Great Dane Adoption in North Carolina: Great Dane Puppies for Sale in North Carolina

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

Sofie

Great Dane

Female, Adult

Louisburg, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs,

Story

In Dandridge, TN: Hi my name is Sofie - I’m a pretty girl that is sweet and calm. I am 6.5 years old. I’m a pure bred Great Dane - I live with my brother Jax, a 1.5 yr old Great Dane - if you are looking for two pups. My mom unfortunately can’t take care of us anymore but we are good babies looking for a forever home!I know the profile says NC, I have requested for it to be updated - this dog is currently in Danridge, TN.

Learn More

Jax

Great Dane

Male, Adult

Louisburg, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, Good with cats,

Story

In Danridge, TN: Hi! My name is Jax, I’m 1.5 yrs old and I am a loving boy looking for my forever home. I am playful, kind, very handsome and love pets. I have an older sister name Sofie if you are looking for two pups, but we can go to separate homes. I’m still learning not to jump but I’m very smart and respond to treats and training. I’m full bred Great Dane!I know the profile says NC, I have requested for it to be updated - this dog is currently in Danridge, TN.

Learn More

Clifford *

Great Dane

Male, 1 yr 11 mos

Waynesville, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, Good with cats,

Story

Courtesy post. Clifford is not being housed at the shelter. **Located in Candler, NC For more information, call (828) 593-7243 When I rescued him, he was being raised by a drug dealer and in a pretty unstable environment from what I could tell. He knew I rescued him and I've never seen a more appreciative, well behaved dog walk into my life. I named him Clifford because everything about his personality is "Clifford the Big Red Dog" His favorite toy is a jumbo tennis ball. He also loves toys with rope bones in them and plush toys(with no stuffing). He treasures his toys and plays gently with them. He has done great with my smaller dogs....one is a 10 lb male chihuahua mix and the other is an older female dachshund mix. He also gets along well with my female Newfoundland/Lab mix. He is good with our cats as well, but they are very used to dogs and quite tolerant but also good at teaching dogs about cats. Clifford does not do well with other large breed male dogs, which is the primary reason I am having to rehome him.

Learn More

Auggie

Great Dane/Poodle (Standard)

Male, 1 yr

Bryson City, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs,

Story

Learn More

Onyx

Great Dane/Labrador Retriever

Male, Young

Winterville, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, House-trained,

Story

Due to circumstances, I don’t have the yard space to accommodate his size anymore, plus my new landlord does not allow pets. My schedule has also gotten more demanding so the time to spend with him has decreased dramatically. With that, Onyx is a big lovable goofball. He has been with me since he was 6 weeks old and currently a little over 1. His birthday is in May. I have small children and he’s been great with them. He loves to talk (bark) out the window or if he brings you his toy and you don’t see it, he will bark to get your attention. He has been house trained since he was about 2 months old and no accidents since. He goes to the back door to let you know he needs to go out. He’s crate trained as well. If you say “go home” he goes to his crate, especially if you have a bacon treat. He’s great company and just loves to be near.

Learn More

Nala

Great Dane/American Pit Bull Terrier

Female, Young

Holly Springs, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, House-trained,

Story

You can fill out an adoption application online on our official website. Online Adoption Application › Nala | 50lbs | approx 90lbs fully grown | Good with Dogs | Good with Kids Hi I'm Nala, I was originally adopted when I was 2 months old, but sadly, my family couldn't keep me because they didn't have enough time to help me get all my wiggles out. Pawfect match rescued me so now i'm ready for my forever home! Like any puppy, I have a lot of energy that comes in spurts, and then I'm content to nap a couple of hours, preferably as close to you as possible. I would love to be your new lap dog-- I have no idea how big I am or how much bigger I'm going to be when I grow up, thanks to my Great Dane genes. Take a look at my paws. They are bigger than my new buddy Bella's paws who is 80 lbs (Shepherd in pics). Goofball is my middle name. I love to play with my foster family's dogs, and I'm doing my best to convince the little dog that I'm a friendly giant, play bowing as low as I possibly can, and kissing her chin, but until she agrees to play with me, I'm content to run around and play with the bigger dogs. My ideal home will be with someone who can be with me most of the time, and is willing to continue to train me well so I grow up with good manners. Most of all, I'm a huge lovebug and I just want to love you. For more photos: https://www.pawfectmatch.org/animals/detail?AnimalID=22483021 The adoption fee is $400, which covers vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application! Visit this organization's web site to see any additional information available about this pet.August 24, 2026, 11:16 am

Learn More

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in North Carolina.

Great Dane puppies and dogs in North Carolina

Jump to:

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in North Carolina cities

Great Dane shelters & rescues in North Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics

Home

Adopt a Dog

Adopt a Great Dane

North Carolina

Great Dane puppies and dogs in North Carolina

Jump to:

Adopt a Great Dane near you in North Carolina

Below are our newest added Great Danes available for adoption in North Carolina. To see more adoptable Great Danes in North Carolina, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in North Carolina cities

Great Dane shelters & rescues in North Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics