Great Dane Adoption in O Fallon, IL: Great Dane Puppies for Sale in O Fallon, IL

Adopt a Great Dane near you in O Fallon, Illinois

These Great Danes are available in O Fallon, Illinois.

Smokey

Great Dane

Female, Young

Belleville, IL

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Not good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Approx DOB January 2025. We adopted Smokey 6/13/2026, after she had spent six weeks with her breeders mom, as her original family could no longer handle her. She's very sweet, sometimes goofy, and mostly a couch potato. She does have bursts energy, and needs a good walk or two a day, or a few sessions playing in the backyard. We have a 5 YO Dane female, altered, and a 4 YO Dane male, unaltered; we've had them both since 8 weeks. They got along well for 7 weeks, until Smokey had issue w/our girl - big fight. Now both won't have anything to do with her; we have to keep them separated 24/7, which isn't good for anyone in the house. She bonded with me (mom) instantly. Think part of the aggression toward our girl was resource guarding me, and trying to become the dominant one. She became more comfortable with us over the weeks (good!) - more tail wagging, better appetite; perhaps trying to solidify her position here. She'll make a WONDERFUL only dog.

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Or, how about these Great Danes in cities near O Fallon, Illinois

These Great Danes are available for adoption close to O Fallon, Illinois.

Smokey

Great Dane

Female, Young

Belleville, IL

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Not good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

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Special Needs

Ben

Great Dane

Male, Senior

Collinsville, IL

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Needs special attention, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Ben is a 140-pound gentle giant who will turn 9 in August. He is a loving, affectionate, people-oriented dog who thrives on companionship and being part of a family. I adopted him when he was about one year old, and he has spent nearly seven years with my family, growing up alongside two older large-breed dogs, including a Great Dane to whom he was especially attached. Over the past two years, both of his longtime canine companions passed away due to old age. After the loss of his closest companion, his behavior changed, and he began excessive licking and grooming that resulted in an open wound on his right hind leg. The wound has been difficult to heal because he continues to lick the area when unsupervised. Ben is not being rehomed because of aggression or behavioral problems. He would do best in a home with more companionship, attention and ideally other friendly dogs. He will come with his favorite futon mattress and toys. Ben is due for his annual vaccinations and rabies booster.

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Tippi

Great Dane Labrador Retriever

Female, Adult

Godfrey, IL

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered, Shots are up-to-date,

Story

Hope Rescues is all volunteer, all visits must be scheduled you may do that by filling out an online application as that is needed for a visit. You can find an application our website. Our adoption fee is $275.00 which includes Rabies vaccine, spay/neuter, current heart worm test, DHPP booster, Bordetella vaccine, Microchip, Worming.Tippi Est DOB 4/3/2022 Female Lab Mix Tippi is a sweet girl who came from a bad place. Because of the past, she is unsure of strangers. But once she knows she can trust you, she is a wonderful girl. She would need a home without kids. She does ok with some dogs but not sure about cats. She is crate trained and is doing very well with learning manners.Please help us make room to save more homeless pets!!! Adopting from Hope Rescues saves the life of two.. the one you adopt and the one your adoption makes room for. We are a Rescue which means we physically go and save lives. Hope pulls animals on their last day of life from animal control facilities that still use the inhumane gas chamber to put to death homeless pets. Please visit our website at www.hoperescues.orgMarch 10, 2026, 7:29 am

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Violet

Great Dane

Female, Adult

St. Louis, MO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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Yogi

Great Dane Mixed Breed (Large)

Male, 1 yr 7 mos

Pacific, MO

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Spayed or Neutered,

Story

Meet Yogi 🐾 Yogi is a 1-year-old high energy boy with the biggest heart 🤎 He loves attention, playing, and being close to his people at all times. He does great with bigger kids and would thrive with an active family who can match his energy and give him lots of love. He can get a little anxious when away from his people because he bonds deeply and always wants to be part of the action. Yogi also has no idea how big he is, so expect lots of oversized cuddles, leaning on you, and goofy moments 😂 He’s still young, playful, and learning, but he’s incredibly loving and loyal. Yogi is looking for a forever home filled with patience, affection, and plenty of belly rubs and he’ll love his people with his whole heart in return.

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Gunner

Labrador Retriever Great Dane

Male, 10 mos

St. Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

PLEASE NOTE! WE ARE A TEXAS BASED RESCUE. THIS DOG IS CURRENTLY IN TEXAS AND WILL BE TRANSPORTED TO YOUR STATE ONCE ADOPTED. Our app can be found at haydudeequine.org Hi there! I'm Gunner. I'm an 10-month-old pup weighing about 60 pounds, and I'm looking for a family who appreciates a dog with a big heart and an even bigger personality. I've been told I'm quite the conversationalist. Now, don't worry—I'm not a nonstop barker. I just like to share my thoughts. If you're talking, I'll probably have something to say about it. If dinner is running late, expect a few comments. If we're headed out on an adventure, you'll definitely hear my excitement. Some people call it sass; I call it excellent communication skills. When I'm not busy chatting, you'll probably find me in the water. I absolutely LOVE to swim, splash, and play. A pond, pool, creek, lake, sprinkler—if it's wet, I'm interested. Water is my happy place, and I'd love a family who enjoys outdoor adventures as much as I do. I'm a sweet, social guy who enjoys making new friends and being part of the action. At 60 pounds, I'm a sturdy pup, but I'm still young and excited to learn new things. Whether we're exploring the great outdoors, going for a walk, or relaxing at home, I'll be right by your side—offering companionship, loyalty, and the occasional opinion. If you're looking for a friendly, water-loving best friend who will keep you laughing and always be ready for the next adventure, I might be the perfect match. Hope to meet you soon! Love, Gunner

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Great Dane puppies and dogs in O Fallon, Illinois

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Adopt a Great Dane near you in O Fallon, Illinois

These Great Danes are available in O Fallon, Illinois.

Or, how about these Great Danes in cities near O Fallon, Illinois

These Great Danes are available for adoption close to O Fallon, Illinois.

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in nearby cities

Related breeds in O Fallon, Illinois

Great Dane shelters & rescues in O Fallon, Illinois

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog?

Great Dane basics

Great Dane basics