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Great Dane puppies and dogs in Santa Clarita, California

Looking for a Great Dane puppy or dog in Santa Clarita, California? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Santa Clarita, California Other pups in Santa Clarita, California Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Santa Clarita, California Great Dane shelters and rescues in Santa Clarita, California Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Santa Clarita, California

These Great Danes are available in Santa Clarita, California.
We'll also keep you updated on Lux's adoption status with email updates.
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Lux

Great Dane English Mastiff

Male, 2 yrs 2 mos
Santa Clarita, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
The #Busan Dog Slaughterhouse was discovered not far from the #Busan Dog Department Store. The site, where many animals were slaughtered, bore horrifying traces on the various machines and tools. In a place where death is a daily reality, WEACT rescued #weact_lux .

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Or, how about these Great Danes in cities near Santa Clarita, California

These Great Danes are available for adoption close to Santa Clarita, California.
We'll also keep you updated on Lux's adoption status with email updates.
Photo of Lux

Lux

Great Dane English Mastiff

Male, 2 yrs 2 mos
Santa Clarita, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
The #Busan Dog Slaughterhouse was discovered not far from the #Busan Dog Department Store. The site, where many animals were slaughtered, bore horrifying traces on the various machines and tools. In a place where death is a daily reality, WEACT rescued #weact_lux .

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We'll also keep you updated on Zena A2019230's adoption status with email updates.
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Zena A2019230

Great Dane

Female, 6 yrs 9 mos
Mission Hills, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
- Loyal and loving to her trusted people. - Low energy with occasional zoomies and play time. - Prefers to be your one and only pup in the home. - Would love a calm and quiet home to see her blossom

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We'll also keep you updated on Sampson's adoption status with email updates.
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Sampson

Great Dane

Male, 4 yrs 3 mos
Shadow Hills, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
What a Gentle Gian! Pure, AKS, boy. Need a lot of activities. He is great with most of dogs if they do not go into his face. He loves people and completely trained. He is very healthy and idea that big dog do not live long is not reliable anymore. He has another at least 10 years. She is healthy boy, beautiful, smart and imprinted on his owner. He is great with any humans and most of dog. Right now he is staying in the foster home with Coco - bishon/poodle mix boy.

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We'll also keep you updated on Luna's adoption status with email updates.
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Luna

Great Dane

Female, Young
Palmdale, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
Meet Our Sweet Great Dane I am looking to rehome my all-black Great Dane (with a small white patch on her chest). She is a very sweet, affectionate girl who loves attention, belly rubs, and being around people. energetic, playful, and enjoys spending time outside. She would do great with someone who can give her space to run, plenty of love, and lots of playtime. a wonderful dog & needs the right home where she can thrive.

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We'll also keep you updated on Barney's adoption status with email updates.
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Barney

Great Dane Mixed Breed (Medium)

Male, Young
Valley Village, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs,
Story
Meet Barney! Barney is a sweetheart that was sadly abandoned by his owner in a local dog park. Due to that, Barney is definitely a shy guy and takes a minute to warm up to other humans, but once he does, there is no escape from the love-fest you are about to receive! Barney LOVES any and all dogs. Other dogs seem to comfort him and give him a sense of familiarity and happiness. Barney is a true gentleman and love bug, so if you're ready to shower this pup with kisses, then Barney is the dog for you. Adopt Barney! Please visit our website bigloveanimalrescue.org to learn more about this amazing pet and to see other available dogs.

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We'll also keep you updated on GRACIE's adoption status with email updates.
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GRACIE

Great Dane

Female, Adult
Woodland Hills, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Meet Gracie – A Survivor with a Heart of Gold Gracie’s story is one of resilience and hope. This beautiful Great Dane mix was rescued just in time from the euthanasia list at the Riverside County Animal Shelter. Now safe and surrounded by care, Gracie is ready to start her next chapter—in a loving home where she can finally thrive. Gracie at a Glance: Age: Approx. 4–5 years old Weight: ~55 lbs Spayed, vaccinated, and microchipped Friendly and affectionate with people Dog-friendly Gracie is more than just a survivor—she’s a gentle soul who is eager to connect and form a deep bond with someone special. Whether it's cuddling on the couch or joining you for a quiet walk, she’ll be your loyal and loving companion through it all. Ready to Adopt or Foster-to-Adopt? Gracie has already fought hard for her second chance—now she just needs someone to say “yes” to forever. If you're ready to open your heart and home to this incredible girl, please reach out to the rescue to learn more or schedule a meet-and-greet. Let Gracie show you what true gratitude and unconditional love look like.    August 25, 2025, 1:13 am

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These pups are in Santa Clarita, California too!

Below are our newest added Great Danes available for adoption in Santa Clarita, California. To see more adoptable Great Danes in Santa Clarita, California, use the search tool below to enter specific criteria!
We'll also keep you updated on RAYA's adoption status with email updates.
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RAYA

Anatolian Shepherd Great Pyrenees

Female, 1 yr
Santa Clarita, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
This sweet, beautiful and funny girl is still a pup! She is FANTASTIC. So easy going and fun. She is very loyal to humans and wants to belong. She listens. She goes with the flow and is ready to go on adventures or just chill with you on the couch if that is what you want to do. She loves treats and yummy food. She gets along with other dogs and loves to play with them. She walks easy on leash. RAYA did have puppies at 9 months old. She was surrendered to us with her puppies by a senior citizen who had her as a puppy and could not longer care for her. She was the sweetest most loving dog mom to them. They all got adopted at 10 weeks old. We want RAYA to be seen and loved and appreciated for the wonderful dog that she is. PLEASE ask us to meet her or for an application by texting the rescue at (747) 313-2971. RAYA is in the Los Angeles area. A home visit and interview are required prior to adoption.

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Santa Clarita, California.

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Great Dane puppies and dogs in nearby cities

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Related breeds in Santa Clarita, California

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Great Dane shelters & rescues in Santa Clarita, California

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Santa Clarita, California. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

7.1 miles

WEACT

Santa Clarita, CA 91354

Pet Types: dogs

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Shelter

13.9 miles

Paws for Life K9 Rescue

15321 Brand Blvd., Mission Hills, CA 91345

Pet Types: dogs

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Rescue

16.5 miles

SavingLittle Strays Rescue

Shadow Hills, CA 91040

Pet Types: dogs, farm animals, horses

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Rescue

22.1 miles

Big Love Animal Rescue

Valley Village, CA 91607

Pet Types: dogs

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Rescue

23.5 miles

Melita's Dream Animal Rescue

21200 Oxnard St, #6492, Woodland Hills, CA 91365

Pet Types: dogs

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Shelter

28.5 miles

Pasadena Humane

361 S. Raymond Ave, Pasadena, CA 91105

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

28.6 miles

Joyful Pets Rescue - Los Angeles

Los Angeles, CA 90048

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

29.7 miles

Ace of Hearts Dog Rescue - CA

PO Box 2357, Beverly Hills, CA 90213

Pet Types: dogs

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Rescue

32.1 miles

Tails of the City Animal Rescue

Los Angeles, CA 90018

Pet Types: dogs

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Rescue

36.6 miles

The Lovejoy Foundation, Inc.

1121 W.Hillcrest Blvd. Inglewood,CA 90301, 11-5pm Sat, and 11-5pm Sun, See facebook for more info, Inglewood, CA 90301

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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