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Great Dane puppies and dogs in Missouri

Looking for a Great Dane puppy or dog in Missouri? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane in Missouri Search for a Great Dane puppy or dog Great Dane puppies and dogs in Missouri cities Great Dane shelters and rescues in Missouri Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Missouri

Below are our newest added Great Danes available for adoption in Missouri. To see more adoptable Great Danes in Missouri, use the search tool below to enter specific criteria!
We'll also keep you updated on Benny JC's adoption status with email updates.
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Benny JC

Great Dane/Labrador Retriever

Male, 1 yr 6 mos
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
Benny is good with kids and other dogs. He is house trained and crate trained. He loves squeaky toys. He's joyful and playful--Benny is full of energy!

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We'll also keep you updated on Kobie's adoption status with email updates.
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Kobie

Great Dane

Male, Adult
Saint Charles, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
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We'll also keep you updated on Thor's adoption status with email updates.
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Thor

Great Dane

Male, Young
Springfield, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Thor is just a big ole baby he is almost 2 years old come may. He knows how to walk without a leash if you say his name he will come to you. He loves being all over the family and in everyone business, he is an attention hog real bad. He does great with other dogs and with kids as well. He is not very know of his size so around little kids he might try to lay on them or lean on them. He knows sit and paw and give me belly. He is an amazing dog I just don’t have enough time to be with him as much as I should. He loves to be outdoors as well and go on adventures and going to the lake or river or a hike and he does good in cars of any size as well.

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We'll also keep you updated on Holyfield's adoption status with email updates.
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Holyfield

Great Dane/Rottweiler

Male, Young
Ballwin, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained,
Story
Holyfield (After Evander Holyfield, a portion of his right ear was bitten off during his first weeks of life) is a very affectionate dog that loves attention. He was given back to me from his previous owner due to a medical condition of his owner's mother in-law. He has all of his shots up to date but has not been neutered yet. A home with a fenced back yard or a farm is a must (No apartments) and he has been eating Purina one large breed puppy chow for that last 3 weeks. I have his 3 siblings and the mother who is a Rottweiler. He'll be 1 year old on May 30th. I look forward to getting the right person/family their new best friend.

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We'll also keep you updated on DROOLBERT's adoption status with email updates.
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DROOLBERT

Great Dane

Male, 4 yrs
Maryland Heights, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
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We'll also keep you updated on Duke's adoption status with email updates.
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Duke

Great Dane

Male
Warrenton, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Meet Duke, a delightful canine companion residing at our local shelter. Duke's personality is a winning combination of sweetness and smarts, paired with a goofy charm that endears him to everyone he meets. His gentle nature makes him an excellent friend for children and adults alike, and his loyalty knows no bounds. Duke is also quite clever, mastering tricks and commands with ease. Adopting Duke means bringing home a forever friend who will fill your days with joy and laughter. He's ready to be part of a loving family!April 9, 2026, 1:49 am

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Missouri.

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Great Dane puppies and dogs in Missouri cities

Great Dane Puppies near me Great Dane in Arnold Great Dane in Aurora Great Dane in Ballwin Great Dane in Belton Great Dane in Berkeley Great Dane in Black Jack Great Dane in Blue Springs Great Dane in Bolivar Great Dane in Bonne Terre Great Dane in Boonville Great Dane in Bowling Green Great Dane in Branson Great Dane in Breckenridge Hills Great Dane in Brentwood Great Dane in Bridgeton Great Dane in Brookfield Great Dane in Butler Great Dane in Cameron Great Dane in Cape Girardeau Great Dane in Carl Junction Great Dane in Carthage Great Dane in Caruthersville Great Dane in Charleston Great Dane in Chesterfield Great Dane in Chillicothe Great Dane in Clayton Great Dane in Clinton Great Dane in Columbia Great Dane in Creve Coeur Great Dane in Crystal City Great Dane in Dardenne Prairie Great Dane in Desloge Great Dane in De Soto Great Dane in Des Peres Great Dane in Dexter Great Dane in Eldon Great Dane in Ellisville Great Dane in Eureka Great Dane in Excelsior Springs Great Dane in Farmington Great Dane in Ferguson Great Dane in Festus Great Dane in Florissant Great Dane in Fulton Great Dane in Gladstone Great Dane in Grain Valley Great Dane in Grandview Great Dane in Greenwood Great Dane in Hannibal Great Dane in Harrisonville Great Dane in Hazelwood Great Dane in Higginsville Great Dane in Independence Great Dane in Jackson Great Dane in Jefferson City Great Dane in Jennings Great Dane in Joplin Great Dane in Kansas City Great Dane in Kearney Great Dane in Kennett Great Dane in Kirksville Great Dane in Kirkwood Great Dane in Lake St Louis Great Dane in Lamar Great Dane in Lebanon Great Dane in Lees Summit Great Dane in Lexington Great Dane in Liberty Great Dane in Macon Great Dane in Malden Great Dane in Manchester Great Dane in Maplewood Great Dane in Marshall Great Dane in Marshfield Great Dane in Maryland Heights Great Dane in Maryville Great Dane in Mexico Great Dane in Moberly Great Dane in Monett Great Dane in Mountain Grove Great Dane in Mount Vernon Great Dane in Neosho Great Dane in Nevada Great Dane in Nixa Great Dane in Normandy Great Dane in North Kansas City Great Dane in Oak Grove Great Dane in Odessa Great Dane in O Fallon Great Dane in Olivette Great Dane in Osage Beach Great Dane in Overland Great Dane in Ozark Great Dane in Pacific Great Dane in Park Hills Great Dane in Parkville Great Dane in Peculiar Great Dane in Perryville Great Dane in Pevely Great Dane in Platte City Great Dane in Pleasant Hill Great Dane in Poplar Bluff Great Dane in Raymore Great Dane in Raytown Great Dane in Republic Great Dane in Richmond Great Dane in Richmond Heights Great Dane in Rolla Great Dane in Saint Ann Great Dane in Saint Charles Great Dane in Saint Clair Great Dane in Saint Joseph Great Dane in Saint Louis Great Dane in Saint Peters Great Dane in Salem Great Dane in Savannah Great Dane in Scott City Great Dane in Sedalia Great Dane in Sikeston Great Dane in Smithville Great Dane in Springfield Great Dane in Ste Genevieve Great Dane in Sullivan Great Dane in Town and Country Great Dane in Trenton Great Dane in Troy Great Dane in Union Great Dane in University City Great Dane in Valley Park Great Dane in Vandalia Great Dane in Warrensburg Great Dane in Warrenton Great Dane in Washington Great Dane in Webb City Great Dane in Webster Groves Great Dane in Weldon Spring Great Dane in Wentzville Great Dane in West Plains Great Dane in Wildwood

Great Dane shelters & rescues in Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Missouri. Browse these Great Dane rescues and shelters below.

Here are a few organizations

Rescue

Gods Dogs Rescue of TX for St Louis Transport Stop

St Louis , MO 63146

Pet Types: dogs

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Shelter

Humane Society of Missouri - Maryland Heights

11660 Administration Dr., (Page Ave. and Schuetz Road), Maryland Heights , MO 63146

Pet Types: cats, birds, dogs, rabbits, small animals

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Shelter

City of St. Charles Animal Shelter

2835 W. Randolph St, Saint Charles , MO 63301

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

Forever Friends Great Dane Rescue - Missouri

St. Louis , MO 63017

Pet Types: dogs

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Shelter

No Time to Spare Animal Rescue and Sanctuary

27933 Pendleton Lost Creek Rd, Warrenton , MO 63383

Pet Types: dogs, farm animals, horses

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog ?

We've got all the info you need on adopting and caring for a Great Dane puppy . Check out the links below for everything you ever wanted to know about Great Dane puppies and adults .

Great Dane information

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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