

Journey

Great Dane Catahoula Leopard Dog

Female, 1 yr 6 mos
Hagerstown, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
Meet Journey 🐾 Journey is a beautiful, affectionate girl with a fun loving personality and a heart full of loyalty. She’s the perfect mix of playful and loving, always ready for an adventure but just as happy soaking up attention from her people. She’s friendly, outgoing, and gets along wonderfully with other dogs. Journey also absolutely adores children and would make an amazing family companion. Whether it’s a walk, a car ride, or just hanging out at home, Journey is happiest when she’s included. She’s athletic, curious, and loves to explore, making her a great match for an active home. Journey is crate trained, house trained, rides well in the car, and walks nicely on a leash. She’s got a solid foundation and is ready to settle right into her forever home. With her sweet nature and easygoing personality, she’s the kind of dog who fits in just about anywhere. If you’re looking for a loyal companion who’s equal parts fun and affection, Journey is ready to start her next chapter with you. Journey’s adoption fee is $300 which includes spay, age appropriate vaccines, parasite prevention, and microchip. Apply to adopt at www.fullcirclerescueandsanctuary.com

These pups are in Frederick, Maryland too!

Below are our newest added Great Danes available for adoption in Frederick, Maryland. To see more adoptable Great Danes in Frederick, Maryland, use the search tool below to enter specific criteria!
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Jackson

Bullmastiff Boxer

Male, 2 yrs 6 mos
Frederick, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Currently fostered in: Brooklyn Park, MD 💙Meet Jackson!💙 This big, goofy teddy bear adores people, has personality for days, and has one of the sweetest hearts you'll ever meet! At 2.5 years old and about 75 pounds, Jackson firmly believes he is the perfect size to be your personal shadow, weighted blanket, emotional support buddy, and full-time best friend. He takes the title 'sidekick' very seriously. Privacy? Never met her. Getting up to grab a snack? He's coming with you (and wants one too!) Going to run errands? He's at the door ready to go! Need to use the bathroom? Well... Jackson believes that's a team activity too. This all means one thing: Once Jackson bonds with you- you've got the most loyal best friend for life. 💙ENERGY AND PERSONALITY💙 Jackson is everything we love about big dogs— equal parts sweetheart and goofball! He charms everyone he meets, and is sure to make you laugh with his oversized puppy antics and his determination to convince you that he is lap-dog sized. He adores meeting new people, listens well, and has a happy-go-lucky outlook on life that makes everyone fall in love with him. Jackson also loves toys, bones, car rides, naps in his humans bed, and is 100% convinced that every snack in your hand was probably meant for him. (Honestly...he makes a really compelling argument.) Jackson has a balanced energy level and is happy to lounge around OR go on an adventure. He has recently been to birthday parties, yoga classes, the beach, etc. and had a blast everywhere he went! He doesn't care where you're going- he's just so grateful he gets to go with you! 💙SOCIAL LIFE💙 Jackson is known to quickly win hearts wherever he goes. He gets along very well with other dogs of all sizes, though his play style is best described as "VERY enthusiastic." He'd love a larger canine friend who enjoys roughhousing as much as he does or a canine companion who doesn't mind his goofy antics. He'd also be perfectly happy soaking up all of your attention as an only dog. Jackson currently lives in a foster home with two cats and bounces between polite curiosity and chasing them in an effort to get them to play with him. 💙IDEAL HOME ENVIRONMENT💙 Like many rescue dogs, Jackson is still learning that being alone isn't so scary and that his humans will always be back for him. He would do best in a home where someone is home often, or where they can make arrangements for him to spend the day with someone while they are at work (i.e.: doggie daycare, hanging out with a family member/friend/sitter, etc.) After spending so much of his life without a family of his own, Jackson's hoping for a home that understands he's still healing from his rough start, will be patient as he continues to build confidence, and won't mind having a devoted sidekick who thinks life is better together. Jackson has brought so much joy to his foster home, so we know he will bring a ton of joy to your home too! At the end of the day, Jackson is just a big sweet softie that has waited far too long for a furever family that shows him endless love and safety. Jackson has spent long enough wondering when it will finally be his turn. If you're looking for a dog who will love you with his whole entire heart every single day for the rest of his life... Jackson has been waiting his whole life for you. 💙INCLUDED VETERINARY CARE💙 Jackson is up to date on vaccinations, neutered, microchipped, and receiving heartworm, flea, and tick preventatives along with routine parasite treatments and yearly routine heartworm/lyme testing.
Photo of Maggie

Maggie

Anatolian Shepherd Mixed Breed (Medium)

Female, 3 yrs 5 mos
Frederick, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
Location: Herdon, VA Maggie is an incredibly smart, lively girl who is always ready for her next adventure. She loves people and thrives on human companionship. While she may take a few minutes to warm up to someone new, once she does, she’s all about snuggles, pets, and plenty of sweet kisses. This girl is eager to learn, making her a great candidate for continued training. She is already crate trained, potty trained, and walks well on a leash, giving her a strong foundation for success in her forever home. She is great with other dogs after a short introduction! Maggie loves to run, play, and stay active. Whether she’s zooming around the yard, exploring on walks, or engaging her brain with training and enrichment activities, she’s happiest when she has an outlet for her energy and intelligence. On the other hand, she also loves to lay at your feet and relax while you watch a movie with the family! Maggie could excel as a working dog, farm dog, or active companion for someone looking for a partner in adventure. After a few weeks, she could even settle into a typical 9-5 routine. She loves her crate and is extremely quiet, too, making her the ideal candidate for any type of abode! If you’re looking for a smart, fun, and loving dog to share life’s adventures with, Maggie may be the perfect match!

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Frederick, Maryland.

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Related breeds in Frederick, Maryland

Great Dane shelters & rescues in Frederick, Maryland

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Frederick, Maryland. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

8.1 miles

Bourbon County Rescue

1275 W Patrick Street, Frederick, MD 21702

Pet Types: cats, dogs, rabbits, small animals

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Rescue

22.5 miles

Critter Cavalry Rescue - MD

Hagerstown, MD 21746

Pet Types: dogs

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Rescue

22.6 miles

Reach Out Rescue & Resources

P. O. Box 542, Westminster, MD 21158

Pet Types: cats, dogs

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Rescue

25.4 miles

RRARS

Hagerstown, MD 21740

Pet Types: dogs

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Rescue

25.4 miles

Blues City Animal Rescue - HAGERSTOWN MD Transport stop

HAGERSTOWN, MD 21740

Pet Types: dogs

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Rescue

25.4 miles

Full Circle Rescue & Sanctuary - Maryland Transport Stop

Hagerstown, MD 21740

Pet Types: cats, dogs

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Rescue

25.6 miles

WTFarm Rescue - Hagerstown, MD - Transport

Hagerstown, MD 21742

Pet Types: cats, dogs, farm animals, horses

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Rescue

27.5 miles

A Home of Their Own Animal Rescue

Silver Spring, MD 20906

Pet Types: cats, dogs

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Rescue

31.8 miles

Traveling Tails Dog Rescue - Round Hill, VA

Round Hill, VA 20141

Pet Types: dogs

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Rescue

33.6 miles

Mid-Atlantic Great Dane Rescue, West Virginia Chapter (6)

N/A, Martinsburg, WV 25404

Pet Types: dogs

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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