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Great Dane puppies and dogs in Wake Forest, North Carolina

Looking for a Great Dane puppy or dog in Wake Forest, North Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Wake Forest, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Wake Forest, North Carolina

These Great Danes are available for adoption close to Wake Forest, North Carolina.
We'll also keep you updated on Misty (bonded w/ Penny)'s adoption status with email updates.
Photo of Misty (bonded w/ Penny)

Misty (bonded w/ Penny)

Great Dane Mastiff

Female, 3 yrs
Wendell, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Misty! Misty and her sister Penny are looking for their forever home together. These girls are littermates and have spent their whole lives together. House broken, dog friendly, and fully vetted, they're hoping to find a home that loves them both! These gentle giants (and big lap puppies!) Would fit in most homes, but we would advise no small animals or small children due to their size.  ##2649812##
We'll also keep you updated on Penny (bonded w/ Misty!)'s adoption status with email updates.
Photo of Penny (bonded w/ Misty!)

Penny (bonded w/ Misty!)

Great Dane Mastiff

Female, 3 yrs
Wendell, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Penny! Penny and her sister Misty are 3 year old great dane × mastiffs who are looking for their forever home. Their owners surrendered them due to no fault of their own.  Together their entire lives, these girls need to stay together. They are good with other dogs, house broken, and fully vetted. These gentle giants are sweet and need someone to love them! We wouldn't recommend them for small animals, or small children just due to their size.  ##2649811##
We'll also keep you updated on Steve Harrington's adoption status with email updates.
Photo of Steve Harrington

Steve Harrington

Great Dane

Male, 3 mos
Raleigh, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained,
Story
✨ Meet Steve Harrington ✨ Yes, that Steve Harrington, because much like the Stranger Things icon, this guy is impossibly handsome, wildly lovable, and rocking the most perfect floppy ears you’ve ever seen. Steve was found wandering downtown alone about two weeks ago, all skin and bones, trying to figure life out way too young. A friend scooped him up, and he’s been crashing with us ever since. While most rescues are full and the local shelter is closed for repairs (it’s rough out there for a homeless pup), we’re covering his care ourselves until we can find him what he really needs: a forever home. Steve is around 12 weeks old and already 25 pounds, so let’s be clear ... this is not a purse dog. The vet and I both suspect he’s a Great Dane mix, which means he’s on track to be a 100+ lb gentle giant. Big dog people, this is your moment. Despite his size, Steve is pure sunshine. He’s incredibly smart, crate trained, sleeping through the night, and hasn’t had an accident indoors in over a week (honestly, he’s showing off). He loves going for walks, sunbathing in the yard, chewing on sticks like it’s his job, and occasionally unleashing some truly impressive puppy zoomies. He plays beautifully with our two large dogs and can absolutely hold his own. Most importantly: Steve loves people. Like, deeply. Everyone he meets is immediately his best friend, and he’s generous with kisses. Consider yourself warned!
We'll also keep you updated on Enid's adoption status with email updates.
Photo of Enid

Enid

Great Dane

Female, 7 mos
Garner, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
Welcome Wednesday and Enid to the ranch!!!Available for foster or forever now!  GORGEOUS 6 month lab mix puppies Up-to-date and microchipped Good with dogs, cats and kids In Foster with master certified dog trainer Ready to go home now!!!!Statesville, NC  Let's share them everywhere and get them home!!! ##2565560##
We'll also keep you updated on Wednesday's adoption status with email updates.
Photo of Wednesday

Wednesday

Great Dane

Female, 7 mos
Garner, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
Welcome Wednesday and Enid to the ranch!!!Available for foster or forever now!  GORGEOUS 6 month lab mix puppies Up-to-date and microchipped Good with dogs, cats and kids In Foster with master certified dog trainer Ready to go home now!!!!Statesville, NC  Let's share them everywhere and get them home!!! ##2565558##
We'll also keep you updated on Mouse's adoption status with email updates.
Photo of Mouse

Mouse

Great Dane Mixed Breed (Medium)

Female, 4 yrs 1 mo
Durham, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Mouse is a gentle 4-year-old Great Dane. True to her breed, she’s not a high-energy dog—she’s happiest with a nice walk, some thoughtful training time and play, and plenty of cozy moments on the couch. Once she trusts you, she loves to cuddle and will happily wag her little tail with just words of affirmation. Mouse finds confidence through structure and positive reinforcement. She likes playing with other dogs, though—as with many Great Danes—she needs thoughtful boundaries to avoid over-exercising and to support her long-term health. Her ideal home will understand the importance of moderation and ongoing care that helps giant breeds thrive. When Mouse first came into our care, she was very fearful of the world around her. Through patience and consistent support, she’s blossomed into a loving, affectionate companion. She’s still a cautious girl—very gentle, but sensitive—and will need continued, proper socialization to help her flourish. Mouse would do best with adopters who are committed to her long-term physical and emotional well-being. In return, she offers quiet devotion, a loving presence, and the kind of bond that feels incredibly special because you earned it. Mouse is house trained, can walk on leash, knows some basic commands, and is doing well building recall so far. Due to her size, we recommend a home without small children. If you’re looking for a sweet, tender giant who just wants to feel safe and loved, Mouse might be your girl. 💛

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Great Dane shelters & rescues in Wake Forest, North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Wake Forest, North Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

13.9 miles

Carolina Animal Network

Wendell, NC 27591

Pet Types: cats, dogs

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Rescue

19.5 miles

Cause for Paws of NC

Raleigh, NC 27603

Pet Types: cats, dogs

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Rescue

20 miles

Hope Animal Rescue

Durham, NC 27704

Pet Types: dogs

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Rescue

20.4 miles

Rustys Rescue Ranch

267 Timber Dr. #1895, Garner, NC 27529

Pet Types: cats, dogs

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Rescue

30.1 miles

Pawfect Match Rescue and Rehabilitation

Holly Springs, NC 27540

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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