Great Dane Adoption in North Carolina: Great Dane Puppies for Sale in North Carolina

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

A429222

Great Dane

Male, 8 mos

Fayetteville, NC

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Story

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Kipper

Great Dane/Labrador Retriever

Male, 2 yrs 7 mos

Earl, NC

Size

(when grown) -

Details

Good with kids, Good with dogs, Good with cats,

Story

Meet sweet boy Kipper. Kipper was born August 30, 2023. He, his littermates and his mom ended up at the local county shelter. We pulled him and the rest of his family. Mom is a Great Dane mix, dad or dads were traveling salesmen and did not leave their card for us to find out who they were. Best guess is Dane/Lab mix. Kipper has a unique breathing pattern. Once he is tired, he breathes very heavily. We have taken him to specialists, and they said it is nothing to be alarmed about, just genetic. Kipper is great with other dogs and cats. He also loves, loves, loves his people. He like to snuggle and lean into you to get as close as possible to you. Could Kipper be the match for your new family member?

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Kanga

Great Dane

Female, 4 yrs 4 mos

Earl, NC

Size

(when grown) -

Details

Good with kids, Good with dogs, Good with cats,

Story

Hi! My name is Kanga and I am looking for my human to love, snuggle and cuddle with! I am a Great Dane mix, with the looks of a Dane but a bit smaller. I do love to snuggle and even though I am a pretty big girl, I love to crawl up in your lap! Super sweet with everyone I meet! I walk well on a leash, and will gladly go hiking or walking with you. I do have a good bit of energy so a fenced in yard would be great! We could play fetch and other games together. Did I say I had a good bit of energy and loved to play??? I need a bit more work in the house as I have been known to counter surf. I am crate trained but need more work on my house training. I want to be with you as much as possible. Just look into my beautiful baby blues and you will hopefully fall in love with me as much as I will love you.

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Special Needs

Sven

Great Dane/American Pit Bull Terrier

Male, Adult

North Wilkesboro, NC

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Good with cats, Needs special attention, House-trained,

Story

It breaks my heart to make this post, but my 7-year-old Great Dane/Albino Pit mix is looking for a specific kind of forever home. He is the definition of a "gentle giant"—calm, sweet, and incredibly loyal. Because he has so much love to give, he truly thrives when he’s the "only child." He’s looking for a one-dog household where he can be the center of your world. The Essentials: • Age: 7 years (the perfect mellow adult age!) • Health: Neutered, microchipped, and fully UTD on vaccines. He takes Reconcile and Traazedone for his anxiety. • Ideal Match: Someone with large-breed experience who understands the "velcro dog" nature of Danes and Pits. My priority is his happiness and safety. If you have room in your heart (and on your couch) for a devoted companion, please message me.

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Wednesday

Great Dane

Female, 9 mos

Garner, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Welcome Wednesday and Enid to the ranch!!!Available for foster or forever now! GORGEOUS 6 month lab mix puppies Up-to-date and microchipped Good with dogs, cats and kids In Foster with master certified dog trainer Ready to go home now!!!!Statesville, NC Let's share them everywhere and get them home!!! ##2565558##

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Huckleberry

Great Dane

Male, Puppy

Iron Station, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

Huckleberry I know what you’re thinking. 'This little guy is cute and all, but puppies need a lot of training.' Well guess what? I already know All.The.Things. Okay, maybe not all. Maybe half. Or maybe less than half. I don’t know how many things exactly, because I haven’t learned math yet. But, if you want a puppy who is potty trained, crate trained, knows basic commands, takes cues and redirection, and is past the stabby jaws phase, plus super soft and cuddly - I’m your Huckleberry! And that’s my name! I used to have a home with a fluffy bed and lots of toys, plus a couple of cats. I went to a board and train while I was there and also a doctor who removed my dangly bits. They didn’t have the time for me though, so now I’m in the market for a new home where I can keep learning, keep playing, go for lots of walks, get lots of pets, and have a family who will love me forever and ever. A little about me. I’m a pretty chill dude. My birthday is October 14th, 2025. I’m a Libra. I like car rides, walks, playing fetch, playing with dogs, playing with cats, greeting people, meeting little kids–who are just short people that smell like peanut butter–and napping. I also love learning. In my foster home, I have learned to sit and wait for my food patiently. Okay, not always patiently. Sometimes, I whine a little when it takes too long to get my food ready (why does it take soooo long?) But it’s all good. I know it’s coming and that the other dogs aren’t going to steal it. Do you like to snuggle at night while you’re relaxing? Me too! I love to just chill out after dinner. I also sleep all through the night on my dog bed in the bedroom. That’s how good I am. I wouldn’t mind sleeping in a bed with a human either, but if you’re not okay with that, I don’t judge. I like being outside too. Sometimes, I just hang out in the yard watching the world go by, contemplating the mysteries of life. Like who really is the Best Boy? My foster mom asks me that all the time, and I’m determined to find the answer for her. Because I’m a people pleaser. But not in a toxic way. In a good way. In a ‘I’d like to help you fold the laundry, but I don’t have thumbs’ kind of way. So if all of that sounds good to you, then I’d love to meet you! You can email info@greatdanefriends.com to get an application for me. I’ll need a fenced-in yard to do my world-watching thing. *****Great Dane Friends of Ruff Love covers NC and surrounding states for adoptions. We require a fenced yard (exceptions made on a case by case basis - NO exceptions for puppies or deaf/vision impaired dogs - no invisible fencing), that stairs in the home be covered with some sort of slip resistant material to prevent injury, that all other animals in the home be up to date on vaccinations as well as spayed/neutered and that all dogs live inside as a part of the family. Our approval process consists of an application, vet and reference checks, phone interview and house check. Please email us for an application or if you have any questions.***** April 3, 2026, 2:14 pm

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Great Dane puppies and dogs in North Carolina

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Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

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Great Dane puppies and dogs in North Carolina

Jump to:

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in North Carolina cities

Great Dane shelters & rescues in North Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics