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Mastiff puppies and dogs in Iowa

Looking for a Mastiff puppy or dog in Iowa? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Iowa

Below are our newest added Mastiffs available for adoption in Iowa. To see more adoptable Mastiffs in Iowa, use the search tool below to enter specific criteria!
We'll also keep you updated on Ralph BW's adoption status with email updates.
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Ralph BW

Mastiff/Mixed Breed (Large)

Male, 1 yr 1 mo
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats,
Story
Ralph the Derp! Ralph is a huge friendly, enthusiastic, uncoordinated 4-legged energetic goofball! He was rescued from “death row” at a high kill shelter, as a skinny stray with a treatable skin condition. His fur has almost completely grown in & he is now at a healthy weight. This overgrown mastiff/Cane Corso mix pup has no comprehension of his size, leaning into humans for affection or trying to ooze onto laps for cuddles. He is being trained not to jump and not to paw for attention/affection/play because he currently has 85# of mass behind those “congenial” moves. Ralph plays well with dogs of all sizes, but would do best with med-to-larger dogs due to his size & poorly curbed gusto. He hordes toys, taking them all to his chosen dog bed of the day. He likes to carry a special toy “baby” in his mouth when going out in the yard. He does need to be fed in his crate & will guard his empty food bowl from other dogs, unless he is distracted with a toy & led outdoors after meals. He is great on a leash, makes awesome grunty sounds when cuddled, enjoys baths. Ralph will make a great addition to an active family with older children. He is eager to please, food and affection oriented (although a bit stubborn at times), making him an ideal candidate for success with continuation of his training. Please consider adopting the gorgeous big derp into your home. Attributes: In training to avoid jumping/pawing Active family Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)
We'll also keep you updated on Tank's adoption status with email updates.
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Tank

Mastiff

Male, 7 yrs
Ottumwa, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
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We'll also keep you updated on Princess's adoption status with email updates.
Photo of Princess

Princess

Mastiff/German Shepherd Dog

Female, Young
Ames, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Hello everyone! Her name is Princess, my daughter picked it out! We got her from a friend when she was a very tiny puppy, and momma and papa dog had a large liter! Princess's birthday is December 12th, so she is just over 3 years old now! She is a Mastiff, German Shephard Mix is what we were told the parents were. Princess is great with kids of all ages, and other pets indoor and outdoor! Also cats or dogs! Currently she lives with a family friend and does wonderful with their kids, and cats! Princess loves to go on walks, and run around! An ideal place for her is somewhere she can get some exercise! Whether that means yard or trips to a dog park, she loves both! Princess is kennel trained, and house trained, meaning she can stay in or out of kennel when family isn't home! Her temperament is very friendly, calm, chill, and likes to take her naps too! She is also a curious dog, and likes to look outside and watch the world go by!
We'll also keep you updated on Ziva's adoption status with email updates.
Photo of Ziva

Ziva

Mastiff/Boxer

Female, 1 yr 1 mo
Council Bluffs, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
Welcome to rescue, Ziva!  She is a mix of Mastiff/Boxer/Hound, born appx Feb 2025.  She is a smart girl and full of energy! She weighs 50 lbs. Ziva will curl up in your lap for naps. She does well on a leash for walks and likes puzzle games. She needs to be in a home with another dog to play with. Ziva came to Muddy Paws Parvo+.  She was treated and is a healthy girl! The suggested adoption donation for Ziva is $415, which includes a lifetime of free relationship-based training for any behavioral problems (not obedience training).  Muddy Paws is a 501c3 non-profit organization meaning that part of your donation MAY be TAX DEDUCTIBLE. We are a 100% volunteer rescue committed to giving animals a second chance at life. All donations go toward that mission. Adoption fees are the primary source of funding for the cost of veterinary care for our animals. In 2022 alone, we provided animal Healthcare totaling over $399,000 covered mainly through adoption fees. Information about the adoption process:  All adoptions require a completed ADOPTION APPLICATION. Once your application has completed our prescreen steps, we will put you in touch with the animal’s foster to see if you and the pet are a good match. If so, we will arrange a meeting for you and the animal. The adoptions for all of our animals will take place in the Omaha, NE area and must be done by the adoptive family in person. We do not ship or deliver. Please Note:  We are a RESCUE, which is different from a shelter. We conduct veterinary and personal reference checks, and a Home Visit (Virtual in some cases) during the application approval process. We always select the right applicant for each animal, based on the animal’s needs. If you and the animal are not a good match, we will help you select another animal, or we will keep your approved application on file for 6 months. To learn about Muddy Paws Second Chance Rescue or donate to our animals, please visit our website at MuddyPawsSecondChanceRescue.com or our Facebook Page Muddy Paws Second Chance Rescue Inc.   If the dog or cat you adopt is older than 6 months of age and not spayed or neutered, you will receive a voucher to alter the pet at Val Verde Animal Hospital in Omaha, at no cost to you.  Or you can alter the pet at your own vet and be reimbursed $100 for dogs, and $50 for cats, of total cost.  If the dog or cat is younger than 6 months of age, adopter will be responsible for the cost of altering the pet at the vet of their choice.  If proof of alter is received by Muddy Paws prior to the pet turning 6 months of age, a reimbursement of $100 for dogs and $50 for cats, will be sent to you to help cover expenses.  [Muddy Paws can also suggest a vet with a reduced cost for alters.]  All puppies and kittens MUST be spayed or neutered by 6 months of age.  All dogs and cats MUST be spayed or neutered no later than one month after adoption is finalized.  Thank you in advance for your compliance. ##2539859##
We'll also keep you updated on Big Momma's adoption status with email updates.
Photo of Big Momma

Big Momma

Mastiff

Female, Senior
Burlington, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids,
Story
Big Momma is a 5 year old female Mastiff. Big Momma is of course a big pretty gal, she is soft, and cuddly too. She is pretty good at moving around at her own speed..dont rush her lol, and just as funny as can be when she tilts her head at you. Just imagine laying your head next to hers... such a big face to gaze into! Her friend Sherry would love to go with her too, so please check her out, they are happily bonded together and we plan to keep it that way. She is not a fan of any other dogs but Sherry, Sherry is her one exception to her rule we have found. Our adoption hours are Tuesday-Friday 3-6PM and 1-5PM on the weekends. We are located in Burlington, Iowa. All dog adoptions include a health exam, Rabies, DHPP and Distemper vaccinations, Heartworm check, Sterilization and post surgical pain medication. All cat adoptions include A health check up, FLV and FiV screening, FVRCP and rabies vaccinations, sterilization with pain medications. Please visit our website desmoinescountyhumanesociety.org for more info on any pet listed or to view all of our adoptable pets.
We'll also keep you updated on Carver's adoption status with email updates.
Photo of Carver

Carver

Mastiff

Male, 4 yrs 4 mos
Fort Madison, IA
Size
(when grown) -
Details
-
Story
If you have ANY QUESTIONS or are truly interested in adopting any animal from PAW Animal Shelter Please, fillout an adoption application FIRST!   WE are a high intake No Kill Shelter ran by a staff of 4 and do not always have time to answer every question asked by so many. If you are a good fit for the animal you are interested in -we will call to speak with you, If we feel you are not a good fit , we will contact you about other pets that may be a good fit for your home. Many people are losing the opportunity to adopt the animal they want because they fail to put in an application and the pet was adopted before we could answer your email. .If you have applied for an animal in our facility and have not received a response within 7 days, PLEASE call or contact us again. Though we do our best in trying to answer all emails in a timely manner, sometimes things get away from us, get lost or misplaced. It is never our intention to ignore a request about an adoptable animal in our facility. Sandy Brown, Director, PAW Animal Shelter 319-372-2274 ##1849160##

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Iowa.

Mastiff puppies and dogs in Iowa cities

Mastiff Puppies near me Mastiff in Adel Mastiff in Algona Mastiff in Altoona Mastiff in Ames Mastiff in Anamosa Mastiff in Ankeny Mastiff in Atlantic Mastiff in Bettendorf Mastiff in Boone Mastiff in Burlington Mastiff in Carroll Mastiff in Cedar Falls Mastiff in Cedar Rapids Mastiff in Centerville Mastiff in Chariton Mastiff in Charles City Mastiff in Cherokee Mastiff in Clarinda Mastiff in Clear Lake Mastiff in Clinton Mastiff in Clive Mastiff in Coralville Mastiff in Council Bluffs Mastiff in Creston Mastiff in Davenport Mastiff in Decorah Mastiff in Denison Mastiff in Des Moines Mastiff in De Witt Mastiff in Dubuque Mastiff in Eldridge Mastiff in Estherville Mastiff in Evansdale Mastiff in Fairfield Mastiff in Fort Dodge Mastiff in Fort Madison Mastiff in Glenwood Mastiff in Grimes Mastiff in Grinnell Mastiff in Harlan Mastiff in Hiawatha Mastiff in Independence Mastiff in Indianola Mastiff in Iowa City Mastiff in Iowa Falls Mastiff in Johnston Mastiff in Keokuk Mastiff in Knoxville Mastiff in Le Mars Mastiff in Manchester Mastiff in Maquoketa Mastiff in Marion Mastiff in Marshalltown Mastiff in Mason City Mastiff in Mount Pleasant Mastiff in Muscatine Mastiff in Nevada Mastiff in Newton Mastiff in North Liberty Mastiff in Norwalk Mastiff in Oelwein Mastiff in Orange City Mastiff in Osceola Mastiff in Oskaloosa Mastiff in Ottumwa Mastiff in Pella Mastiff in Perry Mastiff in Pleasant Hill Mastiff in Red Oak Mastiff in Sheldon Mastiff in Shenandoah Mastiff in Sioux Center Mastiff in Sioux City Mastiff in Spencer Mastiff in Spirit Lake Mastiff in Storm Lake Mastiff in Urbandale Mastiff in Vinton Mastiff in Washington Mastiff in Waterloo Mastiff in Waukee Mastiff in Waverly Mastiff in Webster City Mastiff in West Des Moines Mastiff in Windsor Heights Mastiff in Winterset

Mastiff shelters & rescues in Iowa

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Iowa. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Heartland Humane Society

314 Fox-Sauk Rd, Ottumwa , IA 52501

Pet Types: cats, dogs

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Shelter

PAWS of Greene County

1700 Doreen Wilber Drive, Jefferson , IA 50129

Pet Types: cats, dogs

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Rescue

Animal Rescue of Carroll

1721 East 10th Street, Carroll , IA 51401

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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