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Mastiff puppies and dogs in South Carolina

Looking for a Mastiff puppy or dog in South Carolina? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in South Carolina

Below are our newest added Mastiffs available for adoption in South Carolina. To see more adoptable Mastiffs in South Carolina, use the search tool below to enter specific criteria!
Photo of Delilah

Delilah

Mastiff

Female, Adult
Anderson, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
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Photo of Cage and Niambi

Cage and Niambi

Mastiff/Mastiff

Male, Adult
Pinewood, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Cage is a five year old boer boel. His color is black with a white chest. I have had him and his sister, Niambi since they were 8 weeks. They are very active, love to run outside, especially when it's not hot😊, they love to be pet ( big puppies) is what I call them, he was born the runt out of a litter of 15, now he is the biggest out of all of them. They just want to be loved......alot!!
Photo of Reece

Reece

English Mastiff

Female, Adult
York, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained,
Story
Meet Reece!  At a little over a year old, this gentle giant is a doll here at the rescue. She was a little confused when she first came to us, but very quickly became a big baby. She is friendly with the people here but tends to get closer with the men. She is crate trained, leash trained, and house trained. She does okay with the other dogs here, she just wants all of your attention. She is very treat motivated, and does know basic commands. Reece would do best in a home with older children, as she is a big girl weighing 91 pounds. She has been spayed, all of her shots are up to date , she is microchipped, and ready to be a part of a family. If you just need a big baby to lay around on the couch with, a partner in crime, or a walking buddy, Reece is your girl. Please fill out an adoption application at Richardsonrescue.org, and make this girl apart of your family. Visit this organization's web site to see any additional information available about this pet.September 30, 2023, 11:04 am
Photo of Nala

Nala

Mastiff/Labrador Retriever

Female, Young
Blacksburg, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained,
Story
Meet Nala! Breed: mastiff/lab mix. Age: est 2.5 years, est birthdate 1/22/2021 Weight: approx 65ish lbs. Training: leash, crate and housetrained. She also knows sit and down and eager to learn more. She is very food motivated which is a plus! Good with other dogs/cats? Yes to dogs, but no cats. Good with adults/kids? Nala is very loyal but it's takes her a little bit to warm up to you. She prefers women but will accept a man. It takes her a bit to warm up to strangers. She is fostered with kids and does great. Personality: shy/reserved in New situations, warms up to be friendly & playful. She loves to play with other dogs. She seems to like to play in water. Reason for rescue: Nala came in as a pup with siblings. She has been adopted and returned twice. First time- she chewed up things when left unattended. Second time - owner was unable to provide time and care she needed. Nala is looking for someone to give her heart to. She is very loyal but it takes her a little time to trust - can you blame her? She prefers women but does fine with her foster dad. She is fearful of most men. She crates easily and walks well on a leash. She does well with the 3 kids in her foster home. She loves to play with her 4-legged foster brother. Nala is spayed, microchipped, heartworm negative & current on vaccinations and preventatives. If interested in adding this sweet baby to your family, please message for an adoption application! Adoption fee: $75September 29, 2023, 11:12 pm
Photo of Scooby

Scooby

Mastiff

Male, Adult
Spartanburg, SC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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Photo of Bronson

Bronson

Mastiff/Boxer

Male, Adult
McCormick, SC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Shots are up-to-date,
Story
Meet Bronson. This big boy just wants to be loved. He enjoys chewing on squeaky toys and being pet, especially his ears. If you stop, he will give you a paw to let you know you weren’t finished. Bronson came in with very little fur due to an ongoing case of mange. His skin has healed, and his fur is slowly starting to grow back. He seems to be good with other dogs, and even had a 20lb roommate at the shelter for several weeks until he was adopted. Bronson is very food motivated and is most likely house trained. He was born on 3/2/21 so he is full grown at 80lbs. We believe he is a mastiff mix and he is up to date on his shots, microchipped, and neutered. If you are looking for a cuddle companion this winter, Bronson may be for you. *************************************************************************** This pet comes with an implanted 24 PetWatch microchip and free registration into the 24PetWatch pet recovery service. *************************************************************************** This dog is available for adoption at the Humane Society of McCormick County is SC for an adoption fee. All of our dogs are indoor dogs with outdoor privileges. To adopt, contact 864-391-2349 or HSMC2000@gmail.com. We are an all-volunteer 501c3 organization. To learn more, visit www.mccormickcounty.petfinder.com.September 28, 2023, 10:53 am

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in South Carolina.

Mastiff puppies and dogs in South Carolina cities

Mastiff shelters & rescues in South Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in South Carolina. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Richardson Rescue

1968 Garvin Road, York , SC 29745

Pet Types: cats, dogs

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Shelter

Humane Society of McCormick County, Inc.

PO Box 900, McCormick , SC 29835

Pet Types: cats, dogs

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Rescue

Mercy Rescue Haven

Blacksburg , SC 29702

Pet Types: cats, dogs

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Shelter

Spartanburg Humane Society

150 Dexter Road, Spartanburg , SC 29303

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

Anderson County PAWS

1320 Hwy 29 South, Anderson , SC 29626

Pet Types: cats, dogs, rabbits, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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