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Neapolitan Mastiff puppies and dogs in Denver, Colorado

Looking for a Neapolitan Mastiff puppy or dog in Denver, Colorado? Adopt a Pet can help you find an adorable Neapolitan Mastiff near you.

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Adopt a Neapolitan Mastiff near you in Denver, Colorado

These Neapolitan Mastiffs are available in Denver, Colorado.
We'll also keep you updated on Zen's adoption status with email updates.
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Zen

Neapolitan Mastiff Mastiff

Male, 7 yrs 2 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 6-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Neapolitan Mastiff Neapolitan Mastiff

Male, 8 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Meet Moose! ✔️good with kids ✔️ good with dogs ✔️ neutered The most beautiful, stunning, perfectly well behaved gentle giant !! Moose is in doggy daycare and has proven himself a perfect gentleman. He was actually purchased from a breeder as a puppy, and the family has a baby on the way, and do not have the time to commit to moose, which is why they trusted us to find him a wonderful and suitable forever home. He's neutered, UTD on vaccines , microchipped , walks beautifully on leash and eats 8 cups of food a day! https://new.shelterluv.com/matchme/adopt/BCAR/Dog Transport is an additional $185

Or, how about these Neapolitan Mastiffs in cities near Denver, Colorado

These Neapolitan Mastiffs are available for adoption close to Denver, Colorado.
We'll also keep you updated on Zen's adoption status with email updates.
Photo of Zen

Zen

Neapolitan Mastiff Mastiff

Male, 7 yrs 2 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 6-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Neapolitan Mastiff Neapolitan Mastiff

Male, 8 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Meet Moose! ✔️good with kids ✔️ good with dogs ✔️ neutered The most beautiful, stunning, perfectly well behaved gentle giant !! Moose is in doggy daycare and has proven himself a perfect gentleman. He was actually purchased from a breeder as a puppy, and the family has a baby on the way, and do not have the time to commit to moose, which is why they trusted us to find him a wonderful and suitable forever home. He's neutered, UTD on vaccines , microchipped , walks beautifully on leash and eats 8 cups of food a day! https://new.shelterluv.com/matchme/adopt/BCAR/Dog Transport is an additional $185
We'll also keep you updated on Gina's adoption status with email updates.
Photo of Gina

Gina

Neapolitan Mastiff Cane Corso

Female, 7 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs,
Story
She is 80% neopolitan mastiff and 20% Cane Corso. She is 7 Months old and 90 pounds. She is a very wiggly and happy puppy with so much extra skin and the cutest butt wrinkles you have ever seen. She was born from a pregnant neopolitan mother we rescued from the shelter and when we got the DNA back and found out the puppies were 100% mastiff that was pretty exciting! She is great with other dogs, she likes to play a lot and she has been around small dogs but she may play a little rough for tiny ones. She has been around cats but occasionally tries to chase. She is extremely affectionate and cuddly. She is crate trained and pretty well potty trained. To excellent home only, please tell me about yourself.

These pups are in Denver, Colorado too!

Below are our newest added Neapolitan Mastiffs available for adoption in Denver, Colorado. To see more adoptable Neapolitan Mastiffs in Denver, Colorado, use the search tool below to enter specific criteria!
We'll also keep you updated on Chevy's adoption status with email updates.
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Chevy

Great Dane

Female, Adult
Lakewood, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
For more information about this Dane, please visit our website at https://rmgreatdane.org. Adoption Applications link can be found on the home page. Chevy has officially settled into her foster home, and now this one-of-a-kind Great Dane is ready to find her forever family! She’s five years old, merle-colored, and packed with more personality than her giant paws can hold. Let’s get one thing straight—Chevy is a total sweetheart . She’s affectionate, playful, and talkative (with the cutest little grumbles). If you’re looking for a Velcro dog who leans in hard for love, insists on couch snuggles, and lives for grass zoomies, this girl might just be your soul-dog. But—real talk—Chevy is also a work in progress. Personality Snapshot Chevy is: A snuggly couch potato A toy-destroying queen A leaner and lap dog (yes, all 100+ pounds of her) A full-on clown when she’s in a playful mood &#239&#184&#143 Talkative, mouthy, and all about the kisses Obsessed with grass rolls (seriously, it’s her zen zone) Extremely fearful of strangers, new sounds, sudden movements… and apparently grills. Once she trusts you, though? She’s all in. Expect face nibbles, dramatic flops, and lots of paw swats for attention. She’s got more enthusiasm for life than most people at a theme park. Training & Habits Chevy knows several commands including: &#226&#156&#148&#239&#184&#143 Sit &#226&#156&#148&#239&#184&#143 Down &#226&#156&#148&#239&#184&#143 Stay &#226&#156&#148&#239&#184&#143 Come &#226&#156&#148&#239&#184&#143 Off Plus, she responds to hand signals like a champ. She’s crate trained, house-trained (mostly—occasional accidents happen), and totally food motivated. She waits patiently at mealtime, even if you’re cruel and make her sit for 10 whole minutes. (You monster. LOL) Chevy walks okay on a nose-loop leash but does pull if she sees something “suspicious” (read: a stroller, a trash bin, or the aforementioned grill). She’s currently working on desensitization and doing her best! And yes—she counter surfs and has been known to shred a blanket or two when anxious. But hey, no one’s perfect. Fears & Challenges Chevy is working through her fears and needs someone committed to training and confidence building. She reacts to: ‍&#226&#153&#130&#239&#184&#143 Strangers (especially men) Kids (less scary than men, but still suspicious) Dogs (aggressive barking from afar) Loud or sudden noises Fireworks, vacuums, and other chaos She barks, growls, and can act out, out of fear. Her tail is often tucked, and her body language screams “please don’t hurt me” more than “go away.” With slow intros and positive reinforcement, she’s made steps forward—but she’ll need a family who truly gets it. What Chevy Needs Chevy isn’t a plug-and-play pup. She’s looking for: A calm, structured home Patient, experienced dog people Dog Savvy Adults or teens only (no young kids) A fenced yard for zoomies and grass therapy A routine—seriously, she thrives on schedule People who will laugh when she sits like a cat She’s not currently dog or cat-tested in close quarters, but based on her reactivity, she’ll do best as the only pet in the home. &#226&#157&#164&#239&#184&#143 Why She’s Worth It Chevy might never be the dog you take to a busy café or the farmers market. But she will be the dog who makes you laugh every single day. Who cuddles hard. Who teaches you patience, trust, and the magic of tiny victories. She is goofy. She is loving. She is flawed. And she is so ready for a home that sees her heart and wants to help it heal. More about Chevy: House-trained: Yes – still has occasional accidents.  Crate trained: Yes Needs a calm home – dog savvy adults and teens only No dogs – has shown reactivity from a distance No cats – high prey drive Will counter surf and steal food – needs supervision  Basic Obedience Training complete – knows sit, stay, come, down, off Fearful and anxious around new people – needs slow introductions Pulls when excited on leash – needs additional training May 12, 2025, 9:41 am
We'll also keep you updated on Loki's adoption status with email updates.
Photo of Loki

Loki

Great Dane

Male, 4 yrs 1 mo
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
 Meet Loki At 135 pounds of pure love and personality, Loki is a 4-year-old Great Dane looking for his forever home! He’s a big sweetheart who’s powered by snuggles and thrives when he can be close to his people—so he’s hoping to find a human who works from home and doesn’t mind a constant cuddle buddy. Despite his size, Loki still gets the zoomies and loves to romp around when the mood strikes! He’s crate and potty trained, though he’ll let you know (loudly!) if he’s put in a crate without a comfy bed—this guy loves his cozy spots. Loki can be a little cautious when meeting new people and may growl at first, but once he warms up, he’s full of affection—offering endless kisses, hugs, and heart-melting loyalty.He would do well in a home with or without another dog. Because of his size and sensitive nature, a home with Great Dane experience is highly recommended. Loki also has a high prey drive, so consistent leash training is a must to help him stay focused and safe on walks. If you’re looking for a big-hearted companion who will fill your home with love, laughter, and the occasional zoomie, Loki might just be your perfect match. ##2565971##
We'll also keep you updated on Huckleberry's adoption status with email updates.
Photo of Huckleberry

Huckleberry

Great Dane

Male, 7 mos
Denver, CO
Size
(when grown) -
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Meet Huckleberry — the wonderfully clumsy, extra-large goofball who’s about to steal your heart! This sweet boy is still figuring out how to operate all those legs, which makes him equal parts majestic and totally hilarious. But don’t let the goofy exterior fool you — Huckleberry is smart, eager to please, and already sits like an absolute pro. He’s working on “stay,” “wait,” and “lay down,” and you can almost see the gears turning as he looks to his foster for direction. He loves learning. Huckleberry is also a champion walker. He’d happily stroll all day long on his loose leash, politely taking corrections and doing his best to stay on one side — we’re still perfecting that part.  He’s currently underweight and rocks a cozy sweater on outdoor adventures while he works toward a healthier size (and honestly, he looks adorable). He’s a social butterfly, too! Huckleberry plays beautifully with his canine foster sister, has met other dogs like a gentleman, and is cautiously curious about the resident cat (slow introductions in progress!). But the real magic? Huckleberry’s heart. He is a sensitive, gentle giant who LOVES his person with his whole being. He’s a Velcro dog in the best way — always close by, always wanting connection, always ready for a snuggle and leaning in for affection. If you’re looking for a loyal companion, a playful pal, and a big ol’ cuddle bug wrapped into one irresistibly long-legged package… Huckleberry is your guy. Come meet this “little big man” — you won’t be able to walk away without falling in love. ##2601986##

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Neapolitan Mastiff shelters & rescues in Denver, Colorado

There are animal shelters and rescues that focus specifically on finding great homes for Neapolitan Mastiff puppies in Denver, Colorado. Browse these Neapolitan Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

6 miles

Ace of Hearts Dog Rescue - CO Transport Stop

711 Walnut St, Boulder, CO 80203

Pet Types: dogs

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Rescue

25.1 miles

Redline Rescue

Boulder, CO 80301

Pet Types: cats, dogs

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Want to learn more about adopting a Neapolitan Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Neapolitan Mastiff puppy. Check out the links below for everything you ever wanted to know about Neapolitan Mastiff puppies and adults.

Neapolitan Mastiff basics

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Where do Neapolitan Mastiffs come from? How many types of Neapolitan Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Neapolitan Mastiff.

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