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Great Dane puppies and dogs in Saint Clair, Missouri

Looking for a Great Dane puppy or dog in Saint Clair, Missouri? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Saint Clair, Missouri Other pups in Saint Clair, Missouri Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Saint Clair, Missouri Great Dane shelters and rescues in Saint Clair, Missouri Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Saint Clair, Missouri

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Or, how about these Great Danes in cities near Saint Clair, Missouri

These Great Danes are available for adoption close to Saint Clair, Missouri.
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Yogi

Great Dane Mixed Breed (Large)

Male, 1 yr 6 mos
Pacific, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Meet Yogi 🐾 Yogi is a 1-year-old high energy boy with the biggest heart 🤎 He loves attention, playing, and being close to his people at all times. He does great with bigger kids and would thrive with an active family who can match his energy and give him lots of love. He can get a little anxious when away from his people because he bonds deeply and always wants to be part of the action. Yogi also has no idea how big he is, so expect lots of oversized cuddles, leaning on you, and goofy moments 😂 He’s still young, playful, and learning, but he’s incredibly loving and loyal. Yogi is looking for a forever home filled with patience, affection, and plenty of belly rubs and he’ll love his people with his whole heart in return.

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Violet

Great Dane

Female, Adult
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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MIKE

Great Dane

Male, 7 mos
St. Louis, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Meet Mike! This handsome eight-month-old pup has long legs, a big smile and plenty of growing left to do. As a Great Dane mix, Mike is already 42 pounds—and chances are there will be a whole lot more Mike to love as he grows up!Still very much a puppy, Mike is at a wonderful age for a family ready to help him learn, explore and become the great dog he`s meant to be. Walks, playtime, training and new adventures are all waiting for him, along with the most important thing of all: a family of his own.Mike has been waiting at the Humane Society of Missouri`s St. Louis City shelter since July 15. He`s ready to stretch those long legs somewhere other than the shelter and start making memories with his new people.Come meet Mike. Your next best friend might just be a big one.

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Zoe

Great Dane

Female, Senior
Saint Charles, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Not good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
We have shared our home with Zoe for 7 years. She is very well behaved and well trained. She aims to please, but needs a firm and loving owner. She is so calm and sweet and wants to be around people. She has some anxiety as most Danes do and takes a little longer to warm up to larger men, but given some time (10 - 30 min) she is just fine. She is not violent, but gets nervous around them. Zoe would benefit from a family that does not have an environment of raised voices. She loves children! She has trouble making new dog friends as she is scared of most dogs, however with patience and training the right person could make it work. She is not a great candidate for doggy daycare or dog parks though. She comes with EVERYTHING she needs, including dog beds, food, and her kennel (5' x 4') which makes her feel safe. She is 3ft tall and @ 140 lbs. I hate to give her up, but I am moving out of the country and cannot take her with me. 😢 I'm praying for the perfect family for her.

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Dante JuM

Pointer Great Dane

Male, 4 yrs 9 mos
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Meet Dante, the charismatic Great Dane/pointer mix with a captivating blend of rough-around-the-edges charm and a tender heart. Dante's exterior may give off an air of confidence, but deep within lies a soft and gentle soul. Just like the characteristics of his heritage, Dante is intelligent and alert, always ready to engage with the world around him. He possesses a unique blend of confidence and independence, which adds to his intriguing personality. While he may be a bit standoffish at first due to his exceptional intelligence and focused nature, once Dante warms up to you, he becomes a tail-wagging, people-loving companion who will shower you with affection. It is crucial for Dante to be socialized thoroughly, gradually introducing him to a wide variety of people and animals in a gentle and patient manner. By providing Dante with the love, patience, and guidance he needs, you have the opportunity to witness his transformation into a devoted and loyal companion. Adopt Dante today and unlock the layers of his beautiful character, as he fills your life with joy, companionship, and a unique kind of elegance that only he can provide. Local adoption fee is $300(in TX) Out of state adoption fee is $550 (includes transport to your area)

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Photo of OLIVIA

OLIVIA

German Shepherd Dog Great Dane

Female, 5 yrs 2 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
This beautiful girl is Olivia! She is calm, friendly and happy and enjoys her outdoor time. She loves car rides as well as cuddle time. She walks nicely on a leash, is quiet around other dogs and prefers to potty outside. Come meet this lovely girl today!

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These pups are in Saint Clair, Missouri too!

Below are our newest added Great Danes available for adoption in Saint Clair, Missouri. To see more adoptable Great Danes in Saint Clair, Missouri, use the search tool below to enter specific criteria!
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Ranger

Anatolian Shepherd Great Pyrenees

Male, 2 yrs 3 mos
St Clair, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Ranger was initially rescued by a Good Samaritan in 2024. He was found in the middle of a road just hours old with his umbilical cord still attached! A nursing mother was found for him & after he was old enough to eat gruel, Ranger came into rescue. Ranger was adopted as a puppy by his foster family but in December 2025, his family could no longer keep him so Ranger came back to us. Fun loving Ranger needs a forever home! 2 year old Ranger is a really sweet boy that loves to play. He enjoys the out of doors and will let you know what he sees and hears with his bark! Ranger likes his chill time too and will sleep in bed with you or in his crate. Ranger does well meeting new people, men and women alike and loves to play with other dogs— likes balls & playing fetch, especially with another dog playing too. And rather then shredding toys, he cobbs them like an ear of corn. Oh Ranger you silly boy! Ranger does well with car rides— he sits on his rear like a gentleman. He knows how to sit, shake and lay down. He does pull on a leash some but is getting better. And leave your counters clear or Ranger will swipe any yummies left behind! We have not done Ranger’s DNA, however we think he’s an Anatolian Shepherd mix with maybe some Great Pyrenees. He had the Pyrenees fluffy white undercoat as a puppy. A great eater, Ranger has the lean Shepherd physique and weighs 60-65 lbs. Ranger is neutered, up to date on vaccines, microchipped, and heartworm negative. Ranger is being fostered in Little Rock, AR Adoption Requirements *A secure, visible fence *A home visit *Children in the home should be 12+ *A vet reference with at least a two year vet history Adopters can be located in Missouri, Illinois, Iowa, Kansas, Nebraska, and Arkansas. We are able to help transport to those states.

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Saint Clair, Missouri.

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Great Dane puppies and dogs in nearby cities

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Related breeds in Saint Clair, Missouri

Anatolian Shepherds in Saint Clair, Missouri Bullmastiffs in Saint Clair, Missouri Irish Wolfhounds in Saint Clair, Missouri

Great Dane shelters & rescues in Saint Clair, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Saint Clair, Missouri. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

15.6 miles

Home 2 Home Canine Orphanage

Pacific, MO 63069

Pet Types: dogs

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Rescue

31.7 miles

Forever Friends Great Dane Rescue - Missouri

St. Louis, MO 63017

Pet Types: dogs

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Shelter

43.4 miles

Humane Society of Missouri

1201 Macklind Av, St. Louis, MO 63110

Pet Types: cats, birds, dogs, rabbits, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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