Great Dane Adoption in North Carolina: Great Dane Puppies for Sale in North Carolina

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

Emmory

Great Dane

Female, 2 yrs

Barco, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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Freckles

Great Dane

Female, 2 yrs 2 mos

Winston Salem, NC

Size

(when grown) -

Details

Story

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Dilly-Dally

Great Dane/Mixed Breed (Large)

Female, 3 mos

Raleigh, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs,

Story

Hello world- meet Dilly-dally! We believe she may be a Great Dane/Great Pyrenees mix, so she still has a lot of growing to do and may end up on the larger side. Dilly is the perfect sweet and sassy mix. She loves playing fetch and doing zoomies and then cuddling up next to people on the couch. She will likely continue to be an energetic pup as she grows up, so an active household would be ideal. Dilly-dally is kid- and dog-friendly. She is respectful of other dogs and seems to read their cues well. She would love a home with another playful dog, but could also be a solo pup. She has not been exposed to cats. Dilly is still a puppy and is learning all the puppy skills: housebreaking, leash walking, crate training, and general training/manners. She’s picking things up quickly, but her forever family will need to continue training on all of these skills so that she blossoms into the perfect adult dog.

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Vodka

Great Dane/Mixed Breed (Large)

Female, 3 mos

Raleigh, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs,

Story

This adorable little lady is as sweet as she is striking. Vodka is believed to be a Great Dane/Great Pyrenees mix—meaning she’s likely to grow into a big dog with an even bigger heart. While we can’t guarantee her adult size or breed, we can promise she’s packed with potential. Curious, clever, and always ready to explore, Vodka loves spending her days playing in the yard, especially if there’s a ball involved. She enjoys romping with other dogs, learning new things, and soaking up all the sights and sounds of the world around her. When she’s not in “play mode,” this little lady turns into a total snugglebug. She naturally gravitates toward people and is happiest when she can curl up for cuddles or soak in some affection. Vodka will thrive with a family ready for a large, energetic companion and willing to continue her training as she grows. With the right people by her side, she’ll blossom into a devoted, loving best friend. If you’re ready for a big-hearted girl to fill your home with joy, Vodka might be the perfect mix for you!

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Whiskey

Great Dane

Male, 1 yr

Salisbury, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs,

Story

Meet Whiskey, who comes to us from the Cabarrus County Animal Shelter. Whiskey is a 1-year-old, 45 lb., Great Dane mix. Having arrived at the shelter in an emancipated state, Whiskey is now on the path to regaining a healthy weight. As he fills out, this handsome pup is sure to turn heads. Whiskey is a very loving boy and is diligently working on refining his puppy and leash manners, demonstrating a strong motivation for treats and a desire to learn. With consistent training, we are confident that Whiskey will make rapid progress. Whiskey is neutered, fully vaccinated, and microchipped. If you are interested in fostering or adopting Whiskey, please reach out to us for an application.

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Thor

Great Dane

Male, Young

Albemarle, NC

Size

(when grown) -

Details

Story

Thor and Montana are beautiful Great Danes that were recently surrendered into our care. They have grown up together and have been indoor/outdoor dogs. They like their toys and they like to swim. Call today to schedule a meet and greet. www.stanlycountyhumanesociety.orgAdoption fees for pets with Stanly County Humane Society are to cover the following: *Spay/Neuter *Heartworm/Feline Testing *All standard vaccinations *Rabies Vaccination *Microchip November 18, 2025, 1:20 pm

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Great Dane puppies and dogs in North Carolina

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Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

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Great Dane puppies and dogs in North Carolina

Jump to:

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in North Carolina cities

Great Dane shelters & rescues in North Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics