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Neapolitan Mastiff puppies and dogs in Berkeley, Missouri

Looking for a Neapolitan Mastiff puppy or dog in Berkeley, Missouri? Adopt a Pet can help you find an adorable Neapolitan Mastiff near you.

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Adopt a Neapolitan Mastiff near you in Berkeley, Missouri

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These Neapolitan Mastiffs are available for adoption close to Berkeley, Missouri.
Photo of Guido

Guido

Neapolitan Mastiff

Male, Adult
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website.Please meet our handsome mahogany boy GUIDO.  His coloring is the rarest in the Neapolitan Mastino Breed.  Guido and Gino were found roaming in Texas months back.  Right before their fate was about to end a local rescue pulled them not knowing what breed they really were.  Guido is well socialized, walks great on leash, is house trained and crate trained.  He is believed to be approximately 4 to 5 years old.  Guido is basically an easy gentlemen that just wants to be close to his humans and a soft bed to crash on.  If you are interested in Guido please go to our website at Mastino-Rescue-Inc.org and complete a family profile.  Or you can drop us an email at Mastinorescueinc@gmail.com with any questions.  Visit this organization's web site to see any additional information available about this pet.March 10, 2026, 12:07 am
Photo of Gracie

Gracie

Neapolitan Mastiff

Female, Adult
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained,
Story
You can fill out an adoption application online on our official website.Gracie came to us from an Arkansas Shelter basically at the same time as Adolfo.  She was also severely underweight and heartworm positive.  Gracie has successfully completed her heartworm treatment and has been spayed. Gracie wishes to be the only pet in the home and there seems to be no negotiating on that front from her.  She requests the full attention of her humans.  On the plus side, she loves car rides and won't leave your side whether she is on or off leash. She never disappoints! If you believe you are the perfect match for our beautiful approximately 5 year old girl, Gracie, please go to our website at mastino-rescue-inc.org and complete a family profile. Visit this organization's web site to see any additional information available about this pet.March 10, 2026, 12:07 am
Photo of Anita

Anita

Neapolitan Mastiff

Female, Adult
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website.Miss Anita found herself abandoned in her owner's garage when they moved.  Several neighbors  rallied around her to help her find a new home and family. A couple took her in to try and find her the right home on social media. That didn't work, so they reached out to Mastino Rescue, Inc., to help and find her a home. Anita has been spayed and on 8/13/24 she had her cherry eye surgery removal.  Anita is a great girl, loves her previous male foster but it took a couple days for her to warm up to her previous female foster.  She will need decompression time to settle into a new home successfully.  After slow introductions, she did start playing with her male foster Neo brother when she was in Arizona.  If you are looking for a beautiful tawny girl and have the time/patience for Anita, please go to our website at Mastino-rescue-inc.org and complete a family profile.  Anita is currently in boarding in Missouri.Visit this organization's web site to see any additional information available about this pet.March 10, 2026, 12:07 am
Photo of Gianna

Gianna

Neapolitan Mastiff

Female, Young
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
You can fill out an adoption application online on our official website.We partnered with Bull Mastiff Rescuers Inc. who saved this unique beauty from being passed around in Michigan. Her double cherry eye has been removed and spay completed, so she is set to find a loving foster home with someone experienced in caring for Neos. She did just have TPLO surgery in December 2025 and is healing well! We know Gianna plays well with another large male dog previously and has been doing well with slow introductions to new people. She’s a sweet girl, and we’re committed to finding the perfect match for her.  Are you ready to give her the love and care she deserves?Visit this organization's web site to see any additional information available about this pet.March 10, 2026, 12:07 am
Photo of Adolfo

Adolfo

Neapolitan Mastiff Cane Corso

Male, Young
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.Adolfo came to us after being surrendered to an Arkansas shelter.  He is currently being boarded in Missouri and is a VERY active and playful boy.  He is believed to be 3 years old or younger.  His wonderful boarding staff has put much needed weight on him.  His perfect home would have a large 6 foot fenced yard.  Adolfo would prefer to be the only pet in the home.   If you would like to know more about his happy, beautiful Neo boy, please go to our website and complete a family profile at mastino-rescue-inc.org.  Assistance with transport can be available to the perfect forever home.  Visit this organization's web site to see any additional information available about this pet.March 10, 2026, 12:07 am
Photo of Amara

Amara

Neapolitan Mastiff

Female, Young
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Amara is a stunning blue girl, ~20 months old, who came to rescue from a home in rural Northwest Arkansas. With the help of our amazing rescue partners and generous donors, she has now received the care she desperately needed—including spay surgery and corrective cherry eye surgery that restored her sight! Amara has healed beautifully and is now ready to begin her next chapter. We’re so grateful to everyone who helped give this sweet girl a brighter future. Amara is currently looking for her forever home.  ADULTS ONLY, BREED EXPERIENCE, ONLY PET IN HOME.  Visit this organization's web site to see any additional information available about this pet.March 10, 2026, 12:07 am

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Related breeds in Berkeley, Missouri

Neapolitan Mastiff shelters & rescues in Berkeley, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Neapolitan Mastiff puppies in Berkeley, Missouri. Browse these Neapolitan Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

11.2 miles

Mastino Rescue, Inc.

St. Louis, MO 63301

Pet Types: dogs

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Want to learn more about adopting a Neapolitan Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Neapolitan Mastiff puppy. Check out the links below for everything you ever wanted to know about Neapolitan Mastiff puppies and adults.

Neapolitan Mastiff basics

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Where do Neapolitan Mastiffs come from? How many types of Neapolitan Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Neapolitan Mastiff.

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