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Mastiff puppies and dogs in Simi Valley, California

Looking for a Mastiff puppy or dog in Simi Valley, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Simi Valley, California Other pups in Simi Valley, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Simi Valley, California Mastiff shelters and rescues in Simi Valley, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Simi Valley, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Simi Valley, California

These Mastiffs are available for adoption close to Simi Valley, California.
Needs Home Fast
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FREDA

Mastiff

Female, 2 yrs 3 mos
Chatsworth, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
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NALA

Mastiff Rhodesian Ridgeback

Female, Young
Woodland Hills, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Meet Nala – A Gentle Soul with a Heart of Gold Nala is a beautiful Boerboel/Rhodesian mix with a heart just as big as her smile. Rescued from Stanislaus Animal Services, she’s been given a second chance—and now she’s ready to find the forever home she truly deserves. At around 3 years old and 65 lbs, Nala is the perfect mix of playful, affectionate, and loving. She’s spayed, fully vaccinated, and microchipped—completely ready to start her next chapter. Nala absolutely loves being around people and thrives on companionship. She has a sweet and loving nature and gets along well with other dogs, making her a wonderful fit for many homes. She’s currently working with trainers and continuing to build confidence and social skills—showing every day just how much potential she has to be an incredible lifelong companion. All Nala needs now is someone to give her the love and stability she’s been waiting for.  Nala is available for: • Adoption • Foster-to-Adopt If you’re ready to open your heart to a loyal, loving dog, Nala is ready to meet you. Please contact the rescue for more information and to schedule a meet-and-greet.                         June 18, 2026, 11:15 pm

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TATER-TOT

Mastiff

Male, 3 yrs
Castaic, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
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*NAGEE

Mastiff Boxer

Male, 6 yrs 1 mo
Camarillo, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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Needs Home Fast
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MOUSE

Mastiff Great Dane

Male, 3 yrs 2 mos
Van Nuys, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
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Kylo

Mastiff American Pit Bull Terrier

Male, 4 yrs 8 mos
Santa Paula, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Meet KyloKylo is a Mastiff mix who was surrendered at just 14 months old by the only family he had ever known. Having lived outside his entire life, Kylo is now working through fear and behavioral challenges that stem from his past experiences. While his start in life was difficult, his past does not define his future.Kylo is a highly intelligent dog and already knows several commands, including Place, Sit, Wait, Easy, and Come. He responds best to clear structure, consistency, and calm handling.Kylo is uncomfortable with strangers and can be dog reactive, requiring careful management around other dogs. He has successfully shared a play yard with another dog while wearing a muzzle, showing that with proper structure and supervision, controlled dog interactions are possible.Kylo is seeking a quiet, adult-only home with no children. He needs an experienced adopter who understands fear-based behaviors and is committed to continued training and behavior work. Slow introductions, patience, and a predictable environment will be essential for his success.Once Kylo builds trust, he forms deep bonds and is intensely loyal to his people. In the right home, he has the potential to become a devoted and rewarding companion.At SPARC, we believe in No Kill, No Excuses, and we are fully committed to Kylo. He is looking for someone willing to give him the time, understanding, and compassion he deserves.For more information or to meet Kylo, please contact SPARC. 805-525-8609

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Simi Valley, California.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Agoura Hills, CA Mastiff in Beverly Hills, CA Mastiff in Burbank, CA Mastiff in Calabasas, CA Mastiff in Camarillo, CA Mastiff in Culver City, CA Mastiff in El Segundo, CA Mastiff in Fillmore, CA Mastiff in Glendale, CA Mastiff in Hawthorne, CA Mastiff in Hermosa Beach, CA Mastiff in Inglewood, CA Mastiff in La Canada Flintridge, CA Mastiff in Lawndale, CA Mastiff in Los Angeles, CA Mastiff in Malibu, CA Mastiff in Manhattan Beach, CA Mastiff in Moorpark, CA Mastiff in Ojai, CA Mastiff in Oxnard, CA Mastiff in Pasadena, CA Mastiff in Port Hueneme, CA Mastiff in San Fernando, CA Mastiff in Santa Clarita, CA Mastiff in Santa Monica, CA Mastiff in Santa Paula, CA Mastiff in Thousand Oaks, CA Mastiff in Ventura, CA Mastiff in West Hollywood, CA Mastiff in Westlake Village, CA

Related breeds in Simi Valley, California

Bullmastiffs in Simi Valley, California Neapolitan Mastiffs in Simi Valley, California Saint Bernards in Simi Valley, California

Mastiff shelters & rescues in Simi Valley, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Simi Valley, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

8.9 miles

West Valley Animal Care Center - Los Angeles Animal Services

20655 Plummer Street, Chatsworth, CA 91311

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

10.5 miles

Melita's Dream Animal Rescue

21200 Oxnard St, #6492, Woodland Hills, CA 91365

Pet Types: dogs

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Shelter

15.2 miles

Los Angeles County: Santa Clarita Valley (Castaic)

31044 N. Charlie Canyon Rd., Castaic, CA 91384

Pet Types: cats, dogs, rabbits, small animals

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Shelter

15.6 miles

Ventura County Animal Services

600 Aviation Drive, Camarillo, CA 93010

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

18 miles

East Valley Animal Care Center - Los Angeles Animal Services

14409 Vanowen Street, Van Nuys, CA 91405

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

19.6 miles

Santa Paula Animal Rescue Center

705 E. Santa Barbara Street, Santa Paula, CA 93060

Pet Types: cats, dogs, rabbits, small animals

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Rescue

20.5 miles

Lost and Found Dogs USA Network - Santa Clarita

19059 Golden Valley Way, Canyon Country, CA 91387

Pet Types: cats, dogs, farm animals

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Rescue

20.5 miles

Hank's Legacy Foundation

canyon country, CA 91387

Pet Types: cats, dogs

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Rescue

22.7 miles

Philozoia Animal Rescue

Santa Monica, CA 90401

Pet Types: dogs

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Shelter

23.1 miles

Best Friends Pet Adoption Center - West LA

1845 Pontius Ave, Los Angeles, CA 90025

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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