Great Dane Adoption in Missouri: Great Dane Puppies for Sale in Missouri

Adopt a Great Dane near you in Missouri

Below are our newest added Great Danes available for adoption in Missouri. To see more adoptable Great Danes in Missouri, use the search tool below to enter specific criteria!

MORPHEUS

Great Dane

Male, 5 yrs 1 mo

St. Louis, MO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

I am available through HSMO`s Foster-to-Adopt program! I am being treated for heartworm disease, and because the treatment can take a few months, I am able to continue my treatment in your home, rather than stay in the shelter during that time. Once my treatment is over, we can finalize the adoption, making me a permanent member of your family. HSMO will provide all the food, medication, and veterinary care during the foster period, and the staff at HSMO is happy to answer any questions you might have about heartworms. You will need to bring me to the HSMO shelter to see the veterinarian as needed, and to avoid complications from the treatment, I need to be kept as quiet as possible. That means no rough housing or playing hard with people or other pets. I will need to be on leash outside at all times and can only take short, 15-minute walks three to four times a day. However, the good news is that once my treatment is over, I can run and play and be silly again!

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Woody

Great Dane

Male, 2 yrs

Saint James, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Meet Woody! He is hound/Great Dane born 2/19/24. He is a sweet boy. They are used to being around other dogs and playing. He is a complete love bug and just wants to be next to his people. If you're looking for a new best friend, he is your guy. He does well inside and outside. He is heartworm negative. He is neutered, dewormed, vaccinated, current flea/tick prevention and microchipped. If interested, please complete an application found online on our website. Phelpscountyanimalrescue.net Or click link: https://docs.google.com/forms/d/e/1FAIpQLSfVOWjBq3gPoETSQp7kbnbke6Vp4T1rgcWHLnJtM1HmwRIfng/viewform?usp=header Adoption fee $90

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Rocket

Great Dane

Male, 4 yrs 6 mos

Kansas City, MO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

4 1/2 year old Rocket is a big handsome Dane/Mastiff/Pittie mix who has previously lived with other dogs. He loves playing with his stuffy toys and curling up at the foot of the bed. Rocket is vaccinated, neutered and microchipped and ready to go home with you! His ADOPTION FEE IS WAIVED! We want all our dogs to have homes as quickly as possible. In an effort to help dogs with longer stays, those who are deteriorating in the shelter environment, or who are harder to place find homes more quickly, the adoption fee for this dog has been waived.

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Luna B

Great Dane

Female, 4 yrs 1 mo

Neosho, MO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs,

Story

Hi my name is Luna and I am a typical great dane meaning I'm nervous and shy until I get to know you.. Once I'm over that I want to be your best friend and also your couch potato. I pick and chose who I like and don't like as far as other dogs. I do well with puppies best and some male dogs. I would nothing more than to meet you and see if love each other If you would like to do that please let the girls know and they will schedule it for you.

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Bubba 2149

Great Dane/Mixed Breed (Large)

Male, 9 yrs 6 mos

Raytown, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Not good with dogs, Not good with cats, House-trained,

Story

Meet Bubba, The Gentle Giant About Me: I’m a big softie with an even bigger smile. I love people, pets, and being your shadow. I’m friendly, sweet, and happiest when I’m getting head scratches or hanging out in the yard. Best Qualities: • Leash pro 🚶 • Vet’s favorite patient 🩺 • Champion yard runner 🌳 • Expert snuggler 💕 Looking for: A forever family who appreciates a loyal, mature guy who still loves to play but also knows the value of a good nap. Bubba recently went on a dogs day out and this is what was said about him "We took Bubba out for a chill dog day out and he loved all the one on one loving! We didn't plan for any big adventures, just a chill day at our house and he seemed to really love it. He spent a big portion of the day just following Harry around either helping pick up sticks or waiting patiently for more ear scratches! Several dogs walked past our fence line and he seemed interested but didn't bark hardly at all. We had several people over to the house and he warmed up to them right away, resulting in even more ear scratching! Once he sniffed out all the new smells, he found the perfect spot of sunshine in the living room and took a couple naps! On the car rides to and from the shelter, he seemed content just staring out the window at all the new things, but LOVED when we opened the window and he could put his nose out and SMELL all the new things!"

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Alfie

Great Dane/Husky

Male, Senior

Raytown, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, House-trained,

Story

You can fill out an adoption application online on our official website.Please contact Virginia (virginiak@tarasdream.org) for more information about this pet. Please visit our web site at https://tarasdream.org/adopt to fill out an adoption application for this pet and for more info about our adoption process. Tall, dark and handsome, Alfie will sweep you off your feet! He is a playful 7-year-old; if you have a ball, he is always up for a game of fetch. Need a running or walking partner? He will happily join you. He is housetrained, gentle, calm, and gets along with people and other dogs. This loveable guy has had some confusing changes in his life, so it may take him a minute to warm up and feel safe, but, once he does, he loves to be near his human, leaning in for petting. He will need someone to be patient with him as he builds confidence and learns not to be scared of new sounds and places. Alfie does not realize his size, so a home with older children may be best. Come meet Alfie! Approximate Birthdate: July 2017 Adoption Fee: $200 TARA's adoption fee includes: spay/neuter, age appropriate vaccinations, microchip, heartworm test (if age appropriate), heartworm and flea prevention, and deworming. TARA's pets are all eligible for a TWO WEEK TRIAL. Due to the fact that many of our dogs come from the local city shelters, we do not know the background of many of them and therefore cannot always guarantee age or breed. For more information please fill out an application. CONTACT INFO The Animal Rescue Alliance (TARA) Web site: tarasdream.org Adoption Information & Applications: https://tarasdream.org/adopt Upcoming Adoption Events: https://tarasdream.org/events Email: email@tarasdream.org December 21, 2025, 7:43 pm

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Great Dane puppies and dogs in Missouri

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Below are our newest added Great Danes available for adoption in Missouri. To see more adoptable Great Danes in Missouri, use the search tool below to enter specific criteria!

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Great Dane puppies and dogs in Missouri

Jump to:

Adopt a Great Dane near you in Missouri

Below are our newest added Great Danes available for adoption in Missouri. To see more adoptable Great Danes in Missouri, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Missouri cities

Great Dane shelters & rescues in Missouri

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics