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Great Dane puppies and dogs in Denver, Colorado

Looking for a Great Dane puppy or dog in Denver, Colorado? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Denver, Colorado

These Great Danes are available in Denver, Colorado.
Photo of Chevy

Chevy

Great Dane

Female, Adult
Lakewood, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
For more information about this Dane, please visit our website at https://rmgreatdane.org. Adoption Applications link can be found on the home page. Meet Chevy   Status: Available Sex: Spayed Female – Gastropexied Color: Merle    Ears: Natural Age: 6 yrs  Weight: 108 lbs Great Dane Experience Required Adoption Fee – has been paid by a generous sponsor   Chevy is a beautiful 6-year-old merle Great Dane looking for a special home that understands her needs and is ready to help her continue building confidence. At her core, Chevy is an incredibly loyal Dane who forms deep bonds with her people. Once she trusts you, she'll happily follow you from room to room, curl up nearby while you relax, and remind you why Great Danes are known for their devotion. She loves playing fetch with her Kong stick, zooming around the yard, and soaking up time with her favorite humans. Chevy is house-trained, crate-trained, knows basic commands including sit, down, come, stay, and off, and responds well to hand signals. She enjoys learning, especially when rewarded with her favorite all-natural treats. While Chevy has many wonderful qualities, she is looking for a very specific home where she can thrive. Chevy can be reactive to people and animals she sees through windows, on walks, or while riding in the car. She will bark and lunge when triggered and will need continued training, patience, and consistent leadership to help her work through these behaviors. Because of her reactivity, Chevy must be the only pet in the home. She is not a candidate for homes with other dogs, cats, or small animals. She also requires an adult-only home with no children. Chevy's ideal adopter will have previous giant breed experience, understand canine body language, and be committed to continuing her training and confidence-building. She would do best in a calm, predictable environment with a securely fenced yard where she can safely run and play. In return, Chevy offers unwavering loyalty, affection, and companionship. She settles in quickly with her people, enjoys spending time with her family, and loves nothing more than being close to the person she trusts. If you're an experienced giant breed owner looking for a devoted companion and are willing to provide the structure and training Chevy needs, she may be the perfect addition to your family. More about Chevy: Great Dane Experience Required Housetrained:Yes Crate trained: Yes Needs a calm home - dog savvy adults and teens only No dogs No cats Reactive to new people and dogs Professional training in process and will need to be continued Fearful and anxious around new people - needs slow introductions   July 25, 2026, 12:12 am

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Photo of Milo

Milo

Great Dane Mixed Breed (Medium)

Male, 8 mos
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
🐾 Meet Milo — A Resilient Sweetheart Ready for His Fresh Start! 🐾Milo is a 6-month-old Cane Corso mix puppy with a heart full of love and a story of resilience. He and his brother were rescued from a neglect situation, but despite his rough beginning, Milo has proven to be incredibly sweet, gentle, and eager to trust again.This handsome boy is still very much a puppy—playful, curious, and learning about the world around him. He’s already showing how smart and attentive he is, and with continued guidance, he’s going to grow into a loyal, devoted companion. Milo loves attention, enjoys playtime, and is happiest when he’s near his people.As a Cane Corso mix, he will likely grow into a large, strong dog, so he’s looking for a home that understands big breeds and is committed to training, structure, and socialization. In return, Milo will give you unwavering loyalty and love.Milo and his brother have come so far, and now he’s ready for the most important chapter—finding a forever home where he will be safe, loved, and never overlooked again.If you’re ready to give a deserving pup a second chance, Milo may be your perfect match.📍 Located in Texas – can be transported once adopted. Transport fee is $270–$300.📝 Apply here:https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41*Disclaimer: This pet is located in Texas. Once adoption is finalized the pet will be transported to the adopters location for an additional fee (currently $300).* The adoption fee helps to cover some of the cost of vetting the animal prior to adoption (spay/neuter, microchipping, and up to date vaccinations).Please fill out an adoption application to be considered for adoption. https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41

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Photo of Bella

Bella

Great Dane Mastiff

Female, Young
Thornton, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Bella is an amazing dog, very friendly, sweet, and well trained. She loves walks and playing with toys. She loves the groomer and is very easy going. My husband has been diagnosed with cancer and we cannot take care of her the way she needs. We are looking for a good home with lots of love and a yard for her to enjoy!

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Photo of Angel

Angel

Great Dane Collie

Female, 8 yrs 6 mos
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Angle is a 4.5 Year Old Great Dane/Smooth Coated Collie Mix. She loves playing with other dogs and ignores cats, unless they want to play. She loves her people and even though she loves playing with other dogs, she really wants her human all to herself. She is also laid back and enjoys a good cuddle and chill on the couch while catching up on some TV. Angle is crate trained, enjoys toys and completely untrustworthy on free roam with high interest items (this includes expensive items; we don’t know how she knows – but she does!) If you think you are Angle's forever home, please complete an adoption application at https://www.savethegiants.com/adoption-process .

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Photo of MEME

MEME

Great Dane Dutch Shepherd

Female, 1 yr 1 mo
Denver, CO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
-

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Photo of MAXIE

MAXIE

Great Dane Australian Shepherd

Female, 3 yrs 9 mos
Denver, CO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Adoption event ! November 2, 2-5pm SUNLIFE 333 N Green St Unit 75 Chicago, IL 60607 United States This pet and others will be available for adoption. Please submit your application prior to the event !

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Or, how about these Great Danes in cities near Denver, Colorado

These Great Danes are available for adoption close to Denver, Colorado.
Photo of Chevy

Chevy

Great Dane

Female, Adult
Lakewood, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
For more information about this Dane, please visit our website at https://rmgreatdane.org. Adoption Applications link can be found on the home page. Meet Chevy   Status: Available Sex: Spayed Female – Gastropexied Color: Merle    Ears: Natural Age: 6 yrs  Weight: 108 lbs Great Dane Experience Required Adoption Fee – has been paid by a generous sponsor   Chevy is a beautiful 6-year-old merle Great Dane looking for a special home that understands her needs and is ready to help her continue building confidence. At her core, Chevy is an incredibly loyal Dane who forms deep bonds with her people. Once she trusts you, she'll happily follow you from room to room, curl up nearby while you relax, and remind you why Great Danes are known for their devotion. She loves playing fetch with her Kong stick, zooming around the yard, and soaking up time with her favorite humans. Chevy is house-trained, crate-trained, knows basic commands including sit, down, come, stay, and off, and responds well to hand signals. She enjoys learning, especially when rewarded with her favorite all-natural treats. While Chevy has many wonderful qualities, she is looking for a very specific home where she can thrive. Chevy can be reactive to people and animals she sees through windows, on walks, or while riding in the car. She will bark and lunge when triggered and will need continued training, patience, and consistent leadership to help her work through these behaviors. Because of her reactivity, Chevy must be the only pet in the home. She is not a candidate for homes with other dogs, cats, or small animals. She also requires an adult-only home with no children. Chevy's ideal adopter will have previous giant breed experience, understand canine body language, and be committed to continuing her training and confidence-building. She would do best in a calm, predictable environment with a securely fenced yard where she can safely run and play. In return, Chevy offers unwavering loyalty, affection, and companionship. She settles in quickly with her people, enjoys spending time with her family, and loves nothing more than being close to the person she trusts. If you're an experienced giant breed owner looking for a devoted companion and are willing to provide the structure and training Chevy needs, she may be the perfect addition to your family. More about Chevy: Great Dane Experience Required Housetrained:Yes Crate trained: Yes Needs a calm home - dog savvy adults and teens only No dogs No cats Reactive to new people and dogs Professional training in process and will need to be continued Fearful and anxious around new people - needs slow introductions   July 25, 2026, 12:12 am

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Photo of Milo

Milo

Great Dane Mixed Breed (Medium)

Male, 8 mos
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
🐾 Meet Milo — A Resilient Sweetheart Ready for His Fresh Start! 🐾Milo is a 6-month-old Cane Corso mix puppy with a heart full of love and a story of resilience. He and his brother were rescued from a neglect situation, but despite his rough beginning, Milo has proven to be incredibly sweet, gentle, and eager to trust again.This handsome boy is still very much a puppy—playful, curious, and learning about the world around him. He’s already showing how smart and attentive he is, and with continued guidance, he’s going to grow into a loyal, devoted companion. Milo loves attention, enjoys playtime, and is happiest when he’s near his people.As a Cane Corso mix, he will likely grow into a large, strong dog, so he’s looking for a home that understands big breeds and is committed to training, structure, and socialization. In return, Milo will give you unwavering loyalty and love.Milo and his brother have come so far, and now he’s ready for the most important chapter—finding a forever home where he will be safe, loved, and never overlooked again.If you’re ready to give a deserving pup a second chance, Milo may be your perfect match.📍 Located in Texas – can be transported once adopted. Transport fee is $270–$300.📝 Apply here:https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41*Disclaimer: This pet is located in Texas. Once adoption is finalized the pet will be transported to the adopters location for an additional fee (currently $300).* The adoption fee helps to cover some of the cost of vetting the animal prior to adoption (spay/neuter, microchipping, and up to date vaccinations).Please fill out an adoption application to be considered for adoption. https://service.sheltermanager.com/asmservice?account=ch2817&method=online_form_html&formid=41

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Photo of Bella

Bella

Great Dane Mastiff

Female, Young
Thornton, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Bella is an amazing dog, very friendly, sweet, and well trained. She loves walks and playing with toys. She loves the groomer and is very easy going. My husband has been diagnosed with cancer and we cannot take care of her the way she needs. We are looking for a good home with lots of love and a yard for her to enjoy!

Learn More

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Photo of Stuart

Stuart

Great Dane Weimaraner

Male, 5 yrs 11 mos
Littleton, CO
Size
(when grown) -
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
HOMEOWNERSHIP REQUIRED! Attention LARGE dog lovers!!!  Please meet Stuart (not so little)! Don't let his sleek grey coat, soft floppy ears, and stunning hazel eyes distract you. Stuart may look like a striking and refined pedigree, but in reality, he's a big goofball!  Stuart thinks he will fit perfectly into any lap and looks for opportunities to make that happen! Stuart has wonderful obedience skills (sit, stay, shake, down, come, leave it and place) - He is very smart, always eager to please and very treat motivated.  He is fully house trained, crate trained and also has wonderful leash manners. Stuart loves to play with most other dogs (following proper introductions), loves children and has successfully resided with a feline.  Due to his size and energy level during play, Stuart would likely do best with medium to larger dogs (smaller dogs tend to be intimidated by his size) and should be supervised around younger children - he loves to gallop in the yard or during feeding time and may, accidentally, fail to notice a smaller child in his excitement. Having come from a less than desirable home situation, new surroundings, crowded places, and some new new people may make Stuart a bit nervous from time to time.  But, he has had the opportunity to work with his foster family in these areas to create positive associations and has made wonderful strides - he now rewards his foster family with endless belly rubs and voluntarily offers his paw for a shake!  He has gained confidence in meeting new people with just a little bit of structure and reassurance from those he trusts.  Stuart has so much love to give - if you apply to meet sweet Stuart today, you will not be disappointed! Adoption fee includes the following: Spay/Neuter Rabies Vaccination Distemper / Parvo Vaccines (includes series of 3 for puppies) Bordetella Microchip with prepaid lifetime registration Deworming ##839726##

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Photo of Angel

Angel

Great Dane Collie

Female, 8 yrs 6 mos
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Angle is a 4.5 Year Old Great Dane/Smooth Coated Collie Mix. She loves playing with other dogs and ignores cats, unless they want to play. She loves her people and even though she loves playing with other dogs, she really wants her human all to herself. She is also laid back and enjoys a good cuddle and chill on the couch while catching up on some TV. Angle is crate trained, enjoys toys and completely untrustworthy on free roam with high interest items (this includes expensive items; we don’t know how she knows – but she does!) If you think you are Angle's forever home, please complete an adoption application at https://www.savethegiants.com/adoption-process .

Learn More

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Photo of MEME

MEME

Great Dane Dutch Shepherd

Female, 1 yr 1 mo
Denver, CO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
-

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These pups are in Denver, Colorado too!

Below are our newest added Great Danes available for adoption in Denver, Colorado. To see more adoptable Great Danes in Denver, Colorado, use the search tool below to enter specific criteria!
Photo of Hazel

Hazel

Anatolian Shepherd

Female, 1 yr 6 mos
Littleton, CO
Size
(when grown) -
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hazel has been waiting patiently for the right family—and we think she's more than worth the wait. Hazel has been in foster care longer than she deserves. She was surrendered by her original owner and later thought she'd found her forever home, but due to severe dog allergies that developed in one of the children, her foster family was no longer able to keep any of their pets. Through it all, Hazel has remained the same sweet, loving dog. Since moving to her current foster home, Hazel has settled in beautifully. She's been especially gentle with children in all of the homes she's stayed in and loves being part of the family's daily routine. Hazel is a true velcro dog who wants to be wherever her people are. She'll happily follow you from room to room, and despite her size, she's convinced she's a lap dog. She loves long walks, playing with her foster's large male dog, squeaky balls, and just about any chew toy. She plays hard, naps even harder, and her little nub tail is always wagging when she's happy. She's incredibly smart, eager to learn, and enjoys having a job to do. One of the things that makes Hazel so special is her unique heritage. She's a mix of livestock guardian breeds, including Central Asian Ovcharka, Anatolian Shepherd, Taigan, and more. These breeds are known for being loyal, intelligent, and deeply devoted to their families. They also tend to be naturally observant and a bit reserved with new people, so it's perfectly normal for Hazel to take a little time to warm up. Like many guardian breeds, she'll happily let you know when someone is at the door, but once she knows you're part of her circle, she's affectionate, goofy, and incredibly loyal. She's made wonderful progress in foster and continues to grow more confident every day. Hazel would do best with an active family, a large male dog to be her playmate, someone who is home much of the day, and people who will give her a little time to settle into a new routine. In return, you'll have a constant companion who will make you laugh, keep you company, and love you wholeheartedly. Hazel has been waiting for the right match, not just the next one. If you're looking for a loyal best friend with a big heart and an even bigger personality, Hazel might just be your girl. ##2644330##

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Denver, Colorado.

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Related breeds in Denver, Colorado

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Great Dane shelters & rescues in Denver, Colorado

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Denver, Colorado. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

3.8 miles

Rocky Mountain Great Dane Rescue, Inc

PO Box 280368, Lakewood, CO 80228

Pet Types: dogs

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Rescue

4.4 miles

Sam Coffey Animal Rescue Friends - CO Transport Stop

ALL OF COLORADO STATE, Denver, CO 80204

Pet Types: cats, dogs

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Rescue

12 miles

2 Blondes All Breed Rescue

Littleton, CO 80126

Pet Types: dogs

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Rescue

13.4 miles

Save The Giants

Denver, CO 80014

Pet Types: dogs

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Rescue

13.4 miles

Blues City Animal Rescue -DENVER, CO- Transport Stop

Denver, CO 80014

Pet Types: dogs

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Rescue

22.9 miles

Colorado Puppy Rescue

18741 E Ponderosa Dr, Suite D, Parker, CO 80134

Pet Types: dogs

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Rescue

31.6 miles

Desiderata Rescue - West Transport

Ft Lupton, CO 80621

Pet Types: cats, dogs

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Shelter

31.6 miles

Soul Dog Rescue

1245 Factory Circle, Fort Lupton, CO 80621

Pet Types: cats, dogs

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Rescue

32.5 miles

Hope For Animals-Clear Creek Rescue

POB 63, Georgetown, CO 80444

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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