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Mastiff puppies and dogs in Mitchell, Indiana

Looking for a Mastiff puppy or dog in Mitchell, Indiana? Adopt a Pet can help you find an adorable Mastiff near you.

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These Mastiffs are available for adoption close to Mitchell, Indiana.
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Lenny

Mastiff Mixed Breed (Medium)

Male, 1 yr 6 mos
Jasper, IN
Size
(when grown) -
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
This handsome guy is just over a year old and we believe he’s a Shepherd/Mastiff mix, weighing around 60 lbs. Lenny has been with us before as a puppy, but due to a change in his previous family’s circumstances, he has found his way back to us and is ready for a fresh start. Lenny can be a little nervous when first meeting new people, but don’t let that fool you—once he warms up, his sweet and gentle personality really shines through. With a little patience and understanding, he quickly becomes a loyal and loving companion who enjoys being close to his people. Lenny has experience living in a home environment and is AMAZING with other dogs, showing he can be a versatile companion in the right setting. Lenny would do best in a home that can give him time to adjust and build his confidence. If you’re willing to go slow and let him come out of his shell, you’ll be rewarded with a truly wonderful best friend.
Photo of TIGER - SOS RESCUE

TIGER - SOS RESCUE

English Mastiff

Male
Morgantown, IN
Size
(when grown) -
Details
Spayed or Neutered,
Story
TIGER! Mastiff mix, 14 months old, brindle Contact:  savingoutstandingsouls@gmail.com  June 1, 2026, 1:05 pm
Photo of Margot

Margot

Mastiff

Female, Adult
Jeffersonville, IN
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered,
Story
Meet Margot! She’s 150lbs of love. Margot is 3 years old. Spayed. She has been with us for 10 months. Margot loves treats and snuggles more than anything else in the world. She’s always happiest snoozing in a comfy bed. Unfortunately Margot has not been able get along with our other dogs so it’s best for her if we find her a home more suitable to her needs. Margot needs a home without other pets and no young children. We’re searching for someone with experience with XL breeds as well.
Photo of Blitz

Blitz

Cane Corso Mastiff

Male, Adult
Underwood, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
We are needing help finding a home for our dog, Blitz. We have had him about 4 months. We are looking for a home for him because he cannot be around cats. We initially kept him separate because our cat was scared of dogs, but whenever he got in the same room as her he ended up killing her. We have another cat and are afraid for his safety as well, as when we tried to introduce them, it became clear that Blitz has a problem with cats. Blitz is a Cane Corso Mastiff, about 18 months old. He weighs roughly 90 pounds. He is an awesome dog. He is always happy to see us. He is an upbeat and happy boy. He is very affectionate. He is great with kids, and the kids loved him. He does get a bit excited, and is also clumsy, stepping on feet or bumping into people. He is also a bit of a chewer if left alone, but will happily chew on a raw hide instead. He has gotten along well with other big dogs after being introduced, but hasn't had experience with little dogs.

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Mastiff shelters & rescues in Mitchell, Indiana

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Mitchell, Indiana. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

34.3 miles

Dubois County Humane Society

426 Wernsing Rd., Jasper, IN 47546

Pet Types: cats, dogs

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Rescue

46.1 miles

LUV A DOG Rescues and Adoptions

Morgantown, IN 46160

Pet Types: cats, dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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