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Great Dane puppies and dogs in Mauldin, South Carolina

Looking for a Great Dane puppy or dog in Mauldin, South Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Mauldin, South Carolina

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Or, how about these Great Danes in cities near Mauldin, South Carolina

These Great Danes are available for adoption close to Mauldin, South Carolina.
We'll also keep you updated on Cleopatra's adoption status with email updates.
Photo of Cleopatra

Cleopatra

Great Dane

Female, Adult
Travelers Rest, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hello this is so hard to do but I think it’s in the best interest of Cleopatra who is a sweet lap dog girl who I think needs a quieter more predictable environment, where she can be the baby that she is. I feel bad that she is living with us when she is clearly not comfortable. We adopted her at 2 years old and she has always had a skittish nature but she has gotten progressively less tolerant of living with our other animals and is very jumpy and nervous to the point where it can start conflict. I hope to find her a better fit before something happens that i can not fix. If you have the space for this timid beauty please consider reaching out. I’d like to see her happy and relaxed.
We'll also keep you updated on Groot's adoption status with email updates.
Photo of Groot

Groot

Great Dane

Male, Young
Spartanburg, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Groot: ✔️Lovable ✔️Funny ✔️Good snuggler ✔️Plays fetch ✔️Likes to meet new people ✔️Smushy face ✔️Gets along with most other dogs ✔️Silly ears ✔️80 pounds ✔️Guaranteed to make you laugh Housebroken, crate-trained, up to date on shots, and neutered. Born in November, 2019.
We'll also keep you updated on Scooby's adoption status with email updates.
Photo of Scooby

Scooby

Great Dane

Male, Adult
Ware Shoals, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter,
Story
Scooby is a little over three years old. He’s is very sweet and loving. He has loads of energy and loves to run and play with other dogs. He is however food aggressive with other dogs. Other than that he does great with all other animals. He needs a loving home with somebody who can get him out and exercise him regularly as needed.
We'll also keep you updated on Buddy Apr 25's adoption status with email updates.
Photo of Buddy Apr 25

Buddy Apr 25

Great Dane Poodle (Standard)

Male, Adult
Spartanburg, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs,
Story
Thank you for your interest in dog who needs a new home.  Adoption can be one of the most fulfilling experiences in your life and especially in the life of your new canine companion. A note to those looking at CPR.  We have no perfect dogs - but many of our dogs have proven to be perfect for a certain someone.  Our job is to find those someone's.  Our most successful adopters come to CPR not because they want a dog.  They come to us because they want to give a dog a home.  We urge all of our potential adopters not to fall in love with a picture.  While we like to know what you like in looks, a dog is more than a pretty face.  Our goal is to match you with the best possible pet for you and your home.  We want to create furever families.  Our descriptions contain all that we know about this dog today.  We'll update as more information is known.  Are you looking to adopt within the next 30 days?  If so please visit our webpage at www.carolinapoodlerescue.org and complete the application.  You'll find it in the menu on the left hand side.  You'll also find a total listing of all our dogs available.  Just browsing but interested in poodles and poodle mixes?  Please drop a note to applications@carolinapoodlerescue.org with your name, address and phone # and email.  We'll add you to our mailing list. thanks the CPR Adoption team   Date into Rescue: 12/11/2019 born into rescues, returned 04/25/25 when his owner passed away Reason for being in rescue: Buddy (AKASlick) was born into our rescue when his mom and dad were lovingly surrendered by their owners. He was returned nearly six years later when his human passed away. Foster location: Dreamweaver Farms, Pacolet, SC Special Needs? Buddy is neutered, up to date on vaccines and heartworm negative. He arrived back in rescue with a severe bacterial infection deep in his ear. This has been treated. Full medical records will be provided to his new family. Weight:  90 lbs Height: 30 in Spayed/Neutered: Yes Adoption Fee: $299 Fence needed? Buddy is a big boy but he's also a couch potato.  He would be just as happy wiht leash walks (he loves his leash) and as long as your space is big enough to accommodate his majestic size, he will be happy.  Buddy's big need is for you.   What Kind of Home Would Be Best for Me? Buddy is a big dog who lives life on his terms. He’s used to being by his human’s side, so he’ll gladly go wherever you go — whether it’s a hike in the woods, a walk on the beach, or a trip to the grocery store. He rides well in the car and enjoys jamming out to Aerosmith and Dokken (yes, he has great taste in music!). And yes, he’s always down for a pup cup stop!  However, don't leave him alone and walk away.  He wants to go in everywhere with you.   True to the Great Dane nature, Buddy isn't an overly active dog. He needs regular, consistent walks but isn't a marathon or sprint sort of boy.  He needs a good place to do his business, meander some and smell the roses and then he wants to be right back with you.   Buddy has always been an only dog.  He has acclimated well into his foster home with multiple dogs of all sizes but he longs for a human all his own.  Sometimes, he goes and sits in his bed just to get some peace and quiet.  Other times, he's right in the middle of everything.   Buddy "talks."  He is very vocal but not in a big, barky dog kind of way but in a gentle, here is what I am thinking manner.  He will arrggww and ohhhhwoo if he likes what your doing (see below info on his favorite place to be scratched.)  He will grumble and mumble under his breath if he does not like what you are doing.  99 percent of what he does not like is having his ears messed with.  With that big, lovable head, it's the first thing that people go for and I really want to find a leash that says in bright yellow (NOT THE EARS - DON'T TOUCH THE EARS).  Once you know what cues he's sending out, he's so very grateful that you understand him and he does the Dane Lean into you to show his appreciation.  He may not like his head scratched (and that may change if his ears feel better) but he LOVES a good butt scratch.  Right there at the base of the tail, that's his favorite sweet spot!   We do not think Buddy would do well with kids.  He has never been around kids.  His owner was already an empty nester when she adopted Buddy as her new baby when he was just a baby so kids were never around him.  Buddy is an adult's dog.  He longs for that one-on-one relationship he had with his previous owner.  Buddy is loyal and looking for a best friend. What is my personality like? Meet Buddy — a big boy looking for a second chance at a loving home. Buddy was originally adopted from us nearly six years ago, but he was returned after the heartbreaking loss of his beloved human. Buddy may have been born here but he went to a cozy home when he was just a baby so the farm is not familiar. He’s used to being with his person all the time — sharing the couch, sleeping in the bed, and being a constant companion. He has a heart as loyal and big as his 90 pound body. His previous owner loved him dearly, with her family members describing Buddy as a “big old baby” who loves to give kisses and cuddles. Sadly, they were unable to keep him when his human passed, but they knew the kindest thing to do was return him to us so he could find a new loving home. Buddy hopes to hit the jackpot again — to find another human who will love and spoil him just like his first did. Buddy is smart! He’s completed training and proudly comes with a "degree" from his trainer. He knows commands like sit, stay, and shake (with either paw!). He’s eager to please and loves learning new tricks, especially if treats are involved. He was a little overweight — the result of being loved a little more than exercised — but after a few months here at the farm he's down to a svelte 90 lbs and that looks good on hime.  His white muzzle may make him look older, but he’s not even six yet and still full of youthful energy. How do I act when I first meet new people? Buddy loves everyone he meets. He’s a big cuddle bug who will happily snuggle up on the couch or in bed with you, just like he did with his first human. Other tips and tidbits: Buddy's birthday is 12/11/2019. Special note - one of the most heart breaking things about Dane's and standard poodles is the condition known as gastric torsion and torsion (bloat).  Buddy bloated in November of 2025 and very luckily, a young caregiver recognized the signs and alerted the staff so we could get Buddy to a surgeon to save his life.  Buddy survived and now his stomach is "tacked" so he can never, very have a flipped stomach again.   House trained? Buddy is well house trained.  Once he gets on a good schedule, you don't have to worry about accidents in the house.  He is also crate trained although since going home with our director after bloat surgery, he has decided couches and dog beds are better than crates.  Always remember that a dog house trained in my home may not be in yours. We will help you teach your new dog this necessary skill and based on your schedule. Please note - we do not ship dogs.  If you are interested in adopting, please take a look at the distance between the foster home location and your location and make sure you are willing to make that trip.  Most of our dogs are at our farm in Pacolet, South Carolina.   To apply, please visit our webpage at www.carolinapoodlerescue.org and visit the tab on the left that directions you to the online application. Please note that when screening applications, we look at the entire home and then make suggestions based on what would be a good fit for your home.   You are not being screened for a specific dog although we are looking to see what type of dog interests you - poodles or non poodles, color, age, etc.  Others here may be a better fit for you.  It is very difficult to get to know a living animal from a picture and a short description.  Since we are constantly getting in new dogs, this may be a  dog not in our listings yet.  We want you to be very happy with your new companion and will make suggestions based on what you tell us about you. Thank you for considering CPR. November 25, 2025, 8:58 pm

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Great Dane shelters & rescues in Mauldin, South Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Mauldin, South Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

25.9 miles

Critter Connection

PO Box 6886, Spartanburg, SC 29304

Pet Types: cats, dogs

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Rescue

32.1 miles

Carolina Poodle Rescue

Spartanburg, NC 29372

Pet Types: cats, dogs

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Great Dane basics

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