Great Dane Adoption in De Soto, MO: Great Dane Puppies for Sale in De Soto, MO

Adopt a Great Dane near you in De Soto, Missouri

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near De Soto, Missouri

These Great Danes are available for adoption close to De Soto, Missouri.

Yogi

Great Dane Mixed Breed (Large)

Male, 1 yr 7 mos

Pacific, MO

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Spayed or Neutered,

Story

Meet Yogi 🐾 Yogi is a 1-year-old high energy boy with the biggest heart 🤎 He loves attention, playing, and being close to his people at all times. He does great with bigger kids and would thrive with an active family who can match his energy and give him lots of love. He can get a little anxious when away from his people because he bonds deeply and always wants to be part of the action. Yogi also has no idea how big he is, so expect lots of oversized cuddles, leaning on you, and goofy moments 😂 He’s still young, playful, and learning, but he’s incredibly loving and loyal. Yogi is looking for a forever home filled with patience, affection, and plenty of belly rubs and he’ll love his people with his whole heart in return.

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Violet

Great Dane

Female, Adult

St. Louis, MO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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Smokey

Great Dane

Female, Young

Belleville, IL

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Not good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Approx DOB January 2025. We adopted Smokey 6/13/2026, after she had spent six weeks with her breeders mom, as her original family could no longer handle her. She's very sweet, sometimes goofy, and mostly a couch potato. She does have bursts energy, and needs a good walk or two a day, or a few sessions playing in the backyard. We have a 5 YO Dane female, altered, and a 4 YO Dane male, unaltered; we've had them both since 8 weeks. They got along well for 7 weeks, until Smokey had issue w/our girl - big fight. Now both won't have anything to do with her; we have to keep them separated 24/7, which isn't good for anyone in the house. She bonded with me (mom) instantly. Think part of the aggression toward our girl was resource guarding me, and trying to become the dominant one. She became more comfortable with us over the weeks (good!) - more tail wagging, better appetite; perhaps trying to solidify her position here. She'll make a WONDERFUL only dog.

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Gunner

Labrador Retriever Great Dane

Male, 10 mos

St. Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

PLEASE NOTE! WE ARE A TEXAS BASED RESCUE. THIS DOG IS CURRENTLY IN TEXAS AND WILL BE TRANSPORTED TO YOUR STATE ONCE ADOPTED. Our app can be found at haydudeequine.org Hi there! I'm Gunner. I'm an 10-month-old pup weighing about 60 pounds, and I'm looking for a family who appreciates a dog with a big heart and an even bigger personality. I've been told I'm quite the conversationalist. Now, don't worry—I'm not a nonstop barker. I just like to share my thoughts. If you're talking, I'll probably have something to say about it. If dinner is running late, expect a few comments. If we're headed out on an adventure, you'll definitely hear my excitement. Some people call it sass; I call it excellent communication skills. When I'm not busy chatting, you'll probably find me in the water. I absolutely LOVE to swim, splash, and play. A pond, pool, creek, lake, sprinkler—if it's wet, I'm interested. Water is my happy place, and I'd love a family who enjoys outdoor adventures as much as I do. I'm a sweet, social guy who enjoys making new friends and being part of the action. At 60 pounds, I'm a sturdy pup, but I'm still young and excited to learn new things. Whether we're exploring the great outdoors, going for a walk, or relaxing at home, I'll be right by your side—offering companionship, loyalty, and the occasional opinion. If you're looking for a friendly, water-loving best friend who will keep you laughing and always be ready for the next adventure, I might be the perfect match. Hope to meet you soon! Love, Gunner

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Dante JuM

Pointer Great Dane

Male, 4 yrs 10 mos

St Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Spayed or Neutered,

Story

Meet Dante, the charismatic Great Dane/pointer mix with a captivating blend of rough-around-the-edges charm and a tender heart. Dante's exterior may give off an air of confidence, but deep within lies a soft and gentle soul. Just like the characteristics of his heritage, Dante is intelligent and alert, always ready to engage with the world around him. He possesses a unique blend of confidence and independence, which adds to his intriguing personality. While he may be a bit standoffish at first due to his exceptional intelligence and focused nature, once Dante warms up to you, he becomes a tail-wagging, people-loving companion who will shower you with affection. It is crucial for Dante to be socialized thoroughly, gradually introducing him to a wide variety of people and animals in a gentle and patient manner. By providing Dante with the love, patience, and guidance he needs, you have the opportunity to witness his transformation into a devoted and loyal companion. Adopt Dante today and unlock the layers of his beautiful character, as he fills your life with joy, companionship, and a unique kind of elegance that only he can provide. Local adoption fee is $300(in TX) Out of state adoption fee is $550 (includes transport to your area)

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Dainty

Cane Corso Great Dane

Female, 3 yrs

East ST Louis, IL

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Meet Dainty! She is new to our rescue and looking for a family to call her own! If you are interested in a meet and greet for adoption for Dainty, please fill out an application on our website at www.gatewaypets.org/adopt. If you are interested in learning more about Dainty or the adoption process at GPG, please email placement@gatewaypets.org All of our dogs and cats will be microchipped, spayed or neutered, and up-to-date on vaccinations at the time of adoption. For more photos of Dainty, follow us on Facebook Gateway Pet Guardians and Instagram @gatewaypets ... #gpgDainty. To view other adoptable pets from our shelter, please visit, www.gatewaypets.org/adopt. Gateway Pet Guardians is proud to offer a variety of mixed breed dogs available for adoption. However, please keep in mind that we rarely know the genetic background of the animals we rescue and, as such, we cannot guarantee the exact breed combinations found within this dog. Therefore, we do not know his/her actual genetic makeup. Just know that this dog is probably a variety of several different breeds that have combined to create one very amazing and unique animal.

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Great Dane puppies and dogs in De Soto, Missouri

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Great Dane puppies and dogs in De Soto, Missouri

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Adopt a Great Dane near you in De Soto, Missouri

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near De Soto, Missouri

These Great Danes are available for adoption close to De Soto, Missouri.

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in nearby cities

Related breeds in De Soto, Missouri

Great Dane shelters & rescues in De Soto, Missouri

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog?

Great Dane basics

Great Dane basics