Adopt
Rehome
Menu Hamburger Icon

Mastiff puppies and dogs in Adrian, Michigan

Looking for a Mastiff puppy or dog in Adrian, Michigan? Adopt a Pet can help you find an adorable Mastiff near you.

Picture of Mastiff

Learn More:

Adopt a Mastiff near you Mastiff in cities near Adrian, Michigan Other pups in Adrian, Michigan Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Adrian, Michigan Mastiff shelters and rescues in Adrian, Michigan Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Adrian, Michigan

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Adrian, Michigan

These Mastiffs are available for adoption close to Adrian, Michigan.
We'll also keep you updated on Rocco's adoption status with email updates.
Photo of Rocco

Rocco

Mastiff

Male, 4 yrs 5 mos
Ann Arbor, MI
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Hiya! My name is Rocco! I am a fun loving and super sweet dog looking for my forever home! I love almost everyone I meet, including other animals! Despite my love for everyone, I can sometimes be a bit too excited making me not a perfect fit for some households. I will need a home without kids under 12, and possibly without cats due to my overexcitement. I will need an adopter who is comfortable with big dogs like me, and comfortable helping me learn some manners. I will be a great dog for anyone looking for a big teddy bear with a heart of gold! I love to play and run around, but mostly I love being around people who love me, and I would love to add you to that list!

Learn More

Small right facing arrow
We'll also keep you updated on Maisy's adoption status with email updates.
Photo of Maisy

Maisy

Mastiff

Female, 5 yrs 6 mos
Belleville, MI
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Meet Maisy! Maisy is a 5-year-old Mastiff mix with a heart as big as her paws! She came to us as a stray from Sumpter, severely underweight and clearly having been through a lot. But oh, how far she's come! With time, love, and plenty of good meals, Maisy has transformed into a healthy, happy pup who's ready for her forever home. Despite her tough start, Maisy's outlook on life is nothing short of amazing. She's always wiggly with excitement to see people and has never met a stranger-she's as friendly and affectionate as they come. Her favorite things? Stuffy toys (even if they only last a few minutes), snacks (she's very food motivated), and simply hanging out with her humans. Maisy is still learning the ropes of home life, including potty training and basic manners, but her eagerness to please and strong bond with her people make her a great student. She's mellow by nature and prefers relaxed exploration in the yard over high-energy activities. While she hasn't quite figured out how to "play" just yet, we can tell she's curious and interested-and with time, she might just become a pro! She's currently unsure around other dogs but has done fine in calm playgroups, mostly keeping to herself. If you already have a dog at home, we're still happy to consider a meet-and-greet to see how they might get along. As for cats-we're not sure yet. Maisy would do best in a moderately active home, possibly with older kids and maybe a laid-back dog sibling. Most importantly, she needs a patient and loving family who can help her continue her journey from survivor to spoiled companion. If you're looking for a sweet, soulful, easygoing girl to share your heart and home with-Maisy might just be your perfect match. ---------------------------------------------------------------------------------------------------------------------------------- If you would like to meet Maisy, please submit an application for her on our website https://www.friendsofmichigan.org/adoptable-dogs. She is spayed, up to date on all age appropriate vaccines, microchipped, and on monthly flea & tick prevention. Maisy is currently heartworm positive, and has begun her treatment as of 5/8/25. FMAR covers the full cost of heartworm treatment and works with Home Care Veterinary Services for the treatment. You're still encouraged to apply to adopt Maisy! We'll work closely with you to ensure her treatment continues smoothly and she gets everything she needs to thrive in her new home. Her treatment after adoption would continue through HCVS until successfully completed. Her adoption fee is $250, which helps cover the cost of the medical care she has received. **Please note that the breed listed for each of our dogs is a rough estimate unless DNA results are provided in their Bio. All strays have rough estimates of their age based on the condition of their teeth. Each dog is different, so each adoption is different. Our adoption process might require multiple visits to the shelter before our dogs can go home. Or they may be ready on the first visit. It really depends on the individual dog and the potential adopters. Once we receive your application, the Dog Staff will contact you to discuss meeting our dogs.

Learn More

Small right facing arrow
We'll also keep you updated on Serena's adoption status with email updates.
Photo of Serena

Serena

Mastiff German Shepherd Dog

Female, Puppy
Toledo, OH
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
My name is Serena, I am a Mastiff Shepherd mix born 7/13/25. My foster mom says I’m named after the goat, whatever that means. I’m going to be a big girl! I have a very curious nature, I love to play with the other dogs in my home but can also entertain myself with toys and if you’re handing out belly rubs I’m your girl! I’m looking for a family who will grow with me and help me be your ultimate best friend. I am doing well on my crate and potty training. Puppy class is recommended. Applicants should reside within a half hour of Toledo and have a history of current vaccines and heartworm preventative for any current or former pets. Due to high volume, inquiries made on petfinder and adoptapet will not be answered. Please complete an application on our website https://toledospetbullproject.com/adoption/

Learn More

Small right facing arrow
We'll also keep you updated on Daisy's adoption status with email updates.
Photo of Daisy

Daisy

Mastiff

Female, Young
Belleville, MI
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs,
Story
You can fill out an adoption application online on our official website.Meet Daisy 7–8 Month Old Mastiff Mix | Playful, Sweet, and Ready to Bloom Looking for a goofy, loving sidekick who’s equal parts cuddlebug and adventure buddy? Meet Daisy—a young Mastiff mix (maybe with a little Cane Corso and Southern hunting dog in her roots) who’s as fun as she is unique. Daisy came to us after her previous owner made the heartbreaking decision to surrender her in order to care for a family member battling stage 4 cancer. While she may have lost her first home, Daisy hasn’t lost her joy—this girl is all wagging tails, play bows, and puppy kisses. She’s a petite powerhouse for a Mastiff mix, but don’t let her size fool you—Daisy is full of energy, love, and personality. She’s already shown how great she is with kids and had a blast playing with a large male dog. Her perfect match? A home with another playful pup or an active human who’s ready to run, romp, and laugh along with her. Still in her puppy phase, Daisy is eager to learn, bond, and bring light to the lucky family who gives her a forever home. Good with kids Dog-friendly (especially with playful, large companions!) Young, active, and tons of fun This sweet girl is ready to put down roots. Could you be the sunshine in Daisy’s next chapter?Visit this organization's web site to see any additional information available about this pet.July 14, 2025, 8:48 pm

Learn More

Small right facing arrow
We'll also keep you updated on Dandelion's adoption status with email updates.
Photo of Dandelion

Dandelion

Mastiff

Female, 7 yrs 1 mo
Monroe, MI
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

Learn More

Small right facing arrow
We'll also keep you updated on Benny's adoption status with email updates.
Photo of Benny

Benny

Mastiff

Male, 6 yrs 1 mo
Monroe, MI
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

Learn More

Small right facing arrow

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Adrian, Michigan.

    an arrow icon
location arrow icon Current location
  • New York, NY
  • Los Angeles, CA
  • Houston, TX
  • Dallas, TX
  • El Paso, TX

Sorry, we can’t find that location! Please try again.

    Age
    an arrow icon

Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Ann Arbor, MI Mastiff in Chelsea, MI Mastiff in Hillsdale, MI Mastiff in Jackson, MI Mastiff in Maumee, OH Mastiff in Milan, MI Mastiff in Monroe, MI Mastiff in Northwood, OH Mastiff in Oregon, OH Mastiff in Perrysburg, OH Mastiff in Rossford, OH Mastiff in Saline, MI Mastiff in Sylvania, OH Mastiff in Tecumseh, MI Mastiff in Toledo, OH Mastiff in Waterville, OH Mastiff in Wauseon, OH Mastiff in Ypsilanti, MI

Related breeds in Adrian, Michigan

Bullmastiffs in Adrian, Michigan Neapolitan Mastiffs in Adrian, Michigan Saint Bernards in Adrian, Michigan

Mastiff shelters & rescues in Adrian, Michigan

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Adrian, Michigan. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

33.3 miles

Humane Society of Huron Valley

3100 Cherry Hill Rd, Ann Arbor, MI 48105

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

More an arrow icon

Shelter

34.4 miles

Friends of Michigan Animals Rescue

51299 Arkona, Belleville, MI 48111

Pet Types: cats, dogs

More an arrow icon

Rescue

34.7 miles

Toledo's PET Bull Project

PO Box 167584, Toledo, OH 43616

Pet Types: dogs

More an arrow icon

Rescue

35.8 miles

The Buster Foundation Pit Bull Rescue

PO Box 233, Belleville, MI 48112

Pet Types: dogs

More an arrow icon

Shelter

37.8 miles

Humane Society of Monroe County

833 N. Telegraph Road, Monroe, MI 48162

Pet Types: cats, dogs

More an arrow icon

Rescue

46.2 miles

Focus on Cumberland County Animal Safety-MI Transport Stop

Taylor, MI 48180

Pet Types: cats, dogs

More an arrow icon

Rescue

48.8 miles

Last Day Dog Rescue

Last Day Dog Rescue, P.O. Box 51935, Livonia, MI 48151

Pet Types: cats, dogs

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

clipboard with list

Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

Learn More an arrow icon