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Great Dane puppies and dogs in Henderson, North Carolina

Looking for a Great Dane puppy or dog in Henderson, North Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Henderson, North Carolina Other pups in Henderson, North Carolina Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Henderson, North Carolina Great Dane shelters and rescues in Henderson, North Carolina Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Henderson, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Henderson, North Carolina

These Great Danes are available for adoption close to Henderson, North Carolina.
We'll also keep you updated on Quinn's adoption status with email updates.
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Quinn

Great Dane

Male, 1 mo
RALEIGH, NC
Size
(when grown) -
Details
Not good with kids, Not good with dogs, Not good with cats,
Story
Meet Quinn 💙 Great Dane Pup • Gentle Soul • Cleft Palate Warrior Quinn may have been born with a cleft palate—but that doesn’t define him. What does define him? His giant heart, his calm spirit, and the way he melts into your arms like he was born to be loved. He was lovingly surrendered at just 2 days old by a breeder who realized he needed extra care. Because of his cleft palate—where the roof of the mouth didn’t fully close—he couldn’t nurse safely and was tube-fed around the clock in our nursery. Thanks to that early care, Quinn is thriving—and now, he's just a happy, healthy puppy looking for his forever home. 💡 What does his cleft palate mean going forward? Puppies like Quinn can eat completely normally once weaned—as long as they use an elevated food dish to help prevent food or water from sneaking into the nose. No special food, no medication—just a simple adjustment that makes a big difference. Surgery is not required, and many cleft pups live full, happy lives with no ongoing issues. Quinn is everything you could want in a Great Dane—loyal, loving, and ready to be someone’s gentle giant.

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We'll also keep you updated on Quest's adoption status with email updates.
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Quest

Great Dane

Male, 1 mo
RALEIGH, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats,
Story
From the start, Quest has lived up to his name—bold, brave, and ready to take on the world. He came into rescue at just a few days old, lovingly surrendered by a breeder who recognized he needed specialized care. Quest was born with a cleft palate, a condition where the roof of the mouth doesn’t fully close. That meant he couldn’t safely nurse, so he was tube-fed around the clock in our nursery until he was strong enough to grow on his own. Now? He’s thriving. 💡 What does his cleft palate mean long-term? Puppies like Quest typically require just one lifelong adjustment: an elevated food dish to help prevent food or water from going up the nose. No special diet. No medications. No surgery required unless problems develop (which they rarely do). Quest eats and plays just like any other puppy—and has no idea he was ever different. He’s outgoing, affectionate, and a total heart-stealer. Whether he’s cuddling with his humans or tumbling around with his toys, Quest is living proof that cleft palate puppies are just as perfect as any other.

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We'll also keep you updated on Qira's adoption status with email updates.
Photo of Qira

Qira

Great Dane

Female, 1 mo
RALEIGH, NC
Size
(when grown) -
Details
Not good with kids, Not good with dogs, Not good with cats,
Story
Qira is grace wrapped in puppy paws—gentle, soulful, and born to be someone’s heart dog. She came to us at just 2 days old, lovingly surrendered by a breeder who wanted her to have the best chance at life. Qira was born with a cleft palate, meaning the roof of her mouth didn’t fully form. Because of that, she couldn’t safely nurse and needed round-the-clock tube feeding to grow strong and healthy. And now? She’s thriving—and absolutely stunning. 💡 What does her cleft palate mean for adopters? Qira will live a full, normal life with one small adjustment: she’ll need to eat from an elevated food dish to help prevent food or water from going up her nose. That’s it. No special food, no medication, and no surgery required unless complications arise (which is rare). She eats, plays, and lives just like any other puppy. With her calm spirit and gentle eyes, Qira is already winning hearts everywhere she goes. She’s ready to become someone’s beloved companion for life.

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We'll also keep you updated on Aiken CP's adoption status with email updates.
Photo of Aiken CP

Aiken CP

Great Dane Labrador Retriever

Male, Young
Chapel Hill, NC
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats,
Story
Hi! Im Aiken, and Im a 6-month-old male black Lab. Im still getting the hang of this whole world thing, so Im a little on the shy side. I like to take my time to warm up to new people and places, but after a day or two, Im your best friend forever! I love cuddling up with my humans and giving tail wags and kisses. My favorite things to do are bunny hop around chasing my toys, chewing on a nice cooool ice cube, and having a Kong filled with peanut butter! Ive got big, soulful eyes and a soft, silky coat. People also tell me Ive got the best personality and that i am one of a kind! Im not the loudest dog on the block, but Ive got a heart full of love waiting to come out. I am a very gentle and polite young lad so Im good with kids and other dogs and cats! I am crate trained and potty trained. I am leash trained but walks can be overwhelming for me sometimes so I like to go somewhere thats nice and chill. I have been recently neutered so I'm all ready to join your family! I would love to show you how special I am and I promise to steal your heart with my bunny hops and zoomies!!

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Great Dane puppies and dogs in nearby cities

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Great Dane shelters & rescues in Henderson, North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Henderson, North Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

44.9 miles

Beautiful Together Animal Sanctuary

Chapel Hill, NC 27517

Pet Types: cats, dogs

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Rescue

30 miles

Blazin' Trails Bottle Babies, Inc.

RALEIGH, NC 27614

Pet Types: dogs

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Looking for a specific shelter or rescue?

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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