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Great Dane puppies and dogs in Saint Clair, Missouri

Looking for a Great Dane puppy or dog in Saint Clair, Missouri? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Saint Clair, Missouri Other pups in Saint Clair, Missouri Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Saint Clair, Missouri Great Dane shelters and rescues in Saint Clair, Missouri Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Saint Clair, Missouri

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Saint Clair, Missouri

These Great Danes are available for adoption close to Saint Clair, Missouri.
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Yogi

Great Dane Mixed Breed (Large)

Male, 1 yr 4 mos
Pacific, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Meet Yogi 🐾 Yogi is a 1-year-old high energy boy with the biggest heart 🤎 He loves attention, playing, and being close to his people at all times. He does great with bigger kids and would thrive with an active family who can match his energy and give him lots of love. He can get a little anxious when away from his people because he bonds deeply and always wants to be part of the action. Yogi also has no idea how big he is, so expect lots of oversized cuddles, leaning on you, and goofy moments 😂 He’s still young, playful, and learning, but he’s incredibly loving and loyal. Yogi is looking for a forever home filled with patience, affection, and plenty of belly rubs and he’ll love his people with his whole heart in return.

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Scooby

Great Dane

Male
Fenton, MO
Size
(when grown) -
Details
Spayed or Neutered,
Story
Meet Scooby. This sweet boy is an 8-month-old Great Dane weighing a whopping 107lbs. Total velcro love bug. What we know: ✅ Lived with dogs ✅ Lived with older considerate kids (young toddlers make him nervous ✅ Was dog-sat with cats and did well ✅ Young, sweet, and deserving of a chance He’s just a baby in a giant body. Apply online to adopt him.  Www.4paws4rescueJune 17, 2026, 6:52 pm

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Foster Homes Needed

Great Dane

Male, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats,
Story
Please consider fostering a Great Dane. It will be the best decision you ever made. Please visit www.foreverfriendsgdri.com Thank you

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Winnie

Great Dane

Female, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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Violet

Great Dane

Female, Adult
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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Special Needs
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Goose

Great Dane

Male, Adult
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs special attention, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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These pups are in Saint Clair, Missouri too!

Below are our newest added Great Danes available for adoption in Saint Clair, Missouri. To see more adoptable Great Danes in Saint Clair, Missouri, use the search tool below to enter specific criteria!
Photo of Ranger

Ranger

Anatolian Shepherd Great Pyrenees

Male, 2 yrs 1 mo
St Clair, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Ranger was initially rescued by a Good Samaritan in 2024. He was found in the middle of a road just hours old with his umbilical cord still attached! A nursing mother was found for him & after he was old enough to eat gruel, Ranger came into rescue. Ranger was adopted as a puppy by his foster family but in December 2025, his family could no longer keep him so Ranger came back to us. Fun loving Ranger needs a forever home! 2 year old Ranger is a really sweet boy that loves to play. He enjoys the out of doors and will let you know what he sees and hears with his bark! Ranger likes his chill time too and will sleep in bed with you or in his crate. Ranger does well meeting new people, men and women alike and loves to play with other dogs— likes balls & playing fetch, especially with another dog playing too. And rather then shredding toys, he cobbs them like an ear of corn. Oh Ranger you silly boy! Ranger does well with car rides— he sits on his rear like a gentleman. He knows how to sit, shake and lay down. He does pull on a leash some but is getting better. And leave your counters clear or Ranger will swipe any yummies left behind! We have not done Ranger’s DNA, however we think he’s an Anatolian Shepherd mix with maybe some Great Pyrenees. He had the Pyrenees fluffy white undercoat as a puppy. A great eater, Ranger has the lean Shepherd physique and weighs 60-65 lbs. Ranger is neutered, up to date on vaccines, microchipped, and heartworm negative. Ranger is being fostered in Little Rock, AR Adoption Requirements *A secure, visible fence *A home visit *Children in the home should be 12+ *A vet reference with at least a two year vet history Adopters can be located in Missouri, Illinois, Iowa, Kansas, Nebraska, and Arkansas. We are able to help transport to those states.

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Saint Clair, Missouri.

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Great Dane puppies and dogs in nearby cities

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Related breeds in Saint Clair, Missouri

Anatolian Shepherds in Saint Clair, Missouri Bullmastiffs in Saint Clair, Missouri Irish Wolfhounds in Saint Clair, Missouri

Great Dane shelters & rescues in Saint Clair, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Saint Clair, Missouri. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

15.6 miles

Home 2 Home Canine Orphanage

Pacific, MO 63069

Pet Types: dogs

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Rescue

30.3 miles

4 Paws 4 Rescue

Fenton, MO 63026

Pet Types: cats, dogs, rabbits, small animals

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Rescue

31.7 miles

Forever Friends Great Dane Rescue - Missouri

St. Louis, MO 63017

Pet Types: dogs

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Shelter

36.2 miles

St Charles County Humane Services

4850 Mid Rivers Mall Dr, St. Peters, MO 63376

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

37.4 miles

Gods Dogs Rescue of TX for St Louis Transport Stop

St Louis, MO 63146

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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