Mastiff Adoption in Dover, DE: Mastiff Puppies for Sale in Dover, DE

Adopt a Mastiff near you in Dover, Delaware

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Dover, Delaware

These Mastiffs are available for adoption close to Dover, Delaware.

Reeses

Mastiff

Female, 5 yrs 4 mos

Queenstown, MD

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Meet Reeses!At just 5 years young and 84 pounds, this beautiful girl is truly one of a kind. And trust us… once you get to know her, you’ll see exactly why she’s so special. Reese’s has the perfect mix of fun and affection—she knows how to play and keep you laughing, but she’s just as happy soaking up all the love and attention she can get.She’s been patiently waiting for someone who understands her and is willing to give her the chance she deserves. The kind of bond you build with Reese’s? Totally worth the wait.Looking for a loyal companion, a goofy best friend, and a whole lot of love? Reese’s is your girl.Come meet her and see for yourself—you might just fall in love.Adoption Application: https://qacmd.seamlessdocs.com/f/adoptionapp (external site)

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Stewie (fka Marmaduke)

Mastiff

Male, 3 yrs 9 mos

Wilmington, DE

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

This friend has just arrived because their owner could no longer keep them. While owners can provide some history on their pets, our medical and behavioral teams will still evaluate them. Dogs that have lived in homes previously typically have some training established, but we cannot guarantee that those behaviors will remain consistent in a new home environment. They are pending interactions with other animals at the shelter until they have been cleared by our vet. Our staff will spend some time getting to know them and we will update their bio with more information as we learn. If you are interested in adopting this dog, please submit an adoption questionnaire! Our adoption process is on a first-come, best-match basis and we are not able to hold animals. If you are interested in this specific dog but it ends up not being the best fit upon meeting, our adoption counselors will work with you to help find a match! All household members, including children and other dogs, must come along for the meeting to make sure it's a good fit. If a match is made, we encourage same-day adoptions! Our adoption fees include the animals' spay/neuter, microchip, age-appropriate vaccinations and preventatives, fecal testing, heartworm testing, and a small bag of food to get you started.

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Daffodil

Mastiff Labrador Retriever

Female, 1 yr

Clayton, NJ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Daffodil 's Story Meet Daffodil, a sweet one-year-old Lab/Mastiff mix who has been waiting patiently at the shelter since March 1, 2026. When Daffodil first arrived, she was shy and unsure of her new surroundings, but with time, patience, and love, she has truly blossomed into a happy and social girl. Now affectionately known as “Daf,” this beautiful pup has become quite the social butterfly. She absolutely loves other dogs and would thrive in a home with a canine companion to help continue building her confidence and keep her company. Daffodil also adores people and enjoys soaking up attention from everyone she meets. Daf walks nicely on a leash and is always eager to get outside and explore. She has done an amazing job coming out of her shell and is more than ready to trade shelter life for a loving forever home where she can continue to flourish. If you’re looking for a gentle, affectionate companion with a playful social side, Daffodil may be the perfect match for you. Please apply for Daffodil at https://www.gloucestercountynj.gov/FormCenter/Animal-Shelter-5/PreAdoption-Application-50

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Enzo

Mastiff Mixed Breed (Medium)

Male, 1 yr 5 mos

Wenonah, NJ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

2 year old boy looking forward to a new forever family. Good with dogs. ##2721137##

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Coco

Mastiff

Female, 5 yrs 4 mos

Blackwood, NJ

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

This big, thick momma is 113 pounds of pure chunky love! Coco has spent much of her life living outside, and now she’s finally getting her chance to enjoy the comfort, safety, and warmth of a real home.Don’t let her size fool you — beneath those extra rolls is the sweetest soul. Coco is gentle, loving, and just wants a soft spot to lay her head and someone to call her own. After everything she’s been through, she deserves a cozy couch, full belly, and a family who will spoil her the way she should’ve been all along.If you’ve got room in your heart (and on your sofa!) for this over-sized sweetheart, Coco is ready to be your loyal, chunky best friend.

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Mastiff puppies and dogs in Dover, Delaware

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Adopt a Mastiff near you in Dover, Delaware

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Dover, Delaware

These Mastiffs are available for adoption close to Dover, Delaware.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Dover, Delaware

Mastiff shelters & rescues in Dover, Delaware

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics