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Mastiff puppies and dogs in Iowa

Looking for a Mastiff puppy or dog in Iowa? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Iowa

Below are our newest added Mastiffs available for adoption in Iowa. To see more adoptable Mastiffs in Iowa, use the search tool below to enter specific criteria!
Photo of Ella Mae

Ella Mae

Mastiff

Female, Adult
Cedar Rapids, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
You can fill out an adoption application online on our official website.Meet Ella Mae! Ella is a little shy when she first meets you, but give her just a little time and she'll come right out of her shell! Once she's comfortable, you'll see what a sweet, goofy girl she really is. She loves giving kisses, is very food motivated, and is always happy to make new friends.  Ella Mae is still building her confidence and may startle if someone walks behind her or she steps on something crunchy, but she's making progress everyday. She loves exploring the yard and has even entertained herself with toys. Once she gets comfortable enough to play, she can get some serious zoomies and will happily give you a body slam! Ella has done wonderfully on group walks and greets other dogs nicely through the fence. We think she would thrive with a confident canine companion who can help show her the ropers. She has not yet been cat tested and would do best in a home without any young children as she is still learning all about this big world we live in. Positive reinforcement and a little patience will go a long way with this sweet girl.  She walks beautifully on a leash and hasn't shown any reactivity to things around her. She has also been an absolute rockstar in her kennel. One important note is that Ella Mae is quite the little escape artist and can clear a 5 foot wall with ease! Her future home with need at least a 6 foot privacy fence to keep this athletic girl safely contained.  Ella Mae's adoption fee is $250 and includes her spay, microchip, current vaccinations and preventatives, plus a free basic obedience course with Cedar Run Company in Hiawatha. Last Hope requires that all animals be kept as indoor only pets and that adopters have a history of having kept their pets altered and current on vaccinations and preventative care. Our adoption process includes a background check, home visit, and a vet history check. If you would like to meet Ella Mae, please submit an adoption application on our website, Adopthope.org.Visit this organization's web site to see any additional information available about this pet.August 17, 2026, 4:05 pm
Photo of Freya

Freya

Mastiff

Female, 4 yrs 2 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
Hi, I'm Freya! I'm a sweet mama and came with my 9 puppies. I'm a very good girl. I'm said to have had a few litters in the past and I'm ready to put motherhood behind me and have a little time for myself. Won't you spend it with me? If you're interested in adopting me, please fill out an application at www.polkcountyhumanesociety.org/adopt. You can also reserve an appointment to meet me. Some pets are in foster homes or may already have visits scheduled, so appointments help ensure I’ll be available. Polk County Humane Society is located in Bolivar, Missouri, and we welcome adopters from any state. We have access to a transport to Aurora, CO. Other out of state adopters either travel to Missouri or arrange & pay for air transport. Virtual meet and greets are available on the appointment request. ##2755149##
Photo of Sandy

Sandy

Mastiff/American Pit Bull Terrier

Female, Young
Sioux City, IA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs,
Story
Sandy is good with other dogs and is crate trained, and with slow, supervised introductions, she can get to know kids and cats at her own pace. She's a smart, eager-to-learn girl who is gaining confidence and does best with patience, consistency, and a little encouragement. When it's time to play, Sandy likes to go all in-chasing, pouncing, wrestling, and keeping her friends on their toes! She's ready for a loving home where she can play hard, snuggle up, and make a lifetime of happy memories. $135.00 Fee includes initial vaccines, worming, microchip with registration, and free vet health exam. This pet has been fed Country Vet Naturals, donated to us by Country Vet. Primary Color: Red Brown Secondary Color: White Weight: 53 Age: 1yrs 0mths 2wks
Photo of Apollo (Courtesy Post)

Apollo (Courtesy Post)

English Mastiff

Male, 4 yrs 1 mo
Council Bluffs, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
House-trained,
Story
Gentle Giant English Mastiff, 4 years old - sweet and cuddly.  Seeking adult/teen home with a strong owner who can handle his size and love him as much as his current family. Meet Apollo, a purebred English Mastiff looking for his forever home.  He is a very sweet, gentle-hearted boy who truly loves his people, but his size and clumsineess make him a poor fit for a home with small children.  A friendly "hello" from Apollo can easily knock a toddler or younger kid over.  He needs a home with adults or older kids (age 12+). Apollo's Personality and Daily Habits Calm and protective Would prefer not to share his toys or meals Stranger friendly Apollo is a big cuddler and a bit of a homebody.  He is not a high-energy dog: one walk a day is plenty for him.  The rest of the time, he is happiest sitting on your feet while you work or lounging on his bed nearby.  He'll get up occasionally to bop around outside or play with a toy, but he can be a little lazy and sometimes needs a gentle nudge to get moving. TRAINING Apollo has been professionally trained at All Dogs Unleashed and had a refresher course May 28th.  He walks fairly well and has good manners overall.  He is house trained and does not bark much.  Due to his size and strength, he does require a physically strong person to handle him!!!  On rare occasions, he may get excited if he sees a person or another dog and can try to take off.  His future owner needs to be comfortable handling a very strong dog. General Things to Know about APOLLO He is neutered, up-to-date on all vaccinations and has never had any serious health problems. As a giant breed, he does eat a lot and is more expensive to care for than a smaller dog.  His new family should be prepared for the financial commitment  that comes with a large Mastiff.  All of the AKC papers will be provided. THE PERFECT HOME Someone who will love and cherish him Someone with experience with large breed dogs and has the physical strength to manage a Mastiff Older kids or teenagers only (age 12+) Fenced, secure yard A space for Apollo to eat his meals where he feels safe Someone who will keep an eye on the front door when open so he won't run out A Note from Apollo's Current Person "Because I love Apollo and want the best for him, I'm willing to help his new family with costs.  I am happy to contribute toward his care, such as paying for a year of flea/tick and heartworm prevention.  I will also donate $150 to Muddy Paws Second Chance Rescue in connection with his adoption.  This decision is incredibly hard for me, but with his size and young children, it's the best decision for Apollo.  My only goal is to find Apollo a wonderful, stable, forever home with people who can love him the way I do and give him the life he deserves."   The suggested adoption donation for Apollo is $375, which includes a lifetime of free relationship-based training for any behavioral problems (not obedience training).  Muddy Paws is a 501c3 non-profit organization meaning that part of your donation MAY be TAX DEDUCTIBLE. We are a 100% volunteer rescue committed to giving animals a second chance at life. All donations go toward that mission. Adoption fees are the primary source of funding for the cost of veterinary care for our animals. In 2022 alone, we provided animal Healthcare totaling over $399,000 covered mainly through adoption fees. Please Note:  A Courtesy Post designates that an animal is still in the home of its owner and not in a Muddy Paws foster. This means that our exposure to the animal is limited since we are only assisting the owner in finding a new home for their pet. From time to time, owners find a new furever home for their pets outside of Muddy Paws Second Chance Rescue and there is a delay in removing them from our site. We apologize if the Courtesy Post you apply to adopt is unavailable for adoption. Adoptions for Apollo are limited to the area within 50 miles of Omaha so that he can continue to take advantage of free training from our certified positive reinforcement trainers.       Information about the adoption process:  All adoptions require a completed ADOPTION APPLICATION. Once your application has completed our prescreen steps, we will put you in touch with the animal’s foster to see if you and the pet are a good match. If so, we will arrange a meeting for you and the animal. The adoptions for all of our animals will take place in the Omaha, NE area and must be done by the adoptive family in person. We do not ship or deliver. Please Note:  We are a RESCUE, which is different from a shelter. We conduct veterinary and personal reference checks, and a Home Visit (Virtual in some cases) during the application approval process. We always select the right applicant for each animal, based on the animal’s needs. If you and the animal are not a good match, we will help you select another animal, or we will keep your approved application on file for 6 months. To learn about Muddy Paws Second Chance Rescue or donate to our animals, please visit our website at MuddyPawsSecondChanceRescue.com or our Facebook Page Muddy Paws Second Chance Rescue Inc. ##2786562##
Photo of Carver

Carver

Mastiff

Male, 4 yrs 9 mos
Fort Madison, IA
Size
(when grown) -
Details
-
Story
If you have ANY QUESTIONS or are truly interested in adopting any animal from PAW Animal Shelter Please, fillout an adoption application FIRST!   WE are a high intake No Kill Shelter ran by a staff of 4 and do not always have time to answer every question asked by so many. If you are a good fit for the animal you are interested in -we will call to speak with you, If we feel you are not a good fit , we will contact you about other pets that may be a good fit for your home. Many people are losing the opportunity to adopt the animal they want because they fail to put in an application and the pet was adopted before we could answer your email. .If you have applied for an animal in our facility and have not received a response within 7 days, PLEASE call or contact us again. Though we do our best in trying to answer all emails in a timely manner, sometimes things get away from us, get lost or misplaced. It is never our intention to ignore a request about an adoptable animal in our facility. Sandy Brown, Director, PAW Animal Shelter 319-372-2274 ##1849160##
Photo of Kodak

Kodak

Mastiff/Great Dane

Male, 6 yrs 2 mos
Carroll, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Kodak is a gentle, affectionate 6-year-old Mastiff × Great Dane mix with a calm, loving presence and the sweetest giant-dog personality. He enjoys sunshine, relaxed outdoor time, and close company. Kodak is bonded with Scarlet and does best when adopted with his buddy. Personality and behavior • Temperament: Gentle, loyal, affectionate • Energy: Low to moderate — prefers leisurely walks, lounging in the sun, and calm companionship • Social needs: Friendly with people; enjoys being near his family and benefits from steady, patient handling • Bonded pair: Closely bonded to Scarlet; happiest when adopted together Ideal home • A home that can accommodate a large, calm dog with space to stretch out • Someone who enjoys relaxed outdoor time and can include Kodak in family life rather than leaving him alone for long periods • Best adopted together with Scarlet so both dogs keep their bond and confidence Care notes • Gentle, consistent handling and positive reinforcement work best • Regular low-impact exercise (walks, shaded yard time) and comfortable resting space are important

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Iowa.

Mastiff puppies and dogs in Iowa cities

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Mastiff shelters & rescues in Iowa

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Iowa. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Polk County Humane Society (in Missouri) - Iowa Transport

11101 University Ave Ste B, Clive , IA 50325

Pet Types: cats, dogs

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Rescue

Last Hope Animal Rescue

1825 16th Ave SW, Cedar Rapids , IA 52404

Pet Types: cats, dogs

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Rescue

Animal Rescue of Carroll

1721 East 10th Street, Carroll , IA 51401

Pet Types: cats, dogs

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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