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Neapolitan Mastiff puppies and dogs in Denver, Colorado

Looking for a Neapolitan Mastiff puppy or dog in Denver, Colorado? Adopt a Pet can help you find an adorable Neapolitan Mastiff near you.

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Adopt a Neapolitan Mastiff near you in Denver, Colorado

These Neapolitan Mastiffs are available in Denver, Colorado.
We'll also keep you updated on Zen's adoption status with email updates.
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Zen

Neapolitan Mastiff Mastiff

Male, 7 yrs 4 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 6-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Neapolitan Mastiff Neapolitan Mastiff

Male, 9 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Meet Moose! ✔️good with kids ✔️ good with dogs ✔️ neutered The most beautiful, stunning, perfectly well behaved gentle giant !! Moose is in doggy daycare and has proven himself a perfect gentleman. He was actually purchased from a breeder as a puppy, and the family has a baby on the way, and do not have the time to commit to moose, which is why they trusted us to find him a wonderful and suitable forever home. He's neutered, UTD on vaccines , microchipped , walks beautifully on leash and eats 8 cups of food a day! https://new.shelterluv.com/matchme/adopt/BCAR/Dog Transport is an additional $185

Or, how about these Neapolitan Mastiffs in cities near Denver, Colorado

These Neapolitan Mastiffs are available for adoption close to Denver, Colorado.
We'll also keep you updated on Zen's adoption status with email updates.
Photo of Zen

Zen

Neapolitan Mastiff Mastiff

Male, 7 yrs 4 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 6-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Neapolitan Mastiff Neapolitan Mastiff

Male, 9 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Meet Moose! ✔️good with kids ✔️ good with dogs ✔️ neutered The most beautiful, stunning, perfectly well behaved gentle giant !! Moose is in doggy daycare and has proven himself a perfect gentleman. He was actually purchased from a breeder as a puppy, and the family has a baby on the way, and do not have the time to commit to moose, which is why they trusted us to find him a wonderful and suitable forever home. He's neutered, UTD on vaccines , microchipped , walks beautifully on leash and eats 8 cups of food a day! https://new.shelterluv.com/matchme/adopt/BCAR/Dog Transport is an additional $185

These pups are in Denver, Colorado too!

Below are our newest added Neapolitan Mastiffs available for adoption in Denver, Colorado. To see more adoptable Neapolitan Mastiffs in Denver, Colorado, use the search tool below to enter specific criteria!
We'll also keep you updated on Ajax's adoption status with email updates.
Photo of Ajax

Ajax

Great Dane

Male, 4 yrs 4 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
Ajax is a handsome four year old blue merle Great Dane with a friendly, curious, and eager to please disposition. He was transferred to rescue after finding himself in a midwestern municipal shelter. Ajax arrived underweight, having been neglected by his prior owner, but is doing well in foster care. He is a bit of a "velcro dog," as Danes are apt to be, and would love the devotion of his very own family. Ajax enjoys going anywhere where there is attention to be given to him, and appears to do well with humans and dogs of all sizes, though he can get very excited during play, which will not work for every kind of friend. He is neutered, fully vaccinated, microchipped, heartworm negative, wormed, on heartworm prevention; we do not believe he has had a gastropexy. Ajax's adoption fee is $350.
We'll also keep you updated on Chevy's adoption status with email updates.
Photo of Chevy

Chevy

Great Dane

Female, Adult
Lakewood, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
For more information about this Dane, please visit our website at https://rmgreatdane.org. Adoption Applications link can be found on the home page. Updated 11-17-2025 Meet Chevy, a stunning merle Great Dane with a soft heart, a goofy spirit, and a journey that’s taken a lot of courage. At 5 years old, Chevy has made incredible progress in professional training, and she’s ready to find a patient, experienced family who can continue helping her grow. Personality Chevy is a shy girl at first, especially with new people and new experiences. She startles easily and can be fearful, but once she feels safe, her true personality shines. With her trusted humans, she transforms into a big, affectionate snugglebug who loves belly rubs, couch cuddles, and lounging on her back like a silly, happy seal. She’s a Velcro dog, a world-class leaner, and will happily wiggle right into your lap if you let her. She’s playful too—zoomies, rolling in the grass, and ripping squeakers out of toys are among her favorite hobbies. Training & Progress Chevy is house trained, crate trained, and knows all her basics: sit, down, come, stay, and off. She’s very treat-motivated and responds beautifully in controlled training environments. Her biggest challenge is her fear of people and dogs. Outdoors, she may bark, snap, or lunge when scared—and strangers, sudden noises, or unfamiliar dogs can be overwhelming. But with a professional trainer, she has been calm, neutral, and noticeably improving. Her foster family reports consistent progress, especially with careful, structured introductions. Chevy will absolutely thrive with a family committed to continuing her positive-reinforcement training, managing her environment, and helping her confidence grow at her pace. Ideal Home Chevy’s perfect family will offer: A quiet, predictable home with minimal surprises A fenced yard or outdoor space for zoomies and grass-rolling No other dogs or pets   Adults only, or possibly older dog-savvy teens Experience with fearful or reactive dogs (or willingness to learn) Compassion, structure, patience, and consistency She bonds deeply with her people and can be anxious when separated, but she’s getting much better about calmly settling in her kennel when home alone. Other Good Stuff LOVES car rides and will hop right into the back seat without hesitation Non-destructive in the home (other than defeating her kennel bedding!) Sleeps in the bed and loves snuggling Very gentle with food—she’ll wait for permission before eating Healthy overall, with one tooth (a fang) that will need removal &#226&#157&#164&#239&#184&#143 Why You’ll Love Her Chevy is an incredibly loving, sensitive girl who just needs someone that believes in her. She may take weeks to fully settle in, but once she does, she gives her whole heart. Her goofy zoomies, her wiggly cuddle demands, her brave steps forward in training—these moments will make you fall in love with her over and over. If you’re looking for a devoted companion and are ready to help a sweet, fearful Dane blossom into her best self, Chevy may be the dog you’ve been waiting for. More about Chevy: Great Dane Experience Required Housetrained:Yes  Crate trained: Yes Needs a calm home – dog savvy adults and teens only No dogs – has shown reactivity from a distance No cats – high prey drive Professional training in process Fearful and anxious around new people – needs slow introductions Are you interested in adopting or fostering-to-adopt Chevy, reach out to Candice at placements@rmgreatdane.org.December 30, 2025, 1:01 pm
We'll also keep you updated on Loki's adoption status with email updates.
Photo of Loki

Loki

Great Dane

Male, 4 yrs 2 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hello world! My name is Loki, and I’m so glad you clicked on my profile. I’m a 130-pound Great Dane with an even bigger heart, and I can’t wait to find my forever home!A few things you should know about me: I can be a little nervous when meeting new people. My first meet-and-greet may involve some cautious sniffs while I get comfortable. I’m currently working with my foster parents and a trainer to build my confidence and learn better ways to communicate when I’m unsure. Like many sensitive dogs, I’ve occasionally used quick warning snaps when I feel overwhelmed or confused. Because of this, I need a home that understands canine body language, respects my boundaries, and is committed to continuing my training so I feel safe and supported. I have a high prey drive when wearing a flat collar (those squirrels really test me!), but when I’m on a prong collar, I’m a total gentleman and can calmly pass squirrels and bunnies.Once I know you, I am the sweetest, cuddliest, and most loyal companion you could ask for. I love hugs, kisses, and being close to my people—expect lots of affection! Ultimately, I’m looking for a patient, dog-savvy adopter—ideally with large-breed experience—who understands what they’re signing up for and is excited to work with me so I can be the best pup I can be. In return, I’ll give you unwavering loyalty, love, and a whole lot of Dane-sized snuggles.  ##2565971##

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Neapolitan Mastiff shelters & rescues in Denver, Colorado

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Here are a few organizations closest to you:

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6 miles

Ace of Hearts Dog Rescue - CO Transport Stop

711 Walnut St, Boulder, CO 80203

Pet Types: dogs

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Want to learn more about adopting a Neapolitan Mastiff puppy or dog?

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Neapolitan Mastiff basics

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Where do Neapolitan Mastiffs come from? How many types of Neapolitan Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Neapolitan Mastiff.

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