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Great Dane puppies and dogs in Saint Louis, Missouri

Looking for a Great Dane puppy or dog in Saint Louis, Missouri? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Saint Louis, Missouri

These Great Danes are available in Saint Louis, Missouri.
We'll also keep you updated on Fred's adoption status with email updates.
Photo of Fred

Fred

Great Dane

Male, 2 yrs 7 mos
St. Louis, MO
Size
(when grown) -
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hey! I'm Fred. I'm a 2.5 year old Great Dane mix with a fun personality. I'm a bit of a goofball- typical for most Danes. I seem to do good with other dogs and recently became the father to 7 little pups. Thankfully, my parenting days are done and over with. I'm hoping for a loving family to take me home. If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to reserve me for an appointment. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2565696##

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We'll also keep you updated on Panda's adoption status with email updates.
Photo of Panda

Panda

Great Dane Boxer

Male, 2 yrs 2 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
WE ARE A TX-BASED RESCUE. THIS DOG IS CURRENTLY LOCATED IN TX AND WILL BE TRANSPORTED UPON ADOPTION. Please fill out an adoption application at haydudeequine.org 🐾 Pleased to meet you - I’m Panda! 🐾 Part marshmallow, part zoomie machine, and 100% good boy. I came in on the skinnier side (hey, rescue life isn’t exactly a buffet), but I’m filling out nicely thanks to regular meals, snacks and love... lots and lots of love!! At 2yrs and 70lbs I’m already the total package: housebroken, crate trained, and doggy-door certified. I love people of all sizes, though my big, playful energy is better matched with bigger kids and medium-to-large doggie siblings. Small pups might find my enthusiasm a little…extra. But don’t worry—I’m a gentleman and happily back off if another dog says “nah, bro.” (Even Chad’s grumpy old pit bull approves.) My hobbies? Oh, just the usual—water splashing, toy stealing (ahem…sharing), and epic backyard zoomies. I walk like a dream on leash and would love to be your partner for strolls, hikes, or jogs. Underneath all the silliness, I’m a soft-hearted guy who just wants a family to call my own. Someone to laugh at my antics, throw my toys, and remind me every day that I’m finally home. 🖤🤍 Apply today at haydudeequine.org and get ready to add a little Panda-monium to your life. I promise it comes with lots and lots of cherished moments and unlimited cuddles!!!

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We'll also keep you updated on Ghost's adoption status with email updates.
Photo of Ghost

Ghost

Great Dane

Male, 1 yr
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Ghost 👻 Ghost is a loving, playful, and downright charming pup who brings a sweet mix of goofiness and affection everywhere he goes. His foster mom says he has this adorable habit of “cat-rubbing” on your legs—he’ll gently lean or wiggle against you just like a cat asking for love. It’s impossible not to smile when he does it. This boy is still very much a puppy at heart. He loves to play, plop himself right onto your feet, and even sit on his dog friends’ faces mid-playtime (they don’t seem to mind—he’s just being Ghost!). He soaks up attention, enjoys being close, and always finds a way to sneak in a cuddle. Ghost is amazing with other dogs and great with kids. He’s also been around horses and ducks and does wonderfully with them too! His gentle spirit really shines around all kinds of animals. He can be a little skittish with loud noises, but his reaction is just to duck his head and trot to his kennel for a sense of safety. With reassurance and consistency, he’ll continue growing more confident. Ghost is sweet, funny, social, and full of love—everything you could want in a companion. He’s ready to bring joy, laughter, and loyalty to a forever family of his very own. https://new.shelterluv.com/matchme/adopt/NASD/Dog

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We'll also keep you updated on Costa's adoption status with email updates.
Photo of Costa

Costa

Great Dane

Male, 6 yrs
St. Louis, MO
Size
(when grown) -
Details
-
Story
-

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We'll also keep you updated on Misty AK's adoption status with email updates.
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Misty AK

Great Dane Labrador Retriever

Female, 2 yrs 10 mos
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Meet Misty! She's a smart lady who is smart as a whip! She's crate trained, mastered many commands (sit, down, off, mat, enough, go to your room, here, all done- more than most kids :). She loves to run, play fetch and be wherever you are! She's a year and a half old, and was lucky enough to have professional training donated to help her find her forever home. Whoever adopts her will receive at least one free hand off session from her trainer to help her transition go perfectly! Her ideal family would be somewhat active (she needs to run around a yard at least a few times per day). She gets along well with other dogs, but calmer dogs are best. Misty loves to play, but she can get very excited if the other dog is too energetic! She would do well with older children. Younger children and cats would require a lot of supervision. Her trainer thinks she would be a great agility dog, but she is smart enough to do anything you want to train her to do! She will require some active parenting to teach her the rules of your house, because she is so smart, she may try to make her own activities if nothing fun is provided! She's potty trained now (we had some overnight accidents until she started going in her crate at night). She's a great dog with a good head on her shoulders, and she wants to know if you are the one for her! $200 In State Adoption Fee (in Texas) $400 Out of State Fee (includes Transportation to your area) $50 Temporary fuel surcharge.

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Or, how about these Great Danes in cities near Saint Louis, Missouri

These Great Danes are available for adoption close to Saint Louis, Missouri.
We'll also keep you updated on Fred's adoption status with email updates.
Photo of Fred

Fred

Great Dane

Male, 2 yrs 7 mos
St. Louis, MO
Size
(when grown) -
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hey! I'm Fred. I'm a 2.5 year old Great Dane mix with a fun personality. I'm a bit of a goofball- typical for most Danes. I seem to do good with other dogs and recently became the father to 7 little pups. Thankfully, my parenting days are done and over with. I'm hoping for a loving family to take me home. If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to reserve me for an appointment. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2565696##

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We'll also keep you updated on Panda's adoption status with email updates.
Photo of Panda

Panda

Great Dane Boxer

Male, 2 yrs 2 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
WE ARE A TX-BASED RESCUE. THIS DOG IS CURRENTLY LOCATED IN TX AND WILL BE TRANSPORTED UPON ADOPTION. Please fill out an adoption application at haydudeequine.org 🐾 Pleased to meet you - I’m Panda! 🐾 Part marshmallow, part zoomie machine, and 100% good boy. I came in on the skinnier side (hey, rescue life isn’t exactly a buffet), but I’m filling out nicely thanks to regular meals, snacks and love... lots and lots of love!! At 2yrs and 70lbs I’m already the total package: housebroken, crate trained, and doggy-door certified. I love people of all sizes, though my big, playful energy is better matched with bigger kids and medium-to-large doggie siblings. Small pups might find my enthusiasm a little…extra. But don’t worry—I’m a gentleman and happily back off if another dog says “nah, bro.” (Even Chad’s grumpy old pit bull approves.) My hobbies? Oh, just the usual—water splashing, toy stealing (ahem…sharing), and epic backyard zoomies. I walk like a dream on leash and would love to be your partner for strolls, hikes, or jogs. Underneath all the silliness, I’m a soft-hearted guy who just wants a family to call my own. Someone to laugh at my antics, throw my toys, and remind me every day that I’m finally home. 🖤🤍 Apply today at haydudeequine.org and get ready to add a little Panda-monium to your life. I promise it comes with lots and lots of cherished moments and unlimited cuddles!!!

Learn More

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We'll also keep you updated on Ghost's adoption status with email updates.
Photo of Ghost

Ghost

Great Dane

Male, 1 yr
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Ghost 👻 Ghost is a loving, playful, and downright charming pup who brings a sweet mix of goofiness and affection everywhere he goes. His foster mom says he has this adorable habit of “cat-rubbing” on your legs—he’ll gently lean or wiggle against you just like a cat asking for love. It’s impossible not to smile when he does it. This boy is still very much a puppy at heart. He loves to play, plop himself right onto your feet, and even sit on his dog friends’ faces mid-playtime (they don’t seem to mind—he’s just being Ghost!). He soaks up attention, enjoys being close, and always finds a way to sneak in a cuddle. Ghost is amazing with other dogs and great with kids. He’s also been around horses and ducks and does wonderfully with them too! His gentle spirit really shines around all kinds of animals. He can be a little skittish with loud noises, but his reaction is just to duck his head and trot to his kennel for a sense of safety. With reassurance and consistency, he’ll continue growing more confident. Ghost is sweet, funny, social, and full of love—everything you could want in a companion. He’s ready to bring joy, laughter, and loyalty to a forever family of his very own. https://new.shelterluv.com/matchme/adopt/NASD/Dog

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We'll also keep you updated on Costa's adoption status with email updates.
Photo of Costa

Costa

Great Dane

Male, 6 yrs
St. Louis, MO
Size
(when grown) -
Details
-
Story
-

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We'll also keep you updated on Misty AK's adoption status with email updates.
Photo of Misty AK

Misty AK

Great Dane Labrador Retriever

Female, 2 yrs 10 mos
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Meet Misty! She's a smart lady who is smart as a whip! She's crate trained, mastered many commands (sit, down, off, mat, enough, go to your room, here, all done- more than most kids :). She loves to run, play fetch and be wherever you are! She's a year and a half old, and was lucky enough to have professional training donated to help her find her forever home. Whoever adopts her will receive at least one free hand off session from her trainer to help her transition go perfectly! Her ideal family would be somewhat active (she needs to run around a yard at least a few times per day). She gets along well with other dogs, but calmer dogs are best. Misty loves to play, but she can get very excited if the other dog is too energetic! She would do well with older children. Younger children and cats would require a lot of supervision. Her trainer thinks she would be a great agility dog, but she is smart enough to do anything you want to train her to do! She will require some active parenting to teach her the rules of your house, because she is so smart, she may try to make her own activities if nothing fun is provided! She's potty trained now (we had some overnight accidents until she started going in her crate at night). She's a great dog with a good head on her shoulders, and she wants to know if you are the one for her! $200 In State Adoption Fee (in Texas) $400 Out of State Fee (includes Transportation to your area) $50 Temporary fuel surcharge.

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We'll also keep you updated on Foster Homes Needed's adoption status with email updates.
Photo of Foster Homes Needed

Foster Homes Needed

Great Dane

Male, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats,
Story
Please consider fostering a Great Dane. It will be the best decision you ever made. Please visit www.foreverfriendsgdri.com Thank you

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These pups are in Saint Louis, Missouri too!

Below are our newest added Great Danes available for adoption in Saint Louis, Missouri. To see more adoptable Great Danes in Saint Louis, Missouri, use the search tool below to enter specific criteria!
We'll also keep you updated on Mae's adoption status with email updates.
Photo of Mae

Mae

Bullmastiff

Female, Adult
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
BASICS: Bullmastiff / female / 5 years old CHILDREN: Yes CATS: Unknown DOGS: Male dogs over 30lbs, with slow introduction and supervision PERSONALITY: Medium energy level; Very sweet and affectionate; Enjoys taking naps in the sun or on the couch, exploring outdoors in the yard, walking the neighborhood and LOVES hanging out with people. Loves men! TRAINING: Housebroken, leash trained, knows basic obedience and how to use a dog door SPECIAL NEEDS: None VETTING: Fully vaccinated, spayed, microchipped Ready to give Mae the forever home of her dreams? Fill out our Adoption Application, located The Bullpen Way Station & Sanctuary under the 'work with us' tab. We highly recommend that our potential adopters fill out an online application as soon as possible, as it greatly expedites the process of finding the right dog for your situation. Our dogs are available for adoption nationwide but preference is given to adopters willing to do an in-person meeting. Please understand that our dogs are not adopted on a first-come, first-served basis, but rather we strive for a "perfect placement" so we know that they will not be failed again.

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We'll also keep you updated on Gambino's adoption status with email updates.
Photo of Gambino

Gambino

Bullmastiff Bull Terrier

Male, 6 yrs 5 mos
St. Louis, MO
Size
(when grown) -
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
Get ready to meet Gambino, a handsome dog with a heart of gold who is just waiting to become your devoted co-pilot in life! This middle-aged gentleman is proof that second chances are beautiful. Gambino has had a rough start, enduring a life chained up outside and then spending several months in a shelter kennel after his rescue. Thankfully, he has been safe in a foster home for the last few weeks, decompressing and learning what it means to be a cherished pet. Now, all he needs is a patient, loving person who can help his past trauma become a distant memory. Gambino is a truly dedicated lover boy, and his favorite place in the world is right by your side. He’s incredibly clingy because he views his person as the most important thing in the world, making him a naturally protective companion. He has a history of making friends easily with women and is simply looking for a confident, patient handler who can help him feel secure and show him the world is safe. He’s food and praise motivated, knows his basic commands, and he loves all the scratches, especially on his neck! He’s also a big fan of toys and chews—rope toys, squeakers, balls, chew bones, you name it, he likes it! Gambino is the total package when it comes to house manners. He is perfectly potty-trained and a star student in his kennel, heading to his crate easily with just a little help from a tasty frozen Kong. He’s a dream on the leash and responds perfectly to "sit" and "no." He would probably prefer a secure fenced-in yard where he can relax and enjoy his time outdoors, without the restriction of a leash. This guy thrives on routine and clear boundaries. Due to his history as a watchdog, he would likely thrive as the solo pet in the home. He's working hard on being a little more gentle with accepting treats (he still gets a little chomp-happy!) but shows great improvement with every new skill he learns. Gambino's ideal home is one where his person is ready for a shadow and a snuggle machine! He is a sweetheart who is just beginning to learn how wonderful life can be. If you're looking for a devoted, cuddly, and house-trained best friend who will make you feel loved and appreciated every single day, look no further than the charming Gambino!

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We'll also keep you updated on Kelly JuM/PF's adoption status with email updates.
Photo of Kelly JuM/PF

Kelly JuM/PF

Anatolian Shepherd Labrador Retriever

Female, 1 yr 9 mos
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Looking for a loyal companion who will shower you with love every single day? Allow us to introduce Kelly, a stunning girl with a heart full of affection and a spirit that lights up every room she enters. And SPEAKING of showers.... SHE LOVES THE WATER :) Kelly is a love bug through and through. One of her favorite things in the world is giving warm, gentle hugs. Lean in, and she’ll nestle right into you, as if to say, “You’re my person.” She absolutely adores being close to her humans, and there’s nothing she enjoys more than curling up beside you after a day full adventures. Scratches? Yes, please! Behind the ears, under the chin, or right at the base of her tail—Kelly is always up for a good scratch session, and she’ll reward you with the sweetest look of pure bliss. Kelly is the kind of dog who will quickly become your shadow—in the best way. She’s loyal, calm, and always eager to be part of the action, whether it’s a quiet evening at home or a walk around the neighborhood. She thrives on companionship and would do best in a home where she gets plenty of attention, affection, and quality time with her people. She's the perfect blend of affectionate and mellow—loving and eager to please. Kelly is ready to start her next chapter with someone who will cherish her as much as she’ll cherish them. In return, she promises endless cuddles, constant companionship, and unconditional love. Local adoption fee is $200 (in TX) Out of state adoption fee is $450 (includes transport to your area)

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Saint Louis, Missouri.

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Great Dane puppies and dogs in nearby cities

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Related breeds in Saint Louis, Missouri

Anatolian Shepherds in Saint Louis, Missouri Bullmastiffs in Saint Louis, Missouri Irish Wolfhounds in Saint Louis, Missouri

Great Dane shelters & rescues in Saint Louis, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Saint Louis, Missouri. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Shelter

1.8 miles

Polk County Humane Society - St. Louis Transport

10900 Sunset Hills Plaza, St. Louis, MO 63127

Pet Types: cats, dogs

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Rescue

6.8 miles

Hay Dude Critter Rescue - MO transport

St. Louis, MO 63111

Pet Types: cats, dogs, horses

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Rescue

8.9 miles

Nate and Snoops Dog House - Missouri Transport Stop

St. Louis, MO 63118

Pet Types: dogs

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Shelter

10.6 miles

CARE STL

2700 Walnut Place, St. Louis, MO 63103

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Rescue

10.9 miles

Gods Dogs Rescue of TX for St Louis Transport Stop

St Louis, MO 63146

Pet Types: dogs

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Rescue

11.3 miles

Forever Friends Great Dane Rescue - Missouri

St. Louis, MO 63017

Pet Types: dogs

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Shelter

11.9 miles

Helping Strays of Monroe County

4221 Hanover Rd., Columbia, IL 62236

Pet Types: cats, dogs

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Rescue

29.8 miles

Hope Animal Rescues

PO Box 397, Godfrey, IL 62035

Pet Types: dogs

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Shelter

48.1 miles

No Time to Spare Animal Rescue and Sanctuary

27933 Pendleton Lost Creek Rd, Warrenton, MO 63383

Pet Types: dogs, farm animals, horses

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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