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Great Dane puppies and dogs in North Carolina

Looking for a Great Dane puppy or dog in North Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!
We'll also keep you updated on Nova's adoption status with email updates.
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Nova

Great Dane/Labrador Retriever

Female, Adult
Fayetteville, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Good with dogs, Good with cats, House-trained,
Story
Loves cats and other dogs, very loving and cuddly, protective of house and home members. The reason she needs rehome is that she has a ton of energy and me and my pregnant wife can’t get her the exercise she needs, because of this she frequently tears things up and has been knocking my wife to the ground for the past few weeks out of excitement and just pure goofiness, which was cute before my wife got pregnant now it’s a huge safety concern for my wife and my child as nova has shown no sign of calming down and I can’t be home constantly to calm her or be her outlet. She is a sweet dog and hasn’t done anything wrong or bad she just doesn’t understand she can’t knock my wife into things and the ground and tear everything up just cause we can’t take her for 2-3 walks everyday anymore. She wasn’t this energy filled when we first got her but now she’s running rampant through the house with playful energy and it is just not a good fit for a pregnant small woman and other small animals.
We'll also keep you updated on Gertie's adoption status with email updates.
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Gertie

Great Dane

Female, Puppy
Iron Station, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained,
Story
✨ Meet Gertrude — “Gertie” to her friends ✨ Gertie is the kind of dog who quietly works her way into your heart and stays there forever. With her stunning orange eyes, gentle soul, and sweet, cautious nature, Gertie is truly a diamond in the rough. Life has not always been kind to her, and while that has made her careful with new people, it has never stopped her from wanting love. She just needs a little time to believe it’s safe. If you move too fast, Gertie will retreat. But if you let her observe you, approach on her own terms, and build trust at her pace, you will discover the most loving, loyal little shadow imaginable. Once you are officially part of Gertie’s circle, prepare for kisses, cuddles, and a constant companion who always wants to know where her people are. And yes — sliced cheese helps tremendously. Gertie is still learning that the world is not such a scary place. Leash walking remains a journey, and sometimes Point A to Point B includes a dramatic pancake flop in protest. But every day she gets a little braver, a little more confident, and a little more willing to trust. Her foster siblings have become her emotional support crew, helping her discover that adventures can actually be fun. She enjoys car rides when her dog friends come too, though stepping out into the “big world” still takes courage. Like any true Dane puppy, Gertie is equal parts gentle giant and tiny velociraptor. She loves with her whole face — literally. She is still learning that affection does not require using her mouth, but every goofy nibble and awkward love chomp comes from pure happiness. At home, Gertie thrives on companionship. She loves wrestling in the yard, evening zoomies, naps near her people, and keeping a close eye on everyone she loves. Very close. If you are searching for independence, Gertie may not be your girl. If you want a Velcro dog who thinks your presence is the greatest thing on earth? Perfect match. She is kennel trained, mostly trustworthy with free roam, and only occasionally believes your socks belong to her now. Gertie needs a patient, understanding home willing to let her bloom in her own time. She does not need perfection. She needs kindness, consistency, and someone who sees the beautiful dog she already is underneath the uncertainty. And for the person willing to give her that chance? You will gain one of the sweetest, softest, most devoted companions imaginable. ❤️ Gertie is being fostered in Fort Mill, SC Email: info@greatdanefriends.com for an application*****Great Dane Friends of Ruff Love covers NC and surrounding states for adoptions. We require a fenced yard (exceptions made on a case by case basis - NO exceptions for puppies or deaf/vision impaired dogs - no invisible fencing), that stairs in the home be covered with some sort of slip resistant material to prevent injury, that all other animals in the home be up to date on vaccinations as well as spayed/neutered and that all dogs live inside as a part of the family. Our approval process consists of an application, vet and reference checks, phone interview and house check. Please email us for an application or if you have any questions.*****   May 12, 2026, 1:19 pm
We'll also keep you updated on Banjo's adoption status with email updates.
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Banjo

Great Dane/Mixed Breed (Large)

Male, 2 yrs 3 mos
FUQUAY VARINA, NC
Size
(when grown) -
Details
-
Story
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We'll also keep you updated on Rogue's adoption status with email updates.
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Rogue

Great Dane

Male, Adult
Gastonia, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained,
Story
Rogue is a 6-year-old Great Dane with a heart as big as he is. He’s a goofy, affectionate gentle giant who thinks he’s a lap dog. He thrives on companionship, physical affection, and spending time outdoors.Rogue does great with other dogs and would love a home with a canine companion. He’s house trained, knows basic commands, and was crate trained earlier in life. He’s not very interested in toys—he’d rather be with his people or another dog.He’s had positive interactions with children, but due to his size and energy, we believe a home without young children would be best.We’re making the difficult decision to rehome him due to our growing family and a now-mobile baby. Rogue is incredibly loving and deserves a home where he’ll get plenty of attention, companionship, and love.
We'll also keep you updated on SCARLETT's adoption status with email updates.
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SCARLETT

Great Dane/American Bulldog

Female, 6 yrs 5 mos
Clyde, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Scarlett is, quite simply, a marshmallow with four legs. A 75-pound, couch-loving, belly-up marshmallow who believes the best things in life are soft places to nap and humans who understand the importance of a good belly rub. If you sit down, she will gently (and strategically) roll onto her back, just in case you needed a reminder of your true purpose.At 6 years old, this Great Dane/Pit Bull mix has perfected the art of being a calm, easygoing companion. She’s mostly a laid-back kind of girl, happy to lounge by your side, but every now and then she surprises you with a little burst of joyful zoomies that will absolutely make your day. Think of her as “mostly chill with a splash of silly.”Scarlett enjoys her walks, appreciates a comfy couch, and would love a home where she can be someone’s loyal, snuggly sidekick. If you’re looking for a big, soft-hearted companion who will happily trade endless love for belly rubs, Scarlett is ready to be your girl.
We'll also keep you updated on Delta's adoption status with email updates.
Photo of Delta

Delta

Great Dane

Female, Adult
Cary, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Special Note about Delta: Delta had a full ophthalmologic workup regarding her mild entropion, which is most noticeable on her lower right eyelid. Her veterinarian confirmed that her eyelashes do not contact the eye or cornea, and surgery is not recommended at this time. She completed a short course of Neopolydex eye medication and does very well with routine lubricating eye drops such as OptixCare lubricating eye gel (or another non-saline eye lubricant), which are recommended for lifelong comfort and eye support. Delta’s condition is currently mild and well managed, and she remains happy and comfortable!   Meet Delta — a 2 year old, 122 lb Great Dane with a giant frame, a giant heart, and a wonderfully pure spirit! Quick Facts: Name: Delta Breed: Great Dane Age: 2 years old Weight: 122 lbs. House-Trained: Yes Crate-Trained: Yes Good with Dogs: Yes (loves to play!) Good with Cats: Yes Good with Kids: Only older, teenage kids due to her size Energy Level: Medium - High Fence Required: Yes   About Delta’s Breed: Our best guess is that Delta is a Great Dane breed. Great Danes are known as gentle giants — affectionate, social, and deeply loyal dogs who love being close to their people. Despite their massive size, they’re typically calm, friendly, and easygoing, with a playful streak that shows up in zoomies and goofy antics. They thrive on companionship and often think they’re lap dogs, leaning in for affection whenever they can. Their ideal home is one with plenty of space, consistent exercise, and lots of human interaction. Because of their size and energy needs, a fenced yard is often important, along with a family familiar with large breed care. Great Danes do best in homes that can offer structure, gentle training, and the time and attention they crave. With the right environment, they become incredibly loving, loyal, and wonderfully charming companions. What to Love about Delta: Delta is social, affectionate, and loves making friends with both dogs and cats. She’s playful and silly, especially when she gets the zoomies in the backyard or when she’s squeaking her favorite toys! And when she’s not playing, she’s a total cuddle bug who loves nothing more than leaning in for affection. Delta is a big fan of car rides — especially when she can stick her head out the window or sunroof to feel the breeze. She’s great on a leash, an easygoing playmate, and has excellent house manners. She’s potty trained, crate trained, and can be trusted loose in the house when you’re away. Her only fear? Vacuum cleaners — they’re her sworn enemy. Her ideal home is one with plenty of affection, attention, and room to run. A fenced yard is a must for her size and energy level. She’d do well as an only dog or with another friendly dog, and she’d thrive with a family familiar with Great Danes or large breed dogs. Delta has medium high energy and needs regular exercise and stimulation to stay happy. She’s wonderful with adults but needs an adult only home or one with older kids, as she’s a large breed dog and may be too big for small children. Delta is an all-around amazing girl — loving, playful, social, and ready to bring joy to her forever family. She can’t wait to find her perfect home and live her best, big dog life! Delta’s Delightful Highlights: • 2 years old, 122 lb Great Dane with a sweet, social, and playful nature • Gets along wonderfully with both dogs and cats • Loves squeaky balls, backyard zoomies, and cuddling with her humans • Absolutely adores car rides, especially with her head out the window or sunroof • Medium high energy and needs plenty of exercise, stimulation, and room to run • Great on a leash, easygoing with other dogs, and an all around fun playmate • Potty trained, crate trained, and has excellent house manners when left alone • Needs an adult only home, or one with teenagers/older kids • Ideal home includes a fenced yard and a family familiar with Great Danes or large breeds • Affectionate, loyal, and ready to find her perfect forever family who will love her big heart and big personality Comprehensive details are provided in the dog's description. to ensure a smooth process, please submit a completed application through our website at: http://crisisdogsnc.org/dog-adoption/. Please note that questions via email or social media channels may not receive a response without a completed application. As part of our commitment to responsible adoption practices, we require excellent veterinarian references and conduct virtual home visits. Additionally, your prior or current dog must be on year-round heartworm prevention. We assist with coordinating transportation by both land and air whenever feasible. All assessments regarding breed and age are conducted by licensed veterinarians. We look forward to assisting you in finding your perfect canine companion!May 13, 2026, 3:57 pm

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in North Carolina.

Great Dane puppies and dogs in North Carolina cities

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Great Dane shelters & rescues in North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in North Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations

Rescue

Great Dane Friends of Ruff Love

Iron Station , NC 28080

Pet Types: dogs

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Rescue

Catering to Cats and Dogs

Charlotte , NC 28215

Pet Types: cats, dogs

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Rescue

Faith Hope and Love Animal Rescue NC

PO Box 4463, Salisbury , NC 28145

Pet Types: dogs

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Rescue

Critter Cavalry Rescue -NC

Charlotte , NC 28201

Pet Types: cats, dogs

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Rescue

Crystal Acres Oasis Sanctuary and Rescue

Gastonia , NC 28056

Pet Types: cats, birds, dogs, farm animals, rabbits, reptiles, small animals

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Rescue

Clifford's Army Rescue Extravaganza

P.O. Box 370, Earl , NC 28038

Pet Types: dogs

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Rescue

Ruff Love Rescue and Foster Care

P. O. Box 2013, Thomasville , NC 27361

Pet Types: cats, dogs

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Rescue

Heart of the Foothills Animal Rescue

380 US HWY 221 N, Rutherfordton , NC 28139

Pet Types: cats, dogs

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Shelter

Rutherford County Animal Control Services

545 Laurel Hill Dr, Rutherfordton , NC 28139

Pet Types: cats, dogs, farm animals, rabbits, small animals

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Want to learn more about adopting a Great Dane puppy or dog ?

We've got all the info you need on adopting and caring for a Great Dane puppy . Check out the links below for everything you ever wanted to know about Great Dane puppies and adults .

Great Dane information

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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