Great Dane Adoption in North Carolina: Great Dane Puppies for Sale in North Carolina

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

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TANK

Great Dane/Great Pyrenees

Male, 3 yrs 1 mo

Clinton, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

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Maui

Great Dane

Male, Young

Camp Lejeune, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

Maui is the sweetest boy ever. Having 5 kids, working and solo parenting. I am just never home. He spends so much time in a kennel it breaks my heart. He deserves to have all the love and attention

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Rue

Great Dane/Mixed Breed (Large)

Female, 2 mos

Asheville, NC

Size

(when grown) -

Details

Story

Rue is one of Lottie's puppies! She's a sweet girl who is bound to grow into a gigantic best buddy! Come meet this puppy this Wednesday from 11 AM to 3 PM at Brother Wolf Animal Rescue! Where: 📍 23 Heritage Drive, Building B, Asheville, NC When: 🗓️ THIS WEDNESDAY from 11 AM to 3 PM We ask that you bring the appropriate gear to bring home the animal you intend to adopt (for cats: carrier; for dogs: carrier or leash and harness/collar) as well as your government-issued ID and a payment method for adoption fees (cash or card, please!). This event is first come first served.

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Briar

Great Dane/Mixed Breed (Large)

Male, 2 mos

Asheville, NC

Size

(when grown) -

Details

Story

Briar is one of Lottie's puppies! He's a sweet boy who is bound to grow into a gigantic best buddy! Come meet this puppy this Wednesday from 11 AM to 3 PM at Brother Wolf Animal Rescue! Where: 📍 23 Heritage Drive, Building B, Asheville, NC When: 🗓️ THIS WEDNESDAY from 11 AM to 3 PM We ask that you bring the appropriate gear to bring home the animal you intend to adopt (for cats: carrier; for dogs: carrier or leash and harness/collar) as well as your government-issued ID and a payment method for adoption fees (cash or card, please!). This event is first come first served.

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Meadow

Great Dane/Mixed Breed (Large)

Female, 2 mos

Asheville, NC

Size

(when grown) -

Details

Story

Meadow is one of Lottie's puppies! She's a sweet girl who is bound to grow into a gigantic best buddy! Come meet this puppy this Wednesday from 11 AM to 3 PM at Brother Wolf Animal Rescue! Where: 📍 23 Heritage Drive, Building B, Asheville, NC When: 🗓️ THIS WEDNESDAY from 11 AM to 3 PM We ask that you bring the appropriate gear to bring home the animal you intend to adopt (for cats: carrier; for dogs: carrier or leash and harness/collar) as well as your government-issued ID and a payment method for adoption fees (cash or card, please!). This event is first come first served.

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Koa

Great Dane

Male, Puppy

Iron Station, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, House-trained,

Story

Meet Koa! This handsome 11-month-old Great Dane is all heart, all legs, and ALL teenage energy. Koa came to us when his college-student owner realized she didn’t have the time to give him the consistency he deserves. With lots of travel and bouncing between Rover stays, family, and friends, Koa hasn’t had much structure in his young life — but he’s soaking it up beautifully in his foster home. Like many adolescent Danes, Koa is in that “bratty teenager” phase. He’s sweet as can be, affectionate, and eager to please — he just needs guidance polishing those manners. The good news? He already knows sit and down, is crate trained, house trained, rides wonderfully in the car, and responds well to direction. He’s smart and ready to learn! Koa gets SUPER excited to see other dogs. He hasn’t had much experience, so his greeting style is best described as… enthusiastic He’s not aggressive in any way — just big, bouncy, and a little over-zealous. If another confident dog tells him “no thank you,” he’s very respectful. But if a dog runs? Well… he thinks it’s playtime! We’re actively working on his social skills and he’s making progress. He also LOVES toys and will happily entertain himself (or you!) with a good play session. After he burns off that puppy energy, he’s a total cuddle bug. &#226&#156&#168 Koa’s perfect home: Active family committed to continuing his training Giant breed experience required A securely fenced yard where he can safely zoom and stretch those long legs Koa is a wonderful young Dane who just needs structure, consistency, and a family ready to guide him into the amazing adult dog he’s going to be. If you’re ready to give this sweet, goofy boy the forever home he deserves, please email info@greatdanefriends.com . Let’s help Koa find his perfect match! *****Great Dane Friends of Ruff Love covers NC and surrounding states for adoptions. We require a fenced yard (exceptions made on a case by case basis - NO exceptions for puppies or deaf/vision impaired dogs - no invisible fencing), that stairs in the home be covered with some sort of slip resistant material to prevent injury, that all other animals in the home be up to date on vaccinations as well as spayed/neutered and that all dogs live inside as a part of the family. Our approval process consists of an application, vet and reference checks, phone interview and house check. Please email us for an application or if you have any questions.***** March 4, 2026, 2:30 pm

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in North Carolina.

Great Dane puppies and dogs in North Carolina

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Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

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Great Dane puppies and dogs in North Carolina cities

Great Dane shelters & rescues in North Carolina

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Great Dane puppies and dogs in North Carolina

Jump to:

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in North Carolina cities

Great Dane shelters & rescues in North Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics