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Mastiff puppies and dogs in Massachusetts

Looking for a Mastiff puppy or dog in Massachusetts? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in Massachusetts Search for a Mastiff puppy or dog Mastiff puppies and dogs in Massachusetts cities Mastiff shelters and rescues in Massachusetts Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Massachusetts

Below are our newest added Mastiffs available for adoption in Massachusetts. To see more adoptable Mastiffs in Massachusetts, use the search tool below to enter specific criteria!
We'll also keep you updated on Ardis's adoption status with email updates.
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Ardis

Mastiff

Female, Puppy
Boston, MA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats,
Story
**MEET ME AT OUR 12/13 ADOPTION EVENT IN DORCHESTER!**Adoptable in: MA, RI, NH, CT, and VTGood with dogs: YesGood with cats: YesGood with kids: Yes, dog savvy childrenCrate trained: YesHouse Trained: Mostly Ardis is a happy, sweet and good girl. She has the cutest little wrinkles next to her mouth when she smiles and her tongue is usually lolling. She has a medium energy level and would love a family who will share their adventures with her.Ardis is very excited when she meets other dogs and can’t wait to play with them. She would do best with other dogs who are as enthusiastic as she is about playtime! She has met a cat and backed away when it hissed at her, so would most likely coexist just fine with a cat sibling. Ardis has been around young kids and did well, but she is still perfecting her manners, so dog savvy kids would be best. She likes to play tug-of-war and wrestle with other dogs.Ardis will go in her crate happily and settles straight away. She is mostly house trained so long as her cues are not missed. She is learning basic commands and how to walk on a leash.Ardis is a playful girl with lots of love to give her new family! Is yours the one she’s been waiting for? Please Note: All dogs are posted on our website until they are officially adopted. This dog may have other interested adopters in line. If you are interested in adopting, please fill out an application on our website at www.lasthopek9.org. Last Hope K9 Rescue is licensed with the Massachusetts Department of Agricultural Resources (#0151).December 8, 2025, 12:20 am

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We'll also keep you updated on ALEX's adoption status with email updates.
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ALEX

Mastiff/Chow Chow

Male, 2 yrs 7 mos
Boston, MA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
MY ADOPTION FEE WILL BE WAIVED 12/08-12/14!Meet Alex a lively, lovable pup with a big personality and an even bigger heart. Alex is currently on the road to recovery after TPLO surgery and is recovering from heartworm treatment. While he is on activity restriction for now, do not let that fool you, this boy has energy to spare and a playful spirit thats just waiting to shine once he has healed.Because of his high energy and temporary limitations, Alex will need a patient and experienced home that can help him channel that zest for life into brain games, enrichment activities, and plenty of mental stimulation. He is working hard on being a good boy during recovery, and he is making great progress with structure and support.When he has had his fill of mental fun and the zoomies are out of his system, Alex melts into a total cuddle bug. If you`re looking for a smart, spirited companion and you`re ready to help guide him through his healing journey, this squishy guy just might be your perfect match.

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We'll also keep you updated on Yeager's adoption status with email updates.
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Yeager

Mastiff/American Pit Bull Terrier

Male, 7 yrs
Amherst, MA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Needs experienced adopter, House-trained,
Story
Meet Yeager! A devoted six-and-a-half-year-old Mastiff, American Pitbull Terrier, and Great Pyrenees mix currently living in Bethlehem, CT, whose heart is as big as his 70-pound frame. With a brindled fawn-colored coat that gleams in the sunlight and a soul that craves connection, Yeager is a lovable blend of strength, sweetness, and sensitivity. Yeager is the ultimate running partner and sunbathing enthusiast. Whether he's bounding beside you on a trail or sprawled out in a sunbeam with his paws in the air, he’s happiest just being near his people! Around kids, he shines—gentle and obedient, especially during mealtime when he’ll sit patiently with drool dripping in anticipation until he hears the magic word: “free!” He’s also crate-trained and house-trained, and though he does require a sturdy, escape-proof crate, he often chooses to snuggle up in it all on his own—it’s his safe little haven. Yeager’s heart is warm and full of affection, but it’s also a bit tender. After a traumatic veterinary experience a couple of years ago, he’s become more cautious around unfamiliar people. While he has never bitten anyone, he may growl or snap at the air when he feels unsafe. He’s working on his trust-building journey with the help of medication and positive reinforcement, but his next family should be patient and understanding—someone who will give him the calm, loving space he needs to settle in and thrive. He gets along famously with other dogs, having a blast with his canine cousins, and he’s an affectionate cuddle-bug to his human family! However, a home without cats or one experienced with slow introductions would be best due to his excitable play style. He’s also terrified of thunderstorms and fireworks, so a peaceful setting and a patient caregiver during loud events will help him feel secure. Yeager’s story is one of resilience, loyalty, and deep love. Are you the kind soul who can offer this beautiful boy the safety, companionship, and calm environment he needs to flourish in his next chapter? To learn more or welcome Yeager into your life, please reach out to adopt@joyfulpets.com!

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Massachusetts.

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Mastiff puppies and dogs in Massachusetts cities

Mastiff Puppies near me Mastiff in Agawam Mastiff in Attleboro Mastiff in Barnstable Mastiff in Beverly Mastiff in Boston Mastiff in Brockton Mastiff in Cambridge Mastiff in Chelsea Mastiff in Chicopee Mastiff in Easthampton Mastiff in Everett Mastiff in Fall River Mastiff in Fitchburg Mastiff in Franklin Mastiff in Gardner Mastiff in Gloucester Mastiff in Haverhill Mastiff in Holyoke Mastiff in Lawrence Mastiff in Leominster Mastiff in Lowell Mastiff in Lynn Mastiff in Malden Mastiff in Marlborough Mastiff in Medford Mastiff in Melrose Mastiff in Methuen Mastiff in New Bedford Mastiff in Newburyport Mastiff in Newton Mastiff in North Adams Mastiff in Northampton Mastiff in Peabody Mastiff in Pittsfield Mastiff in Quincy Mastiff in Revere Mastiff in Salem Mastiff in Somerville Mastiff in Springfield Mastiff in Taunton Mastiff in Waltham Mastiff in Watertown Mastiff in Westfield Mastiff in West Springfield Mastiff in Woburn Mastiff in Worcester

Mastiff shelters & rescues in Massachusetts

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Massachusetts. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Joyful Pets Rescue

Private Foster Homes, Amherst , MA 01002

Pet Types: cats, dogs, rabbits, small animals

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Shelter

MSPCA - Boston Adoption Center

350 South Huntington Avenue, Boston , MA 02130

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

Last Hope K9 Rescue

71 Commercial St, #184, Boston , MA 02113

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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