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Mastiff puppies and dogs in Iowa

Looking for a Mastiff puppy or dog in Iowa? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Iowa

Below are our newest added Mastiffs available for adoption in Iowa. To see more adoptable Mastiffs in Iowa, use the search tool below to enter specific criteria!
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Photo of Tabby (aka Tabitha/Courtesy Post)

Tabby (aka Tabitha/Courtesy Post)

Mastiff

Female, 2 yrs 11 mos
Council Bluffs, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
House-trained,
Story
Meet our beautiful purebred Mastiff, Tabby.  At 3 years old - she is loyal, intelligent, affectionate, and true to the Mastiff breed in both devotion and protectiveness. She can be cautious with strangers at first, but once comfortable, she is a loving and deeply loyal companion. An owner with large breed experience is REQUIRED. Tabby would do best in a quieter home with a large yard wiith a privacy fence.  Because of her size, it is recommended no children.  She is truly a lovely dog looking for a calm, stable home with no other pets.  She's a fun and very lovable dog. She has been professionally trained in obedience.  She is house trained and very well mannered in the home.   The suggested adoption donation for Tabby is $450, which includes a lifetime of free relationship-based training for any behavioral problems (not obedience training).  Muddy Paws is a 501c3 non-profit organization meaning that part of your donation MAY be TAX DEDUCTIBLE. We are a 100% volunteer rescue committed to giving animals a second chance at life. All donations go toward that mission. Adoption fees are the primary source of funding for the cost of veterinary care for our animals. In 2022 alone, we provided animal Healthcare totaling over $399,000 covered mainly through adoption fees. Adoptions for Tabby is limited to the area within 50 miles of Omaha so that they can continue to take advantage of free training from our certified positive reinforcement trainers.       Information about the adoption process:  All adoptions require a completed ADOPTION APPLICATION. Once your application has completed our prescreen steps, we will put you in touch with the animal’s foster to see if you and the pet are a good match. If so, we will arrange a meeting for you and the animal. The adoptions for all of our animals will take place in the Omaha, NE area and must be done by the adoptive family in person. We do not ship or deliver. Please Note:  We are a RESCUE, which is different from a shelter. We conduct veterinary and personal reference checks, and a Home Visit (Virtual in some cases) during the application approval process. We always select the right applicant for each animal, based on the animal’s needs. If you and the animal are not a good match, we will help you select another animal, or we will keep your approved application on file for 6 months. To learn about Muddy Paws Second Chance Rescue or donate to our animals, please visit our website at MuddyPawsSecondChanceRescue.com or our Facebook Page Muddy Paws Second Chance Rescue Inc. If the dog or cat you adopt is older than 6 months of age and not spayed or neutered, you will receive a voucher to alter the pet at Val Verde Animal Hospital in Omaha, at no cost to you.  Or you can alter the pet at your own vet and be reimbursed $100 for dogs, and $50 for cats, of total cost.  If the dog or cat is younger than 6 months of age, adopter will be responsible for the cost of altering the pet at the vet of their choice.  If proof of alter is received by Muddy Paws prior to the pet turning 6 months of age, a reimbursement of $100 for dogs and $50 for cats, will be sent to you to help cover expenses.  [Muddy Paws can also suggest a vet with a reduced cost for alters.]  All puppies and kittens MUST be spayed or neutered by 6 months of age.  All dogs and cats MUST be spayed or neutered no later than one month after adoption is finalized.  Thank you in advance for your compliance. ##2749147##
Photo of Mazzy

Mazzy

Mastiff

Female, Adult
Cedar Rapids, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Mazzy was born 1/21/23. She is 50% mastiff, 32.6% pit bull, 10.7% bulldog, and 6.7% boxer. She loves all people and animals. Loves to play and is incredibly smart. She will pogo jump in front of you but never jumps on people and has never bit anyone. She loves cuddling with people and dogs, wants to play with willing cats but knows when to back off, and has learned how to be gentle with small children. She’s a great dog, rehoming due to relocating.
Photo of Bella

Bella

Mastiff/Mixed Breed (Medium)

Female, 1 yr 5 mos
Council Bluffs, IA
Size
(when grown) -
Details
-
Story
Meet Bella 🐾 Bella is an 11-month-old Mastiff mix with the sweetest personality. This happy, laid back girl is ready for just about anything — whether that’s joining you on outdoor adventures or curling up beside you on the couch for a lazy evening at home. When Bella first came to MHS, she was struggling with demodex and had significant hair loss. Thanks to the amazing care from the IWCC Vet Tech Program, Bella received the treatment and love she needed to feel like herself again. Now her fur is growing back, her confidence is shining, and she’s ready to find the forever family she deserves. Bella has already come so far — now all she needs is a home to call her own. Could that be with you?
Photo of Ella Mae

Ella Mae

Mastiff

Female, Adult
Cedar Rapids, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Good with dogs,
Story
You can fill out an adoption application online on our official website.Meet Ella Mae! Ella is a little shy when she first meets you, but give her just a little time and she'll come right out of her shell! Once she's comfortable, you'll see what a sweet, goofy girl she really is. At her heart, Ella is true to her breed mix (mastiff) and does have some strong personality traits. Ella Mae is still building her confidence and may startle if someone walks behind her or she steps on something crunchy, but she's making progress everyday. She loves exploring the yard and has even entertained herself with toys. Once she gets comfortable enough to play, she can get some serious zoomies and will happily give you a body slam! Ella has done wonderfully on group dog walks and greets other dogs nicely through the fence. We think she would thrive with a confident canine companion who can help show her the ropes, however she has shown us resource guarding tendencies with possessions. She has not yet been cat tested and would do best in a home without any children as she is still learning all about this big world we live in. Positive reinforcement and a little patience will go a long way with this sweet girl.  She walks beautifully on a leash and is food motivated when it comes to learning new training cues. One important note is that Ella Mae is quite the little escape artist and can clear a 5 foot fence with ease! Her future home will need at least a 6 foot privacy fence to keep this athletic girl safely contained.  Ella Mae's adoption fee is $250 and includes her spay, microchip, current vaccinations and preventatives, plus a free basic obedience course with Cedar Run Company in Hiawatha. Last Hope requires that all animals be kept as indoor only pets and that adopters have a history of having kept their pets altered and current on vaccinations and preventative care. Our adoption process includes a background check, home visit, and a vet history check. If you would like to meet Ella Mae, please submit an adoption application on our website, Adopthope.org.Visit this organization's web site to see any additional information available about this pet.November 2, 2026, 11:58 am
Photo of Diego JuM

Diego JuM

Mastiff/Mixed Breed (Large)

Male, 2 yrs 3 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
I'm Diego, a striking 2-year-old chocolate and blond brindle Mastiff mix, and I've got the heart of an adventurer! 🐕 At 63 pounds of pure energy and loyalty, I'm already neutered and crate trained—ready to be your partner in crime. I thrive with active owners who can match my enthusiasm, and I'm fantastic with other dogs, so playdates are always a go! If you're looking for a friendly, energetic companion who'll stick by your side through thick and thin, come meet me today. 💪❤️ Local adoption fee is $300 (in TX) Out of state adoption fee is $550 (includes transport to your area)
Photo of Apollo (Courtesy Post)

Apollo (Courtesy Post)

English Mastiff

Male, 4 yrs 3 mos
Council Bluffs, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
House-trained,
Story
Gentle Giant English Mastiff, 4 years old - sweet and cuddly.  Seeking adult/teen home with a strong owner who can handle his size and love him as much as his current family. Meet Apollo, a purebred English Mastiff looking for his forever home.  He is a very sweet, gentle-hearted boy who truly loves his people, but his size and clumsineess make him a poor fit for a home with small children.  A friendly "hello" from Apollo can easily knock a toddler or younger kid over.  He needs a home with adults or older kids (age 12+). Apollo's Personality and Daily Habits Calm and protective Would prefer not to share his toys or meals Stranger friendly Apollo is a big cuddler and a bit of a homebody.  He is not a high-energy dog: one walk a day is plenty for him.  The rest of the time, he is happiest sitting on your feet while you work or lounging on his bed nearby.  He'll get up occasionally to bop around outside or play with a toy, but he can be a little lazy and sometimes needs a gentle nudge to get moving. TRAINING Apollo has been professionally trained at All Dogs Unleashed and had a refresher course May 28th.  He walks fairly well and has good manners overall.  He is house trained and does not bark much.  Due to his size and strength, he does require a physically strong person to handle him!!!  On rare occasions, he may get excited if he sees a person or another dog and can try to take off.  His future owner needs to be comfortable handling a very strong dog. General Things to Know about APOLLO He is neutered, up-to-date on all vaccinations and has never had any serious health problems. As a giant breed, he does eat a lot and is more expensive to care for than a smaller dog.  His new family should be prepared for the financial commitment  that comes with a large Mastiff.  All of the AKC papers will be provided. THE PERFECT HOME Someone who will love and cherish him Someone with experience with large breed dogs and has the physical strength to manage a Mastiff Older kids or teenagers only (age 12+) Fenced, secure yard A space for Apollo to eat his meals where he feels safe Someone who will keep an eye on the front door when open so he won't run out A Note from Apollo's Current Person "Because I love Apollo and want the best for him, I'm willing to help his new family with costs.  I am happy to contribute toward his care, such as paying for a year of flea/tick and heartworm prevention.  I will also donate $150 to Muddy Paws Second Chance Rescue in connection with his adoption.  This decision is incredibly hard for me, but with his size and young children, it's the best decision for Apollo.  My only goal is to find Apollo a wonderful, stable, forever home with people who can love him the way I do and give him the life he deserves."   The suggested adoption donation for Apollo is $375, which includes a lifetime of free relationship-based training for any behavioral problems (not obedience training).  Muddy Paws is a 501c3 non-profit organization meaning that part of your donation MAY be TAX DEDUCTIBLE. We are a 100% volunteer rescue committed to giving animals a second chance at life. All donations go toward that mission. Adoption fees are the primary source of funding for the cost of veterinary care for our animals. In 2022 alone, we provided animal Healthcare totaling over $399,000 covered mainly through adoption fees. Please Note:  A Courtesy Post designates that an animal is still in the home of its owner and not in a Muddy Paws foster. This means that our exposure to the animal is limited since we are only assisting the owner in finding a new home for their pet. From time to time, owners find a new furever home for their pets outside of Muddy Paws Second Chance Rescue and there is a delay in removing them from our site. We apologize if the Courtesy Post you apply to adopt is unavailable for adoption. Adoptions for Apollo are limited to the area within 50 miles of Omaha so that he can continue to take advantage of free training from our certified positive reinforcement trainers.       Information about the adoption process:  All adoptions require a completed ADOPTION APPLICATION. Once your application has completed our prescreen steps, we will put you in touch with the animal’s foster to see if you and the pet are a good match. If so, we will arrange a meeting for you and the animal. The adoptions for all of our animals will take place in the Omaha, NE area and must be done by the adoptive family in person. We do not ship or deliver. Please Note:  We are a RESCUE, which is different from a shelter. We conduct veterinary and personal reference checks, and a Home Visit (Virtual in some cases) during the application approval process. We always select the right applicant for each animal, based on the animal’s needs. If you and the animal are not a good match, we will help you select another animal, or we will keep your approved application on file for 6 months. To learn about Muddy Paws Second Chance Rescue or donate to our animals, please visit our website at MuddyPawsSecondChanceRescue.com or our Facebook Page Muddy Paws Second Chance Rescue Inc. ##2786562##

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Iowa.

Mastiff puppies and dogs in Iowa cities

Mastiff Puppies near me Mastiff in Adel Mastiff in Algona Mastiff in Altoona Mastiff in Ames Mastiff in Anamosa Mastiff in Ankeny Mastiff in Atlantic Mastiff in Bettendorf Mastiff in Boone Mastiff in Burlington Mastiff in Carroll Mastiff in Cedar Falls Mastiff in Cedar Rapids Mastiff in Centerville Mastiff in Chariton Mastiff in Charles City Mastiff in Cherokee Mastiff in Clarinda Mastiff in Clear Lake Mastiff in Clinton Mastiff in Clive Mastiff in Coralville Mastiff in Council Bluffs Mastiff in Creston Mastiff in Davenport Mastiff in Decorah Mastiff in Denison Mastiff in Des Moines Mastiff in De Witt Mastiff in Dubuque Mastiff in Eldridge Mastiff in Estherville Mastiff in Evansdale Mastiff in Fairfield Mastiff in Fort Dodge Mastiff in Fort Madison Mastiff in Glenwood Mastiff in Grimes Mastiff in Grinnell Mastiff in Harlan Mastiff in Hiawatha Mastiff in Independence Mastiff in Indianola Mastiff in Iowa City Mastiff in Iowa Falls Mastiff in Johnston Mastiff in Keokuk Mastiff in Knoxville Mastiff in Le Mars Mastiff in Manchester Mastiff in Maquoketa Mastiff in Marion Mastiff in Marshalltown Mastiff in Mason City Mastiff in Mount Pleasant Mastiff in Muscatine Mastiff in Nevada Mastiff in Newton Mastiff in North Liberty Mastiff in Norwalk Mastiff in Oelwein Mastiff in Orange City Mastiff in Osceola Mastiff in Oskaloosa Mastiff in Ottumwa Mastiff in Pella Mastiff in Perry Mastiff in Pleasant Hill Mastiff in Red Oak Mastiff in Sheldon Mastiff in Shenandoah Mastiff in Sioux Center Mastiff in Sioux City Mastiff in Spencer Mastiff in Spirit Lake Mastiff in Storm Lake Mastiff in Urbandale Mastiff in Vinton Mastiff in Washington Mastiff in Waterloo Mastiff in Waukee Mastiff in Waverly Mastiff in Webster City Mastiff in West Des Moines Mastiff in Windsor Heights Mastiff in Winterset

Mastiff shelters & rescues in Iowa

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Iowa. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Animal Rescue of Carroll

1721 East 10th Street, Carroll , IA 51401

Pet Types: cats, dogs

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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