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Great Dane puppies and dogs in Roxboro, North Carolina

Looking for a Great Dane puppy or dog in Roxboro, North Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Roxboro, North Carolina Other pups in Roxboro, North Carolina Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Roxboro, North Carolina Great Dane shelters and rescues in Roxboro, North Carolina Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Roxboro, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Roxboro, North Carolina

These Great Danes are available for adoption close to Roxboro, North Carolina.
We'll also keep you updated on Angel 25-1648's adoption status with email updates.
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Angel 25-1648

Great Dane Mixed Breed (Large)

Female, 6 mos
Yanceyville, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Want to meet Angel? Currently she is in foster care, so call first to make arrangements to visit with her at the Shelter with her foster family during visiting hours. - 12-4 PM Monday, Tuesday, Thursday, Friday - Closed on Wednesday - 10-2 PM Saturday All other times are by appointment only. Please call to make an appointment ~ 336-694-4921. To speed up the adoption process, please fill out an adoption application at: https://new.shelterluv.com/matchme/adopt/APS/Dog If you have not heard back from us in 3 business days, please call the shelter at 336-694-4921. Adoption fees include: Rabies shot, spaying or neutering, 1st round of annual shots and initial deworming. Follow our TikTok page at: https://www.tiktok.com/@apscaswell Facebook @APSCaswell Instagram @caswell_county_aps apscaswell.org

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We'll also keep you updated on Oliver's adoption status with email updates.
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Oliver

Great Dane

Male, Young
Chatham, VA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.Oliver is looking for a home that can keep him safe due to his fragile skin. He will need to wear pajamas/outfits, avoid rough play/sharp or rough surfaces, and must be indoor only (excluding potty walks and monitored outside play in a secure area). His fragile skin causes him to be easily hurt, these small wounds quickly develop into huge gaping sores and require observation, medication and treatment for healing. Many will get infected and he is immune to most every antibiotic but one that he has a low susceptibility to. If he is an only pet then he will require plenty of play and exercise, if you have other pets in the home then you will need to monitor their play in case it gets too rough. He is very friendly and gets along with everyone, he is a big puppy and does like to jump when excited. He is still learning his manners and he loves pets and attention. Will ask to go outside to potty by whining or if you have a bell at the door then he will ring it.Visit this organization's web site to see any additional information available about this pet.November 2, 2025, 12:41 pm

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We'll also keep you updated on Dilly-Dally's adoption status with email updates.
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Dilly-Dally

Great Dane Mixed Breed (Large)

Female, 3 mos
Raleigh, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
Hello world- meet Dilly-dally! We believe she may be a Great Dane/Great Pyrenees mix, so she still has a lot of growing to do and may end up on the larger side. Dilly is the perfect sweet and sassy mix. She loves playing fetch and doing zoomies and then cuddling up next to people on the couch. She will likely continue to be an energetic pup as she grows up, so an active household would be ideal. Dilly-dally is kid- and dog-friendly. She is respectful of other dogs and seems to read their cues well. She would love a home with another playful dog, but could also be a solo pup. She has not been exposed to cats. Dilly is still a puppy and is learning all the puppy skills: housebreaking, leash walking, crate training, and general training/manners. She’s picking things up quickly, but her forever family will need to continue training on all of these skills so that she blossoms into the perfect adult dog.

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We'll also keep you updated on Vodka's adoption status with email updates.
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Vodka

Great Dane Mixed Breed (Large)

Female, 3 mos
Raleigh, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
This adorable little lady is as sweet as she is striking. Vodka is believed to be a Great Dane/Great Pyrenees mix—meaning she’s likely to grow into a big dog with an even bigger heart. While we can’t guarantee her adult size or breed, we can promise she’s packed with potential. Curious, clever, and always ready to explore, Vodka loves spending her days playing in the yard, especially if there’s a ball involved. She enjoys romping with other dogs, learning new things, and soaking up all the sights and sounds of the world around her. When she’s not in “play mode,” this little lady turns into a total snugglebug. She naturally gravitates toward people and is happiest when she can curl up for cuddles or soak in some affection. Vodka will thrive with a family ready for a large, energetic companion and willing to continue her training as she grows. With the right people by her side, she’ll blossom into a devoted, loving best friend. If you’re ready for a big-hearted girl to fill your home with joy, Vodka might be the perfect mix for you!

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Roxboro, North Carolina.

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Great Dane puppies and dogs in nearby cities

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Great Dane shelters & rescues in Roxboro, North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Roxboro, North Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Shelter

19.2 miles

Animal Protection Society of Caswell County

836 County Home Road, Yanceyville, NC 27379

Pet Types: cats, dogs

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Rescue

37.4 miles

SPCA of Pittsylvania County

PO BOX 936, Chatham, VA 24531

Pet Types: cats, dogs

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Rescue

43.9 miles

Freedom Ride Rescue

Raleigh, NC 27604

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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