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Mastiff puppies and dogs in Salem, Massachusetts

Looking for a Mastiff puppy or dog in Salem, Massachusetts? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Salem, Massachusetts Other pups in Salem, Massachusetts Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Salem, Massachusetts Mastiff shelters and rescues in Salem, Massachusetts Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Salem, Massachusetts

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Salem, Massachusetts

These Mastiffs are available for adoption close to Salem, Massachusetts.
Photo of Neo

Neo

Mastiff

Male, Adult
Revere, MA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
Neo is about 4 years old and is a Mastiff mix. I’ve had him since he was 2 months old after a friend’s dogs had an unexpected litter, and he has been raised in a loving home his entire life. Neo is a big, sweet boy who loves being close to his person. He can be skittish around new people and situations and needs a little time to warm up, but once he feels comfortable, he is incredibly affectionate and loyal. He loves relaxing around the house, being near his people, and sleeping in bed with me every night. Neo is completely house trained and has completed several weeks of professional training. He is extremely strong and still pulls on the leash, so he needs someone capable of handling a large dog. His ideal home would be with someone patient who will give him time to adjust and build trust. Neo is up to date on vaccinations, receives Simparica Trio monthly, has yearly veterinary checkups, has no special medical needs, and is not neutered. He is the sweetest boy you'll ever meet.

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Photo of Mark

Mark

Mastiff Mixed Breed (Medium)

Male, 2 yrs 4 mos
Salem, NH
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Hello there, I'm Mark! I may be young, but I've got a heart full of love to give. Every morning, I wake up excited for the day ahead. I love playing with my favorite chew toy, but what I really crave is a good game of fetch with a human friend. I'm a quick learner, too! I've already mastered 'sit' and 'stay', and I'm eager to learn more. I promise to be your loyal companion, always ready for an adventure or a cozy nap on the couch. I'm not just looking for a home, I'm looking for a family. Adopt me and let's create a lifetime of wonderful memories together.

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Photo of Alamo

Alamo

Mastiff Mixed Breed (Medium)

Male, 5 yrs
Salem, NH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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Photo of Gracie

Gracie

Mastiff Labrador Retriever

Male, 9 mos
Salem, NH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Gracie, a bundle of joyful energy and loyalty! This little girl will bring laughter and love into your home with her playful and affectionate nature. Gracie is an intelligent pup who is always up for an adventure, and with her athletic build, she'll be your active companion. She has a heart of gold and a funny, loving spirit that will keep you on your toes. Gracie is eager to find her forever family and will be a devoted friend to whoever adopts her. Could that be you?

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Photo of Hector *FOSTER NEEDED TOO!

Hector *FOSTER NEEDED TOO!

Staffordshire Bull Terrier Mastiff

Male, Senior
Kittery, ME
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with cats, House-trained, Spayed or Neutered,
Story
Please contact Tammy for more information about this pet.Easy-going family manA Letter from Hector To My Future Family… Hi, it’s me—Hector. You may not know me yet, but I’ve been waiting for you. I’m 10 years old, around 70 lbs, and I’ve spent the last 3 years hoping someone like you would come along. I’ve had homes before… some good, some not so much. I’ve been returned, lost, and forgotten. Once, I even walked myself back to the shelter gates because, deep down, I knew I deserved better. And I still believe I do. I’m not asking for much—just a soft place to land and someone who means it when they say “forever.” I’m house-trained, crate-trained, and I know my commands. I also just got a great health report from the vet. Aside from a little arthritis, I'm healthy as a horse. Yeehaw! I love snuggles, slow strolls, and feeling like I belong. I’m gentle with people and can live with sturdy kids. I get along with some dog friends too—just no cats, please. My caretaker says I’m loyal, low-key, and full of love. I just need a home where I can finally exhale and know I’m safe. Where I can lay my head down and not worry about being left again. So if you're out there—my person, my family—please come find me. I've waited a long time, but I still believe you're coming. Love, Hector See my latest videos: bit.ly/findhector Questions? adopt@doggieharmony.org Apply to adopt: www.doggieharmony.org (click Forms) Even if you can’t adopt Hector, please share his story. His forever is out there—we just have to help it find him.August 14, 2026, 1:12 pm

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Mastiff puppies and dogs in nearby cities

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Related breeds in Salem, Massachusetts

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Mastiff shelters & rescues in Salem, Massachusetts

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Salem, Massachusetts. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

25.2 miles

Lucky's Legacy Rescue - NH Transport Stop

Salem, NH 03079

Pet Types: cats, dogs, small animals

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Rescue

25.2 miles

Lucky Tails Rescue - NH transport

Salem, NH 03079

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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