Great Dane Adoption in South Carolina: Great Dane Puppies for Sale in South Carolina

Adopt a Great Dane near you in South Carolina

Below are our newest added Great Danes available for adoption in South Carolina. To see more adoptable Great Danes in South Carolina, use the search tool below to enter specific criteria!

Budley

Great Dane/Mixed Breed (Medium)

Male, 3 yrs

Greenville, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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04087B Skadi (Scotty)

Great Dane

Female, 2 yrs

Moncks Corner, SC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

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88624a Muffin - Adoption Amba

Great Dane

Male, 9 mos

North Charleston, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Muffin is in the Adoption Ambassador Foster Program. Foster families take dogs that are available for adoption into their homes and help them get adopted. This is what his foster is saying about him: Meet Muffin! If you are looking for a professional snuggle buddy, then Muffin is the perfect one for you! While he loves taking a good nap, he is a pro at play time! All he needs is a good stick of any size to have a good time! But he will never say no to a delicious treat or a squeaky toy! Muffin loves people and things of all sizes, and he will make sure to tell everyone! Except he does not like anything that makes a loud noise inside the house (vacuum cleaner, hair dryer, etc) but with a little bit of love he will give them a chance! If you offer up a car ride to him, he will not say no and will be your passenger prince! He is a gentle giant with a big heart, loud voice, and is so excited to go to his forever home!Interested in Muffin?! Contact Senior Director of Adoptions, Courtney Gumienny, cgumienny@charlestonanimalsociety.org or 843-329-1577.

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Espresso Martini

Great Dane

Female, 1 yr 1 mo

Chester, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained,

Story

Meet Espresso Martini, the fabulous one-year-old Great Dane who is ready to bring a splash of joy into your life! This lovely lady weighs in at a solid 112 pounds of pure love and affection. Just imagine those big, gentle paws and soulful eyes gazing up at you, ready to share a snuggle or two! 🐾💖 Espresso Martini is not just a pretty face; she’s a smart cookie who’s eager to please! With her training already underway, she’s learning leash manners and is both house and crate trained. That’s right, this girl is a fast learner, and she’s ready to impress you! Plus, she gets along wonderfully with other dogs and children, making her the perfect addition to any family. Just picture all the joyful moments you’ll share together! 🐶✨ And here's a little fun fact: Great Danes are known for their gentle demeanor, often earning them the title of "gentle giants." Espresso Martini embodies this beautifully! 🖤 So, if you’re looking for a big-hearted companion who loves to snuggle and play, Espresso Martini is your girl. Want to be a part of her incredible journey? Every animal deserves a happy ending, and this one starts with you! Espresso Martini is waiting for you to come meet her! Apply for the pet here: https://tinyurl.com/3u7r9sh7

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Rosa

Great Dane

Female, 1 yr

Columbia, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Hi, my name is Rosanna, and I’m a sweet, affectionate girl who’s been learning all about life inside a home for the past couple of weeks.I absolutely love relaxing on the couch, especially if cuddling is involved. When I’m not napping, I enjoy learning how to walk nicely on a leash, hanging out with other animals, and supervising the yard. I take my job as neighborhood squirrel announcer very seriously and will happily let you know when one is nearby.I’m still working on my house training and crate training, but I’m trying my best and improving every day. I walk on a leash, enjoy meeting other dogs, and I’m friendly with new people. I get excited easily, especially outside, but I also have a calm, thoughtful side — sometimes I’ll just sit and watch the world go by.One of my cutest traits is my dramatic apology routine. When I’m corrected, I’ll gently place my head on your foot as if to say, “I’m sorry, please forgive me.” It works every time.I don’t tear up toys or household items, I enjoy structured mealtimes, and I’m eager to keep learning with a patient, loving family. If you’re looking for a cuddly couch companion with a little personality and a lot of heart, I might be the girl for you.My adoption fee includes up-to-date vaccinations, dewormer, and heartworm/flea prevention. Plus, a microchip that is already registered to you! What more could you ask for?If you`d like to meet me, please fill out an application on our website, PawmettoLifeline.org.Adoptions are by appointment Tuesday through Thursday. On Fridays and Saturdays, you’re welcome to walk in anytime between 10:00am and 5:00pm. Please note that we’re closed for adoptions on Sundays and Mondays

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Athena

Great Dane/Mixed Breed (Medium)

Female, 7 mos

Union, SC

Size

(when grown) -

Details

Story

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in South Carolina.

Great Dane puppies and dogs in South Carolina

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Adopt a Great Dane near you in South Carolina

Below are our newest added Great Danes available for adoption in South Carolina. To see more adoptable Great Danes in South Carolina, use the search tool below to enter specific criteria!

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Great Dane puppies and dogs in South Carolina

Jump to:

Adopt a Great Dane near you in South Carolina

Below are our newest added Great Danes available for adoption in South Carolina. To see more adoptable Great Danes in South Carolina, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in South Carolina cities

Great Dane shelters & rescues in South Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics