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Neapolitan Mastiff puppies and dogs in Santa Clarita, California

Looking for a Neapolitan Mastiff puppy or dog in Santa Clarita, California? Adopt a Pet can help you find an adorable Neapolitan Mastiff near you.

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Adopt a Neapolitan Mastiff near you in Santa Clarita, California

We don't see any Neapolitan Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Neapolitan Mastiffs in cities near Santa Clarita, California

These Neapolitan Mastiffs are available for adoption close to Santa Clarita, California.
We'll also keep you updated on DALTON's adoption status with email updates.
Needs Home Fast
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DALTON

Neapolitan Mastiff

Male, 3 yrs 3 mos
Chatsworth, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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We'll also keep you updated on TEDDY's adoption status with email updates.
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TEDDY

Neapolitan Mastiff

Male, 1 yr 11 mos
Lancaster, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
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We'll also keep you updated on Zen's adoption status with email updates.
Photo of Zen

Zen

Neapolitan Mastiff Mastiff

Male, 5 yrs 3 mos
Beverly Hills, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 4-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!

These pups are in Santa Clarita, California too!

Below are our newest added Neapolitan Mastiffs available for adoption in Santa Clarita, California. To see more adoptable Neapolitan Mastiffs in Santa Clarita, California, use the search tool below to enter specific criteria!
We'll also keep you updated on Jayse's adoption status with email updates.
Photo of Jayse

Jayse

Great Dane American Pit Bull Terrier

Male, 8 mos
Agua Dulce, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Meet Jayse, He’s an 8 month old Great Dane/Pit mix. He’s going to be around 65 lbs Super sweet - was found out in the desert by a film crew. We got him neutered and fully vetted and he’s ready for a forever family. Great with kids. Getting used to trusting other dogs. Crate and leash trained. Comes with 5 training classes. $100-Adoption fee. If interested please come out to our ranch ( 34128 Agua Dulce Canyon Road in Santa Clarita) any day between 8-6.
We'll also keep you updated on Schnookie's adoption status with email updates.
Photo of Schnookie

Schnookie

St. Bernard Border Collie

Female, 2 yrs 9 mos
Agua Dulce, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Schnookie, she is a 2 1/2 year old and a Saint Bernard Collie mix. Schnookie, is a chunky sweetheart, good with other dogs, cats, and kids. A little shy at first with men, needs to be crated at night and not left alone in a yard by herself but such an easy squishy loving girl. . $100 adoption fee. She is spayed, vaccinated, and ready for her home. 5 training classes are also included If interested, please come by our ranch ( 34128 Agua Dulce Canyon Road in Santa Clarita) any day 8-6
We'll also keep you updated on Remy's adoption status with email updates.
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Photo of Remy

Remy

Great Dane German Shepherd Dog

Male, Young
Santa Clarita, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Remy was acquired from the local animal shelter, at the time his owner (I'm the cousin of his owner!) was underage and her family agreed together to adopt another dog as their first family dog was passing from old age. Remy has a lot of experience with other dogs due to this, and turned 3 years old on November 19, 2025. Unfortunately as time went on my cousin was given all responsibility for Remy with no help from the family, and it's not a safe household for either of them. My cousin needs to move out but can't leave Remy behind, he deserves a loving home that truly wants to commit to him long term. He could use a large yard due to his size, or frequent outings. He has a brief history of being scared of adult men to the point he will bark and protect his owner (my cousin.) However, he is a very sweet boy. He loves his family despite everyone but my cousin neglecting him. It breaks my cousin to have to rehome him, but it's best for both of them. Please give him a chance!

Search for a Neapolitan Mastiff puppy or dog

Use the search tool below to browse adoptable Neapolitan Mastiff puppies and adults Neapolitan Mastiff in Santa Clarita, California.

Neapolitan Mastiff puppies and dogs in nearby cities

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Neapolitan Mastiff shelters & rescues in Santa Clarita, California

There are animal shelters and rescues that focus specifically on finding great homes for Neapolitan Mastiff puppies in Santa Clarita, California. Browse these Neapolitan Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

18.2 miles

West Valley Animal Care Center - Los Angeles Animal Services

20655 Plummer Street, Chatsworth, CA 91311

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

20.4 miles

Los Angeles County: Lancaster

5210 W. Ave. I, Lancaster, CA 93536

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

29.7 miles

Ace of Hearts Dog Rescue - CA

PO Box 2357, Beverly Hills, CA 90213

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Neapolitan Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Neapolitan Mastiff puppy. Check out the links below for everything you ever wanted to know about Neapolitan Mastiff puppies and adults.

Neapolitan Mastiff basics

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Where do Neapolitan Mastiffs come from? How many types of Neapolitan Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Neapolitan Mastiff.

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