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Great Dane puppies and dogs in Greenville, South Carolina

Looking for a Great Dane puppy or dog in Greenville, South Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Greenville, South Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Greenville, South Carolina

These Great Danes are available for adoption close to Greenville, South Carolina.
Photo of Nixxie

Nixxie

Great Dane

Female, 2 yrs 2 mos
Williamston, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
What are you waiting for? Apply today! Click here to apply for the pet Meet Nixxie, the gentle giant who's ready to steal your heart! 💘 At just 2 years old , this beautiful Fawn Great Dane has all the big puppy loves and leans ♥ She is a owner surrender to due to health reason. Nixxie is the definition of sweet as sugar!. She is a big, cuddly bundle of joy who gets along fabulously with other dogs. She loves to run and play with her new friends on the farm 🌟 Nixxie’s is new to our rescue and settling in great If you would like to meet this sweet girl and make her a part of you family please contact us at Always Room For one More Rescue Williamston SC 🤗 Nixxie has her bags packed and she is ready to make your life complete✨ Nixxie is waiting for the perfect family or solo best friend! Please contact us today. Our adoption process is simple and our fee's are minimal to make the adoption process smooth and stress free so we can help more pups just like Nixxie find forever loving homes. What are you waiting for? Apply today! Click here to apply for the pet
Photo of Hemi

Hemi

Great Dane

Male, 7 yrs 2 mos
Williamston, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
What are you waiting for? Apply today! Click here to apply for the pet Meet Hemi, a Harlequin Great Dane with a massive frame and a gentle heart. At 7 years old, Hemi's world is calm and steady—he's past the wild puppy phase, but his spirit is still willing and affectionate. Rescued underweight but already house trained and now on the mend, he's had a bit of a tough road but hasn't lost his trust in people. Hemi gets along well with other dogs, and his friendly nature shows through in relaxed tail wags and a fondness for leaning into whoever is close by. He's a quiet presence in the house, happy to stretch out and watch the world go by, and just as content to share the couch with anyone who sits down next to him. With his size and calm nature, he's looking for a home that can appreciate the small routines and big cuddles he loves. Your new best friend is just one click away. What are you waiting for? Apply today! Click here to apply for the pet
Photo of Rella

Rella

Great Dane

Female, 3 yrs 2 mos
Williamston, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
What are you waiting for? Apply today! Click here to apply for the pet Meet Cinderella, a lovely 2-year-old female Great Dane who is ready to step into her forever home! 🌟🐾 Cinderella aka Rella was found as a stray and taken to a local shelter where we pulled her from. Rella has a tough fight she was severley emaciated after a slow refeed and lots of love Rella's personality has blossomed into a affection searching confident little lady.Rella is a staff favorite here at the rescue She has came a long way and is now ready for the next chapter full of love and devotion never to have to be alone hungry nor scared ever again Rella has a true Cinderella story she is just waiting to be someone's little princess👑 Rella loves her stuffies <3 If you would like to meet Rella please contact us at Always Room For One More Williamston SC 💖 Our Adoption process is simple and adoption fee's are minimal. Remember, you can meet Cinderella in person to see if she’s the one for you! Times are very flexible to Meet this sweet girl. Let’s make her next chapter the best one yet. Every animal deserves a happy ending. This one starts with you. 🐶 What are you waiting for? Apply today! Click here to apply for the pet
Photo of Jake

Jake

Great Dane

Male, 7 yrs 2 mos
Williamston, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
What are you waiting for? Apply today! Click here to apply for the pet Jake is a fawn Great Dane living and at seven years old, he’s got the gentle, thoughtful temperament that comes with age. He arrived as an owner surrender and has been working on putting weight back on, but even now he carries himself with dignity. His size is commanding, but there’s nothing pushy or overwhelming about him. Jake moves with surprising calm, settles quickly, and seems content just being near people. While he appreciates time outdoors, Jake truly wants a quieter home environment where he can relax and soak up attention. He responds well to steady routines and, like most Great Danes, values a soft spot to nap. Jake would fit best with adopters who love cuddling and playing outdoors. What are you waiting for? Apply today! Click here to apply for the pet
Photo of Brynn

Brynn

Great Dane

Female, 2 mos
Williamston, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
What are you waiting for? Apply today! Click here to apply for the pet Brynn is a brindle Great Dane with a striking, and playful presence. She’s house trained and already spayed. Despite having been underweight on arrival, she’s warming up quickly and showing her gentle side every day. Brynn gets along well with other dogs and children, making her a good fit for a wide range of family situations. She’ll thrive in a home that gives her enough room to stretch out and relax, and she’s looking for someone who appreciates both her size and her easy-going, friendly personality. Her playful spirit is grounded by her calm demeanor—a combination that’s hard to find. Ready to meet your new best friend? Apply now! What are you waiting for? Apply today! Click here to apply for the pet
Photo of Pippin (Courtesy Post)

Pippin (Courtesy Post)

Great Dane American Pit Bull Terrier

Male, 4 yrs 5 mos
Rutherfordton, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
This is a courtesy post. Please do not contact Heart of the Foothills for information. Please email the owner at meganmaglione@yahoo.com(704) 619-3895.He is a 4 year old Great Dane mix. He is neutered and 55-60lbs. Up to date on all shots/vaccines. He is playful, loves attention, does well with walks/exercise. He does well with other dogsPlease email meganmaglione@yahoo.com

These pups are in Greenville, South Carolina too!

Below are our newest added Great Danes available for adoption in Greenville, South Carolina. To see more adoptable Great Danes in Greenville, South Carolina, use the search tool below to enter specific criteria!
Photo of Hattie - PLEASE READ ALL INFORMATION

Hattie - PLEASE READ ALL INFORMATION

Anatolian Shepherd

Female, 1 yr 10 mos
Greenville, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
**It is very important to reserach the breed if you are not familiar with them, as livestock guardians have their own set of idiosyncracies that need to be considered. Reminder: Anatolians are NOT German Shepherds, but instead are a very different breed. SOCIAL MEDIA HASHTAG:  #hattietheanatolianshepherd AGE:  1.5yrsWEIGHT: 90-100lbsWORKING LGD:  NODOGS:  GoodDOG RESTRICTIONS:  NO same sized femalesCATS:  Unknown but may be too playful for themCHILDREN: Uncertain but may unintentionally knock down small childrenOTHER ANIMALS:  Unknown (birds, chickens, livestock, exotics, etc)FENCED YARD REQUIRED:  YesGOOD OFF LEASH: NO - ROAMER/RUNNERGROOMING/SHEDDING NEEDS:  HighMEDICAL ISSUES:  NoneMEDICATIONS:  Anti-anxiety medsSPECIAL NEEDS:  Can clear fences so can't be left alone outside; can break out of cratesANXIETY:  Some separation anxiety; combination of medication and canine friends helps significantly.BARKING:  HighEXPERIENCED OWNER NEEDED: YesCRATE TRAINED:  No - breaks out; makes anxiousHOUSE TRAINED:  Not completely; needs continued work but is almost there!GOOD IN CAR:  Yes; can get excited sometimesFUN FACTS:  Hattie is the girl that everyone loves, stealing the show wherever she goes. She's a big hit with everyone and she, in return, adores all. She can sometimes get too excited and hug with enthusiasm, but we're working on that because she's a big girl who is still growing. Hattie loves dogs and would be very lonely and more anxious without them. She has a heart of gold and really cares about her people and friends, sticking by your side as you go through your daily adventures. Hattie enjoys hugs, gives very gentle kisses and takes her treats/meds gently, as well..to boot, she's an excellent alarm clock, so you'll never oversleep! She loves to play and run around the yard with her best buds, tongue hanging out and incredibly happy; a playful buddy would make her very happy, for she would be very sad as an only dog.  **It is very important to research the Anatolian Shepherd breed if you are not very familiar with them, as they are not a breed for everyone. While Hattie is a lovely, gentle, happy girl, the breed does have it's own idiosyncracies that need to be understood and considered, such as running, roaming, barking, and other animals.***Hattie will need to be surpervised while outdoors during the transition to her new home. She will also need to continue house training and her anti-anxiety meds, to which she has responded very well. She is a strong girl, so her new family must be comfortable with this. A 6ft fence is required, and she can never be trusted off leash, even for short distances. ##2355048##
Special Needs
Photo of Theo - PLEASE READ ALL INFORMATION

Theo - PLEASE READ ALL INFORMATION

Anatolian Shepherd

Male, 5 yrs 6 mos
Greenville, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Needs special attention, Spayed or Neutered, Shots are up-to-date,
Story
AGE: Approx 4yrsWEIGHT: 120lbsWORKING LGD:  NO - family pet only DOGS:  GoodDOG RESTRICTIONS:  NO Large or XL males CATS:  UnknownCHILDREN: UnknownOTHER ANIMALS (birds, farm animals, etc): Unknown FENCED YARD REQUIRED:  Yes - 6ft GOOD OFF LEASH:  No - ROAMER/RUNNER GROOMING/SHEDDING NEEDS:  HighMEDICAL ISSUES: Was a light heartworm positive but has been treated and now heartworm negative. MEDICATIONS: Anxiety meds for separation anxiety SPECIAL NEEDS: Severely abused. Will require patience, compassion, and committment. Zero aggression - A very kind dog but terribly afraid of people and tries to get away. ANXIETY:  Very afraid of people and will run and/or hide. Afraid of storms but just wants to be with you.BARKING:  High - Extremely LOUD EXPERIENCED OWNER NEEDED:  Yes CRATE TRAINED:  Yes but will break out HOUSE TRAINED:  Yes GOOD IN CAR:  Yes. Afraid. FUN FACTS: Theo was severely abused. Upon entry into rescue he hid in a corner, his back to us, and shook hard. He's come a long way, however, and does well meeting people, but he is slow to approach. He has developed separtion anxiety and is currently taking medication for that so he doesn't get into anything while nobody is home - otherwise he's extremely well behaved. He loves his people very much, and is devoted. Due to his fears, however, especially with changes into a new home, he will require commitment, devotion, compassion, and patience. He will not be a dog that is snuggly and kissy or wrapped up in his new family, due to his need to learn to trust. He will take a significant amount of time to learn and to establish acceptance of his new life, but he is SO worth it. Theo is a VERY KIND and GENTLE dog with a soft, loving heart. He has absolutely ZERO aggression. He's also highly intelligent. He requires a 6ft fence for playtime and to be on a leash at ALL times when not in the fenced area due to his fears and his breed - NO EXCEPTIONS. He will also need someone who can handle his strength for times when he might be afraid on a leash. Theo loves his canine companions and would be unhappy in a home without other dogs, but he will need gentle introductions b/c he'll be afraid. No dominant males, please. He loves to play and highly depends on his canine friends. Theo LOVES treats and food, and he is very mild mannered when taking them from you. He loves his morning and evening treat and runs to the kitchen and sits handsomely when he knows it's time. He's a fun boy with a tremendous smile, and he also talks to you at times. Theo is devoted to those he loves and appreciates their kindness. He is a lovely boy with an innocent and very sweet disposition. ##1311506##

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Great Dane shelters & rescues in Greenville, South Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Greenville, South Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

17 miles

Always Room For One More

Williamston, SC 29697

Pet Types: dogs

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Rescue

44.1 miles

Heart of the Foothills Animal Rescue

380 US HWY 221 N, Rutherfordton, NC 28139

Pet Types: cats, dogs

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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