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Great Dane puppies and dogs in Middletown, Delaware

Looking for a Great Dane puppy or dog in Middletown, Delaware? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Middletown, Delaware

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These Great Danes are available for adoption close to Middletown, Delaware.
Photo of Evo

Evo

Great Dane

Female, 5 yrs
Dover, DE
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Meet Evo! This friendly 96-pound extra-large dog is looking for her forever home after her owner could no longer care for her. She is bonded with her best friend, Yamper! Come meet them today!*This pet qualifies for our Sponsored by Simba Program: Pets for Veterans: no adoption fee for any military veteran adopting a pet 1yo+.*This pet is available at:Brandywine Valley SPCA1757 Horsepond RdDover DE 19901
Photo of Lady Raven

Lady Raven

Great Dane

Female, Adult
Linwood, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with dogs, Good with cats, Needs experienced adopter, House-trained,
Story
This is Lady Raven. She goes by Lady. She is a sweetheart and is content to just lay on the couch with you all day. She is very skittish though with certain objects and is scared of my neighbor’s umbrella or other objects. She lives with three children and two cats. She could be good with other dogs with a proper introduction and experienced person. Unfortunately I have not had the funds to get her fixed yet and she is due for shots. I know this may deter a lot of people but I am hoping someone is willing to help. Comes with crate, food bowls, food, toys and other things. She deserves a home where people are home more often the time.
Photo of Charlie

Charlie

Great Dane

Male, 2 yrs
Media, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Kane aka Charlie is a giant marshmallow…….. Kane loves to veg out with his pals (fur and human). He gets along amazingly great with everyone. This 2-year-old dude is looking for a chill crew to hang with. He is available for adoption. If you're cool with a laid-back buddy, hit us up and fill out an application today at www.hindeanimalrescueteam.org
Photo of Regan

Regan

Great Dane

Female, 2 yrs 4 mos
Newfield, NJ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Welcome Regan to 4 Paws! Bonus to any spooky movie buffs if you can guess who she is named after ????!This Great Dane was surrendered due to the family not having enough time. She’s a big, beautiful and goofy gal! She is housebroken and crate trained. Regan does well with some dogs but may be best as an only dog (meet and greet with any dogs would be required prior to approval). Regan does well with cats. She will need a home willing and able to provide her the structure, rules and boundaries needed to thrive. Large breed experience encouraged! PLEASE READ:The beginning of our application form states what our adoption service area is, once you apply you will receive an email explaining next steps.
Photo of Athena

Athena

Great Dane Great Pyrenees

Female, Puppy
Exton, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   July 17, 2026, 5:26 pm
Photo of Donald

Donald

Great Dane Great Pyrenees

Male, Puppy
Exton, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   July 17, 2026, 5:26 pm

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Great Dane shelters & rescues in Middletown, Delaware

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Middletown, Delaware. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Shelter

24.8 miles

Brandywine Valley SPCA - Dover

1757 Horsepond Road, Dover, DE 19901

Pet Types: cats, dogs

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Rescue

33.4 miles

Hinde's Animal Rescue Team

65 S Pennell Road, Media, PA 19063

Pet Types: cats, dogs, farm animals, rabbits, small animals

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Rescue

37.7 miles

4 Paws Dog Rescue of NJ

Newfield, NJ 08344

Pet Types: dogs

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Rescue

38.6 miles

Mastiffs to Mutts - Eastern PA

Exton, PA 19341

Pet Types: dogs

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Rescue

39.5 miles

All 4 Paws Rescue

Malvern, PA 19355

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

46.8 miles

The Pennsylvania SPCA

350 E. Erie Avenue, Philadelphia, PA 19134

Pet Types: cats, dogs, farm animals, horses

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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