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Mastiff puppies and dogs in Indiana

Looking for a Mastiff puppy or dog in Indiana? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in Indiana Search for a Mastiff puppy or dog Mastiff puppies and dogs in Indiana cities Mastiff shelters and rescues in Indiana Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Indiana

Below are our newest added Mastiffs available for adoption in Indiana. To see more adoptable Mastiffs in Indiana, use the search tool below to enter specific criteria!
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Emmy

Mastiff/Great Pyrenees

Female, 1 yr 10 mos
Boonville, IN
Size
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Titan

Mastiff

Male, 3 yrs 1 mo
Kendallville, IN
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Story
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Maddie

Mastiff/Beagle

Female, Young
La Porte, IN
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Story
If you would like more information on this pet, please call the La Porte County Small Animal Shelter at 219-326-1637. Shelter hours: Monday, Thursday, Friday -- 10 am - 4 pm Tuesday, Wednesday -- 10 am - 6 pm Saturday, Sunday -- Closed Adoption Fees: Dogs/Puppies: $100.00 adoption fee includes spay/neuter, microchip, DHLP/P vaccine (Distemper, Hepatitis (CAV-2), Leptospirosis, Parainfluenza, Parvovirus), Rabies vaccine, Bordetella vaccine, CIV (Canine Influenza Vaccine), heartworm blood test, Nexgard flea treatment, fecal check, nail trim, and bath. Cat/Kitten: $75.00 adoption fee includes spay/neuter, microchip, FVRCP vaccine (Feline Viral Rhinotracheitis, Calicivirus, Panleukopenia), Rabies vaccine, FeLV/ FIV (Feline leukemia virus & feline immunodeficiency virus test), ear mite treatment, deworming, nail trim, and Revolution flea treatment.    Click for online Adoption Application:  https://us10a.sheltermanager.com/service?account=zh1519&method=online_form_html&formid=23     May 20, 2026, 2:19 am

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Durango

Mastiff/American Pit Bull Terrier

Male, Young
Gary, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Needs experienced adopter, House-trained,
Story
I rescued Durango from an unfortunate situation where his owner became homeless. I felt so sorry for him staying in a car in the cold, below zero weather. I thought i could keep him and care for him but it turns out that there's a rule where I live that you cannot have a dog over 50 pounds. Also as i am getting up in age and cannot handle his strength and energy. I have COPD, emphysema, my health is declining pretty fast. He is very high energy and so strong. He needs obedience training that i cannot afford. He is potty trained very well. Never has accidents and let's you know he has to go out. He is 2 years old and has only had his first shots.

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Celeste

Mastiff

Female, 2 yrs 7 mos
Valparaiso, IN
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
Meet Celeste! This 2½-year-old Mastiff mix is searching for a place to call her forever home. Celeste is a true gentle giant who absolutely loves being around people. She’s incredibly affectionate and would be more than happy to be your loyal shadow throughout the day. We haven’t officially introduced her to other dogs yet, but she has shown friendly interest in them so far. Celeste is heartworm positive, but she has already started treatment—and we will continue to cover the cost even after she’s adopted. Celeste is ready to trade her kennel for a comfy couch and a family to love. Could she be the missing piece in your home?

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LOUISE

Mastiff/Shar Pei

Female, 6 yrs 1 mo
Indianapolis, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
Louise is one of those dogs who quietly works her way into your heart. She may take a moment to feel safe, but underneath that initial uncertainty is a gentle girl who truly wants to connect. Once she realizes she is with kind people, her softer side starts to shine through with little tail wags, hand kisses, and sweet moments of trust. She has already shown that she responds beautifully to patience and calm handling, and it is easy to picture her blossoming in a quieter home where she can settle in at her own pace. She seems to gain confidence from companionship and has shown a more relaxed, comfortable side once out of the stressful moments of intake. Volunteers have described her as loose, wiggly, and affectionate in the kennel once she warms up, and she has allowed handling and petting without issue. Louise is not the kind of dog who barges into the spotlight, but for someone who appreciates the quieter, tender-hearted dogs of the world, she has so much to offer. Watching a shy dog learn to trust again is one of the best feelings there is, and Louise feels like a dog who will reward patience with deep loyalty and quiet affection. All adoptions include support from our adoption team to ensure a smooth transition from the shelter to your home. Adopted pets are vaccinated, microchipped, and spayed/neutered before leaving the shelter`s care. To view our current available animals, please visit: [https://indy.gov/activity/adopt-a-pet](https://indy.gov/activity/adopt-a-pet).

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Indiana.

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Mastiff puppies and dogs in Indiana cities

Mastiff Puppies near me Mastiff in Alexandria Mastiff in Anderson Mastiff in Angola Mastiff in Auburn Mastiff in Austin Mastiff in Avon Mastiff in Batesville Mastiff in Bedford Mastiff in Beech Grove Mastiff in Berne Mastiff in Bloomington Mastiff in Bluffton Mastiff in Boonville Mastiff in Brazil Mastiff in Bremen Mastiff in Brownsburg Mastiff in Carmel Mastiff in Cedar Lake Mastiff in Charlestown Mastiff in Chesterton Mastiff in Cicero Mastiff in Clarksville Mastiff in Clinton Mastiff in Columbia City Mastiff in Columbus Mastiff in Connersville Mastiff in Crawfordsville Mastiff in Crown Point Mastiff in Cumberland Mastiff in Danville Mastiff in Decatur Mastiff in Demotte Mastiff in Dyer Mastiff in East Chicago Mastiff in Edinburgh Mastiff in Elkhart Mastiff in Ellettsville Mastiff in Elwood Mastiff in Evansville Mastiff in Fishers Mastiff in Fort Wayne Mastiff in Frankfort Mastiff in Franklin Mastiff in Garrett Mastiff in Gary Mastiff in Gas City Mastiff in Goshen Mastiff in Greencastle Mastiff in Greendale Mastiff in Greenfield Mastiff in Greensburg Mastiff in Greenwood Mastiff in Griffith Mastiff in Hammond Mastiff in Hartford City Mastiff in Highland Mastiff in Hobart Mastiff in Huntingburg Mastiff in Huntington Mastiff in Indianapolis Mastiff in Jasper Mastiff in Jeffersonville Mastiff in Kendallville Mastiff in Kokomo Mastiff in Lafayette Mastiff in Lake Station Mastiff in La Porte Mastiff in Lawrence Mastiff in Lawrenceburg Mastiff in Lebanon Mastiff in Ligonier Mastiff in Linton Mastiff in Logansport Mastiff in Lowell Mastiff in Madison Mastiff in Marion Mastiff in Martinsville Mastiff in Merrillville Mastiff in Michigan City Mastiff in Mishawaka Mastiff in Mitchell Mastiff in Monticello Mastiff in Mooresville Mastiff in Mount Vernon Mastiff in Muncie Mastiff in Munster Mastiff in Nappanee Mastiff in New Albany Mastiff in New Castle Mastiff in New Haven Mastiff in New Whiteland Mastiff in Noblesville Mastiff in North Manchester Mastiff in North Vernon Mastiff in Peru Mastiff in Plainfield Mastiff in Plymouth Mastiff in Portage Mastiff in Porter Mastiff in Portland Mastiff in Princeton Mastiff in Rensselaer Mastiff in Richmond Mastiff in Rochester Mastiff in Rushville Mastiff in Saint John Mastiff in Salem Mastiff in Schererville Mastiff in Scottsburg Mastiff in Sellersburg Mastiff in Seymour Mastiff in Shelbyville Mastiff in South Bend Mastiff in Speedway Mastiff in Sullivan Mastiff in Tell City Mastiff in Terre Haute Mastiff in Tipton Mastiff in Valparaiso Mastiff in Vincennes Mastiff in Wabash Mastiff in Warsaw Mastiff in Washington Mastiff in Westfield Mastiff in West Lafayette Mastiff in Westville Mastiff in Whiteland Mastiff in Whiting Mastiff in Winchester Mastiff in Winfield Mastiff in Yorktown Mastiff in Zionsville

Mastiff shelters & rescues in Indiana

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Indiana. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Homeward Bound Animal Welfare Group

Mishawaka , IN 46546

Pet Types: dogs

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Shelter

La Porte County Small Animal Shelter

2855 West State Road 2, La Porte , IN 46350

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

Giant Paw Prints, Inc.

857 W Main St, Westville , IN 46391

Pet Types: dogs

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Shelter

Porter County Animal Shelter

3355 S Bertholet Boulevard, Valparaiso , IN 46383

Pet Types: cats, dogs

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Shelter

Lakeshore PAWS

4611 Evans Ave, Valparaiso , IN 46383

Pet Types: dogs

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Shelter

Humane Society of Noble County, Inc.

1305 Sherman Street, Kendallville , IN 46755

Pet Types: cats, dogs, rabbits, small animals

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Rescue

Big Dogs Don't Cry

Merrilliville , IN 46410

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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