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Mastiff puppies and dogs in Lawrence, Massachusetts

Looking for a Mastiff puppy or dog in Lawrence, Massachusetts? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Lawrence, Massachusetts

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These Mastiffs are available for adoption close to Lawrence, Massachusetts.
Photo of Mark

Mark

Mastiff Mixed Breed (Medium)

Male, 2 yrs 4 mos
Salem, NH
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Hello there, I'm Mark! I may be young, but I've got a heart full of love to give. Every morning, I wake up excited for the day ahead. I love playing with my favorite chew toy, but what I really crave is a good game of fetch with a human friend. I'm a quick learner, too! I've already mastered 'sit' and 'stay', and I'm eager to learn more. I promise to be your loyal companion, always ready for an adventure or a cozy nap on the couch. I'm not just looking for a home, I'm looking for a family. Adopt me and let's create a lifetime of wonderful memories together.
Photo of Alamo

Alamo

Mastiff Mixed Breed (Medium)

Male, 5 yrs
Salem, NH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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Photo of Gracie

Gracie

Mastiff Labrador Retriever

Male, 9 mos
Salem, NH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Gracie, a bundle of joyful energy and loyalty! This little girl will bring laughter and love into your home with her playful and affectionate nature. Gracie is an intelligent pup who is always up for an adventure, and with her athletic build, she'll be your active companion. She has a heart of gold and a funny, loving spirit that will keep you on your toes. Gracie is eager to find her forever family and will be a devoted friend to whoever adopts her. Could that be you?
Photo of Neo

Neo

Mastiff

Male, Adult
Revere, MA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
Neo is about 4 years old and is a Mastiff mix. I’ve had him since he was 2 months old after a friend’s dogs had an unexpected litter, and he has been raised in a loving home his entire life. Neo is a big, sweet boy who loves being close to his person. He can be skittish around new people and situations and needs a little time to warm up, but once he feels comfortable, he is incredibly affectionate and loyal. He loves relaxing around the house, being near his people, and sleeping in bed with me every night. Neo is completely house trained and has completed several weeks of professional training. He is extremely strong and still pulls on the leash, so he needs someone capable of handling a large dog. His ideal home would be with someone patient who will give him time to adjust and build trust. Neo is up to date on vaccinations, receives Simparica Trio monthly, has yearly veterinary checkups, has no special medical needs, and is not neutered. He is the sweetest boy you'll ever meet.
Photo of Tootsie Roll

Tootsie Roll

Mastiff English Mastiff

Female, Adult
Westminster, MA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Tootsie Roll! This 5-year old English Mastiff Mix is a loyal and devoted gentle giant who came to us after her owner could no longer care for her and is ready to bond hard with her people. Her fun-loving personality is chewy-yet-soft…Tootsie-Pootsie is just a super sweet gal who loves affection and attention and isn’t afraid to show it! With the most loving demeanor around, she will stare into your soul with her incredibly human-like eyes and instantly melt your heart. She is known to sit in front of you and lean allllll her weight into your legs as her version of a hug and sometimes forgets she isn’t lap sized. She will lovingly follow you everywhere, even the bathroom, and will proudly show her love every chance she gets!  At a whopping 100 lbs, Tootsie is just a tad bigger than a candy treat. Majestic and big-boned? Yes! But a mellow gal at heart who has mastered couch napping as if it’s an Olympic sport. And though she appreciates being outside and romping around, committing to short spurts or leisurely strolls is more her speed. Sure…Toots lives in a bigger body but is scared of an ironing board on its side and can easily be contained in a room by putting one down to block off a door opening, even though she could walk right over it. She absolutely loves car rides, belly rubs, toys, gobbling up treats, and sniffing to her hearts content inside and outside! She loves fruit and will enthusiastically eat raspberries right off the bush. She is uber housetrained and has been trained to poop in the woods like a lady. Oh, and you must enthusiastically love slobber, because with those jowls, it’s naturally expected.  Tootsy-Wootsy has a classically beautiful chocolate-colored brindle coat, and one adorable and iconic snaggletooth constantly protruding from her adorable underbite. She currently lives with a 25 lb mini doodle and is really appropriate with playtime and snuggle time despite their obvious size discrepancy (cats unknown). Due to sheer size and lack of history, older or no kids would be best for this smooth and sweet Tootie Pop. Tootsie Roll’s top 3 priorities: 1. A family who is excited to LOVE! Tootsie craves physical touch, affection, and engagement with her humans.  2. A family who wants to be LOVED! This darling girl isn’t afraid to show her adoration, and sloppy kisses are definitely part of the deal. 3. A family with large breed experience. Tootsie is Chihuahua-sized at heart, but owning an XL dog means extra cost for just about everything such as food, equipment, and preventatives, and can amplify the consequences of every single action (i.e. jumping or clearing a room with one “toot”, which quite honestly only happens on occasion).August 11, 2026, 12:03 am
Photo of Hector *FOSTER NEEDED TOO!

Hector *FOSTER NEEDED TOO!

Staffordshire Bull Terrier Mastiff

Male, Senior
Kittery, ME
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with cats, House-trained, Spayed or Neutered,
Story
Please contact Tammy for more information about this pet.Easy-going family manA Letter from Hector To My Future Family… Hi, it’s me—Hector. You may not know me yet, but I’ve been waiting for you. I’m 10 years old, around 70 lbs, and I’ve spent the last 3 years hoping someone like you would come along. I’ve had homes before… some good, some not so much. I’ve been returned, lost, and forgotten. Once, I even walked myself back to the shelter gates because, deep down, I knew I deserved better. And I still believe I do. I’m not asking for much—just a soft place to land and someone who means it when they say “forever.” I’m house-trained, crate-trained, and I know my commands. I also just got a great health report from the vet. Aside from a little arthritis, I'm healthy as a horse. Yeehaw! I love snuggles, slow strolls, and feeling like I belong. I’m gentle with people and can live with sturdy kids. I get along with some dog friends too—just no cats, please. My caretaker says I’m loyal, low-key, and full of love. I just need a home where I can finally exhale and know I’m safe. Where I can lay my head down and not worry about being left again. So if you're out there—my person, my family—please come find me. I've waited a long time, but I still believe you're coming. Love, Hector See my latest videos: bit.ly/findhector Questions? adopt@doggieharmony.org Apply to adopt: www.doggieharmony.org (click Forms) Even if you can’t adopt Hector, please share his story. His forever is out there—we just have to help it find him.August 14, 2026, 1:12 pm

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Mastiff shelters & rescues in Lawrence, Massachusetts

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Lawrence, Massachusetts. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

7.4 miles

Lucky's Legacy Rescue - NH Transport Stop

Salem, NH 03079

Pet Types: cats, dogs, small animals

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Rescue

7.4 miles

Lucky Tails Rescue - NH transport

Salem, NH 03079

Pet Types: dogs

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Rescue

38.9 miles

Crops and Flops Rescue

Westminster, MA 01473

Pet Types: dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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