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Mastiff puppies and dogs in Des Moines, Iowa

Looking for a Mastiff puppy or dog in Des Moines, Iowa? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Des Moines, Iowa Other pups in Des Moines, Iowa Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Des Moines, Iowa Mastiff shelters and rescues in Des Moines, Iowa Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Des Moines, Iowa

These Mastiffs are available in Des Moines, Iowa.
Photo of Finn AKA Gage JuM

Finn AKA Gage JuM

Mastiff Shepherd (Unknown Type)

Male, 7 yrs 8 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Finn may look like a rockstar with his striking Mastiff–Shepherd good looks, but at heart, he’s a big, soft lovebug. Weighing in at about 60 pounds, Finn has grown into a handsome boy with a beautiful gray and tan coat, soulful eyes, and an even bigger personality. Despite his star-quality appearance, Finn is more of a laid-back, easygoing guy—think Eeyore vibes, but with engines revved and ready to love. From the moment he wakes up, he’s prepared to shower his people with affection… and trust us, it’s A LOT of love! Finn does well with other dogs and does need a slow, proper introductions to new friends—both two-legged and four-legged. Once he knows you, he loves you deeply. He’s happiest when he has a buddy (human or canine) to share his world with. Affection is Finn’s specialty. When someone comes to greet him, he lights up, runs over with enthusiasm, and hands out slobbery kisses and big hugs like they’re backstage passes. His joy is genuine, his heart is huge, and he’s always thrilled to see his people. If you’re looking for a big, lovable, slightly goofy rockstar who will adore you endlessly, Finn is ready to take center stage in your heart. Local adoption only $300 (in TX)

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Photo of Luke AG

Luke AG

Mastiff American Pit Bull Terrier

Male, 4 yrs 8 mos
Clive, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $300(in TX) Out of state adoption fee is $550 (includes transport to your area)

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Photo of Diego JuM

Diego JuM

Mastiff Mixed Breed (Large)

Male, 2 yrs 3 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
I'm Diego, a striking 2-year-old chocolate and blond brindle Mastiff mix, and I've got the heart of an adventurer! 🐕 At 63 pounds of pure energy and loyalty, I'm already neutered and crate trained—ready to be your partner in crime. I thrive with active owners who can match my enthusiasm, and I'm fantastic with other dogs, so playdates are always a go! If you're looking for a friendly, energetic companion who'll stick by your side through thick and thin, come meet me today. 💪❤️ Local adoption fee is $300 (in TX) Out of state adoption fee is $550 (includes transport to your area)

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Or, how about these Mastiffs in cities near Des Moines, Iowa

These Mastiffs are available for adoption close to Des Moines, Iowa.
Photo of Finn AKA Gage JuM

Finn AKA Gage JuM

Mastiff Shepherd (Unknown Type)

Male, 7 yrs 8 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Finn may look like a rockstar with his striking Mastiff–Shepherd good looks, but at heart, he’s a big, soft lovebug. Weighing in at about 60 pounds, Finn has grown into a handsome boy with a beautiful gray and tan coat, soulful eyes, and an even bigger personality. Despite his star-quality appearance, Finn is more of a laid-back, easygoing guy—think Eeyore vibes, but with engines revved and ready to love. From the moment he wakes up, he’s prepared to shower his people with affection… and trust us, it’s A LOT of love! Finn does well with other dogs and does need a slow, proper introductions to new friends—both two-legged and four-legged. Once he knows you, he loves you deeply. He’s happiest when he has a buddy (human or canine) to share his world with. Affection is Finn’s specialty. When someone comes to greet him, he lights up, runs over with enthusiasm, and hands out slobbery kisses and big hugs like they’re backstage passes. His joy is genuine, his heart is huge, and he’s always thrilled to see his people. If you’re looking for a big, lovable, slightly goofy rockstar who will adore you endlessly, Finn is ready to take center stage in your heart. Local adoption only $300 (in TX)

Learn More

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Photo of Luke AG

Luke AG

Mastiff American Pit Bull Terrier

Male, 4 yrs 8 mos
Clive, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $300(in TX) Out of state adoption fee is $550 (includes transport to your area)

Learn More

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Photo of Diego JuM

Diego JuM

Mastiff Mixed Breed (Large)

Male, 2 yrs 3 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
I'm Diego, a striking 2-year-old chocolate and blond brindle Mastiff mix, and I've got the heart of an adventurer! 🐕 At 63 pounds of pure energy and loyalty, I'm already neutered and crate trained—ready to be your partner in crime. I thrive with active owners who can match my enthusiasm, and I'm fantastic with other dogs, so playdates are always a go! If you're looking for a friendly, energetic companion who'll stick by your side through thick and thin, come meet me today. 💪❤️ Local adoption fee is $300 (in TX) Out of state adoption fee is $550 (includes transport to your area)

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These pups are in Des Moines, Iowa too!

Below are our newest added Mastiffs available for adoption in Des Moines, Iowa. To see more adoptable Mastiffs in Des Moines, Iowa, use the search tool below to enter specific criteria!
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Photo of Truly JuM

Truly JuM

Australian Shepherd St. Bernard

Female, 2 yrs 6 mos
Clive, IA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Hi, I'm Truly JuM 🐾, a 2-year-old red/mahogany and white Australian Shepherd with a Saint Bernard in my background! At about 53 pounds, I'm a medium girl with a striking bicolor coat, and I'm already spayed. I'm affectionate, loyal, and smart, I'm crate trained, and I get along well with children and other dogs 💕. I need an active lifestyle, so I'll be happiest with a family ready to keep up with my adventurous, playful side 🌲. Come meet me and see how cuddly and friendly I can be. I'd love to be your next adventure partner! ❤️ Local adoption fee is $300 (in TX) Out of state adoption fee is $550 (includes transport to your area)

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Des Moines, Iowa.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Des Moines, Iowa

Bullmastiffs in Des Moines, Iowa Neapolitan Mastiffs in Des Moines, Iowa Saint Bernards in Des Moines, Iowa

Mastiff shelters & rescues in Des Moines, Iowa

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Des Moines, Iowa. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

6 miles

God's Dogs Rescue of TX for IA Transport Stop

Clive, IA 50325

Pet Types: dogs

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If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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