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Great Dane puppies and dogs in Saint Clair, Missouri

Looking for a Great Dane puppy or dog in Saint Clair, Missouri? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Saint Clair, Missouri Other pups in Saint Clair, Missouri Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Saint Clair, Missouri Great Dane shelters and rescues in Saint Clair, Missouri Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Saint Clair, Missouri

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Saint Clair, Missouri

These Great Danes are available for adoption close to Saint Clair, Missouri.
We'll also keep you updated on Holyfield's adoption status with email updates.
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Holyfield

Great Dane Rottweiler

Male, Young
Ballwin, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Holyfield (After Evander Holyfield, a portion of his right ear was bitten off during his first weeks of life) is a very affectionate dog that loves attention. He was given back to me from his previous owner due to a medical condition of his owner's mother in-law. He has all of his shots up to date but has not been neutered yet. A home with a fenced back yard or a farm is a must (No apartments) and he has been eating Purina one large breed puppy chow for that last 3 weeks. I have his 3 siblings and the mother who is a Rottweiler. He'll be 1 year old on May 30th. I look forward to getting the right person/family their new best friend.

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We'll also keep you updated on Foster Homes Needed's adoption status with email updates.
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Foster Homes Needed

Great Dane

Male, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats,
Story
Please consider fostering a Great Dane. It will be the best decision you ever made. Please visit www.foreverfriendsgdri.com Thank you

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We'll also keep you updated on Mollie's adoption status with email updates.
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Mollie

Great Dane

Female, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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We'll also keep you updated on Humphries's adoption status with email updates.
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Humphries

Great Dane

Male, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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We'll also keep you updated on Violet's adoption status with email updates.
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Violet

Great Dane

Female, Adult
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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We'll also keep you updated on Milo's adoption status with email updates.
Photo of Milo

Milo

Great Dane

Male, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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These pups are in Saint Clair, Missouri too!

Below are our newest added Great Danes available for adoption in Saint Clair, Missouri. To see more adoptable Great Danes in Saint Clair, Missouri, use the search tool below to enter specific criteria!
We'll also keep you updated on Ranger's adoption status with email updates.
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Ranger

Anatolian Shepherd Great Pyrenees

Male, 1 yr 11 mos
St Clair, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Ranger was initially rescued by a Good Samaritan in 2024. He was found in the middle of a road just hours old with his umbilical cord still attached! A nursing mother was found for him & after he was old enough to eat gruel, Ranger came into rescue. Ranger was adopted as a puppy by his foster family but in December 2025, his family could no longer keep him so Ranger came back to us. Fun loving Ranger needs a forever home! 2 year old Ranger is a really sweet boy that loves to play. He enjoys the out of doors and will let you know what he sees and hears with his bark! Ranger likes his chill time too and will sleep in bed with you or in his crate. Ranger does well meeting new people, men and women alike and loves to play with other dogs— likes balls & playing fetch, especially with another dog playing too. And rather then shredding toys, he cobbs them like an ear of corn. Oh Ranger you silly boy! Ranger does well with car rides— he sits on his rear like a gentleman. He knows how to sit, shake and lay down. He does pull on a leash some but is getting better. And leave your counters clear or Ranger will swipe any yummies left behind! We have not done Ranger’s DNA, however we think he’s an Anatolian Shepherd mix with maybe some Great Pyrenees. He had the Pyrenees fluffy white undercoat as a puppy. A great eater, Ranger has the lean Shepherd physique and weighs 60-65 lbs. Ranger is neutered, up to date on vaccines, microchipped, and heartworm negative. Ranger is being fostered in Little Rock, AR Adoption Requirements *A secure, visible fence *A home visit *Children in the home should be 12+ *A vet reference with at least a two year vet history Adopters can be located in Missouri, Illinois, Iowa, Kansas, Nebraska, and Arkansas. We are able to help transport to those states.

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Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Saint Clair, Missouri.

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Great Dane puppies and dogs in nearby cities

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Related breeds in Saint Clair, Missouri

Anatolian Shepherds in Saint Clair, Missouri Bullmastiffs in Saint Clair, Missouri Irish Wolfhounds in Saint Clair, Missouri

Great Dane shelters & rescues in Saint Clair, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Saint Clair, Missouri. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

31.7 miles

Forever Friends Great Dane Rescue - Missouri

St. Louis, MO 63017

Pet Types: dogs

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Shelter

33 miles

No Time to Spare Animal Rescue and Sanctuary

27933 Pendleton Lost Creek Rd, Warrenton, MO 63383

Pet Types: dogs, farm animals, horses

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Shelter

37.4 miles

Humane Society of Missouri - Maryland Heights

11660 Administration Dr., (Page Ave. and Schuetz Road), Maryland Heights, MO 63146

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

37.4 miles

Gods Dogs Rescue of TX for St Louis Transport Stop

St Louis, MO 63146

Pet Types: dogs

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Shelter

42 miles

Phelps County Animal Rescue

745 E Springfield, Saint James, MO 65559

Pet Types: cats, dogs

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Shelter

42.3 miles

Helping Strays of Monroe County

4221 Hanover Rd., Columbia, IL 62236

Pet Types: cats, dogs

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Shelter

44.5 miles

City of St. Charles Animal Shelter

2835 W. Randolph St, Saint Charles, MO 63301

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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