Great Dane Adoption in Missouri: Great Dane Puppies for Sale in Missouri

Adopt a Great Dane near you in Missouri

Below are our newest added Great Danes available for adoption in Missouri. To see more adoptable Great Danes in Missouri, use the search tool below to enter specific criteria!

Niko

Great Dane

Male, 6 yrs

St. Joseph, MO

Size

(when grown) -

Details

Story

Learn More

Mack

Great Dane/Mixed Breed (Medium)

Male, 3 mos

Pineville, MO

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Hi there! I'm Mack, a 3-month-old black Great Dane mix, and I'm already neutered and ready for my forever home 🐾 I'm a medium-sized pup with a big heart who loves being around other dogs and kids — I'm still learning the leash, but I'm a quick study. I'm friendly and gentle, and I'd make a wonderful addition to an active family looking for a loyal companion 💙 My adoption fee is $200, and I can't wait to meet you!

Learn More

Bruno

Great Dane/Mixed Breed (Medium)

Male, 3 mos

Pineville, MO

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Hi there! I'm Bruno, a 3-month-old black Great Dane mix with a heart as big as my future paws 🐾. Already neutered and tipping the scales at a solid 33 pounds, I'm a cuddly, gentle boy who loves playing with other dogs and is great with kids too 💕. I'm still learning my manners on the leash, but with a little patience and guidance, I'll be your perfect companion. My adoption fee is $200, and I'm ready to grow into the magnificent gentle giant you've been waiting for — come meet me! 🖤

Learn More

Needs Home Fast

"Big" Duke

Great Dane/Australian Cattle Dog

Male, 6 yrs

Sedalia, MO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

Learn More

Pearl

Great Dane

Female, 5 yrs 1 mo

Rogersville, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Meet Pearl! 🖤🤍 Pearl is a 5-year-old Great Dane in Aurora, Missouri, who is looking for a fresh start. Her owner describes her as a sweet, loving companion who enjoys fetch, knows her commands, is crate trained, and has good recall. She also walks well on a leash when she’s comfortable. After difficult changes in her household, Pearl needs a calm, stable home with someone willing to take things slowly. She has been displaying resource guarding around her owner and home and can growl or snap at unfamiliar people. While she has done well with dogs at daycare and at home, her owner reports that she can also lunge, growl, and attempt to bite other dogs in certain situations, particularly when her owner is present. Her behavior varies by setting, so successful daycare visits don’t guarantee she will be comfortable with every dog. Pearl needs an experienced caregiver prepared to work through these behaviors with professional guidance, thoughtful introductions, and consistent management. Her compatibility with cats is mixed, and any home with other pets would need careful evaluation. Pearl is spayed but needs updated vaccinations and prevention. She has a loving side and a solid foundation of training, and we’re hoping to find someone who can give her the stability, patience, and support she needs for her next chapter.

Learn More

Bramble

Great Dane/Coonhound

Male, Young

Liberty, MO

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Story

Bramble and his siblings were left near a field in rural Missouri. Luckily some good Samaritans spotted them and were able to get 3 of the 4 caught. We worked with volunteer dog trappers to get the last pup caught. These boys are thin and most of them have eye issues. They will be heading to our vet in gladstone for treatment. We are looking desperately for foster homes for each of these pups. They need separated from each other, they need regular feedings, and some tlc as they heal from their surgery. Medical expenses are paid for and we use Animal Clinic of the Woodlands in Gladstone...so foster/adoptive home MUST be able to pick up and drop off their pup at that vet as needed. These boys are TALL and all gangly legged. We aren't sure if they have bloodhound/lab or dane/hound/lab...but these are BIG BOYS. Please reach out to us if you can foster or are interested in adopting one. Bramble was shy, but boy he's come out of his shell quickly. He leans in for petting and is a sweet boy. At Autumn Acres Animal Rescue we believe each individual animal matters. We take in special cases some of which will stay with us as a sanctuary dog.If the animal is listed as a Socially Imperfect Dog this means they have special needs and special requirements for potential adopters.If the animal is listed as a Socially Imperfect RESIDENT this animal is NOT available for adoption and is one of our sanctuary residents. We list them on our sites because they still matter and they still need donations to help with their long term care.Check out our website for more information: http://www.autumnacres.org

Learn More

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Missouri.

Great Dane puppies and dogs in Missouri

Jump to:

Adopt a Great Dane near you in Missouri

Below are our newest added Great Danes available for adoption in Missouri. To see more adoptable Great Danes in Missouri, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Missouri cities

Great Dane shelters & rescues in Missouri

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics

Home

Adopt a Dog

Adopt a Great Dane

Missouri

Great Dane puppies and dogs in Missouri

Jump to:

Adopt a Great Dane near you in Missouri

Below are our newest added Great Danes available for adoption in Missouri. To see more adoptable Great Danes in Missouri, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Missouri cities

Great Dane shelters & rescues in Missouri

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics