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Great Dane puppies and dogs in Buffalo, New York

Looking for a Great Dane puppy or dog in Buffalo, New York? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Buffalo, New York Other pups in Buffalo, New York Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Buffalo, New York Great Dane shelters and rescues in Buffalo, New York Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Buffalo, New York

These Great Danes are available in Buffalo, New York.
Photo of Milo

Milo

Great Dane Mixed Breed (Medium)

Male, 9 mos
Buffalo, NY
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
🐾 Meet Milo — A Resilient Sweetheart Ready for His Fresh Start! 🐾Milo is a 6-month-old Cane Corso mix puppy with a heart full of love and a story of resilience. He and his brother were rescued from a neglect situation, but despite his rough beginning, Milo has proven to be incredibly sweet, gentle, and eager to trust again.This handsome boy is still very much a puppy—playful, curious, and learning about the world around him. He’s already showing how smart and attentive he is, and with continued guidance, he’s going to grow into a loyal, devoted companion. Milo loves attention, enjoys playtime, and is happiest when he’s near his people.As a Cane Corso mix, he will likely grow into a large, strong dog, so he’s looking for a home that understands big breeds and is committed to training, structure, and socialization. In return, Milo will give you unwavering loyalty and love.Milo and his brother have come so far, and now he’s ready for the most important chapter—finding a forever home where he will be safe, loved, and never overlooked again.If you’re ready to give a deserving pup a second chance, Milo may be your perfect match.📍 Located in Texas – can be transported once adopted. Transport fee is $270–$300.📝 Apply here:https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41*Disclaimer: This pet is located in Texas. Once adoption is finalized the pet will be transported to the adopters location for an additional fee (currently $300).* The adoption fee helps to cover some of the cost of vetting the animal prior to adoption (spay/neuter, microchipping, and up to date vaccinations).Please fill out an adoption application to be considered for adoption. https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41

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Or, how about these Great Danes in cities near Buffalo, New York

These Great Danes are available for adoption close to Buffalo, New York.
Photo of Milo

Milo

Great Dane Mixed Breed (Medium)

Male, 9 mos
Buffalo, NY
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
🐾 Meet Milo — A Resilient Sweetheart Ready for His Fresh Start! 🐾Milo is a 6-month-old Cane Corso mix puppy with a heart full of love and a story of resilience. He and his brother were rescued from a neglect situation, but despite his rough beginning, Milo has proven to be incredibly sweet, gentle, and eager to trust again.This handsome boy is still very much a puppy—playful, curious, and learning about the world around him. He’s already showing how smart and attentive he is, and with continued guidance, he’s going to grow into a loyal, devoted companion. Milo loves attention, enjoys playtime, and is happiest when he’s near his people.As a Cane Corso mix, he will likely grow into a large, strong dog, so he’s looking for a home that understands big breeds and is committed to training, structure, and socialization. In return, Milo will give you unwavering loyalty and love.Milo and his brother have come so far, and now he’s ready for the most important chapter—finding a forever home where he will be safe, loved, and never overlooked again.If you’re ready to give a deserving pup a second chance, Milo may be your perfect match.📍 Located in Texas – can be transported once adopted. Transport fee is $270–$300.📝 Apply here:https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41*Disclaimer: This pet is located in Texas. Once adoption is finalized the pet will be transported to the adopters location for an additional fee (currently $300).* The adoption fee helps to cover some of the cost of vetting the animal prior to adoption (spay/neuter, microchipping, and up to date vaccinations).Please fill out an adoption application to be considered for adoption. https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41

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Photo of Stormi

Stormi

Labrador Retriever Great Dane

Female, Puppy
Batavia, NY
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained,
Story
Stormi is a great puppy! She knows sit, shake, easy and she eats on demand. She’s very hyper! She’s amazing with kids, other dogs and people in general. She loves to cuddle and get her belly rubbed. She was born in October of 2026, and from what we were told she’s a mix of Great Dane and Black Lab! We got her from a family that was abusing her, but we’ve brought her back to life & boy is she full of it. I’m not home enough to give her the proper care she needs. She needs a big yard and a loving family :)

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These pups are in Buffalo, New York too!

Below are our newest added Great Danes available for adoption in Buffalo, New York. To see more adoptable Great Danes in Buffalo, New York, use the search tool below to enter specific criteria!
Photo of Rio

Rio

Anatolian Shepherd

Female, 1 yr 6 mos
Buffalo, NY
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Disclaimer: I am located in Texas. I can be transported once adopted. Transport fee is $230.*Disclaimer: This pet is located in Texas. Once adoption is finalized the pet will be transported to the adopters location for an additional fee (currently $300).* The adoption fee helps to cover some of the cost of vetting the animal prior to adoption (spay/neuter, microchipping, and up to date vaccinations).Please fill out an adoption application to be considered for adoption. https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Buffalo, New York.

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Great Dane puppies and dogs in nearby cities

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Related breeds in Buffalo, New York

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Great Dane shelters & rescues in Buffalo, New York

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Buffalo, New York. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

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Sam Coffey Animal Rescue Friends - Buffalo NY Transport

Buffalo, NY 14201

Pet Types: cats, dogs

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Rescue

26.7 miles

Niagara Dog Rescue

Niagara Falls, ON L0S 1J0

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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