Adopt

Great Dane puppies and dogs in Greenville, Illinois

Looking for a Great Dane puppy or dog in Greenville, Illinois? Adopt a Pet can help you find an adorable Great Dane near you.

Picture of Great Dane

Adopt a Great Dane near you in Greenville, Illinois

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Greenville, Illinois

These Great Danes are available for adoption close to Greenville, Illinois.
Photo of Smokey

Smokey

Great Dane

Female, Young
Belleville, IL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Not good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Approx DOB January 2025. We adopted Smokey 6/13/2026, after she had spent six weeks with her breeders mom, as her original family could no longer handle her. She's very sweet, sometimes goofy, and mostly a couch potato. She does have bursts energy, and needs a good walk or two a day, or a few sessions playing in the backyard. We have a 5 YO Dane female, altered, and a 4 YO Dane male, unaltered; we've had them both since 8 weeks. They got along well for 7 weeks, until Smokey had issue w/our girl - big fight. Now both won't have anything to do with her; we have to keep them separated 24/7, which isn't good for anyone in the house. She bonded with me (mom) instantly. Think part of the aggression toward our girl was resource guarding me, and trying to become the dominant one. She became more comfortable with us over the weeks (good!) - more tail wagging, better appetite; perhaps trying to solidify her position here. She'll make a WONDERFUL only dog.
Photo of Tippi

Tippi

Great Dane Labrador Retriever

Female, Adult
Godfrey, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered, Shots are up-to-date,
Story
Hope Rescues is all volunteer, all visits must be scheduled you may do that by filling out an online application as that is needed for a visit. You can find an application our website. Our adoption fee is $275.00 which includes Rabies vaccine, spay/neuter, current heart worm test, DHPP booster, Bordetella vaccine, Microchip, Worming.Tippi Est DOB 4/3/2022 Female Lab Mix Tippi is a sweet girl who came from a bad place. Because of the past, she is unsure of strangers. But once she knows she can trust you, she is a wonderful girl. She would need a home without kids. She does ok with some dogs but not sure about cats. She is crate trained and is doing very well with learning manners.Please help us make room to save more homeless pets!!! Adopting from Hope Rescues saves the life of two.. the one you adopt and the one your adoption makes room for. We are a Rescue which means we physically go and save lives. Hope pulls animals on their last day of life from animal control facilities that still use the inhumane gas chamber to put to death homeless pets. Please visit our website at www.hoperescues.orgMarch 10, 2026, 7:29 am
Photo of Poppy

Poppy

Labrador Retriever Great Dane

Female, Young
Belleville, IL
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Poppy is about 2.5-3 years old. She loves to go on lots of walks and learn new tricks. She knows sit, wait, shake, leave it, drop it, touch, kennel, and hush. She is a ball of energy and would love a home with someone willing to give her the outdoor time and physical attention she thrives on. She can get very excited and zooms around new people but normally settles down after getting acclimated.
Photo of Dainty

Dainty

Cane Corso Great Dane

Female, 3 yrs
East ST Louis, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
Meet Dainty! She is new to our rescue and looking for a family to call her own! If you are interested in a meet and greet for adoption for Dainty, please fill out an application on our website at www.gatewaypets.org/adopt. If you are interested in learning more about Dainty or the adoption process at GPG, please email placement@gatewaypets.org All of our dogs and cats will be microchipped, spayed or neutered, and up-to-date on vaccinations at the time of adoption. For more photos of Dainty, follow us on Facebook Gateway Pet Guardians and Instagram @gatewaypets ... #gpgDainty. To view other adoptable pets from our shelter, please visit, www.gatewaypets.org/adopt. Gateway Pet Guardians is proud to offer a variety of mixed breed dogs available for adoption. However, please keep in mind that we rarely know the genetic background of the animals we rescue and, as such, we cannot guarantee the exact breed combinations found within this dog. Therefore, we do not know his/her actual genetic makeup. Just know that this dog is probably a variety of several different breeds that have combined to create one very amazing and unique animal.

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Greenville, Illinois.

Great Dane puppies and dogs in nearby cities

Related breeds in Greenville, Illinois

Great Dane shelters & rescues in Greenville, Illinois

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Greenville, Illinois. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

43.8 miles

Hope Animal Rescues

PO Box 397, Godfrey, IL 62035

Pet Types: dogs

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

clipboard with list

Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

Learn More an arrow icon