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Mastiff puppies and dogs in Salem, Indiana

Looking for a Mastiff puppy or dog in Salem, Indiana? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Salem, Indiana Other pups in Salem, Indiana Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Salem, Indiana Mastiff shelters and rescues in Salem, Indiana Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Salem, Indiana

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Salem, Indiana

These Mastiffs are available for adoption close to Salem, Indiana.
Photo of Eeyore

Eeyore

Mastiff

Male, 4 yrs 1 mo
Columbus, IN
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Cat Friendly: UnknownDog Friendly: UnknownKid Friendly: Yes Meet Eeyore, our lovable 4-year-old Mastiff with a heart as big as his paws. If you know Eeyore from Winnie the Pooh, you`ll understand his vibe immediately. He has that sweet, soulful expression that makes it look like he`s carrying the weight of the world on his shoulders, but underneath that gentle, slightly droopy face is a loyal companion who just wants to be near his people.

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Photo of Shay

Shay

Mastiff

Female, Senior
Loogootee, IN
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Shay is a beautiful senior Mastiff with a gentle heart and a sweet, loving personality. Despite finding herself without a home, she has remained kind, calm, and eager for affection. She enjoys spending time with people and has the quiet, loyal nature that makes Mastiffs such wonderful companions. As an older dog, Shay is past the puppy stage and appreciates the simple things in life—a soft place to rest, a leisurely stroll, and the comfort of being with someone who cares. She has so much love left to give and deserves a family who will give her the safety and happiness she's been waiting for. Shay is looking for a forever home where she can spend her golden years surrounded by love, kindness, and companionship. If you're searching for a devoted friend with a gentle soul, Shay could be the perfect addition to your family.

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Photo of Lenny

Lenny

Mastiff Mixed Breed (Medium)

Male, 1 yr 8 mos
Jasper, IN
Size
(when grown) -
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
This handsome guy is just over a year old and we believe he’s a Shepherd/Mastiff mix, weighing around 60 lbs. Lenny has been with us before as a puppy, but due to a change in his previous family’s circumstances, he has found his way back to us and is ready for a fresh start. Lenny can be a little nervous when first meeting new people, but don’t let that fool you—once he warms up, his sweet and gentle personality really shines through. With a little patience and understanding, he quickly becomes a loyal and loving companion who enjoys being close to his people. Lenny has experience living in a home environment and is AMAZING with other dogs, showing he can be a versatile companion in the right setting. Lenny would do best in a home that can give him time to adjust and build his confidence. If you’re willing to go slow and let him come out of his shell, you’ll be rewarded with a truly wonderful best friend.

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Olive

Dogo Argentino Mastiff

Female, Puppy
Brownstown, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
Meet Olive! Breed: Dogo Argentino X Mastiff Sex: Female Age: DOB ≈05/13/2026 Spayed/Neutered: Will be neutered/spayed prior to adoption Vaccinations: Age appropriate vaccines will be up to date - all vaccinations required after adoption are the responsibility of the adopter. Heartworm: Too young (testing is done at 6 months of age) Housetrained: Not yet Microchipped: Yes Adoption Fee/Donation: $400 Adoption Application Link: https://form.jotform.com/241517986810160 Important!! Think long and hard before adopting a puppy. Consider the lifestyle change this puppy will come with. He cannot be crated for more than 3-4 hours at a time until he’s older. Puppy-proofing your home will be necessary. Puppies scratch and nip, so if you have small children, can they handle this? Training will be so important in this puppy’s life. Do you have the time? Adoption donations cover pre-adoption vet costs (including vaccinations, spay/neuter, heart worm test if applicable) microchip, worming and flea/tick/heart worm (if applicable) preventatives. Donations for our young, healthy puppies and dogs support their fellow canines of advanced age or suffering from injuries and abuse whose donations are reduced but whose veterinary costs are typically much higher. We appreciate your understanding that your newly adopted dog will help others in need.

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Photo of Pepper

Pepper

Dogo Argentino Mastiff

Female, Puppy
Brownstown, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
Meet Pepper! Breed: Dogo Argentino X Mastiff Sex: Female Age: DOB ≈05/13/2026 Spayed/Neutered: Will be neutered/spayed prior to adoption Vaccinations: Age appropriate vaccines will be up to date - all vaccinations required after adoption are the responsibility of the adopter. Heartworm: Too young (testing is done at 6 months of age) Housetrained: Not yet Microchipped: Yes Adoption Fee/Donation: $400 Adoption Application Link: https://form.jotform.com/241517986810160 Important!! Think long and hard before adopting a puppy. Consider the lifestyle change this puppy will come with. He cannot be crated for more than 3-4 hours at a time until he’s older. Puppy-proofing your home will be necessary. Puppies scratch and nip, so if you have small children, can they handle this? Training will be so important in this puppy’s life. Do you have the time? Adoption donations cover pre-adoption vet costs (including vaccinations, spay/neuter, heart worm test if applicable) microchip, worming and flea/tick/heart worm (if applicable) preventatives. Donations for our young, healthy puppies and dogs support their fellow canines of advanced age or suffering from injuries and abuse whose donations are reduced but whose veterinary costs are typically much higher. We appreciate your understanding that your newly adopted dog will help others in need.

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Photo of Cheddar

Cheddar

Dogo Argentino Mastiff

Male, Puppy
Brownstown, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Salem, Indiana.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Salem, Indiana

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Mastiff shelters & rescues in Salem, Indiana

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Salem, Indiana. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

42.2 miles

Bartholomew County Humane Society

4415 E. 200 S., Columbus, IN 47201

Pet Types: cats, dogs, rabbits, small animals

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Shelter

44.9 miles

Martin County Humane Society

507 N Oak St, Loogootee, IN 47553

Pet Types: cats, dogs

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Shelter

47.5 miles

Dubois County Humane Society

426 Wernsing Rd., Jasper, IN 47546

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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