Great Dane Adoption in Iowa: Great Dane Puppies for Sale in Iowa

Adopt a Great Dane near you in Iowa

Below are our newest added Great Danes available for adoption in Iowa. To see more adoptable Great Danes in Iowa, use the search tool below to enter specific criteria!

Loki

Great Dane

Male, Young

Des Moines, IA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Not good with kids, Good with dogs, Not good with cats, House-trained,

Story

Loki is a 3.5 year old Great Dane. Loki loves to snuggle and is very treat motivated. He listens very well but sometimes gets a little excited over the anticipation of a treat. He LOVES to play with toys but has a tendency to eat them. I’ve had the best luck with Kong style toys and, surprisingly, a horse ball! We have had two close calls with swallowed toys so he should still be monitored with them! Loki has a Great Dane “brother” who he plays great with but he has little experience with other dogs. He definitely does not know his size. He’s energetic and loves to run! I am looking to rehome Loki, as well as his “brother”, through no fault of these wonderful boys. My career has led to 12+ hour shifts and soon I will be back in school. I simply can no longer provide them with what they deserve. Though I would love to rehome them together I understand that it is more than a handful to have two Great Danes. If interested in his brother “Odin” please let me know or look for his posting.

Learn More

Bruno

Great Dane

Male, Adult

Muscatine, IA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Not good with dogs, Needs experienced adopter,

Story

I adopted this 12-mth old purebred Dane one week ago on 3/21/26. I was told he did well with cats and other dogs; he does not. I was told he walked well on a leash; he does not. In fact, he appears to have had little to no training during his formative months. He is sweet, adorable, lovable, energetic, happy, and playful. He is also 140 lbs, immensely powerful, plays rough and plays for keeps. Everything is a game to him, every object a chew toy. This beautiful Dane requires a strong, experienced owner familiar with this breed; a large, fenced yard would be a plus, as he yearns to stretch his legs at full speed. He is not protective of his own food, nor is he mean or aggressive toward humans. He is great with kids & adults, but tends to go after other dogs. He could be a great pet with lots of patience and guidance. Not yet neutered. $450 adoption fee includes all necessary vaccines, rabies, and veterinary health check performed on 3/26/26.

Learn More

Eve

Great Dane/Pointer

Female, 7 yrs 3 mos

Monticello, IA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with cats,

Story

Eve is a 7-year-old Great Dane/Pointer mix whose life changed in the blink of an eye. For years, she lived in a nursing home where she brightened the days of residents and staff alike, offering quiet companionship and comfort to everyone she met. When the facility changed ownership, Eve was suddenly no longer allowed to stay. Thankfully, a kind employee stepped in and brought her home so she wouldn’t be left without a place to go. But due to housing restrictions, they weren’t able to keep her permanently. And so, through no fault of her own, Eve has found herself searching for a new place to call home. Because her world was turned upside down so suddenly, Eve can seem a little aloof or subdued when she first meets new people. She just needs a little time to decide that it’s safe to trust again. Once she does, though, her personality begins to shine. She becomes more expressive, joyful, and affectionate with the people she loves. The fastest way to Eve’s heart is definitely through food—she does the absolute cutest little tippy-taps when she knows a treat is coming! Eve is happiest in a cozy, quiet environment, where she can relax and feel secure. Her favorite place is curled up at her person’s feet, soaking up gentle pets. She’s a big fan of belly rubs and head scratches, and once she’s comfortable, she’ll happily lean in for more. She does well with other dogs and is mostly indifferent to them, content to coexist peacefully as long as her boundaries are respected. Eve also does well with cats and older kids who understand how to give her space and be gentle. Eve is fully potty-trained and crate-trained, and she has lovely house manners (she even knows basic commands). After everything she’s been through, Eve isn’t asking for much—just a quiet, loving home where she can spend her days feeling safe, cherished, and certain that she truly belongs. If you have a soft spot for sweet senior dogs and a peaceful home to share, Eve would love nothing more than to curl up at your feet and be your loyal companion for the rest of her days.

Learn More

Summer

Great Dane

Female, Senior

Davenport, IA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

Summer is a 9 year old great dane. She's 119 pounds. I believe she would do great with a family with older children. She gets a little grumpy around little children. My family has had summer since she was able to leave her mom. Summer would love a huge yard to run in and play. She knows basic commands. She's a great lovable dog and I hate to do this but I have 4 young grandchildren living with me and Summer can't handle the littles running around.

Learn More

Estelle

Great Dane/Terrier (Unknown Type, Medium)

Female, 2 yrs 3 mos

Fort Madison, IA

Size

(when grown) -

Details

Story

If you have ANY QUESTIONS or are truly interested in adopting any animal from PAW Animal Shelter Please, fillout an adoption application FIRST! WE are a high intake No Kill Shelter ran by a staff of 4 and do not always have time to answer every question asked by so many. If you are a good fit for the animal you are interested in -we will call to speak with you, If we feel you are not a good fit , we will contact you about other pets that may be a good fit for your home. Many people are losing the opportunity to adopt the animal they want because they fail to put in an application and the pet was adopted before we could answer your email. .If you have applied for an animal in our facility and have not received a response within 7 days, PLEASE call or contact us again. Though we do our best in trying to answer all emails in a timely manner, sometimes things get away from us, get lost or misplaced. It is never our intention to ignore a request about an adoptable animal in our facility. Sandy Brown, Director, PAW Animal Shelter 319-372-2274 ##2119679##

Learn More

Misty Rain AK

Great Dane/Labrador Retriever

Female, 3 yrs 2 mos

Clive, IA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Not good with cats,

Story

Meet Misty! She's a smart lady who is smart as a whip! She's crate trained, mastered many commands (sit, down, off, mat, enough, go to your room, here, all done- more than most kids :). She loves to run, play fetch and be wherever you are! She's a year and a half old, and was lucky enough to have professional training donated to help her find her forever home. Whoever adopts her will receive at least one free hand off session from her trainer to help her transition go perfectly! Her ideal family would be somewhat active (she needs to run around a yard at least a few times per day). She gets along well with other dogs, but calmer dogs are best. Misty loves to play, but she can get very excited if the other dog is too energetic! She would do well with older children. Younger children and cats would require a lot of supervision. Her trainer thinks she would be a great agility dog, but she is smart enough to do anything you want to train her to do! She will require some active parenting to teach her the rules of your house, because she is so smart, she may try to make her own activities if nothing fun is provided! She's potty trained now (we had some overnight accidents until she started going in her crate at night). She's a great dog with a good head on her shoulders, and she wants to know if you are the one for her! $200 In State Adoption Fee (in Texas) $400 Out of State Fee (includes Transportation to your area) $50 Temporary fuel surcharge.

Learn More

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Iowa.

Great Dane puppies and dogs in Iowa

Jump to:

Adopt a Great Dane near you in Iowa

Below are our newest added Great Danes available for adoption in Iowa. To see more adoptable Great Danes in Iowa, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Iowa cities

Great Dane shelters & rescues in Iowa

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics

Home

Adopt a Dog

Adopt a Great Dane

Iowa

Great Dane puppies and dogs in Iowa

Jump to:

Adopt a Great Dane near you in Iowa

Below are our newest added Great Danes available for adoption in Iowa. To see more adoptable Great Danes in Iowa, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Iowa cities

Great Dane shelters & rescues in Iowa

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics