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Mastiff puppies and dogs in Clinton, South Carolina

Looking for a Mastiff puppy or dog in Clinton, South Carolina? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Clinton, South Carolina Other pups in Clinton, South Carolina Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Clinton, South Carolina Mastiff shelters and rescues in Clinton, South Carolina Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Clinton, South Carolina

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Clinton, South Carolina

These Mastiffs are available for adoption close to Clinton, South Carolina.
We'll also keep you updated on Charlie Brown's adoption status with email updates.
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Charlie Brown

Mastiff

Male, 7 yrs 9 mos
Irmo, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Charlie Brown is a lovable Mastiff mix who is in search of a forever home. This boy is truly a gentle giant. Despite being found abandoned when his previous owners moved away, Charlie Brown has shown immense resilience and is healing beautifully from his past environment.He`s as calm as they come. He has a serene demeanor that makes him an ideal companion for any household. Whether it’s young children, other dogs, or even cats, Charlie Brown gets along with everyone! What desires most is human companionship. Charlie`s knees are a bit achy so he is on a good join supplement. If you`re looking for a running partner, CB isn`t the right pup for you. He`d love nothing more than to be your couch potato buddy, offering warmth and love in exchange for a cozy spot by your side. 6 yrs 90 lb. Neuter, vaccines, microchip provided.

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We'll also keep you updated on Emily's adoption status with email updates.
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Emily

Mastiff Mixed Breed (Medium)

Female, 3 yrs 9 mos
Lexington, SC
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Adopt Emily! 🐾 Emily is a 3 y/o mastiff mix of medium build. She is lower energy and loves to cuddle. While Emily is dog social, she prefers laid back non playful dogs who meet her same energy. She was very undersocialized and it’s hard to say if she ever lived in a home prior to her foster home. She prefers a quiet home where she can feel safe and relax. She struggled with fear more in the beginning than now. She is being fostered by a professional dog trainer so she has come a long way. She did well with her housemate that recently passed away. That has caused her a little anxiety as she misses her very much. 😔 Emily came into Columbia Animal Services as a stray. She was terrified in her kennel and at risk of euthanasia, so the behavior specialist decided to take her home to foster. ♥️ Emily has been well mannered and polite in her foster home and has enjoyed lounging, eating, playing, and doing enrichment activities. Emily’s adoption comes with free behavior coaching services from Columbia K9 training and behavior! 👍 She is about 40 pounds, medium build, spayed, microchipped and fully vetted. She required eye surgery that was done and she has completely healed. She is the perfect lap dog.

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We'll also keep you updated on Nala's adoption status with email updates.
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Nala

Mastiff Labrador Retriever

Female, Young
Blacksburg, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
Meet Nala! Breed: mastiff/lab mix. Age: est 4 years, est birthdate 1/22/2021 Weight: approx 65ish lbs. Training: leash, crate and housetrained. She also knows sit and down and eager to learn more. She is very food motivated which is a plus! Good with other dogs/cats? Yes to dogs, but no cats. Good with adults/kids? Nala is very loyal but it's takes her a little bit to warm up to new people. She is protective of her people. She is great with kids, however we feel she would do best in a home without many visitors, or the ability to put her up when you have company. Personality: shy/reserved in New situations. She is playful but also loves to cuddle. Nala is very loyal and protective of the people she loves. She loves to play with other dogs. She LOVES water. Nala is spayed, microchipped, heartworm negative & current on vaccinations and preventatives. If interested in adding Nala to your family, please message for an adoption application! Adoption fee: $75September 28, 2025, 7:06 pm

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We'll also keep you updated on Bear's adoption status with email updates.
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Bear

Mastiff

Female, 10 yrs 2 mos
Anderson, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Meet Bear! Bear is a 10 year old Mastiff mix. Bear is looking for a forever cuddle buddy.Some fun facts about Bear :Profession : Ultimate cuddle bugFavorite hobby : Stealing your heartFavorite song : Forever youngStop by and ask about Bear at Anderson Paws from 12pm to 5pm on M,T,TH,F,SA!

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Clinton, South Carolina.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Fountain Inn, SC Mastiff in Greenwood, SC Mastiff in Laurens, SC Mastiff in Mauldin, SC Mastiff in Newberry, SC Mastiff in Simpsonville, SC Mastiff in Spartanburg, SC Mastiff in Union, SC

Related breeds in Clinton, South Carolina

Bullmastiffs in Clinton, South Carolina Neapolitan Mastiffs in Clinton, South Carolina Saint Bernards in Clinton, South Carolina

Mastiff shelters & rescues in Clinton, South Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Clinton, South Carolina. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

45.7 miles

Homeward Bound Pet Rescue

PO Box 4335, Irmo, SC 29063

Pet Types: dogs

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Rescue

48.7 miles

We Are Zeus Inc

PO BOX 1851, Lexington, SC 29072

Pet Types: cats, dogs

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Shelter

49.4 miles

Anderson County PAWS

1320 Hwy 29 South, Anderson, SC 29626

Pet Types: cats, dogs, rabbits, small animals

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Rescue

49.8 miles

Mercy Rescue Haven

Blacksburg, SC 29702

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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