Mastiff Puppies and Dogs in South Carolina

Adopt a Mastiff near you in South Carolina

Below are our newest added Mastiffs available for adoption in South Carolina. To see more adoptable Mastiffs in South Carolina, use the search tool below to enter specific criteria!

Moose

Mastiff/Mutt

Male, Adult

Spartanburg, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

Moose is super sweet, loves to cuddle. I adopted him from a shelter but unfortunately have infant children and am no longer able to care for him. He’s great with female dogs but not so much males. He can tolerate cats. He likes kids toddler age and above. Free to a good home. I don’t want him to go back to a shelter.

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Zeus

Mastiff/Labrador Retriever

Male, Young

Honea Path, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Not good with kids, Good with dogs, Good with cats, Needs experienced adopter,

Story

He is a super sweet dog who loves cuddles but is in need of a yard because apartment life isn’t for him. He is one year old and full energy. He was house broken but due to having to relocate from a house with a yard to an apartment we have taken some steps back. He is friendly with other animals but plays a bit on the rougher side with other dogs. He will be rehomed with food, bowls, crate, toys, clothes, harness, and leash.

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Nala

Mastiff/Labrador Retriever

Female, Young

Blacksburg, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Not good with cats, House-trained,

Story

Meet Nala! Breed: mastiff/lab mix. Age: est 2.5 years, est birthdate 1/22/2021 Weight: approx 65ish lbs. Training: leash, crate and housetrained. She also knows sit and down and eager to learn more. She is very food motivated which is a plus! Good with other dogs/cats? Yes to dogs, but no cats. Good with adults/kids? Nala is very loyal but it's takes her a little bit to warm up to you. She prefers women but will accept a man. It takes her a bit to warm up to strangers. She is fostered with kids and does great. Personality: shy/reserved in New situations, warms up to be friendly & playful. She loves to play with other dogs. She seems to like to play in water. Reason for rescue: Nala came in as a pup with siblings. She has been adopted and returned twice. First time- she chewed up things when left unattended. Second time - owner was unable to provide time and care she needed. Nala is looking for someone to give her heart to. She is very loyal but it takes her a little time to trust - can you blame her? She prefers women but does fine with her foster dad. She is fearful of most men. She crates easily and walks well on a leash. She does well with the 3 kids in her foster home. She loves to play with her 4-legged foster brother. Nala is spayed, microchipped, heartworm negative & current on vaccinations and preventatives. If interested in adding this sweet baby to your family, please message for an adoption application! Adoption fee: $75April 23, 2024, 11:22 am

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Brutus

Mastiff

Male, Adult

Moncks Corner, SC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in South Carolina.

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Adopt a Mastiff near you in South Carolina

Below are our newest added Mastiffs available for adoption in South Carolina. To see more adoptable Mastiffs in South Carolina, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog