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Great Dane puppies and dogs in Saint Clair, Missouri

Looking for a Great Dane puppy or dog in Saint Clair, Missouri? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Saint Clair, Missouri Other pups in Saint Clair, Missouri Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Saint Clair, Missouri Great Dane shelters and rescues in Saint Clair, Missouri Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Saint Clair, Missouri

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Saint Clair, Missouri

These Great Danes are available for adoption close to Saint Clair, Missouri.
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Yogi

Great Dane Mixed Breed (Large)

Male, 1 yr 7 mos
Pacific, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Meet Yogi 🐾 Yogi is a 1-year-old high energy boy with the biggest heart 🤎 He loves attention, playing, and being close to his people at all times. He does great with bigger kids and would thrive with an active family who can match his energy and give him lots of love. He can get a little anxious when away from his people because he bonds deeply and always wants to be part of the action. Yogi also has no idea how big he is, so expect lots of oversized cuddles, leaning on you, and goofy moments 😂 He’s still young, playful, and learning, but he’s incredibly loving and loyal. Yogi is looking for a forever home filled with patience, affection, and plenty of belly rubs and he’ll love his people with his whole heart in return.

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Violet

Great Dane

Female, Adult
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.

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Dante JuM

Pointer Great Dane

Male, 4 yrs 10 mos
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Meet Dante, the charismatic Great Dane/pointer mix with a captivating blend of rough-around-the-edges charm and a tender heart. Dante's exterior may give off an air of confidence, but deep within lies a soft and gentle soul. Just like the characteristics of his heritage, Dante is intelligent and alert, always ready to engage with the world around him. He possesses a unique blend of confidence and independence, which adds to his intriguing personality. While he may be a bit standoffish at first due to his exceptional intelligence and focused nature, once Dante warms up to you, he becomes a tail-wagging, people-loving companion who will shower you with affection. It is crucial for Dante to be socialized thoroughly, gradually introducing him to a wide variety of people and animals in a gentle and patient manner. By providing Dante with the love, patience, and guidance he needs, you have the opportunity to witness his transformation into a devoted and loyal companion. Adopt Dante today and unlock the layers of his beautiful character, as he fills your life with joy, companionship, and a unique kind of elegance that only he can provide. Local adoption fee is $300(in TX) Out of state adoption fee is $550 (includes transport to your area)

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Gunner

Labrador Retriever Great Dane

Male, 10 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! WE ARE A TEXAS BASED RESCUE. THIS DOG IS CURRENTLY IN TEXAS AND WILL BE TRANSPORTED TO YOUR STATE ONCE ADOPTED. Our app can be found at haydudeequine.org Hi there! I'm Gunner. I'm an 10-month-old pup weighing about 60 pounds, and I'm looking for a family who appreciates a dog with a big heart and an even bigger personality. I've been told I'm quite the conversationalist. Now, don't worry—I'm not a nonstop barker. I just like to share my thoughts. If you're talking, I'll probably have something to say about it. If dinner is running late, expect a few comments. If we're headed out on an adventure, you'll definitely hear my excitement. Some people call it sass; I call it excellent communication skills. When I'm not busy chatting, you'll probably find me in the water. I absolutely LOVE to swim, splash, and play. A pond, pool, creek, lake, sprinkler—if it's wet, I'm interested. Water is my happy place, and I'd love a family who enjoys outdoor adventures as much as I do. I'm a sweet, social guy who enjoys making new friends and being part of the action. At 60 pounds, I'm a sturdy pup, but I'm still young and excited to learn new things. Whether we're exploring the great outdoors, going for a walk, or relaxing at home, I'll be right by your side—offering companionship, loyalty, and the occasional opinion. If you're looking for a friendly, water-loving best friend who will keep you laughing and always be ready for the next adventure, I might be the perfect match. Hope to meet you soon! Love, Gunner

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These pups are in Saint Clair, Missouri too!

Below are our newest added Great Danes available for adoption in Saint Clair, Missouri. To see more adoptable Great Danes in Saint Clair, Missouri, use the search tool below to enter specific criteria!
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Ranger

Anatolian Shepherd Labrador Retriever

Male, 2 yrs 4 mos
St Clair, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Are you looking for a fun loving, adventuresome boy who would love to be your companion? Ranger was initially rescued by a Good Samaritan in 2024. He was found in the middle of a road just hours old with his umbilical cord still attached! A nursing mother was found for him & after he was old enough to eat gruel, Ranger came into rescue. Ranger was adopted as a puppy by his foster family but in December 2025, his family could no longer keep him so Ranger came back to us. Fun loving Ranger needs a forever home! 2 year old Ranger is a really sweet boy that loves to play. He does well meeting new people men and women alike. He enjoys going to doggie daycare and loves to play with other dogs there and in his foster home. Ranger loves balls and playing fetch, especially with another dog playing too. And rather than shredding toys, he cobbs them like an ear of corn. Oh Ranger, you silly boy! Ranger enjoys the out of doors and one of his favorite past times is barking at squirrels. Indoors, he will alert you when someone is at the door. Ranger likes his chill time too and will sleep in bed with you or in his crate. Always up for an adventure, Ranger does well with car rides; he sits on his rear like a gentleman. He knows how to sit, shake and lay down. He does pull on a leash some. And leave your counters clear or Ranger will swipe any yummies left behind! We have not done Ranger’s DNA, however we think he’s an Anatolian Shepherd mixed with Great Pyrenees and Labrador. A great eater & loves his treats, Ranger has the lean Anatolian physique and weighs 60-65 lbs. Ranger is neutered, up to date on vaccines, microchipped, and heartworm negative. Ranger is being fostered in Little Rock, AR Adoption Requirements *A secure, visible fence *A home visit *A vet reference with at least a two year vet history Adopters can be located in Missouri, Illinois, Iowa, Kansas, Nebraska, and Arkansas. We are able to help transport to those states.

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Saint Clair, Missouri.

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Great Dane puppies and dogs in nearby cities

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Related breeds in Saint Clair, Missouri

Anatolian Shepherds in Saint Clair, Missouri Bullmastiffs in Saint Clair, Missouri Irish Wolfhounds in Saint Clair, Missouri

Great Dane shelters & rescues in Saint Clair, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Saint Clair, Missouri. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

15.6 miles

Home 2 Home Canine Orphanage

Pacific, MO 63069

Pet Types: dogs

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Rescue

31.7 miles

Forever Friends Great Dane Rescue - Missouri

St. Louis, MO 63017

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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