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Mastiff puppies and dogs in Middletown, Delaware

Looking for a Mastiff puppy or dog in Middletown, Delaware? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Middletown, Delaware

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Or, how about these Mastiffs in cities near Middletown, Delaware

These Mastiffs are available for adoption close to Middletown, Delaware.
Photo of Pawla

Pawla

Mastiff

Female, 1 yr 1 mo
Media, PA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
❤️Pawla wants to grant your Monday wish for pure joy! Pawla needs a foster or a foster to adopt! ❤️She’s ready to bring all the love, head tilts, and magical cuddles to her forever family. 🌟 Visit our website to submit anapplication! Www.hindeanimalrescueteam.org
Photo of Enzo

Enzo

Mastiff Mixed Breed (Medium)

Male, 1 yr 10 mos
Wenonah, NJ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Large boy with a lot of love to give. Requires large breed experience, preferably Mastiff and/or Cane Corso experience! Was given to DBU after his parents lost their home and couldn't keep him. Applicants must be over the age of 25 and a homeowner. Renters who have landlord permission and stable track record are also accepted on a case-by-case basis. Meets between current dogs and prospective puppies would occur in Southern New Jersey. Young puppies are prefered to go to homes with another dog for socialization purposes (determined on a case by case basis). The application process includes a deed check, vet check and a virtual home inspection.  Adopting is an incredibly rewarding, challenging, exciting experience and lifelong commitment. Please fill out an application to start your journey to find your perfect pup. *Info & Application: www.dontbullyus.com  ##2721137##
Photo of Bruce

Bruce

Mastiff

Male, Young
Drexel Hill, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Bruce the loveable giant. This big baby is house trained and walks well on a leash. He loves kids and gets along well with other dogs. He will be 4yrs old in April. He has a superb gentle nature and is deeply loyal to his humans. Hes very playful but loves a good sleep on his bed. He was fixed in spring 2026 and received shots at that time as well.
Photo of Cosmo

Cosmo

Mastiff

Female, Puppy
Exton, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Please take the time to research the breed before considering fostering/adoption. Because of their immense size, strength, and strong guardian instincts, they are generally not recommended for first-time or novice owners. They require experienced handling, early socialization, and ongoing training throughout their lives. Meet Cosmo...an Independent Spirit, Born Guardian Personality: Cosmo is a spirited, adventurous, intelligent Caucasian Shepherd puppy with a big personality and natural guardian instincts. She absolutely loves having an older sister and brother! She has already learned so much from watching them, including manners and how to look after and protect the herd. She is observant, confident, curious, and always ready for her next adventure. This is a working guardian breed, and her protective instincts are already beginning to develop. She needs a family who understands that these traits are part of who she is and is prepared to guide them through consistent training, structure, and responsible socialization. Cosmo is also very independent and already shows the self-assured nature of her breed. She likes to explore, observe, and figure things out for herself. She isn't just looking for someone to entertain her—she has a mind of her own and natural instincts that will need to be guided by someone who understands guardian breeds. Her independence is part of what makes her special, but it also means she'll need a patient, confident owner who can provide consistent boundaries without expecting a people-pleasing dog. Favorite Activities: Running, exploring, playing, and going on wild adventures ALL DAY LONG! Cosmo loves having room to roam, following the animals, observing her surroundings, and learning from the older dogs. She enjoys being involved in everything happening around the homestead and is happiest when she has space to explore and a job to do. She is an energetic puppy who needs plenty of room, stimulation, and appropriate outlets for her natural instincts. A small yard or city lifestyle would not be a good fit for her. Medical Issues: No known medical issues reported at this time. What would be the best kind of home: Cosmo needs an experienced, committed home that understands and respects the Caucasian Shepherd breed. A rural property, farm, or homestead with substantial, secure fencing and plenty of room to roam would be ideal. She is accustomed to being around animals and developing her natural livestock guardian instincts, so a home that understands working guardian dogs would be best. She would benefit from having confident, well-mannered canine companions who can help show her the ropes, although any resident dogs must be a good match for her as she matures. Her new family must be prepared to provide consistent boundaries, structured training, early and ongoing socialization, and responsible management of her developing protective instincts. Food is a serious business for Cosmo! She has already shown resource-guarding tendencies, so her adopters must understand resource guarding and be willing to manage it safely and work on it through appropriate, positive training. She needs careful management around food and other valuable resources, not punishment or confrontational attempts to take things away. Cosmo is adorable, playful, and full of adventure, but she is also growing into a powerful guardian breed with strong instincts. She is not a fit for an apartment, a small city yard, or a home unfamiliar with large livestock guardian breeds. She needs space, knowledgeable handling, and a family willing to help her grow into a confident, stable, well-managed adult dog.Click here to watch a video of Cosmo.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  October 21, 2026, 6:10 pm
Photo of Norma

Norma

Mastiff

Female, Young
Exton, PA
Size
(when grown) -
Details
House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Meet Norma - The Sweetheart With a Good Heart   If Norma were a person, everyone would say she has a beautiful, good heart — and they would be right.   Norma is a quiet, laid-back lady who would make the perfect couch potato or lap dog. Her ideal day? A cozy spot on the couch, a soft place to snooze, and her favorite people nearby. She's a true gem out and about: Car rides: Rides like a pro Vet visits: Well-behaved and polite Meeting people: Great with new friends Leash walks: Walks fairly well, just needs a little help with pulling Smart girl: Learned the dog door on her own, always potties outside, figured out how to go up and down steps, and knows "sit" — especially when treats are involved! She’s a good eater and very food motivated, so training is fun. Norma can be guarded when meeting other dogs, so she’ll do best with slow introductions and a patient family who lets her go at her own pace.   Above all else, Norma is just very sweet. She’s gentle, easygoing, and full of quiet love. If you’re looking for a calm companion to share your couch, your car rides, and your heart — Norma is ready. Could Norma be your new best friend? Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  October 21, 2026, 6:10 pm
Photo of Gemma *Courtesy Listing*

Gemma *Courtesy Listing*

English Mastiff

Female, Adult
Exton, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Meet Gemma - 4 year old English Mastiff. The Professional Couch Potato! If you're looking for a laid-back, lovable, 100+ pound lap dog, Gemma is your girl Gemma is the definition of chill. Her favorite hobbies include laying around, soaking up attention from her people and going for car rides with the windows down. She can be a little shy when you first meet her, but give her a minute and she warms right up -- and when she bonds, she bonds HARD! You'll have a shadow for life! She's easy to care for and does great for nail trims at home or at the groomer. Gemma was raised around kids, cats, and other foster dogs, so she's seen it all and takes it all in stride. Truly, Gemma would be great in just about any home that has room for one more big, sweet, snuggly couch cushion. Could Gemma be your new co-pilot and cuddle buddy?Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  October 21, 2026, 6:10 pm

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Mastiff shelters & rescues in Middletown, Delaware

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Middletown, Delaware. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

33.4 miles

Hinde's Animal Rescue Team

65 S Pennell Road, Media, PA 19063

Pet Types: cats, dogs, farm animals, rabbits, small animals

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Rescue

35.9 miles

Don't Bully Us Rescue

PO Box 246, Wenonah, NJ 08090

Pet Types: dogs

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Rescue

38.6 miles

Mastiffs to Mutts - Eastern PA

Exton, PA 19341

Pet Types: dogs

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Shelter

39.7 miles

Homeward Bound Pet Adoption Center - Camden County Animal Shelter

125 County House Rd, Blackwood, NJ 08012

Pet Types: cats, dogs

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Shelter

39.8 miles

Caroline County Humane Society

407 West Bell Street, Ridgely, MD 21660

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Shelter

43.7 miles

Queen Anne's County Animal Services

201 Clay Drive, Queenstown, MD 21658

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Shelter

46 miles

The Voorhees Animal Orphanage

419 Cooper Road, Voorhees, NJ 08043

Pet Types: cats, dogs

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Shelter

46.8 miles

ACCT Philly

111 W. Hunting Park Avenue, Philadelphia, PA 19140

Pet Types: cats, dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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