Great Dane Adoption in Durham, NC: Great Dane Puppies for Sale in Durham, NC

Adopt a Great Dane near you in Durham, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Durham, North Carolina

These Great Danes are available for adoption close to Durham, North Carolina.

Kane

Great Dane

Male, Puppy

Raleigh, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, House-trained, Shots are up-to-date,

Story

Meet Kane the Dane 🐾; A Friendly Giant Looking for His Forever Home Kane is a sweet, gentle Great Dane with a heart as big as he is. He absolutely loves kids, adults, and other dogs, and makes friends wherever he goes. His favorite things include: Playing with sticks Long walks Eating (of course!) Cozy naps and lounging like the king he is Kane has a loving, easygoing personality and would do great in a home that can give him time, affection, and space to stretch those long legs. He’s being rehomed due to a relocation and financial hardship—this decision comes from love and wanting the best for him. If you’re looking for a loyal companion who will bring joy, calm, and lots of cuddles into your life, Kane could be your perfect match.

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Steve Harrington

Great Dane

Female 3 mos

Raleigh, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, House-trained,

Story

✨ Meet Steve Harrington ✨ Yes, that Steve Harrington, because much like the Stranger Things icon, this guy is impossibly handsome, wildly lovable, and rocking the most perfect floppy ears you’ve ever seen. Steve was found wandering downtown alone about two weeks ago, all skin and bones, trying to figure life out way too young. A friend scooped him up, and he’s been crashing with us ever since. While most rescues are full and the local shelter is closed for repairs (it’s rough out there for a homeless pup), we’re covering his care ourselves until we can find him what he really needs: a forever home. Steve is around 12 weeks old and already 25 pounds, so let’s be clear ... this is not a purse dog. The vet and I both suspect he’s a Great Dane mix, which means he’s on track to be a 100+ lb gentle giant. Big dog people, this is your moment. Despite his size, Steve is pure sunshine. He’s incredibly smart, crate trained, sleeping through the night, and hasn’t had an accident indoors in over a week (honestly, he’s showing off). He loves going for walks, sunbathing in the yard, chewing on sticks like it’s his job, and occasionally unleashing some truly impressive puppy zoomies. He plays beautifully with our two large dogs and can absolutely hold his own. Most importantly: Steve loves people. Like, deeply. Everyone he meets is immediately his best friend, and he’s generous with kisses. Consider yourself warned!

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Kane (Courtesy)

Great Dane

Male, Adult

Holly Springs, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Not good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

You can fill out an adoption application online on our official website. Online Adoption Application › KaneGreensboro, NC 16 monthsGreat Dane 90 poundsneuteredUp to date on shots? Yes Did you get the dog as a puppy or adult? Puppy (4 months) Has the dog had any formal training with a trainer? No Good with kids? Yes but wouldn’t recommend him in a home with one Good with strangers? No Good with chickens/ farm animals? UnsureGood with dogs of all sizes and gender? YesGood with cats? UnsureWhat does the dog enjoy? Loves running, playing ball, defluffing toys, attention What does the dog dislike? Strangers, sudden movements, car rides, feet being touchedCrate trained, house trained, leash trained? Yes, allDoes the dog know specific commands? Yes: Sit, down, stay, wait, knows not to go out of a door unless I say “let’s go”. Does the dog have any issues with health? NoAre vet records available? YesIs there agression? YesWhat are the triggers? Getting too hyper, Him doing something wrong and fearing discipline, Unknown situations, strangers (especially men) Food aggression? NoGuard toys? Sometimes (over other dogs)Has the dog been socialized in public? YesFood Allergies? ChickenEnvironmental Allergies? NoDoes the dog enjoy car rides? NoIs there any anxiety? SometimesWhat causes the anxiety? When he’s left aloneWhere does the dog normally sleep? CrateHow long does the dog go between potty breaks? Whenever he needs to go out or 8 hours during a work day (crated). Walk the dog to pottyDo you have steps and can the dog maneuver them? YesAny other issues the dog has that we need to monitor? NoWhy is the dog being rehomed? I can’t meet his needs. I am unsure of how to care properly for an aggressive dog. What do you feel would be a perfect home for the dog? Large fenced in backyard or someone who doesn’t mind taking him somewhere he can get out energy and run. This boy loves to run. No small kids but I think older kids would be fine (as long as the family knows the risks). Had the resources to get him the training he deserves, someone that is patient and kind and loving to him and willing to put in the work to understand his triggers. Could do well as an only dog but has always had doggie siblings.Visit this organization's web site to see any additional information available about this pet.January 6, 2026, 11:42 am

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Enid

Great Dane

Female, 6 mos

Garner, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, Shots are up-to-date,

Story

Welcome Wednesday and Enid to the ranch!!!Available for foster or forever now! GORGEOUS 6 month lab mix puppies Up-to-date and microchipped Good with dogs, cats and kids In Foster with master certified dog trainer Ready to go home now!!!!Statesville, NC Let's share them everywhere and get them home!!! ##2565560##

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Mozart

Great Dane

Male, Young

Buffalo Junction, VA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

We have a friend who breeds Great Danes and she offered this puppy to my daughter as a gift. He is a great dog, but she does not have the time required to care for him. He needs walking and playing time that she can't give. She is off to college in the fall and thought she would be taking him, but found out that no student housing will allow a big dog. He will need a home with a yard and someone who has time to walk him every day. He is very loving, completely house trained, and walks great on a leash. He accepts treats gently and knows how to sit and stay. He would do best in a house as the only pet, or with another large breed dog. He might be a problem for small children because in his enthusiasm he might knock them down.

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Durham, North Carolina.

Great Dane puppies and dogs in Durham, North Carolina

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Adopt a Great Dane near you in Durham, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

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These Great Danes are available for adoption close to Durham, North Carolina.

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Great Dane puppies and dogs in Durham, North Carolina

Learn More:

Adopt a Great Dane near you in Durham, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Durham, North Carolina

These Great Danes are available for adoption close to Durham, North Carolina.

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in nearby cities

Related breeds in Durham, North Carolina

Great Dane shelters & rescues in Durham, North Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog?

Great Dane basics

Great Dane basics