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Mastiff puppies and dogs in Indiana

Looking for a Mastiff puppy or dog in Indiana? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in Indiana Search for a Mastiff puppy or dog Mastiff puppies and dogs in Indiana cities Mastiff shelters and rescues in Indiana Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Indiana

Below are our newest added Mastiffs available for adoption in Indiana. To see more adoptable Mastiffs in Indiana, use the search tool below to enter specific criteria!
We'll also keep you updated on Nyla's adoption status with email updates.
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Nyla

Mastiff/German Shepherd Dog

Female, Young
Gary, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
Meet Nyla! She is a sweet, shy, gentle girl who survived a very rough start. Nyla came from a severely neglected litter and was rescued malnourished, scared, and very weak. Today she is calm, intelligent, and loving once she feels safe. She softly licks your hand, enjoys head scratches, and gets along well with other dogs. She loves to sniff and explore and would thrive with a family who enjoys walks or outdoor time. Because of early food scarcity, she may show light resource guarding (only gentle growls). She can also jump a 4-ft fence, so she must be on leash outdoors unless in a secure dog park or designated off-leash area. Nyla is not high energy but needs more attention, structure, and exercise than my parents can provide. She is still growing and has so much potential. Requirements: reference check, vet verification, and home check. Nyla deserves a patient, loving forever home.

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We'll also keep you updated on SUNSHINE's adoption status with email updates.
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SUNSHINE

Mastiff

Female, 2 yrs
Indianapolis, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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We'll also keep you updated on Tess's adoption status with email updates.
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Tess

Mastiff

Female, 2 yrs 7 mos
AUBURN, IN
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
-
Story
An adoption application can be filled out on the DHS website https://www.dekalbhumanesociety.org/adopt. Dog adoption fees are $200.00 for all puppies and adult dogs. Seniors are a donation of choice.Cats and kittens are a donation of choice.

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We'll also keep you updated on MAX's adoption status with email updates.
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MAX

Mastiff

Male, 2 yrs 2 mos
Indianapolis, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with dogs,
Story
-

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We'll also keep you updated on Skye's adoption status with email updates.
Photo of Skye

Skye

Mastiff/Mixed Breed (Medium)

Female, 1 yr 3 mos
Wabash, IN
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs,
Story
🐾 Meet Skye! 🐾Skye is a Mastiff/German Shephard mix who’s ready to fly into her forever home! 🩷✈️She’s spayed, up to date on vaccines, and always ready for adventure.This social girl loves everyone she meets and does great with her brother, Chase. She hasn’t been tested with other dogs or cats yet, but we have no doubt she’ll make fast friends. Skye’s love language is affection — she’s full of kisses, curiosity, and charm, and she’s ready to soar into your heart! 💕🐶“This pup’s gotta fly!” 🐾✨

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We'll also keep you updated on TIGER - SOS RESCUE's adoption status with email updates.
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TIGER - SOS RESCUE

English Mastiff

Male
Morgantown, IN
Size
(when grown) -
Details
-
Story
TIGER! Mastiff mix, 14 months old, brindle Contact:  savingoutstandingsouls@gmail.com  October 14, 2025, 10:06 pm

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Indiana.

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Mastiff puppies and dogs in Indiana cities

Mastiff Puppies near me Mastiff in Alexandria Mastiff in Anderson Mastiff in Angola Mastiff in Auburn Mastiff in Austin Mastiff in Avon Mastiff in Batesville Mastiff in Bedford Mastiff in Beech Grove Mastiff in Berne Mastiff in Bloomington Mastiff in Bluffton Mastiff in Boonville Mastiff in Brazil Mastiff in Bremen Mastiff in Brownsburg Mastiff in Carmel Mastiff in Cedar Lake Mastiff in Charlestown Mastiff in Chesterton Mastiff in Cicero Mastiff in Clarksville Mastiff in Clinton Mastiff in Columbia City Mastiff in Columbus Mastiff in Connersville Mastiff in Crawfordsville Mastiff in Crown Point Mastiff in Cumberland Mastiff in Danville Mastiff in Decatur Mastiff in Demotte Mastiff in Dyer Mastiff in East Chicago Mastiff in Edinburgh Mastiff in Elkhart Mastiff in Ellettsville Mastiff in Elwood Mastiff in Evansville Mastiff in Fishers Mastiff in Fort Wayne Mastiff in Frankfort Mastiff in Franklin Mastiff in Garrett Mastiff in Gary Mastiff in Gas City Mastiff in Goshen Mastiff in Greencastle Mastiff in Greendale Mastiff in Greenfield Mastiff in Greensburg Mastiff in Greenwood Mastiff in Griffith Mastiff in Hammond Mastiff in Hartford City Mastiff in Highland Mastiff in Hobart Mastiff in Huntingburg Mastiff in Huntington Mastiff in Indianapolis Mastiff in Jasper Mastiff in Jeffersonville Mastiff in Kendallville Mastiff in Kokomo Mastiff in Lafayette Mastiff in Lake Station Mastiff in La Porte Mastiff in Lawrence Mastiff in Lawrenceburg Mastiff in Lebanon Mastiff in Ligonier Mastiff in Linton Mastiff in Logansport Mastiff in Lowell Mastiff in Madison Mastiff in Marion Mastiff in Martinsville Mastiff in Merrillville Mastiff in Michigan City Mastiff in Mishawaka Mastiff in Mitchell Mastiff in Monticello Mastiff in Mooresville Mastiff in Mount Vernon Mastiff in Muncie Mastiff in Munster Mastiff in Nappanee Mastiff in New Albany Mastiff in New Castle Mastiff in New Haven Mastiff in New Whiteland Mastiff in Noblesville Mastiff in North Manchester Mastiff in North Vernon Mastiff in Peru Mastiff in Plainfield Mastiff in Plymouth Mastiff in Portage Mastiff in Porter Mastiff in Portland Mastiff in Princeton Mastiff in Rensselaer Mastiff in Richmond Mastiff in Rochester Mastiff in Rushville Mastiff in Saint John Mastiff in Salem Mastiff in Schererville Mastiff in Scottsburg Mastiff in Sellersburg Mastiff in Seymour Mastiff in Shelbyville Mastiff in South Bend Mastiff in Speedway Mastiff in Sullivan Mastiff in Tell City Mastiff in Terre Haute Mastiff in Tipton Mastiff in Valparaiso Mastiff in Vincennes Mastiff in Wabash Mastiff in Warsaw Mastiff in Washington Mastiff in Westfield Mastiff in West Lafayette Mastiff in Westville Mastiff in Whiteland Mastiff in Whiting Mastiff in Winchester Mastiff in Winfield Mastiff in Yorktown Mastiff in Zionsville

Mastiff shelters & rescues in Indiana

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Indiana. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Kokomo Humane Society

729 E. Hoffer St, Kokomo , IN 46902

Pet Types: cats, birds, dogs, rabbits, small animals

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Shelter

Wabash County Animal Shelter

810 Manchester Ave, Wabash , IN 46992

Pet Types: cats, dogs

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Shelter

Porter County Animal Shelter

3355 S Bertholet Boulevard, Valparaiso , IN 46383

Pet Types: cats, dogs

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Rescue

Giant Paw Prints, Inc.

857 W Main St, Westville , IN 46391

Pet Types: dogs

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Shelter

IndyHumane

7929 N. Michigan Rd, Indianapolis , IN 46268

Pet Types: cats, dogs

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Rescue

Homeward Bound Animal Welfare Group

Mishawaka , IN 46546

Pet Types: dogs

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Rescue

Sketchy Mutts and Underdogs

Indianapolis , IN 46222

Pet Types: dogs

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Rescue

S.O.A.R. Initiative, Inc.

4025 W 10th St, Indianapolis , IN 46222

Pet Types: cats, dogs

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Rescue

Animal House Sanctuary

185 W 416 S, Indianapolis , IN 46204

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Shelter

Indianapolis Animal Care Services

2600 S Harding St, Indianapolis , IN 46221

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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