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Neapolitan Mastiff puppies and dogs in San Diego, California

Looking for a Neapolitan Mastiff puppy or dog in San Diego, California? Adopt a Pet can help you find an adorable Neapolitan Mastiff near you.

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Adopt a Neapolitan Mastiff near you Neapolitan Mastiff in cities near San Diego, California Other pups in San Diego, California Search for a Neapolitan Mastiff puppy or dog near you Browse Neapolitan Mastiff puppies and dogs in nearby cities Browse related breeds in San Diego, California Neapolitan Mastiff shelters and rescues in San Diego, California Learn more about adopting a Neapolitan Mastiff puppy or dog

Adopt a Neapolitan Mastiff near you in San Diego, California

These Neapolitan Mastiffs are available in San Diego, California.
We'll also keep you updated on Leo's adoption status with email updates.
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Leo

Neapolitan Mastiff

Male, Adult
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Not good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Leo is a gorgeous neapolitan mastiff.  His ideal home would be a home with someone who knows the breed and can set boundaries for him to thrive. He has the potential to do well with other dogs as long as the other dogs have good temperament. He was fostered with kids who were 12 years of age and he did good with them. Come meet sweet Leo if you are looking for a gorgeous large boy. Leo's adoption comes with training. June 2, 2025, 11:00 pm

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Or, how about these Neapolitan Mastiffs in cities near San Diego, California

These Neapolitan Mastiffs are available for adoption close to San Diego, California.
We'll also keep you updated on Leo's adoption status with email updates.
Photo of Leo

Leo

Neapolitan Mastiff

Male, Adult
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Not good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Leo is a gorgeous neapolitan mastiff.  His ideal home would be a home with someone who knows the breed and can set boundaries for him to thrive. He has the potential to do well with other dogs as long as the other dogs have good temperament. He was fostered with kids who were 12 years of age and he did good with them. Come meet sweet Leo if you are looking for a gorgeous large boy. Leo's adoption comes with training. June 2, 2025, 11:00 pm

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We'll also keep you updated on Mint's adoption status with email updates.
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Mint

Neapolitan Mastiff Mastiff

Female, Young
La Mesa, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Not good with cats, Needs experienced adopter, Shots are up-to-date,
Story
Our dogs had an accidental litter with 11 puppies born 3/1/24 and we did our best to find good homes for all of them. Unfortunately, we were unable to find Mint a forever home before she grew out of the puppy stage. We decided to keep her, but female Neapolitan mastiffs rarely get along and that is the case with Mint and her mom. They have to be kept completely separate and it has caused Mint to not receive the love and attention she deserves. Mint gets along with 2 of our male dogs but not 1 that also has a reactive personality. With training she will be an amazing guardian as she definitely has the intensity of the Neapolitan mastiffs. But, we caution having her around other dogs. She loves her people family and is so excited to see us. She is good with our kids and grandkids. She is wary of strangers and will growl, so please be prepared for a slow warm up when you meet her. She is crate trained. She really Is the sweetest girl that deserves a lot of attention and a forever family!

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We'll also keep you updated on Napoleon's adoption status with email updates.
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Napoleon

Neapolitan Mastiff American Bulldog

Male, Adult
Vista, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
Great dog, can’t keep due to having a baby.

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We'll also keep you updated on Fiona's adoption status with email updates.
Photo of Fiona

Fiona

Neapolitan Mastiff

Female, Adult
Riverside, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Meet Fiona 💕 Fiona is a beautiful Neapolitan Mastiff estimated to be around 3 years old. It’s very clear that she was used extensively for breeding before coming to us, and despite everything she’s been through, she is nothing short of incredible. She is incredibly sweet, gentle, and affectionate. Fiona has a playful side but is overall a super chill, easygoing girl who truly loves the simple things like cuddling, belly rubs, and being close to her people. She has the kindest soul and a very soft presence. Fiona is non-reactive and tolerant around other dogs, but she would do best as the only dog in the home. Due to the heavy facial folds common in her breed, her vision is not the best, so fast-moving dogs, especially during playful moments can sometimes startle her. She does have severe hip dysplasia, likely a result of being bred repeatedly, and she will need a home that understands and can manage her orthopedic needs. When Fiona arrived, she was very underweight, but with proper care and nutrition, she is slowly and steadily putting healthy weight back on. We are looking for a home with mastiff or giant breed experience, someone who understands her structure, limitations, and the special care she deserves. One of the sweetest things about Fiona? Sometimes she sings and it is absolutely adorable. Fiona has so much love to give and deserves a calm, understanding home where she can finally just be a dog, loved, safe, and cherished by her humans. If interested in meeting Fiona, please apply on our website today! https://www.underdogheroes.org/applytoadopt

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We'll also keep you updated on Fiona's adoption status with email updates.
Photo of Fiona

Fiona

Neapolitan Mastiff

Female, Adult
Riverside, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Meet Fiona 💕 Fiona is a beautiful Neapolitan Mastiff estimated to be around 3 years old. It’s very clear that she was used extensively for breeding before coming to us, and despite everything she’s been through, she is nothing short of incredible. She is incredibly sweet, gentle, and affectionate. Fiona has a playful side but is overall a super chill, easygoing girl who truly loves the simple things like cuddling, belly rubs, and being close to her people. She has the kindest soul and a very soft presence. Fiona is non-reactive and tolerant around other dogs, but she would do best as the only dog in the home. Due to the heavy facial folds common in her breed, her vision is not the best, so fast-moving dogs, especially during playful moments can sometimes startle her. She does have severe hip dysplasia, likely a result of being bred repeatedly, and she will need a home that understands and can manage her orthopedic needs. When Fiona arrived, she was very underweight, but with proper care and nutrition, she is slowly and steadily putting healthy weight back on. We are looking for a home with mastiff or giant breed experience, someone who understands her structure, limitations, and the special care she deserves. One of the sweetest things about Fiona? Sometimes she sings and it is absolutely adorable. Fiona has so much love to give and deserves a calm, understanding home where she can finally just be a dog, loved, safe, and cherished by her humans. If interested in meeting Fiona, please apply on our website today! https://www.underdogheroes.org/applytoadopt

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These pups are in San Diego, California too!

Below are our newest added Neapolitan Mastiffs available for adoption in San Diego, California. To see more adoptable Neapolitan Mastiffs in San Diego, California, use the search tool below to enter specific criteria!
We'll also keep you updated on Hippo's adoption status with email updates.
Special Needs
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Hippo

Bullmastiff

Male, Adult
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Needs special attention, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Age: 6 years old Gender: Male Breed: Bull Mastiff mix Weight: 84 lbs Personality: Very sweet and cuddly! He is very pleasant to walk if there are no other dogs in the area. He is learning to be more confident and less reactive. Education: Good with bathroom and leash training and is working on leash reactivity Favorite Activities: Tug of war, long night walks, hanging out in the kitchen Looking for: An active family who will love him and play with him! Some patient training will help him be the best boy ever! He will do best as an only dog right now. Hippo likes routine so someone who can create some structure for him would be ideal to help with his anxiety! A family with kids would be good, too - he has been great with kids of all ages, even with toddlers! A home with a backyard in a quiet neighborhood would be great! Special needs: Current medication to help with separation anxiety Prozac (fluoxetine) (~$5.00). Monthly cost depending on where purchased and market value. Adoption Fee: $ 250 ##1733826##

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We'll also keep you updated on Da Right's adoption status with email updates.
Photo of Da Right

Da Right

Great Dane American Bulldog

Male, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by our Humane Law Enforcement. Why Da Right might be the Right one for you: Da Right has not had it easy and it is going to take a special person to make things Right for Da Right. Da Right wants to know that he is doing the right thing. He wants to be told when he is a good boy. He is social with people (not other dogs) and very food motivated so training should come easy and naturally with Da Right. We can help you with positive reinforcement training techniques that will build Da Rights confidence and encourage good behaviors. He wants (needs) to be the only dog in the home and best if he is the only pet. He wants to be the focus of attention, care and play. He will want lots of playtime. He will be best in a quiet home with low traffic. He will benefit from a clear routine and enrichment schedule that he can depend on. Do you want to take on a needy dog who has not had a great start in life and give him the love and care he deserves and wants? He is ready for a new life. He will try his hardest to make you proud of him. At SDHS:Da Right has been vaccinated, microchipped and spayed neutered. Da Right is now ready for his new home! Primary Color: White Secondary Color: Black Weight: 90 Age: 4yrs 2mths 1wks

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We'll also keep you updated on Da Left's adoption status with email updates.
Photo of Da Left

Da Left

Great Dane American Bulldog

Male, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: Da Left was brought in by our Humane Law Enforcement. Why Da Left might be the right dog for you: Da Left with his one white ear and one black ear is a special dog and will want a special person to show him what life is like as someone's good dog in a warm and caring home. Da Left has not had a lot of positive reinforcement in his life and he wants to be told when he is a good boy. He is social with people (not other dogs) and very food motivated so training should come easy and naturally with Da Left. We can help you with positive reinforcement training techniques that will build Da Left's confidence and encourage good behaviors. He wants (needs) to be the only dog in the home and best if he is the only pet. He wants to be the focus of attention, care and play. He will want lots of playtime. He will be best in a quiet home with low traffic. He will benefit from a clear routine and enrichment schedule that he can depend on. Do you want to take on a needy dog who has not had a great start in life and give him the love and care he deserves and wants? He is ready for a new life. He will try his hardest to make you proud of him. At SDHS:Da Left has been vaccinated, microchipped and spayed neutered. Da Left is now ready for his new home! Primary Color: White Secondary Color: Black Weight: 89.5 Age: 4yrs 2mths 1wks

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Search for a Neapolitan Mastiff puppy or dog

Use the search tool below to browse adoptable Neapolitan Mastiff puppies and adults Neapolitan Mastiff in San Diego, California.

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Neapolitan Mastiff puppies and dogs in nearby cities

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Related breeds in San Diego, California

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Neapolitan Mastiff shelters & rescues in San Diego, California

There are animal shelters and rescues that focus specifically on finding great homes for Neapolitan Mastiff puppies in San Diego, California. Browse these Neapolitan Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

3.6 miles

The Heroic Tail

San Diego, CA 92116

Pet Types: dogs

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Rescue

32.8 miles

Underdog Heroes

Riverside, CA 92058

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Neapolitan Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Neapolitan Mastiff puppy. Check out the links below for everything you ever wanted to know about Neapolitan Mastiff puppies and adults.

Neapolitan Mastiff basics

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Where do Neapolitan Mastiffs come from? How many types of Neapolitan Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Neapolitan Mastiff.

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