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Mastiff puppies and dogs in Madison, Wisconsin

Looking for a Mastiff puppy or dog in Madison, Wisconsin? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Madison, Wisconsin Other pups in Madison, Wisconsin Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Madison, Wisconsin Mastiff shelters and rescues in Madison, Wisconsin Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Madison, Wisconsin

These Mastiffs are available in Madison, Wisconsin.
Photo of Lilo

Lilo

Mastiff Mixed Breed (Medium)

Female, 8 yrs 5 mos
Madison, WI
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Lilo is a big, sweet-hearted Mastiff who is ready to bring love and loyalty to her forever family! This gentle giant has a calm demeanor and is as friendly as they come. Lilo has been tested with other dogs and did wonderfully, and when walking past cats, she didn’t react at all – so she’s great with both other animals and people. While Lilo may be a little shy at first, her love for human interaction and treats quickly help her open up. She’s a big fan of cuddles and enjoys spending quality time with her people. With some patience, she’ll become your ultimate snuggle buddy and a loyal companion for life. Lilo is looking for a home where she can feel safe, loved, and spoiled with attention. She’s a calm, affectionate dog who would thrive in a household where she’s given the time to adjust and get comfortable. Lilo loves human companionship, and she’ll quickly show you how much she appreciates your kindness – especially if there are some tasty treats involved! If you’re ready to welcome this sweet, giant girl into your heart, Lilo can’t wait to meet you and start her new chapter with you! 🐶💕 All of our dogs are dewormed, spayed/neutered, microchipped, up to date on age appropriate vaccines, and heartworm tested if they are old enough. If you're interested in adopting, please fill out an application on our website at https://www.sftsrescue.org/adoptable-dogs

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Photo of Luna

Luna

Mastiff

Female, 2 yrs
Madison, WI
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
-
Story
****Luna has been with us longer than we would like, so she has been added to the LHC and her adoption fee has been waived****Luna is a beautiful 2-year-old Mastiff with a big heart, a gentle soul, and so much love to give to the right family. Weighing 79.36 pounds, this gorgeous girl is a wonderful example of how much love can come in a large package.Luna is a young adult with a great balance of playful energy and the calm, loyal nature that Mastiffs are known for. She enjoys spending time with her people, being part of the family, and sharing those everyday moments that make a house feel like home. Whether it’s relaxing together, going for walks, or simply being near her favorite humans, Luna is happiest when she feels connected.Because Luna is a big, special girl with her own needs, she is looking for a home that will set her up for success. She would needs a household without small children, where she can enjoy a calm and consistent environment. Luna is also required to be the only dog in the home, giving her the opportunity to receive all the love, attention, and one-on-one companionship she deserves.Luna has so much potential to become an incredible lifelong companion for someone who understands her and appreciates the loyalty and affection she has to offer. In return for patience, kindness, and care, Luna will give her family the devotion and love that make dogs like her so special.If you’re looking for a large, loving companion with a gentle personality and a heart as big as she is, Luna may be the perfect match for you.Medical Information:Luna appears healthy at this time. As with all newly adopted pets, a veterinary examination is recommended following adoption.Weight: 79.36 lbsAdoption Fee: WaivedInterested in meeting Luna? Contact the shelter to learn more about the adoption process and schedule a visit. Luna is ready to find a loving home where she can be cherished as the wonderful dog she is.Please share Luna’s story and help her find the forever family she deserves!

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Or, how about these Mastiffs in cities near Madison, Wisconsin

These Mastiffs are available for adoption close to Madison, Wisconsin.
Photo of Lilo

Lilo

Mastiff Mixed Breed (Medium)

Female, 8 yrs 5 mos
Madison, WI
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Lilo is a big, sweet-hearted Mastiff who is ready to bring love and loyalty to her forever family! This gentle giant has a calm demeanor and is as friendly as they come. Lilo has been tested with other dogs and did wonderfully, and when walking past cats, she didn’t react at all – so she’s great with both other animals and people. While Lilo may be a little shy at first, her love for human interaction and treats quickly help her open up. She’s a big fan of cuddles and enjoys spending quality time with her people. With some patience, she’ll become your ultimate snuggle buddy and a loyal companion for life. Lilo is looking for a home where she can feel safe, loved, and spoiled with attention. She’s a calm, affectionate dog who would thrive in a household where she’s given the time to adjust and get comfortable. Lilo loves human companionship, and she’ll quickly show you how much she appreciates your kindness – especially if there are some tasty treats involved! If you’re ready to welcome this sweet, giant girl into your heart, Lilo can’t wait to meet you and start her new chapter with you! 🐶💕 All of our dogs are dewormed, spayed/neutered, microchipped, up to date on age appropriate vaccines, and heartworm tested if they are old enough. If you're interested in adopting, please fill out an application on our website at https://www.sftsrescue.org/adoptable-dogs

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Photo of Luna

Luna

Mastiff

Female, 2 yrs
Madison, WI
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
-
Story
****Luna has been with us longer than we would like, so she has been added to the LHC and her adoption fee has been waived****Luna is a beautiful 2-year-old Mastiff with a big heart, a gentle soul, and so much love to give to the right family. Weighing 79.36 pounds, this gorgeous girl is a wonderful example of how much love can come in a large package.Luna is a young adult with a great balance of playful energy and the calm, loyal nature that Mastiffs are known for. She enjoys spending time with her people, being part of the family, and sharing those everyday moments that make a house feel like home. Whether it’s relaxing together, going for walks, or simply being near her favorite humans, Luna is happiest when she feels connected.Because Luna is a big, special girl with her own needs, she is looking for a home that will set her up for success. She would needs a household without small children, where she can enjoy a calm and consistent environment. Luna is also required to be the only dog in the home, giving her the opportunity to receive all the love, attention, and one-on-one companionship she deserves.Luna has so much potential to become an incredible lifelong companion for someone who understands her and appreciates the loyalty and affection she has to offer. In return for patience, kindness, and care, Luna will give her family the devotion and love that make dogs like her so special.If you’re looking for a large, loving companion with a gentle personality and a heart as big as she is, Luna may be the perfect match for you.Medical Information:Luna appears healthy at this time. As with all newly adopted pets, a veterinary examination is recommended following adoption.Weight: 79.36 lbsAdoption Fee: WaivedInterested in meeting Luna? Contact the shelter to learn more about the adoption process and schedule a visit. Luna is ready to find a loving home where she can be cherished as the wonderful dog she is.Please share Luna’s story and help her find the forever family she deserves!

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Photo of King - Adoption Fee Paid!

King - Adoption Fee Paid!

Mastiff

Male, Adult
Jefferson, WI
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered, Shots are up-to-date,
Story
6 years old (estimated) Neutered Male  106 lbs. Has done well with other dogs  Looking for a home without cats  No known experience with kids  Meet King, an extra-large teddy bear with an even bigger heart! This handsome boy loves attention and is happiest when he's spending time with his people, soaking up pets and showing off his signature big smile. King enjoys exploring the outdoors, especially when he can take his time sniffing around and checking out all the interesting scents along the way. He also likes going for walks, although King prefers to keep them on his own terms. When he's decided he's had enough, he'll happily sit down and anchor himself right where he is, letting everyone know the adventure is over for the day. With his lovable personality, laid-back attitude, and charming grin, King is sure to bring plenty of smiles and laughter to the lucky family who welcomes him home. King's adoption fee had been paid by a generous member of our community! The online adoption listing websites require that we choose a predominant breed or breed mix for our dogs. Visual breed identification in dogs is unreliable so for most of the dogs we are only guessing at predominant breed or breed mix. We encourage you to select your new companion by considering each dog's individual personality and pet qualities instead of relying on a breed label that is only a guess.June 28, 2026, 1:00 am

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Mastiff puppies and dogs in nearby cities

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Mastiff shelters & rescues in Madison, Wisconsin

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Madison, Wisconsin. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

2.3 miles

Shelter from the Storm Animal Rescue

1602 Blossom Ln, Madison, WI 53716

Pet Types: cats, birds, dogs, rabbits, small animals

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Shelter

5.8 miles

Dane County Humane Society

5132 Voges Rd, Madison, WI 53718

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

26.4 miles

Humane Society of Jefferson County

W6127 Kiesling Rd, Jefferson, WI 53549

Pet Types: cats, birds, dogs, farm animals, rabbits, reptiles, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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