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Mastiff puppies and dogs in Indiana

Looking for a Mastiff puppy or dog in Indiana? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in Indiana Search for a Mastiff puppy or dog Mastiff puppies and dogs in Indiana cities Mastiff shelters and rescues in Indiana Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Indiana

Below are our newest added Mastiffs available for adoption in Indiana. To see more adoptable Mastiffs in Indiana, use the search tool below to enter specific criteria!
We'll also keep you updated on HERCULES's adoption status with email updates.
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HERCULES

Mastiff

Male, 3 yrs
Indianapolis, IN
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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We'll also keep you updated on Whiskey's adoption status with email updates.
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Whiskey

Mastiff

Female, 1 yr 1 mo
Angola, IN
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats,
Story
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We'll also keep you updated on Roxie's adoption status with email updates.
Special Needs
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Roxie

Mastiff/Mixed Breed (Medium)

Female, 4 yrs 5 mos
Indianapolis, IN
Size
(when grown) -
Details
Good with cats, Needs special attention,
Story
Roxie is a sweet, shy girl currently thriving in her foster home. She warms up slowly, but once she trusts you, she’s loving, goofy, and very treat-motivated. She’s done well with easygoing dogs and is still learning how to understand cats. New people and places can be overwhelming for her, so she’ll need a patient home that lets her settle at her own pace. Because she startles easily and doesn’t enjoy close handling, she’d do best in an adult-only home or one with older teens. Roxie loves car rides, does great for baths, and has some ongoing medical needs like hip dysplasia and skin/knee issues, which are managed with joint supplements and a gentle diet. If you’re looking for a loyal companion who blossoms with kindness and routine, Roxie could be the perfect match! Roxie is currently in foster—if you’d like to see if she’s a good fit, just submit an application and we’ll review it to set up a meet-and-greet with her foster. *Roxie has been waiting for her forever home for over 100 days, which makes her a Featured Pet! That means her adoption fee is completely waived—all she needs now is the right family to take her home!

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We'll also keep you updated on DIESEL's adoption status with email updates.
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DIESEL

Mastiff

Male, 7 yrs
Indianapolis, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
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We'll also keep you updated on TIGER - SOS RESCUE's adoption status with email updates.
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TIGER - SOS RESCUE

English Mastiff

Male
Morgantown, IN
Size
(when grown) -
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Story
TIGER! Mastiff mix, 14 months old, brindle Contact:  savingoutstandingsouls@gmail.com  January 29, 2026, 5:11 pm

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We'll also keep you updated on Bruce's adoption status with email updates.
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Bruce

Mastiff

Male, Adult
La Porte, IN
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Story
If you would like more information on this pet, please call the La Porte County Small Animal Shelter at 219-326-1637. Shelter hours: Monday, Thursday, Friday -- 10 am - 4 pm Tuesday, Wednesday -- 10 am - 6 pm Saturday, Sunday -- Closed Adoption Fees: Dogs/Puppies: $100.00 adoption fee includes spay/neuter, microchip, DHLP/P vaccine (Distemper, Hepatitis (CAV-2), Leptospirosis, Parainfluenza, Parvovirus), Rabies vaccine, Bordetella vaccine, CIV (Canine Influenza Vaccine), heartworm blood test, Nexgard flea treatment, fecal check, nail trim, and bath. Cat/Kitten: $75.00 adoption fee includes spay/neuter, microchip, FVRCP vaccine (Feline Viral Rhinotracheitis, Calicivirus, Panleukopenia), Rabies vaccine, FeLV/ FIV (Feline leukemia virus & feline immunodeficiency virus test), ear mite treatment, deworming, nail trim, and Revolution flea treatment.    Click for online Adoption Application:  https://us10a.sheltermanager.com/service?account=zh1519&method=online_form_html&formid=23     January 29, 2026, 4:04 pm

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Indiana.

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Mastiff puppies and dogs in Indiana cities

Mastiff Puppies near me Mastiff in Alexandria Mastiff in Anderson Mastiff in Angola Mastiff in Auburn Mastiff in Austin Mastiff in Avon Mastiff in Batesville Mastiff in Bedford Mastiff in Beech Grove Mastiff in Berne Mastiff in Bloomington Mastiff in Bluffton Mastiff in Boonville Mastiff in Brazil Mastiff in Bremen Mastiff in Brownsburg Mastiff in Carmel Mastiff in Cedar Lake Mastiff in Charlestown Mastiff in Chesterton Mastiff in Cicero Mastiff in Clarksville Mastiff in Clinton Mastiff in Columbia City Mastiff in Columbus Mastiff in Connersville Mastiff in Crawfordsville Mastiff in Crown Point Mastiff in Cumberland Mastiff in Danville Mastiff in Decatur Mastiff in Demotte Mastiff in Dyer Mastiff in East Chicago Mastiff in Edinburgh Mastiff in Elkhart Mastiff in Ellettsville Mastiff in Elwood Mastiff in Evansville Mastiff in Fishers Mastiff in Fort Wayne Mastiff in Frankfort Mastiff in Franklin Mastiff in Garrett Mastiff in Gary Mastiff in Gas City Mastiff in Goshen Mastiff in Greencastle Mastiff in Greendale Mastiff in Greenfield Mastiff in Greensburg Mastiff in Greenwood Mastiff in Griffith Mastiff in Hammond Mastiff in Hartford City Mastiff in Highland Mastiff in Hobart Mastiff in Huntingburg Mastiff in Huntington Mastiff in Indianapolis Mastiff in Jasper Mastiff in Jeffersonville Mastiff in Kendallville Mastiff in Kokomo Mastiff in Lafayette Mastiff in Lake Station Mastiff in La Porte Mastiff in Lawrence Mastiff in Lawrenceburg Mastiff in Lebanon Mastiff in Ligonier Mastiff in Linton Mastiff in Logansport Mastiff in Lowell Mastiff in Madison Mastiff in Marion Mastiff in Martinsville Mastiff in Merrillville Mastiff in Michigan City Mastiff in Mishawaka Mastiff in Mitchell Mastiff in Monticello Mastiff in Mooresville Mastiff in Mount Vernon Mastiff in Muncie Mastiff in Munster Mastiff in Nappanee Mastiff in New Albany Mastiff in New Castle Mastiff in New Haven Mastiff in New Whiteland Mastiff in Noblesville Mastiff in North Manchester Mastiff in North Vernon Mastiff in Peru Mastiff in Plainfield Mastiff in Plymouth Mastiff in Portage Mastiff in Porter Mastiff in Portland Mastiff in Princeton Mastiff in Rensselaer Mastiff in Richmond Mastiff in Rochester Mastiff in Rushville Mastiff in Saint John Mastiff in Salem Mastiff in Schererville Mastiff in Scottsburg Mastiff in Sellersburg Mastiff in Seymour Mastiff in Shelbyville Mastiff in South Bend Mastiff in Speedway Mastiff in Sullivan Mastiff in Tell City Mastiff in Terre Haute Mastiff in Tipton Mastiff in Valparaiso Mastiff in Vincennes Mastiff in Wabash Mastiff in Warsaw Mastiff in Washington Mastiff in Westfield Mastiff in West Lafayette Mastiff in Westville Mastiff in Whiteland Mastiff in Whiting Mastiff in Winchester Mastiff in Winfield Mastiff in Yorktown Mastiff in Zionsville

Mastiff shelters & rescues in Indiana

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Indiana. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

LUV A DOG Rescues and Adoptions

Morgantown , IN 46160

Pet Types: cats, dogs

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Rescue

Lucci's House Bully Rescue

Indianapolis , IN 46227

Pet Types: dogs

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Rescue

P.A.A.W.S. No-Kill Animal Rescue

Po Box 115, Newburgh , IN 47629

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Shelter

Indianapolis Animal Care Services

2600 S Harding St, Indianapolis , IN 46221

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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